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BB30055: Genes and genomes
BB30055: Genes and genomes

... Proteome more complex than invertebrates…… no huge difference in domain number in humans BUT, frequency of domain sharing very high in human proteins (structural proteins and proteins involved in signal transduction and immune function) However, only 3 cases where a combination of 3 domain types ...
Grade 10 – Reproduction and Genetics
Grade 10 – Reproduction and Genetics

... Directions: Complete the following questions. You can only write on the lines provided, the goal is for you to write as specific as possible. Use your own words! 1. What is the difference between genes and chromosomes? Write a definition of each below and then explain how they are linked together. G ...
Gen660_Week4a_HGT_2014
Gen660_Week4a_HGT_2014

... * Environmental genes * Poorly characterized genes * Orphan genes (no homology to any known gene) * More mobile elements, phage sequences, repeats ...
Modern methods in biology
Modern methods in biology

... Chip-CGH to identify replication origins genome-wide Where does replication start from across the genome? How often does it start from each site? ...
DNA sequencer
DNA sequencer

... for promoter sequence  Sequences that follow promoter are genes  AA sequence determined by matching the nucleotide triplets to corresponding AA  ID protein encoded by this gene ...
Reproductive Technology
Reproductive Technology

... 3. Lets say the genome can be sequenced for $1,000. What if people could get their analysis through the mail, without every talking to a doctor. What are the pros and cons of this situation? What are some potential fall outs of receiving your genome analysis this way? How should the law control this ...
Word Definition 1 non-Mendelian genetics rules for inheritance that
Word Definition 1 non-Mendelian genetics rules for inheritance that

... mucus in their lungs, which makes it difficult for them to breathe an international effort to sequence all 3 billion bases that make up our DNA 10 Human Genome Project and to identify within this code more than 20,000 human genes 11 genome all the DNA in one cell 12 pedigree a family tree that track ...
APGenomes and Evolution 15 16
APGenomes and Evolution 15 16

... Humans have 23 pairs of chromosomes, while chimpanzees have 24 pairs Chromosomal rearrangements are thought to contribute to the generation of new species ...
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On bioinformatics

... obtained from the Protein Data Bank (PDB); Cn3D (a 3D-structure viewer); vector alignment search tool (VAST), and other protein structure resources ...
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1 BIOL 213 Fifth Exam All atoms, chemical bonding and structures

... Text). "Whereas the general transcription factors that assemble at the promoter are the same for all genes transcribed by RNA polymerase II, the gene regulatory proteins and the locations of their binding sites are different for different genes." ...
Statistical tests in Gene Set Analysis
Statistical tests in Gene Set Analysis

... the analyses of differential expression from high throughput profiling data. Wilcoxon Rank-Sum (WRS) test is one of the commonly used methods in gene set enrichment analysis because it is easy to implement and it eliminates the dichotomization of genes into significant and non-significant in a compe ...
Gramene: A Resource for Comparative Grass Genomics
Gramene: A Resource for Comparative Grass Genomics

... Ontologies can be indexed “objectively” by a computer.\ Computers can infer new knowledge ...
Mutations
Mutations

... D. Regulation and Development- especially important in shaping the way a complex organism develops from single fertilized cell. 1. Hox genes- controls organs and tissues that develop in various parts of the embryo a. Mutation in one of these “master control genes” can completely change organs that ...
Integrative Statistical Methods for Mapping Disease Genes
Integrative Statistical Methods for Mapping Disease Genes

... Biology is increasingly becoming a "data science": hundreds of thousands of human genomes are being sequenced; large amount of gene expression, protein-DNA interaction, and other types of genomic data are available. The key challenge is to extract "meaning" from data, to benefit our understanding of ...
Lecture 1 Genetics – An Overview Professor Jane Farrar School of
Lecture 1 Genetics – An Overview Professor Jane Farrar School of

... The same 3 billion base pairs of DNA are present in every cell of your body. Approximately 25,000 genes present in 23 pairs of human chromosomes in the 3 billion DNBA base pairs How does each cell function so differently? Not all genes are active in all cell types. Genes make RNA which is translate ...
How are we different? …at the RNA level.
How are we different? …at the RNA level.

... Are our Phenotypes 98.7% Similar? • Some apparent differences, – HIV susceptibility, epithelial neoplasms (cancers), malaria, and Alzheimers, ...
Genomics and Bioinformatics KEY CONCEPT Entire genomes are
Genomics and Bioinformatics KEY CONCEPT Entire genomes are

... organisms have been sequenced ...
Methods Used in Medical and Population Genetics
Methods Used in Medical and Population Genetics

... STUDIES: To capture both coding and non-coding ...
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No Slide Title

Lecture 4
Lecture 4

... Each 3 nucleotide code for one amino acid. •The first codon is the start codon, and usually coincides with the Amino Acid Methionine. (M which has codon code ‘ATG’) •The last codon is the stop codon and does NOT code for an amino acid. It is sometimes represented by ‘*’ to indicate the ‘STOP’ codon. ...
Chapter 6 Advanced Genetics
Chapter 6 Advanced Genetics

... Two types of Gene Changes Chromosomal changes – the # of chromosomes or the arrangement of genes on a chromosome Gene Mutations – a change in the sequence of bases in a gene. ...
Genomics - University of Missouri
Genomics - University of Missouri

Gen677_Week5a_HGT_2012
Gen677_Week5a_HGT_2012

... Often contain own mobility genes & sequences Evolve through gene acquisition & loss ...
1 Basic Genomics 1. How do you sequence DNA? Two methods
1 Basic Genomics 1. How do you sequence DNA? Two methods

... that can no longer “jump” and are just relics of previously-active TE’s. Pseudogenes – genes that are no longer functional (often duplicates of functional genes). Typically have a stop codon or frame-shift within their ORF. May have lost their promoter and not be expressed. Other sequences, such as ...
word doc
word doc

...  Females need two alleles for it to be expressed.  Thus, much more common in males: ...
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Genome evolution



Genome evolution is the process by which a genome changes in structure (sequence) or size over time. The study of genome evolution involves multiple fields such as structural analysis of the genome, the study of genomic parasites, gene and ancient genome duplications, polyploidy, and comparative genomics. Genome evolution is a constantly changing and evolving field due to the steadily growing number of sequenced genomes, both prokaryotic and eukaryotic, available to the scientific community and the public at large.
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