APPROACHES TO CARBOHYDRATE-BASED CHEMICAL LIBRARIES: THE
... the most profound of these changes is a fairly new approach to drug development known as combinatorial chemistry. The goal of combinatorial chemistry is to rapidly produce large and diverse chemical libraries as sources of lead compounds and viable pharmaceuticals. Traditional approaches to drug dis ...
... the most profound of these changes is a fairly new approach to drug development known as combinatorial chemistry. The goal of combinatorial chemistry is to rapidly produce large and diverse chemical libraries as sources of lead compounds and viable pharmaceuticals. Traditional approaches to drug dis ...
Symmetry breaking and strong coupling in planar optical
... [2,3,6,16]. Such resonant modes have been termed variously as dark modes, subradiant modes or trapped modes [16]. This nomenclature suggests that dark modes do not readily radiate since they are trapped within the resonator. These modes couple weakly to the free space and needs an external perturbat ...
... [2,3,6,16]. Such resonant modes have been termed variously as dark modes, subradiant modes or trapped modes [16]. This nomenclature suggests that dark modes do not readily radiate since they are trapped within the resonator. These modes couple weakly to the free space and needs an external perturbat ...
S P E C T R O S C O... F E R R O I C S Y S...
... New applications of ferroic systems often consider domain wall as carrier of information. Understanding of the nature of domain structure and its dynamics is therefore essential. At the same time the omnipresent need of keeping up with Moore law demands the dimensions of commercialized devices to de ...
... New applications of ferroic systems often consider domain wall as carrier of information. Understanding of the nature of domain structure and its dynamics is therefore essential. At the same time the omnipresent need of keeping up with Moore law demands the dimensions of commercialized devices to de ...
INTRODUCTION ...
... radiation) interact primarily with the electrons of a sample, while neutrons interact with the nuclei. The strength of the interaction is very dependent on the particular nuclide involved, isotopes and spin states. Another difference is that the wavelength of the electromagnetic radiation used for R ...
... radiation) interact primarily with the electrons of a sample, while neutrons interact with the nuclei. The strength of the interaction is very dependent on the particular nuclide involved, isotopes and spin states. Another difference is that the wavelength of the electromagnetic radiation used for R ...
Polarization quantum beat spectroscopy of HCF„A˜1A …. II. Renner
... determined by fitting unperturbed lines in the K a ⫽0←1 and 2←1 subbands.33 Two K a ⫽1←0 subbands are clearly observed, a situation similar to that found for 2 10 , where the perturbation was assigned to the Renner–Teller interaction with a high vibrational level of X̃ 1 A ⬘ , and a coupling matrix ...
... determined by fitting unperturbed lines in the K a ⫽0←1 and 2←1 subbands.33 Two K a ⫽1←0 subbands are clearly observed, a situation similar to that found for 2 10 , where the perturbation was assigned to the Renner–Teller interaction with a high vibrational level of X̃ 1 A ⬘ , and a coupling matrix ...
Multidimensional Vibrational Spectroscopy of Hydrogen Bonds in
... acceptor atom, X and Y, between which a hydrogen atom is located: X–H· · · Y. The donor forms a covalent bond with the hydrogen atom whereas the interaction between the hydrogen atom and the acceptor is often considerably weaker∗ [1]. Despite its simplicity, the relevance of hydrogen bonds in nature ...
... acceptor atom, X and Y, between which a hydrogen atom is located: X–H· · · Y. The donor forms a covalent bond with the hydrogen atom whereas the interaction between the hydrogen atom and the acceptor is often considerably weaker∗ [1]. Despite its simplicity, the relevance of hydrogen bonds in nature ...
Polarization quantum beat spectroscopy of HCF„A˜1A …. I. 19F and
... We note that the 2 2 3 1 and 2 3 3 1 levels show a larger Zeeman effect than expected based upon the trend observed for the other levels 共Fig. 4兲. Consistent with previous work,25–28 we find, in addition to lifetime lengthening,31,33 large Zeeman 共and hyperfine兲 splittings associated with singlet-tr ...
... We note that the 2 2 3 1 and 2 3 3 1 levels show a larger Zeeman effect than expected based upon the trend observed for the other levels 共Fig. 4兲. Consistent with previous work,25–28 we find, in addition to lifetime lengthening,31,33 large Zeeman 共and hyperfine兲 splittings associated with singlet-tr ...
