2005-05_Purdue_edimmer
... electronic techniques (InterPro2GO, SPKW2GO, EC2GO) • Compared manually-curated test set of GO annotated proteins with the electronic annotations • InterPro2GO = most coverage • EC2GO = 67 % of predictions exactly match the manual GO annotation. • 91-100 % of time the 3 mappings predicted GO terms w ...
... electronic techniques (InterPro2GO, SPKW2GO, EC2GO) • Compared manually-curated test set of GO annotated proteins with the electronic annotations • InterPro2GO = most coverage • EC2GO = 67 % of predictions exactly match the manual GO annotation. • 91-100 % of time the 3 mappings predicted GO terms w ...
Tools for Comparing Bacterial Genomes
... As can be seen in > Fig. 2, the genes in this chromosome are strongly favoring one strand: the positive strand for the first (right) half and the negative strand for the second (left) half of the chromosome. These happen to be the leading strand during replication. Replication starts at the origin, ...
... As can be seen in > Fig. 2, the genes in this chromosome are strongly favoring one strand: the positive strand for the first (right) half and the negative strand for the second (left) half of the chromosome. These happen to be the leading strand during replication. Replication starts at the origin, ...
Genetics of narcolepsy and other major sleep disorders
... HLA susceptibility allele across all ethnic groups. The more striking fact is that 88–98% of patients affected by narcolepsy with clear cataplexy are HLA DQB1*0602 positive. This allele strongly increases the susceptibility for cataplexy although 41% of patients without cataplexy are carriers. DRB1 ...
... HLA susceptibility allele across all ethnic groups. The more striking fact is that 88–98% of patients affected by narcolepsy with clear cataplexy are HLA DQB1*0602 positive. This allele strongly increases the susceptibility for cataplexy although 41% of patients without cataplexy are carriers. DRB1 ...
GCCF Outcrossing Policy - The Governing Council of the Cat Fancy
... GCCF policy on the use of outcrossing in cat breeding programmes Outcrossing is the introduction of new genetic material into a breeding line or a breed’s gene pool. It involves the mating together of cats of different varieties, different breeds or of a pedigree cat to a ‘foundation cat’ of unreco ...
... GCCF policy on the use of outcrossing in cat breeding programmes Outcrossing is the introduction of new genetic material into a breeding line or a breed’s gene pool. It involves the mating together of cats of different varieties, different breeds or of a pedigree cat to a ‘foundation cat’ of unreco ...
The nucleotide sequence of Saccharomyces cerevisiae
... high number of Ty and LTR elements in that region should give rise to large numbers of genome rearrangements (inversions, deletions and reciprocal translocations), which could explain this difference with the flanking regions. The construction of gene arrangement has led to general features that pro ...
... high number of Ty and LTR elements in that region should give rise to large numbers of genome rearrangements (inversions, deletions and reciprocal translocations), which could explain this difference with the flanking regions. The construction of gene arrangement has led to general features that pro ...
A systemic gene silencing method suitable for high throughput
... Background: Ceratopteris richardii is a useful experimental system for studying gametophyte development and sexual reproduction in plants. However, few tools for cloning mutant genes or disrupting gene function exist for this species. The feasibility of systemic gene silencing as a reverse genetics ...
... Background: Ceratopteris richardii is a useful experimental system for studying gametophyte development and sexual reproduction in plants. However, few tools for cloning mutant genes or disrupting gene function exist for this species. The feasibility of systemic gene silencing as a reverse genetics ...
Börjeson–Forssman–Lehmann syndrome: defining
... Mutations in the zinc finger protein ZIC3 are associated with visceral heterotaxy or situs abnormalities [23]. F9 is the well known coagulation factor IX associated with hemophilia B. MCF2, also called DBL, is an oncogene, where no clinical condition could be attributed yet to the loss of the MCF2 g ...
... Mutations in the zinc finger protein ZIC3 are associated with visceral heterotaxy or situs abnormalities [23]. F9 is the well known coagulation factor IX associated with hemophilia B. MCF2, also called DBL, is an oncogene, where no clinical condition could be attributed yet to the loss of the MCF2 g ...
TCU Taiwan Championship Poster
... Filamentous phage can only infect bacteria with F pili. Its life cycle described in following steps: Adsorption: In this step, M13 and M13KO7 are the same. Both of their pilus attachment protein gp3 and gp6 will help them bind on F pilus, then the phage will move into host cell by F pilus and take o ...
