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Supplementary materials
Supplementary materials

... file from the NCBI ftp site (ftp://ftp.ncbi.nih.gov/pub/HomoloGene/), and extracted the clusters in which only one gene appeared for each species examined. Based on ...
ppt
ppt

... "for his discoveries concerning the role played by the chromosome in heredity" ...
Bellevue ISD
Bellevue ISD

... separately and discovered certain patterns in the way traits are inherited in peas. • Mendel’s work has become the basis of genetics, the study of heredity. ...
Document
Document

... Principle of Independent Assortment: • states that genes for different traits segregate independently during the formation of gametes • Independent assortment accounts for the many genetic variations observed in plants animals, & other organisms. ...
Bis2A 12.2 Eukaryotic Transcription
Bis2A 12.2 Eukaryotic Transcription

... 2 Eukaryotic Elongation and Termination Following the formation of the preinitiation complex, the polymerase is released from the other transcription factors, and elongation is allowed to proceed as it does in prokaryotes with the polymerase synthesizing premRNA in the 5' to 3' direction. As discuss ...
Therapeutic Strategies for the Inherited Neuropathies
Therapeutic Strategies for the Inherited Neuropathies

... independently identified the first genetic cause of CMT (Lupski et al., 1991; Raeymaekers et al., 1991). As is now well known, both groups demonstrated that CMT1A, the most common form of CMT1, is caused by a 1.4-Mb duplication within chromosome 17p11.2, in the region containing the PMP22 gene. Repo ...
Qualitative Analysis of Regulatory Graphs: A Computational Tool
Qualitative Analysis of Regulatory Graphs: A Computational Tool

... level of gene gi corresponds to a threshold from which an interaction (with source gi ) becomes functional (thus for each gene, the maximum level equals at most the number of interactions exerted by this gene). Let Ij be the set of incoming interactions (or inputs set) of gj . For any gene gj , a su ...
University of Groningen DNA-based asymmetric catalysis
University of Groningen DNA-based asymmetric catalysis

... with enzymes. Although small molecule catalysts can have high catalytic activity, they are generally still outperformed by enzymes. However, the possibility to catalyze a wide variety of reactions, renders small molecule catalysts very important for applications of asymmetric catalysis in industry,8 ...
Gene Section JUN (V-Jun sarcoma virus 17 oncogene homolog (avian))
Gene Section JUN (V-Jun sarcoma virus 17 oncogene homolog (avian))

5 Genetic Analysis of Kidney Disease in Mice
5 Genetic Analysis of Kidney Disease in Mice

... or D2 males. We detected a significant QTL on distal Chr 2 (peak 76 cM; CI 56-99 cM) in the B6xD2 cross and an overlapping suggestive QTL in the B6xA/J cross, where D2 and A/J mice contributed susceptibility alleles. Second, we aligned the mouse QTL on Chr 2 with homologous CKD QTL on rat Chr 3 and ...
poor homologous synapsis 1 a novel gene required for homologous
poor homologous synapsis 1 a novel gene required for homologous

... primer34C: was designed to amplify TC77059. This sequence is more distantly related to AW066336, e-112, 269/289 (93%). The gene represented by ESTs AW066336 and AW066011 appears to lie on chromosome 5. The PCR primers, primer34C, detects the related sequence on chromosome 4. ...
Regional DNA Hypermethylation at D17S5
Regional DNA Hypermethylation at D17S5

... studies of colon (2) and brain tumors (1), establish that D17S5 hy permethylation is tightly coupled to 17p deletions and p53 gene mu tations in human cancers. Our results in renal cancer strongly suggest that this hypermethylation precedes the other two events. If so, hy was one tumor (Fig. 3) whic ...
Human microRNA target analysis and gene ontology clustering by
Human microRNA target analysis and gene ontology clustering by

... transcribed from the genomic DNA by RNA polymerase II. The size of this primary product varies from 100- to 1000nucleotides in length. Then, the pri-miRNA is truncated by Drosha and DGCR8 to form a hairpin loop precursor called pre-miRNA [3]. The 60–70 nucleotide long premiRNA is loaded to Exportin ...
Final Review
Final Review

... Put the phases of mitosis in order: • Metaphase telophase anaphase prophase ...
Module 6: Enzymatic Function
Module 6: Enzymatic Function

