PowerPoint File, 13.82 MB
... (SNH Model), yielding non-parental gene complements that have phenotypic consequences (transgressive segregation?) • Genetic variation arising from SNH model would NOT be detected in typical genome scans ...
... (SNH Model), yielding non-parental gene complements that have phenotypic consequences (transgressive segregation?) • Genetic variation arising from SNH model would NOT be detected in typical genome scans ...
RidgeRace: ridge regression for continuous ancestral character
... and Contml (Felsenstein, 1993). One of the simplest ways to reconstruct a continuous ancestral character state was established with Felsenstein’s algorithm for ‘Phylogenetic Independent Contrasts’ (Felsenstein, 1985). In the Phylogenetic Independent Contrasts algorithm, ancestral values are computed ...
... and Contml (Felsenstein, 1993). One of the simplest ways to reconstruct a continuous ancestral character state was established with Felsenstein’s algorithm for ‘Phylogenetic Independent Contrasts’ (Felsenstein, 1985). In the Phylogenetic Independent Contrasts algorithm, ancestral values are computed ...
The Genetics of Alcohol Metabolism
... erties. These SNPs and their effects have been widely studied in different populations (see other articles in this issue). There are three different ADH1B alleles that alter the amino acid sequence of the encoded β sub unit (Table 2). The ADH1B*1 allele encodes the β1 subunit that has argi nine (A ...
... erties. These SNPs and their effects have been widely studied in different populations (see other articles in this issue). There are three different ADH1B alleles that alter the amino acid sequence of the encoded β sub unit (Table 2). The ADH1B*1 allele encodes the β1 subunit that has argi nine (A ...
Animal Genetics PowerPoint
... Each male gene that controls a specific trait combines with the female gene for the same trait. A pair of genes that control a specific trait are called alleles. If both genes that control a specific trait are alike, they are said to be homozygous. For example, if the male gene for hair color is bla ...
... Each male gene that controls a specific trait combines with the female gene for the same trait. A pair of genes that control a specific trait are called alleles. If both genes that control a specific trait are alike, they are said to be homozygous. For example, if the male gene for hair color is bla ...
C1. Mendel`s work showed that genetic determinants are inherited in
... Note: smooth pods are the same as inflated pods. C11. The genotypes are 1 YY : 2 Yy : 1 yy. The phenotypes are 3 yellow : 1 green. C12. Offspring with a nonparental phenotype are consistent with the idea of independent assortment. If two different traits were always transmitted together as unit, it ...
... Note: smooth pods are the same as inflated pods. C11. The genotypes are 1 YY : 2 Yy : 1 yy. The phenotypes are 3 yellow : 1 green. C12. Offspring with a nonparental phenotype are consistent with the idea of independent assortment. If two different traits were always transmitted together as unit, it ...
Rapid evolution in crop-weed hybrids under artificial selection for
... in homoploid hybrid lineages in both plants (Hegarty and Hiscock 2005) and animals (Mallet 2007). In general, evidence for new lineages has been inferred from the geographic occurrence of hybrid zones. The use of experimental hybridization and artificial selection to speed up natural processes allow ...
... in homoploid hybrid lineages in both plants (Hegarty and Hiscock 2005) and animals (Mallet 2007). In general, evidence for new lineages has been inferred from the geographic occurrence of hybrid zones. The use of experimental hybridization and artificial selection to speed up natural processes allow ...
Genotyping errors - Proceedings of the Royal Society B
... The mean error rate per AFLP phenotype was 0.85%, a value within the range reported in other studies (Pompanon et al. 2005). However, two samples accounted for 46% of all errors. Clearly, the replicate for these samples did not amplify well and were thus excluded from subsequent analyses. Error rate ...
... The mean error rate per AFLP phenotype was 0.85%, a value within the range reported in other studies (Pompanon et al. 2005). However, two samples accounted for 46% of all errors. Clearly, the replicate for these samples did not amplify well and were thus excluded from subsequent analyses. Error rate ...
Document
... Note: smooth pods are the same as inflated pods. C11. The genotypes are 1 YY : 2 Yy : 1 yy. The phenotypes are 3 yellow : 1 green. C12. Offspring with a nonparental phenotype are consistent with the idea of independent assortment. If two different traits were always transmitted together as unit, it ...
... Note: smooth pods are the same as inflated pods. C11. The genotypes are 1 YY : 2 Yy : 1 yy. The phenotypes are 3 yellow : 1 green. C12. Offspring with a nonparental phenotype are consistent with the idea of independent assortment. If two different traits were always transmitted together as unit, it ...
