The Proteome of Native Adult Müller Glial Cells From Murine
... For many years, research on retinal diseases mainly concentrated on investigations of functional deficits of retinal neurons. Müller cells, the dominant macroglia cells of the retina, were considered passive bystanders. However, owing to their distinct morphology spanning the whole thickness of the ...
... For many years, research on retinal diseases mainly concentrated on investigations of functional deficits of retinal neurons. Müller cells, the dominant macroglia cells of the retina, were considered passive bystanders. However, owing to their distinct morphology spanning the whole thickness of the ...
CD95 ligation and intracellular membrane flow
... cross-talk between endosomal and mitochondrial compartments was accompanied by a loss of the MMP and apoptosis execution. This cell remodelling was sensitive to monensin and was absent not only after induction of receptor-independent cell death with staurosporine, but also in cells selected for mult ...
... cross-talk between endosomal and mitochondrial compartments was accompanied by a loss of the MMP and apoptosis execution. This cell remodelling was sensitive to monensin and was absent not only after induction of receptor-independent cell death with staurosporine, but also in cells selected for mult ...
What is the endocrine system?
... to stay healthy. This system has special organs called glands that produce chemicals called hormones. Hormones are also called chemical messengers, because they move through your blood, delivering chemical information to different parts of your body. The endocrine system has four main functions: reg ...
... to stay healthy. This system has special organs called glands that produce chemicals called hormones. Hormones are also called chemical messengers, because they move through your blood, delivering chemical information to different parts of your body. The endocrine system has four main functions: reg ...
... In animals, control and coordination occur with the help of nervous system. However, plants do not have a nervous system. Plants respond to stimuli by showing movements. The growth, development, and responses to the environment in plants is controlled and coordinated by a special class of chemical s ...
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... • Find genes that are expressed in specific brain areas. • Design DNA constructs that will be integrated under the same promoter. ...
... • Find genes that are expressed in specific brain areas. • Design DNA constructs that will be integrated under the same promoter. ...
protein - Portal UniMAP
... Its primary structure mainly consists of the amino acid sequence (Gly-Ser-Gly-Ala-GlyAla)n ...
... Its primary structure mainly consists of the amino acid sequence (Gly-Ser-Gly-Ala-GlyAla)n ...
What sort of Science is Glycoscience?
... covered with dense & complex layer of glycans. • Even enveloped viruses that bud from surfaces of infected cells carry with them the glycosylation patterns of the host cell. • Most secreted molecules are glycosylated, and extracellular matrices of multicellular organisms are rich in glycans • Biofil ...
... covered with dense & complex layer of glycans. • Even enveloped viruses that bud from surfaces of infected cells carry with them the glycosylation patterns of the host cell. • Most secreted molecules are glycosylated, and extracellular matrices of multicellular organisms are rich in glycans • Biofil ...
Gene Structure, Promoter Activity, and
... cells (K562 and CCRF-CEM, respectively) revealed similar transcription rates. Therefore, ...
... cells (K562 and CCRF-CEM, respectively) revealed similar transcription rates. Therefore, ...
Chapter 7 Test A
... a. Eukaryotes were the first types of cells to exist. b. Chloroplasts arose when photosynthetic prokaryotes were engulfed by a larger cell but were not digested. c. Cells cannot exist without a nucleus to contain their DNA. d. All cells have a cell membrane, cytoplasm, ribosomes, and DNA. 15. Chloro ...
... a. Eukaryotes were the first types of cells to exist. b. Chloroplasts arose when photosynthetic prokaryotes were engulfed by a larger cell but were not digested. c. Cells cannot exist without a nucleus to contain their DNA. d. All cells have a cell membrane, cytoplasm, ribosomes, and DNA. 15. Chloro ...
Tying rings for sex
... The cyclization is catalyzed by the essential plasmidborne transfer protein, TraF, which has sequence similarity to signal peptidases [18]. TraF homologues have been shown to belong to a special class of serine proteases [20]: their catalytic activity results from serine–lysine dyad formation. Mutat ...
... The cyclization is catalyzed by the essential plasmidborne transfer protein, TraF, which has sequence similarity to signal peptidases [18]. TraF homologues have been shown to belong to a special class of serine proteases [20]: their catalytic activity results from serine–lysine dyad formation. Mutat ...