... shown in Figure 6.19 are obtained. Results are thus likely to be less specific, and you may need to spend some time determining which is the best fit for your protein. In figure 6.19 the choice of “DNA-directed DNA polymerase” would be most appropriate since Ksed_00020 is not an “RNA-directed DNA po ...
QUANTITATIVE TRAITS - QUALITATIVE TRAITS AND
QUANTITATIVE TRAITS - QUALITATIVE TRAITS AND

... Quantitative genetics (Inheritance of Multiple Genes) The phenotypic traits of the different organisms may be of two kinds, viz., qualitative and quantitative. The qualitative traits are the classical Mendelian traits of kinds such as form (e.g., round or wrinkle seeds of pea); structure (e.g., horn ...
Chapter 12
Chapter 12

... Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
5 BLY 122 Lecture Notes (O`Brien) 2010 II. Protists (Chapter 29) A
5 BLY 122 Lecture Notes (O`Brien) 2010 II. Protists (Chapter 29) A

... d. This changed in the 1980s when DNA sequencing data showed that eukaryotic organelles had chromosomes that differed from nuclear genetic material as Margulis had predicted 2. The Mitochondrion & Endosymbiosis Theory a. Larger anaerobic eukaryotes engulfed aerobic prokaryotes, which became endosym ...
Inferring Speciation Processes from Patterns of Natural Variation in
Inferring Speciation Processes from Patterns of Natural Variation in

... investigate speciation is proper sampling. Because they focus on recent evolutionary events that generate variation among individuals, population genetic studies typically include numerous closely related individuals to avoid the confounding effects of many overlapping events. Because bacteria, arch ...
Lecture 1: overview of C. elegans as an experimental organism
Lecture 1: overview of C. elegans as an experimental organism

... chromosomes segregate independently of one another. Genes that are physically linked to each other by the virtue of being on the same chromosome segregate with each other unless separated from one another by recombination during meiosis. The closer two genes are to each other on a chromosome, the mo ...
Conclude chromosomes and inheritance - April 9
Conclude chromosomes and inheritance - April 9

... – Alternatively, sister chromatids may fail to separate during meiosis II. • As a consequence of nondisjunction, some gametes receive two of the same type of chromosome and another gamete receives no copy. • Offspring resulting from fertilization of a normal gamete with one after nondisjunction will ...
Pleiotropy and the Genomic Location of Sexually Selected Genes
Pleiotropy and the Genomic Location of Sexually Selected Genes

... crosses cannot identify the genes or their pleiotropic effects. In addition, my survey is not constrained by maternal effects, Y effects, and cytoplasmic effects, all of which are indistinguishable from X effects when measured using reciprocal crosses. Genes were deemed pleiotropic if they contribut ...
chapter 15
chapter 15

...  An individual who inherits two X chromosomes usually develops as a female.  An individual who inherits an X and a Y chromosome usually develops as a male.  Other animals have different methods of sex determination.  The X-0 system is found in some insects. Females are XX, males are X.  In bird ...
The global repressor FliZ antagonizes gene
The global repressor FliZ antagonizes gene

... S2A) (21,22) and recent publications indicate that FliZ acts as a DNA-binding regulator in other bacterial species (23). This suggested that the ability of FliZ to antagonize sS-dependent gene expression (10) might be due to binding to sS-controlled promoters rather than to sS itself. This possibili ...
Analyses of human–chimpanzee orthologous gene
Analyses of human–chimpanzee orthologous gene

... mouse, and rat orthologs. The orthology of these gene alignments is considered unambiguous. Ka/Ks ratios for each alignment were previously calculated by the Chimpanzee Sequencing and Analysis Consortium (2005) as well as estimates of lineage-specific protein changes. Given the similarity between hu ...
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History of genetic engineering

Genetic modification caused by human activity has been occurring since around 12,000 BC, when humans first began to domesticate organisms. Genetic engineering as the direct transfer of DNA from one organism to another was first accomplished by Herbert Boyer and Stanley Cohen in 1973. Advances have allowed scientists to manipulate and add genes to a variety of different organism and induce a range of different effects. Since 1976 the technology has been commercialised, with companies producing and selling genetically modified food and medicine.
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