... Filamentous phage can only infect bacteria with F pili. Its life cycle described in following steps: Adsorption: In this step, M13 and M13KO7 are the same. Both of their pilus attachment protein gp3 and gp6 will help them bind on F pilus, then the phage will move into host cell by F pilus and take o ...
PDF
... absence is striking, as the possibility of such genetic polymorphism has attracted much interest. Examples of studies in the laboratory and the field span from work on cheater-cooperator polymorphisms [7–15] to investigations of genetic variation in microbial pathogens [16, 17]. The possibility that ...
... absence is striking, as the possibility of such genetic polymorphism has attracted much interest. Examples of studies in the laboratory and the field span from work on cheater-cooperator polymorphisms [7–15] to investigations of genetic variation in microbial pathogens [16, 17]. The possibility that ...
Given a Punnett square. Analyze a Dihybrid cross
... A Punnett square is a chart which shows/predicts all possible gene combinations in a cross of parents (whose genes are known). Punnett squares are named for an English geneticist, Reginald Punnett. He discovered some basic principles of genetics, including sex linkage and sex determination. Use the ...
... A Punnett square is a chart which shows/predicts all possible gene combinations in a cross of parents (whose genes are known). Punnett squares are named for an English geneticist, Reginald Punnett. He discovered some basic principles of genetics, including sex linkage and sex determination. Use the ...
Biosafety Protocol Registration Form
... D-3: Experiments involving the use of infectious DNA or RNA viruses or defective DNA or RNA viruses in the presence of a helper virus in tissue culture systems. 1. Experiment is likely to enhance pathogenicity. Yes No 2. Experiment extends the host range. Yes No D-4: Experiments involving whole anim ...
... D-3: Experiments involving the use of infectious DNA or RNA viruses or defective DNA or RNA viruses in the presence of a helper virus in tissue culture systems. 1. Experiment is likely to enhance pathogenicity. Yes No 2. Experiment extends the host range. Yes No D-4: Experiments involving whole anim ...
User guide
... Genome‐wide association studies (GWAS) have greatly expanded our knowledge of common diseases by discovering many susceptibility common variants. Several gene‐set based methods that are complementary to the typical single marker / gene analysis have recently been applied to GWAS datasets to detec ...
... Genome‐wide association studies (GWAS) have greatly expanded our knowledge of common diseases by discovering many susceptibility common variants. Several gene‐set based methods that are complementary to the typical single marker / gene analysis have recently been applied to GWAS datasets to detec ...
article in press
... First, the set of 64 codons of the genetic code was partitioned into two groups of 32 codons depending on whether the third base of triplets is necessary or not to define unambiguously an amino acid or a stop signal (property 1). Rumer reported a symmetry by base substitutions that alters property 1 ...
... First, the set of 64 codons of the genetic code was partitioned into two groups of 32 codons depending on whether the third base of triplets is necessary or not to define unambiguously an amino acid or a stop signal (property 1). Rumer reported a symmetry by base substitutions that alters property 1 ...
A global view of pleiotropy and phenotypically
... with respect to their phenotype profiles across many conditions. For example, the combination of sensitivity to benomyl, cycloheximide, hydroxyurea, and hygromycin B in cluster 1 (Figure 2B) groups genes enriched for two functional categories, transcription from RNA Pol II promoters (P¼1.6 105) an ...
... with respect to their phenotype profiles across many conditions. For example, the combination of sensitivity to benomyl, cycloheximide, hydroxyurea, and hygromycin B in cluster 1 (Figure 2B) groups genes enriched for two functional categories, transcription from RNA Pol II promoters (P¼1.6 105) an ...
The Evolution of Populations
... Every now and then, though, a mutational change is adaptive (and even less often, both adaptive and dominant or codominant), i.e., novel functions or novel expression of old functions "On rare occasions, however, a mutant allele may actually fit its bearer to the environment better and enhance t ...
... Every now and then, though, a mutational change is adaptive (and even less often, both adaptive and dominant or codominant), i.e., novel functions or novel expression of old functions "On rare occasions, however, a mutant allele may actually fit its bearer to the environment better and enhance t ...
CHAPTER 20 ANTIBIOTIC RESISTANCE
... › The outer layer of gram-negative organisms Pumping keeps the concentration of antibiotic below levels that would destroy the cell Genes that code for efflux pumps are located on plasmids and transposons. Transposons are sequences of DNA that can move or transpose move themselves to new positions w ...