Cell injury
... follow cell death in a living tissue. The morphological changes in necrosis result from two processes :1 : enzymatic digestion of the cell either by its own enzyme (autolysis) or the cell digest by proteolytic enzyme secreted from inflammatory cell infiltrate & this is called (heterolysis) 2 : denat ...
... follow cell death in a living tissue. The morphological changes in necrosis result from two processes :1 : enzymatic digestion of the cell either by its own enzyme (autolysis) or the cell digest by proteolytic enzyme secreted from inflammatory cell infiltrate & this is called (heterolysis) 2 : denat ...
Cell cycle: The bacterial approach to coordination
... than that of wild-type cells and indicates that, while there are clearly other mechanisms contributing to the fidelity of chromosome partitioning, Spo0J plays an important role. In C. crescentus, by contrast, the parA and parB homologues are essential, but their overexpression causes defects in chro ...
... than that of wild-type cells and indicates that, while there are clearly other mechanisms contributing to the fidelity of chromosome partitioning, Spo0J plays an important role. In C. crescentus, by contrast, the parA and parB homologues are essential, but their overexpression causes defects in chro ...
Investigation 1 - cloudfront.net
... 1) Describe the shape and size of the frog blood cell. ___________________________ 2) Describe the shape and size of the human blood cell on the same magnification as the frog blood cell._________________________________________________________ 3) Are there any structures visible in one type of bloo ...
... 1) Describe the shape and size of the frog blood cell. ___________________________ 2) Describe the shape and size of the human blood cell on the same magnification as the frog blood cell._________________________________________________________ 3) Are there any structures visible in one type of bloo ...
Cellular Internalization of Fluorescent Proteins via Arginine
... layer between two outer hydrophilic surface in the membranes of plant cells to serve as a screening barrier for transport of materials across the biomembranes. Only specific biomolecules and ions may pass through via specific transporters or protein channels. Therefore, highly basic and hydrophilic ...
... layer between two outer hydrophilic surface in the membranes of plant cells to serve as a screening barrier for transport of materials across the biomembranes. Only specific biomolecules and ions may pass through via specific transporters or protein channels. Therefore, highly basic and hydrophilic ...
Structure and function of the chloroplast signal recognition particle
... therefore posed the question which structural characteristics of the LHCPs determine the transit complex formation with cpSRP. By analogy, with the co-translational targeting system where binding of cytosolic SRP54 to a substrate protein is mediated via its hydrophobic signal sequence, it was shown ...
... therefore posed the question which structural characteristics of the LHCPs determine the transit complex formation with cpSRP. By analogy, with the co-translational targeting system where binding of cytosolic SRP54 to a substrate protein is mediated via its hydrophobic signal sequence, it was shown ...
Dr Asmat Salim MM707-electrophoresis 2014
... and will move if electric field is applied. In electrophoresis, macromolecules are characterized by their rate of movement in an electric field. This technique is used to (1) distinguish molecules on the basis of charge and shape (2) to determine molecular weight of proteins (3) to detect amino a ...
... and will move if electric field is applied. In electrophoresis, macromolecules are characterized by their rate of movement in an electric field. This technique is used to (1) distinguish molecules on the basis of charge and shape (2) to determine molecular weight of proteins (3) to detect amino a ...
Haemoglobin: International Journal for Haemoglobin Research
... One of the major advances to be found in the work presented is a substantial increase in our understanding of the roles of actin in the cell; as Professor Perry aptly said in the closing remarks at the end of the Symposium ‘actin epitomizes the meeting to me’. Evidence to date suggests that the acti ...
... One of the major advances to be found in the work presented is a substantial increase in our understanding of the roles of actin in the cell; as Professor Perry aptly said in the closing remarks at the end of the Symposium ‘actin epitomizes the meeting to me’. Evidence to date suggests that the acti ...
Muscles
... Rigor mortis is a recognizable sign of death (L. mors, mortis, f.) that is caused by a chemical change in the muscles, causing the limbs of the corpse to become stiff (L. rigor, oris, m.) and difficult to move or manipulate. Assuming mild temperatures, rigor usually sets in about 3-4 hours after cli ...
