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Chapter 14 - FacStaff Home Page for CBU
Chapter 14 - FacStaff Home Page for CBU

... of molecules - a polymer. In turn, these abnormal elongated hemoglobin polymer structures distort the shape of the whole red blood cell. The abnormal RBC's can damage the vessels around them and the tissues that depend on the vessels for oxygen and nourishment. For example, the damaged RBC's can cau ...
Genetics Review 1. Describe Mendel`s experiments and know terms
Genetics Review 1. Describe Mendel`s experiments and know terms

... -- genotype/phenotype: genotype is the letter combination used to represent a gene, phenotype is the appearance -- heteroygous/homozygous: heterozygous is when an organism has two different alleles (Aa), homozygous is when the alleles are the same (aa or AA) -- dominant/recessive: dominant genes cov ...
Congenital & Genetic Disorders
Congenital & Genetic Disorders

... » Deletion = cause most serious problems and/or death » Translocation = broken part of chromosome becomes attached to non-homologous chromosome * Reciprocal or non-reciprocal (see next slide) – Change in chromosome number » Caused during meiosis by nondisjunction » Euploidy = normal number of chromo ...
Genome evolution: a sequence
Genome evolution: a sequence

... Looking for gene expression traits that explain QTLs – stands between genetic loci and some disease trait of interest Applied to obesity linkage (in mice) Further development use more data (not just expression), or gene subnetworks Ultimate goal is to build a model explaining phenotype by genotype t ...
Modeling Mendel*s Law
Modeling Mendel*s Law

... Mendel observed traits by controlling how pea plants were pollinated. ...
3.8 MB
3.8 MB

... the genetic  architecture of brain related phenotypes. • Imaging genetics has unique potential to identify novel drug  effects related to genetic mechanisms of brain disorders.  • imaging genetics has many opportunities for new directions  and new analyses as it enters adolescence.  Its future impac ...
population genetics File
population genetics File

...  Sometimes one or a few individuals disperse and become the founders of a new, isolated population at some distance from their place of origin.  These pioneers are not likely to have all the alleles present in the source population.  In some cases, previously rare alleles in the source population ...
notes (p.49-52)
notes (p.49-52)

... is the Wright-Fisher model. We imagine that, tracing back in time, each child chooses its single parent at random, independently of the other children. This resembles reality in the case in which every parent produced a very large number of offspring (much larger than N ), which are then randomly cu ...
Chapter 5 - Biography and the Sociological Imagination
Chapter 5 - Biography and the Sociological Imagination

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Complex inheritance of traits
Complex inheritance of traits

... from the male and one from the female. However, for some traits, there may be three or more (even 100!) possible alleles (in the population), each resulting in a different phenotype. Usually, one allele is dominant over all others, others are dominant over certain ones and recessive to the others an ...
BioA414 Handout VII-2017
BioA414 Handout VII-2017

... Bottleneck and founder effects • Sampling effects  occurs in natural populations – From founder effects  a populati on is established by a s mall number of breedi ng indi vi duals – Populati on size remains small / many generations – Subpopul ations are isolated – Chance pl ays a significant role ...
Gregor Mendel Power Point File
Gregor Mendel Power Point File

... Why pea plants??? There was a long-standing tradition of breeding pea plants at the monastery where Mendel lived and worked ...
Patterns of Inheritance: Genetics Chapt. 10
Patterns of Inheritance: Genetics Chapt. 10

... acid substitution in the beta chains of hemoglobin. When oxygen concentration is low, sickling of cells occurs. Heterozygotes make enough good beta-chain hemoglobin that they do not suffer as long as oxygen concentrations remain high, such as at sea-level. ...
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TG - Science-with

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AP Biology 1. Small Population
AP Biology 1. Small Population

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Genetics and Personality
Genetics and Personality

... family members with the degree of similarity in personality trait If a trait is highly heritable, family members with greater genetic relatedness should be more similar to one another on the trait than family members who are less closely genetically related Copyright © 2005 The McGraw-Hill Companies ...
Gene Mapping and Drosophila
Gene Mapping and Drosophila

... 1. Genetic analysis has shown that the recessive genes an ("Anther ear"). br ("brachytic") and f ("fine stripe") are all found on chromosome #1 of maize (corn). When a plant that is heterozygous1 for each of these markers is test-crossed with a homozygous recessive plant, the following results are o ...
Ch. 10 Mendel`s Genetics
Ch. 10 Mendel`s Genetics

... equally. ...
evolution and natural selection - CAPE Biology Unit 1 Haughton
evolution and natural selection - CAPE Biology Unit 1 Haughton

... • Structural similarities between organisms suggests the existence of an evolutionary process. • Result of progressive adaptation. ...
Punnett Square
Punnett Square

... Hair color is a perfect example of a trait What color hair should their children have? Prince Charming is blond ...
Genetic constitution of a population
Genetic constitution of a population

... chromosomes will be the ones transmitted to the offspring If homologous chromosomes contained genes that influence a trait differently (allele) then two offspring will look different, hence the observed variation ...
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Notes

... - Individuals within a species ___________ in their specific ____________________________ - Phenotypic variations often reflect genetic variations - _________________________ variation: differences among individuals in the composition of their genes or other DNA sequences - Some heritable phenotypic ...
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No Slide Title

... Factors will be explained in a little while. ...
Physical Anthropology
Physical Anthropology

... The study of variation or genetic differences between people and populations, to understand the differences between people. Based on: ...
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Heritability of IQ

Research on heritability of IQ infers from the similarity of IQ in closely related persons the proportion of variance of IQ among individuals in a study population that is associated with genetic variation within that population. This provides a maximum estimate of genetic versus environmental influence for phenotypic variation in IQ in that population. ""Heritability"", in this sense, ""refers to the genetic contribution to variance within a population and in a specific environment"". There has been significant controversy in the academic community about the heritability of IQ since research on the issue began in the late nineteenth century. Intelligence in the normal range is a polygenic trait. However, certain single gene genetic disorders can severely affect intelligence, with phenylketonuria as an example.Estimates in the academic research of the heritability of IQ have varied from below 0.5 to a high of 0.8 (where 1.0 indicates that monozygotic twins have no variance in IQ and 0 indicates that their IQs are completely uncorrelated). Some studies have found that heritability is lower in families of low socioeconomic status. IQ heritability increases during early childhood, but it is unclear whether it stabilizes thereafter. A 1996 statement by the American Psychological Association gave about 0.45 for children and about .75 during and after adolescence. A 2004 meta-analysis of reports in Current Directions in Psychological Science gave an overall estimate of around 0.85 for 18-year-olds and older. The general figure for heritability of IQ is about 0.5 across multiple studies in varying populations. Recent studies suggest that family environment (i.e., upbringing) has negligible long-lasting effects upon adult IQ.
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