Therapeutic effect of MG132 on diabetic cardiomyopathy is
... inhibition of NF-κB is cardioprotective (25). Since NF-κB usually is inhibited by IκB via forming a ...
... inhibition of NF-κB is cardioprotective (25). Since NF-κB usually is inhibited by IκB via forming a ...
Pattern of mortality in sudden death: an autopsy study
... hypertension and hyperlipidaemia is very high with sudden cardiac deaths, 58%, 65% and 42% respectively and 73% of cases had history of smoking. Majority of cases are in the middle age group (Table 3,4,5,6). A smoking habit provided a significantly high correlation for sudden death of all causes and ...
... hypertension and hyperlipidaemia is very high with sudden cardiac deaths, 58%, 65% and 42% respectively and 73% of cases had history of smoking. Majority of cases are in the middle age group (Table 3,4,5,6). A smoking habit provided a significantly high correlation for sudden death of all causes and ...
Curriculum Vitae - Amazon Web Services
... I have written expert witness reports for clinical negligence pertaining to many different aspects of cardiac electrophysiology and devices over the past 5 years. I attended and then taught at the ‘Keeping Clinicians out of Court’ medico-legal course at Northwick Park Hospital for several years. Cli ...
... I have written expert witness reports for clinical negligence pertaining to many different aspects of cardiac electrophysiology and devices over the past 5 years. I attended and then taught at the ‘Keeping Clinicians out of Court’ medico-legal course at Northwick Park Hospital for several years. Cli ...
The use of reinforcement learning algorithms to meet the challenges
... techniques [21], which both take another 3–12 min [18]. Next, the digital filtering of the glucose measurement can take another 1–2 min, and is required to compensate for background noise. At this point, the algorithm will take some time to calculate the correct dose, but it is expected to be compar ...
... techniques [21], which both take another 3–12 min [18]. Next, the digital filtering of the glucose measurement can take another 1–2 min, and is required to compensate for background noise. At this point, the algorithm will take some time to calculate the correct dose, but it is expected to be compar ...
Vitamin D, Parathyroid Hormone, and Sudden
... Abstract—Recent studies have demonstrated greater risks of cardiovascular events and mortality among persons who have lower 25-hydroxyvitamin D (25-OHD) and higher parathyroid hormone (PTH) levels. We sought to evaluate the association between markers of mineral metabolism and sudden cardiac death ( ...
... Abstract—Recent studies have demonstrated greater risks of cardiovascular events and mortality among persons who have lower 25-hydroxyvitamin D (25-OHD) and higher parathyroid hormone (PTH) levels. We sought to evaluate the association between markers of mineral metabolism and sudden cardiac death ( ...
roles of oxidative stress and the mineralocorticoid receptor in
... MetS.10) The effects of aldosterone are mediated by the mineralocorticoid receptor (MR), which belongs to the nuclear receptor superfamily. Aldosterone and MR are thought to contribute both to the development of MetS and to the progression of target organ damage associated with this condition. Renal ...
... MetS.10) The effects of aldosterone are mediated by the mineralocorticoid receptor (MR), which belongs to the nuclear receptor superfamily. Aldosterone and MR are thought to contribute both to the development of MetS and to the progression of target organ damage associated with this condition. Renal ...
The Many Benefits of Apple Cider Vinegar
... 2. Apple cider vinegar reduces insulin resistance and lowers blood sugar, which can be helpful for diabetics, especially Type 2 diabetics or pre-diabetics. One study published in Diabetes Care, the journal of the American Diabetes Association, found people with Type 2 Diabetes who took two tablespoo ...
... 2. Apple cider vinegar reduces insulin resistance and lowers blood sugar, which can be helpful for diabetics, especially Type 2 diabetics or pre-diabetics. One study published in Diabetes Care, the journal of the American Diabetes Association, found people with Type 2 Diabetes who took two tablespoo ...
Book manuscript
... dosage and frequency. Lindsey had become interested in the drug in high school when her mother had been diagnosed with idiopathic cardiomyopathy—heart failure of unknown origin— at the age of forty-three. Cardiomyopathies are a strange and almost-universally-fatal type of heart failure. Thought to ...
... dosage and frequency. Lindsey had become interested in the drug in high school when her mother had been diagnosed with idiopathic cardiomyopathy—heart failure of unknown origin— at the age of forty-three. Cardiomyopathies are a strange and almost-universally-fatal type of heart failure. Thought to ...
