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L1 Nephritis 2013
L1 Nephritis 2013

... Type I MPGN (80% of cases) - Circulating immune complexes have been identified - May occur in association with hepatitis B&C antigenemia, extra-renal infections or SLE - Characterized by subendothelial and mesangial deposits - Activation of complement by classical pathway ...
Current progress in beta-amyloid immunotherapy
Current progress in beta-amyloid immunotherapy

... After immunization with Ab, the peptide is processed by antigen-presenting cells in the periphery and then presented to T and B cells. Epitope mapping of these events following Ab immunization in AD patients indicates that the predominance of T-cell epitopes lies in the central to carboxy-terminal r ...
2-Pathology of non-atherosclerotic vascular diseases_1
2-Pathology of non-atherosclerotic vascular diseases_1

... diagnostic markers and their levels may reflect the degree of inflammatory activity ...
rheumatoid arthritis
rheumatoid arthritis

...  Rheumatoid factor — An antibody is present in the blood of 70 to 80 percent of people with RA.  RF is not specific for RA but is also present in other connective tissue diseases, infections, and autoimmune disorders, as well as in 1-5% of healthy people.  The presence of RF predicts radiographic ...
Bullous Pemphigoid
Bullous Pemphigoid

... requires high doses of cortisone (‘steroids’) taken internally. Severe bullous pemphigoid can also require immune-suppression drugs such as azathioprine . Tetracycline has been used as a treatment option. Other treatments that have been used for severe disease include intravenous immunoglobulin infu ...
PPT - Larry Smarr - California Institute for Telecommunications and
PPT - Larry Smarr - California Institute for Telecommunications and

... Next Decade Will See New Microbiome “Gardening Tools” ...
probiotics (vsl#3)
probiotics (vsl#3)

... been described for decades, though the mechanisms by which they exert these beneficial effects remain to be elucidated (27). Cross-talk between bacteria and between bacteria and antigen-presenting cells of the intestine seem to play an important role in controlling overgrowth of potentially pathogen ...
The Immune System in Occupational Disease
The Immune System in Occupational Disease

... inflammation or chronic inflammation/pathology • Immune mediators (i.e. cytokines) are responsible for redness, swelling, heat & pain • Inflammation consists of immune cells infiltrating an organ/tissue • Inflammation is closely intertwined with the process of repair • Inflammation & repair can both ...
The First 100 Hospitalized Severe Complicated Influenza Cases
The First 100 Hospitalized Severe Complicated Influenza Cases

... time between onset of symptoms and first doctor visit was 1 day, and the median hospital stay for those who had been discharged was 6 days. The average duration from onset of symptoms to the date of rapid testing, admission, or prescription of oseltamivir for patients with onset after August 15 was ...
Zonulin! The Wheat Conundrum Solved (Well, Mostly …)
Zonulin! The Wheat Conundrum Solved (Well, Mostly …)

... gliadin susceptibility, breastfed babies have a decreased risk of developing celiac disease.11,12 This protection is more complete when infants continue to be breastfed after dietary gluten is introduced. The risk of celiac disease is greater when gluten was introduced in the diet in large amounts t ...
SDL 9- Rheumatic Heart Disease and Rheumatic Fever Acute
SDL 9- Rheumatic Heart Disease and Rheumatic Fever Acute

... Delayed manifestation—2-3 weeks after disease onset last for just a few days—associated with carditis Histologically: fibrinoid necrosis in center of nodule (swollen, eosiniophilic collagen fibers) surrounded by lymphocytes, plasma cells, and macrophages Other features: fever (>39C), elevated acute ...
Elevated serum anti-flagellin antibodies implicate
Elevated serum anti-flagellin antibodies implicate

... Introduction: Ankylosing spondylitis (AS) and inflammatory bowel disease (IBD) share genetic and clinical features. IBD is associated with the presence of antibodies to a variety of commensal microorganisms including anti-Saccharomyces cerevesiae antibodies (ASCA), antineutrophil cytoplasmic antibod ...
Organ-preserving treatment of an epididymal abscess in a patient
Organ-preserving treatment of an epididymal abscess in a patient

... adjunctive homeopathic treatment, local findings improved and infection parameters returned to normal. The quick amelioration of both the clinical symptoms and the sonographic findings demonstrated that homeopathic treatment might have significantly aided in the recovery. We used classical homeopath ...
Paraneoplastic Cerebellar Degeneration
Paraneoplastic Cerebellar Degeneration

... To aid in the diagnosis, any possible imaging studies such as CT, MRI and PET would be useful and could help find the primary tumor in patients with these disorders. Histology of the patients found with paraneoplastic syndromes has not been determined. No certain race or sex seems to be affected mor ...
In Focus Autoantibodies in anti-neutrophil cytoplasm antibody
In Focus Autoantibodies in anti-neutrophil cytoplasm antibody

