Mechanism of Transient Outward K Channel Block by Disopyramide
... (Fig. 5A). The use-dependent block induced by 100 mM disopyramide was accentuated at more negative HPs. For example, the steady-state level of block was 7% at 240 mV and 47% at 290 mV. In Fig. 5B, the recovery from block in the presence of disopyramide 100 mM is shown at an HP of 250 and 290 mV. The ...
... (Fig. 5A). The use-dependent block induced by 100 mM disopyramide was accentuated at more negative HPs. For example, the steady-state level of block was 7% at 240 mV and 47% at 290 mV. In Fig. 5B, the recovery from block in the presence of disopyramide 100 mM is shown at an HP of 250 and 290 mV. The ...
Atrial Fibrillation in the Wolff-Parkinson-White Syndrome
... recurrences, although he had multiple PVCs recorded in a 24 Hs Holter monitoring. 15 It may be argued that atrial vulnerability could be a predisposing factor in this kind of patients with a previous myocardial infarction. The impairment of the diastolic left ventricular function could modify the el ...
... recurrences, although he had multiple PVCs recorded in a 24 Hs Holter monitoring. 15 It may be argued that atrial vulnerability could be a predisposing factor in this kind of patients with a previous myocardial infarction. The impairment of the diastolic left ventricular function could modify the el ...
Libby: Braunwald`s Heart Disease
... stroke (0.07 to 0.14 percent), and local vascular complications (0.24 to 0.1 percent). [6] The incidence of death during coronary arteriography is higher in the presence of left main coronary artery (LMCA) disease (0.55 percent), with LVEF less than 30 percent (0.30 percent), and with New York Heart ...
... stroke (0.07 to 0.14 percent), and local vascular complications (0.24 to 0.1 percent). [6] The incidence of death during coronary arteriography is higher in the presence of left main coronary artery (LMCA) disease (0.55 percent), with LVEF less than 30 percent (0.30 percent), and with New York Heart ...
a biphasic role for the voltage
... To those who came before me, on whose shoulders I stand, and Amanda, on whose shoulders I lean. ...
... To those who came before me, on whose shoulders I stand, and Amanda, on whose shoulders I lean. ...
Electrophysiological Characteristics and
... were determined by pacing from distal pole of duodecapolar catheter and proximal pole of CS catheter respectively. It was done before and after radiofrequency ablation. AFL induction was performed by incremental and decremental pacing from lateral wall and/or CS.5 Incremental pacing was performed by ...
... were determined by pacing from distal pole of duodecapolar catheter and proximal pole of CS catheter respectively. It was done before and after radiofrequency ablation. AFL induction was performed by incremental and decremental pacing from lateral wall and/or CS.5 Incremental pacing was performed by ...
The role of altered fatty acid metabolism in cardiomyopathy and
... The heart in diabetes and obesity differs from the healthy heart. The diabetic heart has an increased and almost exclusive (90-100%) dependence on FAO to provide energy for its function (23). Furthermore, the diabetic heart is also thought to be metabolically inflexible to switch from FA to glucose ...
... The heart in diabetes and obesity differs from the healthy heart. The diabetic heart has an increased and almost exclusive (90-100%) dependence on FAO to provide energy for its function (23). Furthermore, the diabetic heart is also thought to be metabolically inflexible to switch from FA to glucose ...
Junctional tachycardias
... In atrioventricular nodal re-entrant tachycardia there are two functionally and anatomically different distinct pathways in the atrioventricular node, with different conduction velocities and different refractory periods. They share a final common pathway through the lower part of the atrioventricul ...
... In atrioventricular nodal re-entrant tachycardia there are two functionally and anatomically different distinct pathways in the atrioventricular node, with different conduction velocities and different refractory periods. They share a final common pathway through the lower part of the atrioventricul ...
ACLS PRE-TEST June, 2011
... Question 42: A patient in the emergency department develops recurrent chest discomfort (8/10) suspicious for ischemia. His monitored rhythm becomes irregular as seen above. Oxygen is being administered by nasal cannula at 4 L/min, and an IV line is in place. Blood pressure is 160/96 mm Hg. There are ...
... Question 42: A patient in the emergency department develops recurrent chest discomfort (8/10) suspicious for ischemia. His monitored rhythm becomes irregular as seen above. Oxygen is being administered by nasal cannula at 4 L/min, and an IV line is in place. Blood pressure is 160/96 mm Hg. There are ...
ECG Screening in Athletes: How does the Seattle Criteria Help?