A SNP in the ABCC11 gene is the determinant of human earwax type
... GG homozygotes at each of the three SNP loci (Table 1 and Supplementary Table 1 online). Among the SNPs, only rs17822931 is nonsynonymous (G180R); rs6500380 does not create any splicing sites nor affect splicing factor binding motifs or known promoter sequences, and ss49784070 is located within the ...
... GG homozygotes at each of the three SNP loci (Table 1 and Supplementary Table 1 online). Among the SNPs, only rs17822931 is nonsynonymous (G180R); rs6500380 does not create any splicing sites nor affect splicing factor binding motifs or known promoter sequences, and ss49784070 is located within the ...
Chapter 2: Mendelian Inheritance
... 4. Mendel’s experimental data (page 26) indicated the following: a. The F2 generation of seeds possessed a 9:3:3:1 phenotypic ratio, not the 1:2:1 ratio expected by a linked model. b. Some seeds of the F2 generation were nonparentals, thus further disproving that the traits were linked. 5. Mendel’s ...
... 4. Mendel’s experimental data (page 26) indicated the following: a. The F2 generation of seeds possessed a 9:3:3:1 phenotypic ratio, not the 1:2:1 ratio expected by a linked model. b. Some seeds of the F2 generation were nonparentals, thus further disproving that the traits were linked. 5. Mendel’s ...
Levels of inbreeding depression over seven generations of selfing in
... et al., 2001a,b), as long as inbreeding depression is not substantially ‘purged’ from populations after continued inbreeding, as could occur if inbreeding depression were caused by many recessive deleterious alleles scattered throughout the genome (Charlesworth & Charlesworth, 1987; Lande et al., 19 ...
... et al., 2001a,b), as long as inbreeding depression is not substantially ‘purged’ from populations after continued inbreeding, as could occur if inbreeding depression were caused by many recessive deleterious alleles scattered throughout the genome (Charlesworth & Charlesworth, 1987; Lande et al., 19 ...
Chapter 2: Mendelian Inheritance
... 1. Mendel was unaware of the concept of DNA or genes. a. the term gene was first introduced by Wilhelm Johannsen b. genes reside on chromosomes c. the variants in the traits are due to versions of the gene called an allele 2. Mendel’s law of segregation: The two copies of a gene segregate from each ...
... 1. Mendel was unaware of the concept of DNA or genes. a. the term gene was first introduced by Wilhelm Johannsen b. genes reside on chromosomes c. the variants in the traits are due to versions of the gene called an allele 2. Mendel’s law of segregation: The two copies of a gene segregate from each ...
Pedigree Charts
... thousand genes but few, if any, of these have anything to do directly with sex determination. The X chromosome likely contains genes that provide instructions for making proteins. These proteins perform a variety of different roles in the body. ...
... thousand genes but few, if any, of these have anything to do directly with sex determination. The X chromosome likely contains genes that provide instructions for making proteins. These proteins perform a variety of different roles in the body. ...
Considerations for Analyzing Targeted NGS Data – HLA
... High rate of polymorphism – up to 100 times the average human mutation rate. The HLA-DRB1 and HLA-B loci have the highest sequence variation rate within the human genome. High degree of heterozygosity – homozygotes are the exception in this region. ...
... High rate of polymorphism – up to 100 times the average human mutation rate. The HLA-DRB1 and HLA-B loci have the highest sequence variation rate within the human genome. High degree of heterozygosity – homozygotes are the exception in this region. ...
STB 221 THEORY - Unesco
... Recessive trait or character -this is controlled by recessive genes that can not express itself in all generations, but only in certain generations in the absence of the dominant gene. It is denoted with small letters such as tt, ss . Filial generations - these are the series of offspring produced f ...
... Recessive trait or character -this is controlled by recessive genes that can not express itself in all generations, but only in certain generations in the absence of the dominant gene. It is denoted with small letters such as tt, ss . Filial generations - these are the series of offspring produced f ...
Powerpoint show
... and disease chromosomes to establish all affected family members have mutation 6. Test expression of gene, in expected tissues? 7. Identify potential function of protein and explain its role in disease ...
... and disease chromosomes to establish all affected family members have mutation 6. Test expression of gene, in expected tissues? 7. Identify potential function of protein and explain its role in disease ...
Genetic Testing for the Diagnosis of Inherited Peripheral
... Most cases of CMT are autosomal dominant, although autosomal recessive and X-linked dominant forms exist. The majority of cases are CMT type 1 (approximately 40-50% of all CMT cases, with 78-80% of those due to PMP22 variants). CMT type 2 is associated with about 1015% of CMT cases, with 20% of thos ...
