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Targeting the Noncoding Genome with CRISPR
Targeting the Noncoding Genome with CRISPR

... “Compared to the sequences of protein-coding genes, we don’t know much about noncoding regulatory elements,” said study coauthor Neville Sanjana, of the New York Genome Center and New York University who was a postdoc in Zhang’s lab. “Our study and other gene-editing screens will enable us to discov ...
Sex-linked Traits
Sex-linked Traits

... Since the father can contribute only a Y, the mother determines if the son will have the defective alleles. ...
Minutes
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... colonization and symptom development in diseases caused by Sclerotinia spp., has been well established through a number of independent physiological experiments. Using a mutant-based genetic approach, oxalic acid production has also been reported to be an essential pathogenicity determinant for S. s ...
Science of Addiction WebquestKEY
Science of Addiction WebquestKEY

... Neurons communicate via the synapse 6. Define synapse: Information from one neuron flows to another neuron across a small gap called a synapse Click the “Back” button and return to the page titled “The New Science of Addiction: Genetics and the Brain”. Follow the link, “Drugs alter the Brain’s Rewar ...
Natural Selection
Natural Selection

... parents into one individual, forming an individual which varies from either parent. – This variation is normally a random event. – In our example, let’s say two mutated animals mate with one another. Let’s look at their offspring. ...
Conference title
Conference title

... Hornett, E. A. and C. W. Wheat (2012) Quantitative RNA-Seq analysis in nonmodel species: assessing transcriptome assemblies as a scaffold and the utility of ...
Biopsychology and the Foundations of Neuroscience Chapter 3
Biopsychology and the Foundations of Neuroscience Chapter 3

... flourish and reproduce; those that are poorly adapted will tend to leave fewer progeny, and their line may die out. ...
Nedchromosnotes2jan2014NED 20 KB
Nedchromosnotes2jan2014NED 20 KB

... in common that they are all caused by nondisjunction (NDJ) events; the numbers next to each condition refer to what? Important terms you need to and should know but I do not have time to redefine because they should be hardwired by now are haploid, diploid, nucleosome, chromatin, histone, centromere ...
Beyond Mendel
Beyond Mendel

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Mendelian Genetics
Mendelian Genetics

... is determined by the alleles present for each trait. The type of genes an individual has. • Phenotype: Physical appearance of a trait. It is the expression of the genotype. ...
“What it Means to be 98% Chimpanzee” by Jonathan Marks and
“What it Means to be 98% Chimpanzee” by Jonathan Marks and

... no less than 25% of our DNA with bananas, for several basic reasons that Marks elucidates. First, there are only 4 bases used by DNA, meaning that at any one point, two sequences have a 25% chance of sharing a base. Second, many DNA segments result from ancient homologies and are shared across speci ...
Detecting Allelic Effects
Detecting Allelic Effects

... genome (and similar numbers in model organisms) is an essential step to increase our understanding of basic biological processes, to identify the causative genetic variants responsible for common human diseases. Genes that harbor regulatory variants in cis-acting elements can be identified by differ ...
Glossary of Terms - Liverpool Womens NHS Foundation Trust
Glossary of Terms - Liverpool Womens NHS Foundation Trust

... interacting with environmental factors to produce a liability to a particular disorder. A person is affected if his or her liability is above a certain threshold. MUTATION A mutation refers to any change from the normal to an altered form of a particular gene. This may be disease causing or a benign ...
EXPLORING DEAD GENES
EXPLORING DEAD GENES

... C.elegans in attempt to estimate the total number in humans. Found few pseudogenes that are apparently due to processing in the worm genome Found large uncharacterized gene family that makes up 2/3 of dead genes Arms of chromosome are an unreliable for encoding genes but more likely to spawn new pro ...
Dihybrid Crosses Note
Dihybrid Crosses Note

... 7. An allele is a form of a gene. In a dihybrid cross HhSs x hhss, how many alleles does a kitten inherit from the mother? _______ 8. How many alleles does a kitten inherit from the father? _______. 9. Gametes, which are sex cells, carry the alleles. Why must a gamete carry one allele (represented b ...
Sex-Influenced Traits
Sex-Influenced Traits