... accurate prevalence, potential for falsenegatives, low false-positive rate may not be reproducible with less experienced interpretation. • Conclusions: feasible, low false-positive with new criteria, superior accuracy compared to H&P alone. • Greater physician infrastructure needed to apply accura ...
... accurate prevalence, potential for falsenegatives, low false-positive rate may not be reproducible with less experienced interpretation. • Conclusions: feasible, low false-positive with new criteria, superior accuracy compared to H&P alone. • Greater physician infrastructure needed to apply accura ...
Module I E.C.G. RHYTHM INTERPRETATION
... Section 2.0 – ECG Monitoring Equipment ECG Paper ECG monitors provide both dynamic and static monitoring capabilities. ECG paper has been standardized throughout the industry to maintain a running speed of 25 mm/second. It is the basis of this standard running speed that creates the large boxes wit ...
... Section 2.0 – ECG Monitoring Equipment ECG Paper ECG monitors provide both dynamic and static monitoring capabilities. ECG paper has been standardized throughout the industry to maintain a running speed of 25 mm/second. It is the basis of this standard running speed that creates the large boxes wit ...
Conus arteriosus: an anatomic and terminologic evaluation
... textbooks of cardiac surgery and cardiology, this structure should be considered in three dimensions. Therefore this structure is not only a convex area on the exterior surface of the right ventricle close to the pulmonary trunk but also outflow part of the right ventricle related with interior of t ...
... textbooks of cardiac surgery and cardiology, this structure should be considered in three dimensions. Therefore this structure is not only a convex area on the exterior surface of the right ventricle close to the pulmonary trunk but also outflow part of the right ventricle related with interior of t ...
Factors affecting tolerance to digitalis
... digitalis. Both catecholamines and excessive doses of digitalis increase the temporal dispersion of excitability recovery and, thus, facilitate ventricular fibrillation. However, there is no convincing evidence that sympathetic stimulation induces ventricular tachycardia or fibrillation in patients ...
... digitalis. Both catecholamines and excessive doses of digitalis increase the temporal dispersion of excitability recovery and, thus, facilitate ventricular fibrillation. However, there is no convincing evidence that sympathetic stimulation induces ventricular tachycardia or fibrillation in patients ...
Comprehensive characterisation of hypertensive heart disease left
... cell volume (eccentric LVH: 78±19 mL/m2 vs concentric LVH: 73±15 mL/m2 vs concentric remodelling: 55±9 mL/m2, p<0.05, respectively) and interstitial fibrosis (eccentric LVH: 33±10 mL/m2 vs concentric LVH: 30±10 mL/m2 vs concentricremodelling: 19±2 mL/m2, p<0.05, respectively). LVH had worst circumfer ...
... cell volume (eccentric LVH: 78±19 mL/m2 vs concentric LVH: 73±15 mL/m2 vs concentric remodelling: 55±9 mL/m2, p<0.05, respectively) and interstitial fibrosis (eccentric LVH: 33±10 mL/m2 vs concentric LVH: 30±10 mL/m2 vs concentricremodelling: 19±2 mL/m2, p<0.05, respectively). LVH had worst circumfer ...
Bacterial infections of the myocardium and pericardium.
... Treating early manifestation can prevent development of late complications Acutely, temporary transvenous pacing may be required for a week Routine use of intravenous antibiotics is suggested ...
... Treating early manifestation can prevent development of late complications Acutely, temporary transvenous pacing may be required for a week Routine use of intravenous antibiotics is suggested ...
Molecular distinction between physiological and pathological
... coronary artery disease, or abnormalities/conditions that lead to cardiomyopathy (e.g. inherited genetic mutations, diabetes) (Fig. 2). Both physiological and pathological heart growth are associated with an increase in heart size, however pathological hypertrophy is also typically associated with l ...
... coronary artery disease, or abnormalities/conditions that lead to cardiomyopathy (e.g. inherited genetic mutations, diabetes) (Fig. 2). Both physiological and pathological heart growth are associated with an increase in heart size, however pathological hypertrophy is also typically associated with l ...
The Cardiac Conduction System
... superior part of the sinoatrial node, runs posterior to the superior vena cava, then descends within the atrial septum and may join the anterior bundle as it enters the atrioventricular node. The third pathway is the posterior (Thorel) pathway, which generally is considered to extend from the inferi ...
... superior part of the sinoatrial node, runs posterior to the superior vena cava, then descends within the atrial septum and may join the anterior bundle as it enters the atrioventricular node. The third pathway is the posterior (Thorel) pathway, which generally is considered to extend from the inferi ...