... › The outer layer of gram-negative organisms Pumping keeps the concentration of antibiotic below levels that would destroy the cell Genes that code for efflux pumps are located on plasmids and transposons. Transposons are sequences of DNA that can move or transpose move themselves to new positions w ...
Methylation of an upstream Alu sequence on the Imprinted H19
... Alu sequences are repetitive 300 base pair, site specific elements interspersed in primate genomes. They contain numerous CpG islands that are sometimes methylated. Alu methylation differs between somatic and germ cell DNA, suggesting a possible role for Alu sequences in genomic imprinting. The obje ...
... Alu sequences are repetitive 300 base pair, site specific elements interspersed in primate genomes. They contain numerous CpG islands that are sometimes methylated. Alu methylation differs between somatic and germ cell DNA, suggesting a possible role for Alu sequences in genomic imprinting. The obje ...
Question 1
... Despite very good fidelity, some mistakes are not fixed during or after DNA replication. An incorrect nucleotide insertion will be passed on to one of the daughter cells (the other daughter will receive the correct base-pair). If the nucleotide change is within a gene, it has the possibility of alte ...
... Despite very good fidelity, some mistakes are not fixed during or after DNA replication. An incorrect nucleotide insertion will be passed on to one of the daughter cells (the other daughter will receive the correct base-pair). If the nucleotide change is within a gene, it has the possibility of alte ...
Crumbs and Xpd in mitosis
... this screen was found to be required for the regulation of spindle dynamics and chromosome segregation [3]. Our recent work [4], which identified Galla and Xpd as new partners of Crumbs (Crb) in mitosis, presents another case of fruitful genetic screen. Crb is a conserved cell membrane protein essen ...
... this screen was found to be required for the regulation of spindle dynamics and chromosome segregation [3]. Our recent work [4], which identified Galla and Xpd as new partners of Crumbs (Crb) in mitosis, presents another case of fruitful genetic screen. Crb is a conserved cell membrane protein essen ...
Cat Health Network Feline SNP Chip Studies Lay Language
... health. The tailless mutation of the Manx cat breed affects spine and tail development, the breed being purposely selected to have no tail. If the tail is too short, vertebrae of the lower back are missing, leading to poor development of nerves, thus cats can be lame and not be able to control their ...
... health. The tailless mutation of the Manx cat breed affects spine and tail development, the breed being purposely selected to have no tail. If the tail is too short, vertebrae of the lower back are missing, leading to poor development of nerves, thus cats can be lame and not be able to control their ...
Genetics Notes PDF
... 2. What was Mendel's role in the history of genetics? A: He was the father of genetics. ...
... 2. What was Mendel's role in the history of genetics? A: He was the father of genetics. ...
Functional genomics of plant photosynthesis in
... to PSI. The positively charged N-terminal domain of PsaF in Chlamydomonas and plants is not present in cyanobacteria, and it has been hypothesized that the evolution of this domain allowed the formation of a stable complex between plastocyanin and PSI, and thus fast electron transfer6. Site-directed ...
... to PSI. The positively charged N-terminal domain of PsaF in Chlamydomonas and plants is not present in cyanobacteria, and it has been hypothesized that the evolution of this domain allowed the formation of a stable complex between plastocyanin and PSI, and thus fast electron transfer6. Site-directed ...
Genetic engineering
Genetic engineering, also called genetic modification, is the direct manipulation of an organism's genome using biotechnology. It is therefore a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms. New DNA may be inserted in the host genome by first isolating and copying the genetic material of interest using molecular cloning methods to generate a DNA sequence, or by synthesizing the DNA, and then inserting this construct into the host organism. Genes may be removed, or ""knocked out"", using a nuclease. Gene targeting is a different technique that uses homologous recombination to change an endogenous gene, and can be used to delete a gene, remove exons, add a gene, or introduce point mutations.An organism that is generated through genetic engineering is considered to be a genetically modified organism (GMO). The first GMOs were bacteria generated in 1973 and GM mice in 1974. Insulin-producing bacteria were commercialized in 1982 and genetically modified food has been sold since 1994. Glofish, the first GMO designed as a pet, was first sold in the United States December in 2003.Genetic engineering techniques have been applied in numerous fields including research, agriculture, industrial biotechnology, and medicine. Enzymes used in laundry detergent and medicines such as insulin and human growth hormone are now manufactured in GM cells, experimental GM cell lines and GM animals such as mice or zebrafish are being used for research purposes, and genetically modified crops have been commercialized.