Oxidative Stress and Salvia miltiorrhiza in Aging
... include abdominal aortic aneurysm, peripheral artery disease, unheralded coronary death, and subarachnoid hemorrhage [71]. SalA attenuates the formation of aortic aneurysms in apolipoprotein E-deficient mice by selectively inhibiting matrix metalloproteinase-9 (MMP-9) to maintain the integrity of bl ...
... include abdominal aortic aneurysm, peripheral artery disease, unheralded coronary death, and subarachnoid hemorrhage [71]. SalA attenuates the formation of aortic aneurysms in apolipoprotein E-deficient mice by selectively inhibiting matrix metalloproteinase-9 (MMP-9) to maintain the integrity of bl ...
Lower might be better – It matters how you get there, and in whom
... demonstrated that high intensity statins reduced cardiovascular events more than moderate intensity statins, some guidelines recommended a ≥50% LDL-C reduction as an alternative treatment objective for high risk patients, reflecting the average reduction in LDL-C expected from high intensity statins ...
... demonstrated that high intensity statins reduced cardiovascular events more than moderate intensity statins, some guidelines recommended a ≥50% LDL-C reduction as an alternative treatment objective for high risk patients, reflecting the average reduction in LDL-C expected from high intensity statins ...
From Incidental, Mechanically-Induced Arrhythmias to Reflex
... This concept defines different levels of autonomic components - reflexes with different length of their limbs participating in healthy and diseased cardiac/cardiovascular regulation. According to the reflex arc’s span the limbs may be categorized as ultra-short, medium and long. Thus, the first leve ...
... This concept defines different levels of autonomic components - reflexes with different length of their limbs participating in healthy and diseased cardiac/cardiovascular regulation. According to the reflex arc’s span the limbs may be categorized as ultra-short, medium and long. Thus, the first leve ...
Squatting test a dynamic postural manoeuvre OCR
... BP [7], compared to the reference tilt test, especially in diabetic patients with autonomic neuropathy. Over the first 30 s of a head-up tilt test, there is a steady parallel decline of thoracic blood volume and stroke volume; there is also an initial surge of CO followed by a steady decrease [22]. ...
... BP [7], compared to the reference tilt test, especially in diabetic patients with autonomic neuropathy. Over the first 30 s of a head-up tilt test, there is a steady parallel decline of thoracic blood volume and stroke volume; there is also an initial surge of CO followed by a steady decrease [22]. ...
Squatting test: a dynamic postural manoeuvre to study
... BP [7], compared to the reference tilt test, especially in diabetic patients with autonomic neuropathy. Over the first 30 s of a head-up tilt test, there is a steady parallel decline of thoracic blood volume and stroke volume; there is also an initial surge of CO followed by a steady decrease [22]. ...
... BP [7], compared to the reference tilt test, especially in diabetic patients with autonomic neuropathy. Over the first 30 s of a head-up tilt test, there is a steady parallel decline of thoracic blood volume and stroke volume; there is also an initial surge of CO followed by a steady decrease [22]. ...
Renal Resistive Index and Cardiovascular and
... from among those attending the outpatient clinic. In our laboratory (the National Cerebral and Cardiovascular Center), all of the hypertensive patients attended the renal sonographic laboratory, and renal sonographic data were routinely collected. Exclusion criteria included ischemic heart disease, ...
... from among those attending the outpatient clinic. In our laboratory (the National Cerebral and Cardiovascular Center), all of the hypertensive patients attended the renal sonographic laboratory, and renal sonographic data were routinely collected. Exclusion criteria included ischemic heart disease, ...
A Review on Electrophysiology Based Detection of Diabetic
... Abstract Complications of diabetes will result in Diabetic Retinopathy. The patient will not be aware of the symptoms unless it’s too late to carryout treatment. Thus early detection of diabetic retinopathy is very essential to prevent vision loss. Fundus examination is the major method of diagnosis ...
... Abstract Complications of diabetes will result in Diabetic Retinopathy. The patient will not be aware of the symptoms unless it’s too late to carryout treatment. Thus early detection of diabetic retinopathy is very essential to prevent vision loss. Fundus examination is the major method of diagnosis ...
Central Pressure More Strongly Relates to Vascular Disease and
... Heart Study. Central pressures were calculated using radial applanation tonometry. Among 3520 participants, central and brachial pulse pressures were more strongly related to vascular hypertrophy and extent of atherosclerosis than were systolic pressures. Central pulse pressure was more strongly rel ...
... Heart Study. Central pressures were calculated using radial applanation tonometry. Among 3520 participants, central and brachial pulse pressures were more strongly related to vascular hypertrophy and extent of atherosclerosis than were systolic pressures. Central pulse pressure was more strongly rel ...