The right ventricle, outflow tract, and ventricular
... dent lacZ reporter mice (Soriano, 1999), we show that the outflow tract, right ventricle, and the ventricular septum are marked by the activity of the mef2c-AHF-Cre transgene. In addition, the studies presented here demonstrate that cells marked by the mef2c-AHF-Cre transgene contribute to the endoc ...
... dent lacZ reporter mice (Soriano, 1999), we show that the outflow tract, right ventricle, and the ventricular septum are marked by the activity of the mef2c-AHF-Cre transgene. In addition, the studies presented here demonstrate that cells marked by the mef2c-AHF-Cre transgene contribute to the endoc ...
CPR Course
... How AED Units Work • Defibrillation works only if there is already electrical activity going on in the heart. • A defibrillator doesn't work if a person is in flat line. Since a defibrillator stops the heart, it wouldn't make sense to stop a heart that is already stopped. ...
... How AED Units Work • Defibrillation works only if there is already electrical activity going on in the heart. • A defibrillator doesn't work if a person is in flat line. Since a defibrillator stops the heart, it wouldn't make sense to stop a heart that is already stopped. ...
Demystifying the Pediatric Cardiomyopathies
... Cardiomyopathy presenting in the pre-adolescent differs significantly in possible causes, clinical expression and prognosis from that occurring in the adolescent or adult[1, 2]. Even within the pre-adolescent age group cardiomyopathy has different clinical manifestations and management concerns at d ...
... Cardiomyopathy presenting in the pre-adolescent differs significantly in possible causes, clinical expression and prognosis from that occurring in the adolescent or adult[1, 2]. Even within the pre-adolescent age group cardiomyopathy has different clinical manifestations and management concerns at d ...
13421-45587-1
... was achieved automatically, and the relapse of Tdp was recorded again after 12h (Fig. 1D). The patient was treated with magnesium and potassium and the ICD–brady ...
... was achieved automatically, and the relapse of Tdp was recorded again after 12h (Fig. 1D). The patient was treated with magnesium and potassium and the ICD–brady ...
Successful primary percutaneous coronary interventions
... rupture with subsequent thrombosis. Acute myocardial infarction is a state of increased inflammatory and hemodynamic activities which can cause further plaque destabiliza- ...
... rupture with subsequent thrombosis. Acute myocardial infarction is a state of increased inflammatory and hemodynamic activities which can cause further plaque destabiliza- ...
2001 The European Society of Cardiology
... and revise practice guidelines for important cardiovascular diseases and procedures, directs this effort. The Task Force is pleased to have this guideline cosponsored by the European Society of Cardiology (ESC). This is the first such joint effort. The Task Force wishes to acknowledge the important co ...
... and revise practice guidelines for important cardiovascular diseases and procedures, directs this effort. The Task Force is pleased to have this guideline cosponsored by the European Society of Cardiology (ESC). This is the first such joint effort. The Task Force wishes to acknowledge the important co ...
Pacing Therapies for Heart Failure (PDF Available)
... The AV node is normally the only electrical connection between the atria and the ventricles. Electrical activation proceeds from the right atrium, through the AV node to the His-Purkinje system, and then to the ventricles. The His-Purkinje system comprises myocardial cells that are specialized for r ...
... The AV node is normally the only electrical connection between the atria and the ventricles. Electrical activation proceeds from the right atrium, through the AV node to the His-Purkinje system, and then to the ventricles. The His-Purkinje system comprises myocardial cells that are specialized for r ...
Cellular hyper-excitability caused by mutations that alter the
... to that described for the cardiac sodium channel, the Nav 1.4 α-subunit is regulated by several proteins, i.e., the β1 subunit that modifies kinetics and gating (Isom, 2001). Similar to the Nav 1.5 channel, Nav 1.4 is a large protein composed of four homologous domains (I–IV), each containing six tr ...
... to that described for the cardiac sodium channel, the Nav 1.4 α-subunit is regulated by several proteins, i.e., the β1 subunit that modifies kinetics and gating (Isom, 2001). Similar to the Nav 1.5 channel, Nav 1.4 is a large protein composed of four homologous domains (I–IV), each containing six tr ...
COX-2 - HAL
... hyperthermia contributes to heat stress-induced cardioprotection in isolated rat hearts. Br J ...
... hyperthermia contributes to heat stress-induced cardioprotection in isolated rat hearts. Br J ...