Evolutionary Rate in the Protein Interaction Network
... Interactions could reduce evolutionary rate in two distinct ways (Fig. 2). First, if different interactions depend on different sites, proteins with more interactors could evolve more slowly because a greater proportion of the protein is involved in protein functions (Fig. 2, arrow a). Alternatively ...
... Interactions could reduce evolutionary rate in two distinct ways (Fig. 2). First, if different interactions depend on different sites, proteins with more interactors could evolve more slowly because a greater proportion of the protein is involved in protein functions (Fig. 2, arrow a). Alternatively ...
Microbial Cell Factories
... pathways from which novel bio-products, including nano- or micro-structured materials [3537], offer promises in even more diverse applications. Still, many substances and materials of industrial interest are nowadays produced by chemical synthesis, and the number of (recombinant) proteins approved f ...
... pathways from which novel bio-products, including nano- or micro-structured materials [3537], offer promises in even more diverse applications. Still, many substances and materials of industrial interest are nowadays produced by chemical synthesis, and the number of (recombinant) proteins approved f ...
Jason Pitt - University of Evansville Faculty Web sites
... Formation of gross body structures is an easily seen outcome of apoptosis, but there are also many unseen systems that are “sculpted” by apoptosis. During prenatal development, the lungs do not serve as the major hub of gas exchange as in adults. There is a major rearrangement in the lungs necessary ...
... Formation of gross body structures is an easily seen outcome of apoptosis, but there are also many unseen systems that are “sculpted” by apoptosis. During prenatal development, the lungs do not serve as the major hub of gas exchange as in adults. There is a major rearrangement in the lungs necessary ...
ARVO 2017 Annual Meeting Abstracts 231 RPE metabolism
... Vimentin immuno-staining, suggesting that these morphologic changes are due to epithelial-mesenchymal transition EMT (Fig1). The Pink1KD cells exhibited increased mitochondrial superoxide and lactate levels, decreased (ΔΨ) and ATP production - all of which were ameliorated by Nrf2KD. Seahorse data r ...
... Vimentin immuno-staining, suggesting that these morphologic changes are due to epithelial-mesenchymal transition EMT (Fig1). The Pink1KD cells exhibited increased mitochondrial superoxide and lactate levels, decreased (ΔΨ) and ATP production - all of which were ameliorated by Nrf2KD. Seahorse data r ...
The Plastidial 2-C-Methyl-D-Erythritol 4-Phosphate
... Ziegelhoffer et al., 2000). Both farnesylated and geranylgeranylated proteins are involved in abscisic acid (ABA) signaling. The existence of farnesylated negative regulators of ABA signaling is inferred from the ABA hypersensitive phenotype of ENHANCED RESPONSE TO ABA1 (ERA1) mutants of Arabidopsis ...
... Ziegelhoffer et al., 2000). Both farnesylated and geranylgeranylated proteins are involved in abscisic acid (ABA) signaling. The existence of farnesylated negative regulators of ABA signaling is inferred from the ABA hypersensitive phenotype of ENHANCED RESPONSE TO ABA1 (ERA1) mutants of Arabidopsis ...
Curriculum Vitae - Purdue Department of Biological Sciences
... Microsequencing of the purified protein identified it as a pectin methyl esterase (PME) that binds P30 and, thus, may function as a specific P30 receptor during viral cell-to-cell movement. Supporting this idea, our results demonstrate that P30-PME interaction involves P30 domains required for its f ...
... Microsequencing of the purified protein identified it as a pectin methyl esterase (PME) that binds P30 and, thus, may function as a specific P30 receptor during viral cell-to-cell movement. Supporting this idea, our results demonstrate that P30-PME interaction involves P30 domains required for its f ...
NPSN11 Is a Cell Plate-Associated SNARE
... mammalian VTI1b group of SNAREs, although they share only a low level of homology (Fig. 1). On the other hand, other putative Arabidopsis SNARE families, such as the MEMBRIN- or GOS1-like groups, share branches with their likely orthologs (Fig. 1; for further discussion, see Sanderfoot et al., 2000) ...