COURSES SCHEME & SYLLABUS
... Course Objective: To impart advanced knowledge of aromaticity, stereochemistry of organic compounds, pericyclic and photochemical reactions. Stereochemistry: Conformational analysis of Cycloalkanes and Decalins, Effect of conformation on reactivity, Conformation of sugars, Steric-strain due to unavo ...
... Course Objective: To impart advanced knowledge of aromaticity, stereochemistry of organic compounds, pericyclic and photochemical reactions. Stereochemistry: Conformational analysis of Cycloalkanes and Decalins, Effect of conformation on reactivity, Conformation of sugars, Steric-strain due to unavo ...
Coupling ultracold atoms to mechanical oscillators
... by the experimentally achievable curvature of the atomic trapping potential. While magnetic microtraps and optical lattices can reach ωa /2π ∼ 1 MHz [87, 88], ion traps have reached up to 50 MHz [89]. Finally, g0 contains the coupling strength parameter as defined in Eq. (7). In most cases, this p ...
... by the experimentally achievable curvature of the atomic trapping potential. While magnetic microtraps and optical lattices can reach ωa /2π ∼ 1 MHz [87, 88], ion traps have reached up to 50 MHz [89]. Finally, g0 contains the coupling strength parameter as defined in Eq. (7). In most cases, this p ...
Theoretical and empirical comparison of coupling coefficient and
... than a refractive index of n1 and n2. V and a are assumed to be constant, but actually they do change during fusion together with a wave number and propagation constant due to changes in fiber geometry. This description can be observed in Figure 6. Since d is proportional to κ, then increasing d at ...
... than a refractive index of n1 and n2. V and a are assumed to be constant, but actually they do change during fusion together with a wave number and propagation constant due to changes in fiber geometry. This description can be observed in Figure 6. Since d is proportional to κ, then increasing d at ...
and octa-substituted gallium and indium phthalocyanines
... phthalocyanine complexes are of fundamental importance, hence this work presents the study of these parameters. Specific phthalocyanines can thus be tailored such that they consist of certain properties which are required for various applications since the possibility of combining an unlimited number ...
... phthalocyanine complexes are of fundamental importance, hence this work presents the study of these parameters. Specific phthalocyanines can thus be tailored such that they consist of certain properties which are required for various applications since the possibility of combining an unlimited number ...
Advanced Study of Switchable Spin Crossover Compounds Gavin Craig
... temperatures, there will be a majority population of the LS state, with the HS being increasingly formed at higher temperatures. Temperature variation is in fact the most common method to switch between the spin states, although it can also be achieved through irradiation with light,18-21 the applic ...
... temperatures, there will be a majority population of the LS state, with the HS being increasingly formed at higher temperatures. Temperature variation is in fact the most common method to switch between the spin states, although it can also be achieved through irradiation with light,18-21 the applic ...
New perspectives for Rashba spin–orbit coupling
... spin-dependent distortion of electron trajectories in the presence of a SO-coupled band structure, which gives rise to the intrinsic spin Hall effect 10,11 (Box 2). In ref. 11, researchers predicted the existence of a universal spin Hall conductivity σH = eΦB/8π2 for a ballistic twodimensional elect ...
... spin-dependent distortion of electron trajectories in the presence of a SO-coupled band structure, which gives rise to the intrinsic spin Hall effect 10,11 (Box 2). In ref. 11, researchers predicted the existence of a universal spin Hall conductivity σH = eΦB/8π2 for a ballistic twodimensional elect ...
Optical Two-Dimensional Fourier Transform Spectroscopy of
... Optical two-dimensional (2D) Fourier transform spectroscopy (FTS) based on, but surpassing, traditional FWM techniques is a promising tool to address these problems. As an optical analog of multidimensional nuclear magnetic resonance (NMR) spectroscopy [8], 2D FTS has been implemented for probing th ...
... Optical two-dimensional (2D) Fourier transform spectroscopy (FTS) based on, but surpassing, traditional FWM techniques is a promising tool to address these problems. As an optical analog of multidimensional nuclear magnetic resonance (NMR) spectroscopy [8], 2D FTS has been implemented for probing th ...