... Rigor mortis is a recognizable sign of death (L. mors, mortis, f.) that is caused by a chemical change in the muscles, causing the limbs of the corpse to become stiff (L. rigor, oris, m.) and difficult to move or manipulate. Assuming mild temperatures, rigor usually sets in about 3-4 hours after cli ...
Cells
... What is a cell? • The cell is the smallest unit of life. • Cells are too small to see except under a microscope. • All living things are made up of cells. • Some living things consist of just one cell like bacteria. • Others, such as tiny pond plants and animals may contain several hundred. • Large ...
... What is a cell? • The cell is the smallest unit of life. • Cells are too small to see except under a microscope. • All living things are made up of cells. • Some living things consist of just one cell like bacteria. • Others, such as tiny pond plants and animals may contain several hundred. • Large ...
the Adult Drosophila Fat Body
... The normal and mutant strains hetero-, homo-, hemizygous for the female sterile mutantfi(1)l163 used for these experiments are described in Table I and in Bownes and Hodson (1980), Lindsley and Zimm (1985, 1986, 1987, 1990), Saunders and Bownes (1986), and Williams et al. (1987). The Oregon-R female ...
... The normal and mutant strains hetero-, homo-, hemizygous for the female sterile mutantfi(1)l163 used for these experiments are described in Table I and in Bownes and Hodson (1980), Lindsley and Zimm (1985, 1986, 1987, 1990), Saunders and Bownes (1986), and Williams et al. (1987). The Oregon-R female ...
Web Tutorial 2.3: Cell Cycle Regulation
... The cell cycle is summarized by these diagrams, which give the basic divisions of the cell cycle, some typical times spent in each stage of the cycle, and the most important checkpoints in the cycle. ...
... The cell cycle is summarized by these diagrams, which give the basic divisions of the cell cycle, some typical times spent in each stage of the cycle, and the most important checkpoints in the cycle. ...
Human Pluripotent Stem Cell-derived Articular Chondrocytes
... Introduction: Osteoarthritis (OA) is a progressively debilitating disease that primarily affects the articular cartilage of synovial joints. Cell and/or cartilage replacement is a promising therapy for OA, provided that there is access to appropriate tissue and/or sufficient numbers of articular cho ...
... Introduction: Osteoarthritis (OA) is a progressively debilitating disease that primarily affects the articular cartilage of synovial joints. Cell and/or cartilage replacement is a promising therapy for OA, provided that there is access to appropriate tissue and/or sufficient numbers of articular cho ...
Structural biology and drug design
... 1. Not more than 5 hydrogen bond donors 2. Not more than 10 hydrogen bond acceptors 3. A molecular mass below 500 Dalton (g/mol) 4. An octanol-water partition-coefficient logP not greater than 5 • These rules ensures that the compound is not too soluble and polar, so that it can cross biological mem ...
... 1. Not more than 5 hydrogen bond donors 2. Not more than 10 hydrogen bond acceptors 3. A molecular mass below 500 Dalton (g/mol) 4. An octanol-water partition-coefficient logP not greater than 5 • These rules ensures that the compound is not too soluble and polar, so that it can cross biological mem ...
Contribution of calcium-conducting channels to the transport of
... exerting regulatory functions. It is now regarded as a second messenger [63] able to influence the activity of various enzymes and to control intracellular signaling pathways [52]. Its extracellular concentration is also not constant. Several types of cells have the property to release Zn into the e ...
... exerting regulatory functions. It is now regarded as a second messenger [63] able to influence the activity of various enzymes and to control intracellular signaling pathways [52]. Its extracellular concentration is also not constant. Several types of cells have the property to release Zn into the e ...
Osmosis
... ONLY WATER – Water is a small but extremely important molecule that makes up most of the liquid part of the cytoplasm in living things. – Deals ONLY with the diffusion of WATER – The molecules (in this case, water - not solute molecules) will tend to move from an area of high (water) concentration ...
... ONLY WATER – Water is a small but extremely important molecule that makes up most of the liquid part of the cytoplasm in living things. – Deals ONLY with the diffusion of WATER – The molecules (in this case, water - not solute molecules) will tend to move from an area of high (water) concentration ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.