... mammalian VTI1b group of SNAREs, although they share only a low level of homology (Fig. 1). On the other hand, other putative Arabidopsis SNARE families, such as the MEMBRIN- or GOS1-like groups, share branches with their likely orthologs (Fig. 1; for further discussion, see Sanderfoot et al., 2000) ...
system to Yeast as a model system to study aging mechanisms
... multiple metabolic and signal transduction pathways are similar ...
... multiple metabolic and signal transduction pathways are similar ...
Changes of cellular redox homeostasis and protein - LINK
... Chaperones are conserved and abundant proteins of the cell. They not only help to fold the newly synthesized proteins to get their final structure, but are also involved in many other events of the cellular life, such as signal transduction or protein degradation. A subset of chaperones takes part i ...
... Chaperones are conserved and abundant proteins of the cell. They not only help to fold the newly synthesized proteins to get their final structure, but are also involved in many other events of the cellular life, such as signal transduction or protein degradation. A subset of chaperones takes part i ...
IONIC BASES OF THE RESTING MEMBRANE POTENTIAL
... takes place during development. As a whole these surface glycoproteins are called the glycocalyx and account for the fact that the thickness of the cell membrane is about twice what we calculated on the basis of capacitance. b. Intrinsic proteins The intrinsic proteins are buried or interposed withi ...
... takes place during development. As a whole these surface glycoproteins are called the glycocalyx and account for the fact that the thickness of the cell membrane is about twice what we calculated on the basis of capacitance. b. Intrinsic proteins The intrinsic proteins are buried or interposed withi ...
PMD 14. Neurophys I
... extreme: mechanical, thermal, & chemical; tissue damage is involved • labeled line principle: sensory modality is not a property of a receptor, but is determined by destination in sensory areas of brain, e.g., touch is experienced because receptor stimulates sensory fiber to tactile area of brain PM ...
... extreme: mechanical, thermal, & chemical; tissue damage is involved • labeled line principle: sensory modality is not a property of a receptor, but is determined by destination in sensory areas of brain, e.g., touch is experienced because receptor stimulates sensory fiber to tactile area of brain PM ...
File
... Mitochondria release energy by combining sugar molecules with oxygen molecules to form carbon dioxide and ...
... Mitochondria release energy by combining sugar molecules with oxygen molecules to form carbon dioxide and ...
Regulation of blood glucose
... influx of calcium ions into the cell. These ions then bind to vesicles within the cell which carry the insulin hormones. The calcium causes the vesicles to move to the cell surface membrane, and undergo exocytosis: the vesicle fuses with the membrane and the insulin is released out of the cell, and ...
... influx of calcium ions into the cell. These ions then bind to vesicles within the cell which carry the insulin hormones. The calcium causes the vesicles to move to the cell surface membrane, and undergo exocytosis: the vesicle fuses with the membrane and the insulin is released out of the cell, and ...
The heterochronic gene lin-29 encodes a zinc finger protein that
... indicating that they represent lin-29 transcripts. The lin-29 cDNAs detected two poly(A+) transcripts of 2.4 and 1.8 kb in RNA blot experiments (lin-29A and lin-29B, respectively; Fig. 3A). Additional blots hybridized with radiolabeled strand-specific probes indicate these two lin-29 transcripts are ...
... indicating that they represent lin-29 transcripts. The lin-29 cDNAs detected two poly(A+) transcripts of 2.4 and 1.8 kb in RNA blot experiments (lin-29A and lin-29B, respectively; Fig. 3A). Additional blots hybridized with radiolabeled strand-specific probes indicate these two lin-29 transcripts are ...
Document
... 4. The fatty acids esterifies to the glycerol alcohol groups can vary widely, contributing to the heterogeneity of this group of compounds. 5. Phospholipids are مهمهsynthesized in the Smooth ER-- then transported to Golgi apparatus and then membranes organelles or plasma membrane, or are secrete ...