... why disease activity and ANCA titre can dissociate—as it appears that anti-moesin antibodies can persist during remission at similar titres to those in acute disease. There is a gathering consensus that patients with AAV should be stratified according to whether they have antibodies to MPO or PR3 [9, ...
Glomerular Diseases
Glomerular Diseases

... Based on EM,IF & pathogenesis 3 types: Type-1: Comprises > 70 % cases. Classic form. Immune complex disease. • Immune deposits in subendothelial space • Seen in association with SLE, Sjogrens, ...
Afzali Mini Medical IBD
Afzali Mini Medical IBD

... Understanding your immune system Current treatments in IBD Newer therapies in IBD ...
OIE listed Diseases Notification
OIE listed Diseases Notification

... • For diseases listed under this article, a disease-specific Aquatic Code chapter provide standards for safe international trade • Article 1.2.3 – Criteria for listing an emerging aquatic animal disease • For diseases listed under this article, there is no disease-specific Aquatic Code chapter and t ...
Theileria parva infections
Theileria parva infections

... eradicated in a prolonged campaign consisting of movement control, tick control, destocking of infected pastures, and slaughter. The disease has persisted in the region north of the Zambezi River to the present day and is a major constraint on the development of cattle production. Corridor disease c ...
European Respiratory Society Annual Congress 2012
European Respiratory Society Annual Congress 2012

... Pulmonary Disease (COPD) has been associated with increase risk of CAP. Most recently, ICS have been associated with less severity of CAP and decreased risk of pneumonia-related mortality. Pleural infection is a frequent complication of CAP that may increase mortality. The aim of this study was to a ...
Document
Document

...  Uncertain — CD – prob ok to stop after 4 years — UC – v.likely to relapse (esp if ↑CRP, ↓Hb, non-smoker)  Wean slowly if need to stop ...
Table 6-11. Calculating a Life Table
Table 6-11. Calculating a Life Table

... We found that a cohort of patients with lung cancer first treated in 1977 had higher six-month survival rates for the total group and for subgroups in each of the three main TNM stages (tumor, nodes, and metastases) than a cohort treated between 1953 and 1964 at the same institutions. The more recen ...
Trichuris suis Seems to Be Safe and Possibly
Trichuris suis Seems to Be Safe and Possibly

... Patients were excluded if they had had cancer of any type, a history of alcohol or drug abuse, stools positive for pathogens, ova, or parasites, Clostridium difficile (C. difficile) toxin, or a significant and concurrent systemic infection such as hepatitis B virus, hepatitis C virus, or HIV. They w ...
Rheumatoid Arthritis by Dr Sarma
Rheumatoid Arthritis by Dr Sarma

... MTX is given 10 to 30 mg orally, IM, or SC per week It is DHF reductase inhibitor – Supplemental folic acid The clinical improvement takes one to two months Nausea, diarrhea; mouth ulcers; rash, alopecia; Abnormal LFT Rare: low WBC & platelets; pneumonitis; sepsis; liver disease; EBV related lymphom ...
Document
Document

... (FPA) is that extra precautions should be taken for at least 4 weeks, and there should be no break between courses of tablets (inactive tablets should be omitted). Avoid drinking alcohol while on the drug Headache, feeling sick and/or stomach pain may occur while on the drug. Please contact your doc ...
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Neuromyelitis optica

Neuromyelitis optica (NMO), also known as Devic's disease or Devic's syndrome, is a heterogeneous condition consisting of the simultaneous inflammation and demyelination of the optic nerve (optic neuritis) and the spinal cord (myelitis). It can be monophasic or recurrent.Currently at least two different causes are proposed based on the presence of autoantibodies against AQP4. AQP4+ NMO is currently considered an autoimmune disease (autoimmune astrocytopathy, or autoimmune astrocytic channelopathy) in which a person's own immune system attacks the astrocytes of the optic nerves and spinal cord. The cause of the AQP4- variants is unknown.Although inflammation may also affect the brain, the lesions are different from those observed in the related condition, multiple sclerosis. Spinal cord lesions lead to varying degrees of weakness or paralysis in the legs or arms, loss of sensation (including blindness), and/or bladder and bowel dysfunction.Devic's disease is now studied along a collection of similar diseases called ""Neuromyelitis optica spectrum diseases"". Some cases of this spectrum resemble multiple sclerosis (MS) in several ways, but require a different course of treatment for optimal results.In 2004, NMO-IgG (currently known as Anti-AQP IgG) was first described leading to the distinction between positive and negative cases.In Anti-AQP positive variants, CNS astrocytes, which are the basis for the glymphatic system are the target of the autoimmune attack. NMO-IgG-negative cases are less understood. It seems currently that astrocytes are spared in these IgG negative cases
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