HYBRID MULTIDENTATE PHOSPHINE
... Independent electron-rich σ-donor ligands could increase back-bonding from the d10 palladium(0) centre to the π-acidic dba, thus strengthening this Pd0-alkene interaction and thereby reducing the overall concentration of the active Pd0Ln species. The incorporation of an electron-withdrawing substitu ...
... Independent electron-rich σ-donor ligands could increase back-bonding from the d10 palladium(0) centre to the π-acidic dba, thus strengthening this Pd0-alkene interaction and thereby reducing the overall concentration of the active Pd0Ln species. The incorporation of an electron-withdrawing substitu ...
NMR studies of the amyloid β -peptide
... proteins. Proteins are polypeptide chains constructed from a pool of twenty different amino acids, each of which has its own specific characteristic properties. The function of a protein is closely related to the three dimensional structure. This relationship may look different for different protein ...
... proteins. Proteins are polypeptide chains constructed from a pool of twenty different amino acids, each of which has its own specific characteristic properties. The function of a protein is closely related to the three dimensional structure. This relationship may look different for different protein ...
Tuning the Molecular Properties of Polybenzimidazole by
... solutions in H2SO4 (98%) were carried out at 30 °C in a constant temperature water bath, using a Cannon Ubbelohde capillary dilution viscometer (model F725), and the inherent viscosity (IV) values were calculated from the flow time data. For all the flow time measurements 0.2 g/dL of polymer solutio ...
... solutions in H2SO4 (98%) were carried out at 30 °C in a constant temperature water bath, using a Cannon Ubbelohde capillary dilution viscometer (model F725), and the inherent viscosity (IV) values were calculated from the flow time data. For all the flow time measurements 0.2 g/dL of polymer solutio ...
Correlated/non-correlated ion dynamics of charge
... employing static high field approaches that probe fast motions.9–11 Our interest in this particular salt, which possesses limited stability under certain conditions,12 arises solely from the ionic symmetries provided, which are otherwise unavailable with other salts. The protic cation provides a bul ...
... employing static high field approaches that probe fast motions.9–11 Our interest in this particular salt, which possesses limited stability under certain conditions,12 arises solely from the ionic symmetries provided, which are otherwise unavailable with other salts. The protic cation provides a bul ...
PREPARATION, STRUCTURAL STUDIES AND CHEMICAL
... Compounds with hypervalent iodine and oxygen atoms incorporated in the same five membered ring (4-6) are known as benziodoxoles. They are the most important and widely used hypervalent iodine reagents for various chemical reactions.25 The IBX 5 and DMP 6 are employed as good oxidizing agents, especi ...
... Compounds with hypervalent iodine and oxygen atoms incorporated in the same five membered ring (4-6) are known as benziodoxoles. They are the most important and widely used hypervalent iodine reagents for various chemical reactions.25 The IBX 5 and DMP 6 are employed as good oxidizing agents, especi ...
PDF w - ACS Publications - American Chemical Society
... relative to their BDEs. This finding suggests that there are other factors in addition to the BDE of the C−H bond influencing the rate constant of the reaction. For example, a mechanistic study of HAT by an iron(III) imido complex revealed a strong dependence of the rate constants on the size and ster ...
... relative to their BDEs. This finding suggests that there are other factors in addition to the BDE of the C−H bond influencing the rate constant of the reaction. For example, a mechanistic study of HAT by an iron(III) imido complex revealed a strong dependence of the rate constants on the size and ster ...
MEMBRANE PROTEIN STRUCTURE AND DYNAMICS STUDIED
... made in the development of spectrometers and applicable methods. Such advances are also accompanied by novel chemistry approaches to design probes fulfilling desirable requirements in terms of incorporation into proteins, labeling efficiency, similarity with natural amino acid side chains, negligibl ...
... made in the development of spectrometers and applicable methods. Such advances are also accompanied by novel chemistry approaches to design probes fulfilling desirable requirements in terms of incorporation into proteins, labeling efficiency, similarity with natural amino acid side chains, negligibl ...