... Most cases of CMT are autosomal dominant, although autosomal recessive and X-linked dominant forms exist. The majority of cases are CMT type 1 (approximately 40-50% of all CMT cases, with 78-80% of those due to PMP22 variants). CMT type 2 is associated with about 1015% of CMT cases, with 20% of thos ...
Genetics Notes Part I - hrsbstaff.ednet.ns.ca
... For example, farmers might selectively cross-pollinate a cold-hardy wheat with one that grows quicker in order to create a new variety that can survive in Canada's colder, shorter growing season. ...
... For example, farmers might selectively cross-pollinate a cold-hardy wheat with one that grows quicker in order to create a new variety that can survive in Canada's colder, shorter growing season. ...
PART 10 - Mike South
... including a specific fluorescent in situ hybridization (FISH) test for this microdeletion, which confirmed the diagnosis. 90% of children with this condition are the first person in their family to be affected. However, 10% have inherited the condition from a parent, who may be unaware they are aff ...
... including a specific fluorescent in situ hybridization (FISH) test for this microdeletion, which confirmed the diagnosis. 90% of children with this condition are the first person in their family to be affected. However, 10% have inherited the condition from a parent, who may be unaware they are aff ...
Effects of Genic Base Composition on Growth Rate in G+C
... To date, virtually every study that has searched for the underlying basis of the compositional variation among bacteria has been retrospective, based chiefly on the relationship between genomic G+C contents and some environmental variable or molecular feature (Rocha and Feil 2010). Given the evidenc ...
... To date, virtually every study that has searched for the underlying basis of the compositional variation among bacteria has been retrospective, based chiefly on the relationship between genomic G+C contents and some environmental variable or molecular feature (Rocha and Feil 2010). Given the evidenc ...
Are you your grandmother`s favorite
... The MGM has two X-chromosomes, and so any given X-linked gene of hers has a 50 per cent chance of being transmitted to her daughter. Her daughter has one X from the MGM and one X from the maternal grandfather (‘MGF’). She will pass down one of those two X chromosomes to each child, regardless of whe ...
... The MGM has two X-chromosomes, and so any given X-linked gene of hers has a 50 per cent chance of being transmitted to her daughter. Her daughter has one X from the MGM and one X from the maternal grandfather (‘MGF’). She will pass down one of those two X chromosomes to each child, regardless of whe ...
PEDIGREE CHARTS - science8k / FrontPage
... PEDIGREE CHARTS A family history of a genetic condition ...
... PEDIGREE CHARTS A family history of a genetic condition ...
Genetic tasks V: GENE INTERACTIONS
... 12. In pumpkin, the shape is determined by two genes. Dominant allele of gene A or B determines round shape, dominant alleles of both genes determine discoid shape, while homozygous genotype aabb determines elongated shape. a) Use colours in Punnet square (or branching method) to differentiate phen ...
... 12. In pumpkin, the shape is determined by two genes. Dominant allele of gene A or B determines round shape, dominant alleles of both genes determine discoid shape, while homozygous genotype aabb determines elongated shape. a) Use colours in Punnet square (or branching method) to differentiate phen ...
The Answer Is Fifteen Percent - CHEST Journal
... risk for the development of COPD. Evidence that genetic factors are associated with the development of COPD comes from several sources. Familial clustering of COPD has been observed,3 and twin studies4 have supported the concept of a genetic predisposition to COPD. Statistical models suggest that th ...
... risk for the development of COPD. Evidence that genetic factors are associated with the development of COPD comes from several sources. Familial clustering of COPD has been observed,3 and twin studies4 have supported the concept of a genetic predisposition to COPD. Statistical models suggest that th ...
Population genetics
Population genetics is the study of the distribution and change in frequency of alleles within populations, and as such it sits firmly within the field of evolutionary biology. The main processes of evolution (natural selection, genetic drift, gene flow, mutation, and genetic recombination) form an integral part of the theory that underpins population genetics. Studies in this branch of biology examine such phenomena as adaptation, speciation, population subdivision, and population structure.Population genetics was a vital ingredient in the emergence of the modern evolutionary synthesis. Its primary founders were Sewall Wright, J. B. S. Haldane and Ronald Fisher, who also laid the foundations for the related discipline of quantitative genetics.Traditionally a highly mathematical discipline, modern population genetics encompasses theoretical, lab and field work. Computational approaches, often utilising coalescent theory, have played a central role since the 1980s.