... Sex-influenced traits appear more often in one sex than the other. Although these traits may appear more often in males than in females, they are not sex-linked, because they do not appear on the sex chromosomes. The genes for sex-influenced traits are on the autosomes not the sex chromosomes. Sex-i ...
What we*ll sense and perceive* in this chapter:
What we*ll sense and perceive* in this chapter:

...  Difference threshold: the minimum difference (in color, pitch, weight, temperature, etc) for a person to be able to detect the difference half the time.  Weber’s law refers to the principle that for two stimuli to be perceived as different, they must differ by a minimum percentage:  2 percent of ...
Hypergeometric Tests for Gene Lists
Hypergeometric Tests for Gene Lists

... Back to the question Are there any GO terms that have a larger than expected subset of our selected genes in their annotation list? If so, these GO terms will give us insight into the functional characteristics of the gene list. The common test is for over representation, but one can also test for ...
Genetic Engineering PowerPoint
Genetic Engineering PowerPoint

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Lesson Overview

... Genetics Joins Evolutionary Theory How is evolution defined in genetic terms? In genetic terms, evolution is any change in the relative frequency of alleles in the gene pool of a population over time. ...
go-interpretation-analysis-2014
go-interpretation-analysis-2014

... tool available on the website  Beginning to use our own data in the same way our users most commonly use it  This was not a goal of the GO grant. Instead, we had proposed:  We will define test datasets that will allow software developers to benchmark their products. The GOC web site provides an e ...
Mendelian Genetics part 4
Mendelian Genetics part 4

... A. This term refers to genes found on the sex chromosomes; 95% of the time it mainly refers to the X chromosome. (Think X when it is seX linked.) 1. This is because both sexes have at least one X chromosome in their genome. 2. XX (Female and homologous) ; XY (Male and heterologous) B. Sex chromosome ...
New Relationships Medline Full (prev. 5 yr)
New Relationships Medline Full (prev. 5 yr)

... Users normally go directly to abstracts, skipping the gene Users estimate that 25% of the time they find the papers interesting enough to download the full articles Wrong genes not necessarily lead to non-relevant papers. This is probably because we do a good job getting the diseases right. ...
Evolution and Morality
Evolution and Morality

... altruistic behaviour, making it an expression of our genes that emerges from normal development. • How can such rules compete with (also evolution-based) impulses to selfish behaviour? ...
Evolution and Differentiation
Evolution and Differentiation

... different roles but they are also physically different. ...
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Biology and consumer behaviour

Consumer behaviour is the study of the motivations surrounding a purchase of a product or service. It has been linked to the field of psychology, sociology and economics in attempts to analyse when, why, where and how people purchase in the way that they do. However, little literature has considered the link between our consumption behaviour and the basics of our being, our biology. Segmentation by biological driven demographics such as sex and age are already popular and pervasive in marketing. As more knowledge and research is known, targeting based on a consumers biology is of growing interest and use to marketers.As human machines being made up of cells controlled by our brain to influence aspects of our behaviour, there must be some influence of biology on our consumer behaviour and how we purchase as well. The nature versus nurture debate is at the core of how much biology influences these buying decisions, because it argues the extent to which biological factors influence what we do, and how much is reflected through environmental factors. Neuromarketing is of interest to marketers in measuring the reaction of stimulus to marketing. Even though we know there is a reaction, the question of why we consume the way we do still lingers, but it is a step in the right direction. Biology helps to understand consumer behaviour as it influences consumption and aids in the measurement of it.Lawson and Wooliscroft (2004) drew the link between human nature and the marketing concept, not explicitly biology, where they considered the contrasting views of Hobbes and Rousseau on mankind. Hobbes believed man had a self-serving nature whereas Rousseau was more forgiving towards the nature of man, suggesting them to be noble and dignified. Hobbes saw the need for a governing intermediary to control this selfish nature which provided a basis for the exchange theory, and also links to Mcgregor’s Theory of X and Y, relevant to management literature. He also considered cooperation and competition, relevant to game theory as an explanation of man’s motives and can be used for understanding the exercising of power in marketing channels. Pinker outlines why the nature debate has been suppressed by the nurture debate in his book The Blank Slate.
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