Full version (PDF file)
... Fax +420 241 062 164, e-mail: [email protected], www.biomed.cas.cz/physiolres ...
... Fax +420 241 062 164, e-mail: [email protected], www.biomed.cas.cz/physiolres ...
Cardio-Oncology and stem cell transplant
... review existing evidence in oncology and non-oncology populations supporting the potential role of AT as a viable therapeutic modality to abate/attenuate HCT-associated CVD. 2. Accelerated CVD following HCT: current evidence For a comprehensive overview of CVD risk factors and CVD in HCT patients, t ...
... review existing evidence in oncology and non-oncology populations supporting the potential role of AT as a viable therapeutic modality to abate/attenuate HCT-associated CVD. 2. Accelerated CVD following HCT: current evidence For a comprehensive overview of CVD risk factors and CVD in HCT patients, t ...
Cardiovascular Systems
... 414.2x Chronic total occlusion of coronary artery, when coronary artery is 100 percent occluded for several months. 440.4 Chronic total occlusion of artery of the extremities, when there has been total artery occlusion of the arm or leg. 411.81 Acute coronary occlusion without myocardial infarction. ...
... 414.2x Chronic total occlusion of coronary artery, when coronary artery is 100 percent occluded for several months. 440.4 Chronic total occlusion of artery of the extremities, when there has been total artery occlusion of the arm or leg. 411.81 Acute coronary occlusion without myocardial infarction. ...
Annual Conference and Exhibition Programme
... Welcome to Manchester and the BCS Annual Conference 2011. You will notice major changes to the structure of the programme this year with more clearly defined “tracks” including an Innovations track which includes clinical/translational science and is supported by the British Heart Foundation, Imagin ...
... Welcome to Manchester and the BCS Annual Conference 2011. You will notice major changes to the structure of the programme this year with more clearly defined “tracks” including an Innovations track which includes clinical/translational science and is supported by the British Heart Foundation, Imagin ...
Clinical UM Guideline
... echocardiography will impact clinical decision making. 4. Kawasaki disease • initial evaluation, suspected disease; or • evaluation of an individual with established Kawasaki disease at 6-8 weeks after diagnosis to assess for coronary artery involvement; or • re-evaluation of an individual with smal ...
... echocardiography will impact clinical decision making. 4. Kawasaki disease • initial evaluation, suspected disease; or • evaluation of an individual with established Kawasaki disease at 6-8 weeks after diagnosis to assess for coronary artery involvement; or • re-evaluation of an individual with smal ...
Inhaled human insulin: a clinical perspective
... The Diabetes Control and Complications trial and the UK Prospective Diabetes Study have firmly established the importance of tight glycemic control in the prevention of long-term complications [4,5]. There is also strong evidence to suggest that early insulin initiation improves glycemic control in ...
... The Diabetes Control and Complications trial and the UK Prospective Diabetes Study have firmly established the importance of tight glycemic control in the prevention of long-term complications [4,5]. There is also strong evidence to suggest that early insulin initiation improves glycemic control in ...
The Treatment of Cardiovascular Disease with
... can be used to screen diseases, such as cardiovascular disease (Donald, & Clayton eds. 2001). The heart-health biomarkers commonly viewed in assessing the health of the heart are: blood pressure (BP), heart rate, cholesterol levels (the high-density and the low-density lipids [HDL/LDL]), C- reactive ...
... can be used to screen diseases, such as cardiovascular disease (Donald, & Clayton eds. 2001). The heart-health biomarkers commonly viewed in assessing the health of the heart are: blood pressure (BP), heart rate, cholesterol levels (the high-density and the low-density lipids [HDL/LDL]), C- reactive ...
Congestive heart failure: the case for decreased variability as a
... meals. They may also be non-routine stressors such as infection, surgery, trauma, or major blood loss. High intrinsic variability and its associated high flexibility-adaptability are characteristic of good cardiovascular health. In the syndrome of congestive heart failure, this intrinsic variability ...
... meals. They may also be non-routine stressors such as infection, surgery, trauma, or major blood loss. High intrinsic variability and its associated high flexibility-adaptability are characteristic of good cardiovascular health. In the syndrome of congestive heart failure, this intrinsic variability ...
HEART FAILURE
... 3. Volume of blood that is ejected • Increase in after load – decreases cardiac output, it will increase end diastolic volume and causes dilatation of ventricle ...
... 3. Volume of blood that is ejected • Increase in after load – decreases cardiac output, it will increase end diastolic volume and causes dilatation of ventricle ...