Electron spin resonance (ESR) spectroscopy of low
... rubbed with it [10]. The rst known application of magnetism is the compass, introduced by the Chinese, mainly for terrestrial navigation as it took until the end of the 12th century to appear also on ships [11]. Although it was well known that magnets only attract iron and iron rich metals, it was ...
... rubbed with it [10]. The rst known application of magnetism is the compass, introduced by the Chinese, mainly for terrestrial navigation as it took until the end of the 12th century to appear also on ships [11]. Although it was well known that magnets only attract iron and iron rich metals, it was ...
syllabus for two‐year four‐semester course in chemistry 2014
... Spectrophotometric, ion exchange and complexometric estimations. Identification of single organic liquid with one or more functional groups. Numerical, kinetic and equilibrium experiments. ...
... Spectrophotometric, ion exchange and complexometric estimations. Identification of single organic liquid with one or more functional groups. Numerical, kinetic and equilibrium experiments. ...
L-edge X-ray absorption study of mononuclear vanadium complexes
... spectral region is dominated by 1s - np dipole (and quadrupole) transitions, whereas the L2,3 spectral region mainly corresponds to transitions between the 2p-core orbitals and partially filled or empty nd-based orbitals. Being dominantly based on electric dipole allowed transitions into the metal d ...
... spectral region is dominated by 1s - np dipole (and quadrupole) transitions, whereas the L2,3 spectral region mainly corresponds to transitions between the 2p-core orbitals and partially filled or empty nd-based orbitals. Being dominantly based on electric dipole allowed transitions into the metal d ...
Chemical Shift and Electric Field Gradient
... taking the average with the second one. This procedure cancels part of the error originating from imperfect crystal orientation. The QC tensors of the carboxyl deuterons were determined in analogy to those of the amide deuterons from the carboxyl data shown in Figure 4. Again the QC tensor listed in ...
... taking the average with the second one. This procedure cancels part of the error originating from imperfect crystal orientation. The QC tensors of the carboxyl deuterons were determined in analogy to those of the amide deuterons from the carboxyl data shown in Figure 4. Again the QC tensor listed in ...
Nuclear magnetic resonance spectroscopy
Nuclear magnetic resonance spectroscopy, most commonly known as NMR spectroscopy, is a research technique that exploits the magnetic properties of certain atomic nuclei. It determines the physical and chemical properties of atoms or the molecules in which they are contained. It relies on the phenomenon of nuclear magnetic resonance and can provide detailed information about the structure, dynamics, reaction state, and chemical environment of molecules. The intramolecular magnetic field around an atom in a molecule changes the resonance frequency, thus giving access to details of the electronic structure of a molecule.Most frequently, NMR spectroscopy is used by chemists and biochemists to investigate the properties of organic molecules, although it is applicable to any kind of sample that contains nuclei possessing spin. Suitable samples range from small compounds analyzed with 1-dimensional proton or carbon-13 NMR spectroscopy to large proteins or nucleic acids using 3 or 4-dimensional techniques. The impact of NMR spectroscopy on the sciences has been substantial because of the range of information and the diversity of samples, including solutions and solids.NMR spectra are unique, well-resolved, analytically tractable and often highly predictable for small molecules. Thus, in organic chemistry practice, NMR analysis is used to confirm the identity of a substance. Different functional groups are obviously distinguishable, and identical functional groups with differing neighboring substituents still give distinguishable signals. NMR has largely replaced traditional wet chemistry tests such as color reagents for identification. A disadvantage is that a relatively large amount, 2–50 mg, of a purified substance is required, although it may be recovered. Preferably, the sample should be dissolved in a solvent, because NMR analysis of solids requires a dedicated MAS machine and may not give equally well-resolved spectra. The timescale of NMR is relatively long, and thus it is not suitable for observing fast phenomena, producing only an averaged spectrum. Although large amounts of impurities do show on an NMR spectrum, better methods exist for detecting impurities, as NMR is inherently not very sensitive.NMR spectrometers are relatively expensive; universities usually have them, but they are less common in private companies. Modern NMR spectrometers have a very strong, large and expensive liquid helium-cooled superconducting magnet, because resolution directly depends on magnetic field strength. Less expensive machines using permanent magnets and lower resolution are also available, which still give sufficient performance for certain application such as reaction monitoring and quick checking of samples. There are even benchtop NMR spectrometers.