... 4. The fatty acids esterifies to the glycerol alcohol groups can vary widely, contributing to the heterogeneity of this group of compounds. 5. Phospholipids are مهمهsynthesized in the Smooth ER-- then transported to Golgi apparatus and then membranes organelles or plasma membrane, or are secrete ...
Evolution of the eukaryotic membrane
... (vesicular, tubular or otherwise) that export material from a particular organelle for delivery to another compartment in a highly specific manner (McMahon and Mills, 2004; Robinson, 2004). Protein factors including SNAREs, tethering complexes, syntaxin-binding proteins [also known as Sec1/Munc18 (S ...
... (vesicular, tubular or otherwise) that export material from a particular organelle for delivery to another compartment in a highly specific manner (McMahon and Mills, 2004; Robinson, 2004). Protein factors including SNAREs, tethering complexes, syntaxin-binding proteins [also known as Sec1/Munc18 (S ...
Biology 13100 (by Ken Robinson, revised 2009 by NPelaez) The
... uniform in regard to the distribution of plasma membrane Ca2+ channels or other properties, so a signal may not produce uniform influx of Ca2+. Because the cytoplasm has so many components that bind Ca2+, the diffusion of Ca2+ in the cytosol is slow and Ca2+ can be elevated in one region but not ano ...
... uniform in regard to the distribution of plasma membrane Ca2+ channels or other properties, so a signal may not produce uniform influx of Ca2+. Because the cytoplasm has so many components that bind Ca2+, the diffusion of Ca2+ in the cytosol is slow and Ca2+ can be elevated in one region but not ano ...
Intercellular adhesion, signalling and the cytoskeleton
... Cdc42 mutant blocks filopodial extension and epithelial adhesion in Drosophila dorsal closure32. Although evidence is lacking for a direct interaction between E-cadherin and Cdc42, the activation of Cdc42 by E-cadherin is particularly noteworthy, because it suggests a possible molecular explanation ...
... Cdc42 mutant blocks filopodial extension and epithelial adhesion in Drosophila dorsal closure32. Although evidence is lacking for a direct interaction between E-cadherin and Cdc42, the activation of Cdc42 by E-cadherin is particularly noteworthy, because it suggests a possible molecular explanation ...
Antigen recognition by T Lymphocytes
... then transport to ER • MHC Class II: extracellular antigens, e.g. pathogen engulfed by phagocytes; degradation in phagosome and lysosome ...
... then transport to ER • MHC Class II: extracellular antigens, e.g. pathogen engulfed by phagocytes; degradation in phagosome and lysosome ...
Topic 6.5 Neuron and Synapses
... • Stage 4: neurotransmitters diffuse across the gap (synaptic cleft) and bind to receptors of the post-synaptic neuron • Stage 5: binding of neurotransmitters on receptors cause sodium ion channels to open triggers an action potential • Stage 6: neurotransmitters are either broken down or taken back ...
... • Stage 4: neurotransmitters diffuse across the gap (synaptic cleft) and bind to receptors of the post-synaptic neuron • Stage 5: binding of neurotransmitters on receptors cause sodium ion channels to open triggers an action potential • Stage 6: neurotransmitters are either broken down or taken back ...
Organelle Review
... If you wanted to scale by 100,000, what would you multiply the measurement by? A. 10-3 B. 105 C. 106 D. 107 E. 10-9 ...
... If you wanted to scale by 100,000, what would you multiply the measurement by? A. 10-3 B. 105 C. 106 D. 107 E. 10-9 ...
Document
... nuclear pores. When all the components are present, they assemble into 40S and 60S ribosomal subunits. Following assembly, the ribosomal subunits exit the nucleus through the nuclear pores and enter the cytosol. S4. Throughout chapter 13, we have seen that the general mechanism for bacterial and euk ...
... nuclear pores. When all the components are present, they assemble into 40S and 60S ribosomal subunits. Following assembly, the ribosomal subunits exit the nucleus through the nuclear pores and enter the cytosol. S4. Throughout chapter 13, we have seen that the general mechanism for bacterial and euk ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.