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Samuel Frazer Sears Jr., Ph.D. PERSONAL INFORMATION  East Carolina University
Samuel Frazer Sears Jr., Ph.D. PERSONAL INFORMATION East Carolina University

... 10) Al-Khatib SM, Fonarow GC, Hayes DL, Curtis AB, Sears SF, Sanders GD, Hernandez AF, Mirro MJ, Thomas KL, Eapen ZJ, Russo AM, Yancy CW. Performance measures to promote quality improvement in sudden cardiac arrest prevention and treatment. Am Heart J (in press). 11) Sears, S. F., Ford, J., & Cahill ...
Today and Tomorrow
Today and Tomorrow

... Unrestricted © Siemens AG 2015 All rights reserved. Page 10 ...
Detection and management of preclinical heart failure
Detection and management of preclinical heart failure

... Juenger J et al. Health related quality of life in patients with congestive heart failure: comparison with other chronic disease and relation to functional variables. Heart 2001; 87: 235 ...
ACCF/AHA Expert Consensus Document
ACCF/AHA Expert Consensus Document

... concerning evolving areas of clinical practice and/or technologies that are widely available or new to the practice ...
Heart Lecture Test Questions – Set 2
Heart Lecture Test Questions – Set 2

... bundle branches and Purkinje fibers, the following may be stated (regarding one, or all of them): a. composed of modified cardiac muscle b. spontaneous rhythmicity and conductivity more highly developed than the rest of the heart c. initiates and transmits a depolarization wave with a rapid rate whi ...
Periodic leg movements in Cheyne–Stokes respiration CASE STUDY M. Manconi*, G. Vitale
Periodic leg movements in Cheyne–Stokes respiration CASE STUDY M. Manconi*, G. Vitale

... with sleep apnoea, the recovery of PLM by CPAP might support the hypothesis of GUGGISBERG et al. [15]. However, other studies performed in patients with RLS [11, 13, 16] or sleep apnoea [14] have reported essentially opposite findings. For these reasons, it is difficult to interpret the findings of ...
Na/K pump regulation of cardiac repolarization
Na/K pump regulation of cardiac repolarization

... Multi-scale studies of Na/K pump regulation of cardiac repolarization As mentioned earlier, the mathematical descriptions of the cardiac Na/K pump current have been integrated in a variety of models of cardiac cell electrophysiology. Computational studies using the cellular models have allowed quan ...
Rate Pressure Product as a Determinant of Physical Fitness in
Rate Pressure Product as a Determinant of Physical Fitness in

... determination of RPP is a very handy non-invasive method of knowing VO2maxand it is a simple, reliable and reproducible process serving the same purpose as that of invasive method. RPP is not only an index of O 2 consumption by the heart but also an important indicator of ventricular functional stat ...
Cecilia A. Riquelme , 528 (2011);  DOI: 10.1126/science.1210558
Cecilia A. Riquelme , 528 (2011); DOI: 10.1126/science.1210558

... function. In fact, exercise-induced physiological cardiac growth protects the heart against pathological stimuli such as pressure overload (6). The infrequently feeding Burmese python (Python molurus) has been described as a model of extreme metabolic regulation in which many organs, including the h ...
Analog Dialogue 46-11, November (2012)
Analog Dialogue 46-11, November (2012)

... All pacing leads have two electrodes, with the location of the electrodes determining the polarity of the signal. In unipolar pacing, the pacing leads consist of an electrode at the tip of a single pacing lead and the metal wall of the pacemaker housing (can) itself, so just one lead is inserted int ...
Patent ductus arteriosus - British Heart Foundation
Patent ductus arteriosus - British Heart Foundation

... are used to guide the catheter to the right position in the heart. Once the catheter is in the right position a small stainless steel coil (like the spring of pen) is threaded along the catheter and placed inside the duct to seal it closed. If the duct is large, a plug, (shaped like a tiny cork) mad ...
Palivizumab (Synagis®) Criteria for the 2015
Palivizumab (Synagis®) Criteria for the 2015

... required > 21% oxygen for at least 28 days after birth; OR  SET 2: Infant diagnosed with CLD who is 24 months of age or younger, whose second birthday is on or after November 1, 2015, infant’s second dosing season, AND the infant was born at < 32 weeks, 0 days’ gestation AND the infant required > 2 ...
CARCINOID HEART DISEASE Atrial Myxoma
CARCINOID HEART DISEASE Atrial Myxoma

... On physical examination, his heart rate was 125/min with irregular rhythm. There was grade 3 holosystolic murmur at lower left sternal border and grade II systolic ejection murmur at upper left sternal border. There was severe pitting edema in his lower legs and arms, hepatomegaly and tense Ascites ...
Assessment of Functional Capacity in Clinical and
Assessment of Functional Capacity in Clinical and

... ularly in individuals with a high aerobic capacity in whom the increase in heart rate is lower for each adjustment in work rate. Regardless of the equation used, a significant potential for error exists because of the 10- to 12-bpm SD in the estimate of maximal heart rate in normal subjects. Even gr ...
For peer review only
For peer review only

... increased blood velocity, and malfunctioning of cerebral auto-regulation6, 7. Hypotension may be an additional risk factor for stroke as a result of heart failure 8. In addition to the causal relationship, HF and ischemic stroke represent manifestations of similar underlying risk factors, such as hy ...
Effects of Moderate and Vigorous Physical Activity on Heart Rate
Effects of Moderate and Vigorous Physical Activity on Heart Rate

... The physical activity questionnaire included 20 items on the amount of time participants spent walking and cycling and involved in sports, gardening activities, housework, and house maintenance (such as home improvements) and was derived from the Minnesota leisure-time activity questionnaire (34). O ...
Coronary artery calcification score is increased in patients with
Coronary artery calcification score is increased in patients with

... visible coronary stenosis or with cardiac or extra-cardiac disease, which may potentially predispose CAE, were excluded from the study. In this way, we attempted to obtain a small but reliable study population. Although the subjects were defined as having normal coronary arteries, based on coronary ...
Untitled
Untitled

... the appropriateness of performing a procedure at the level of patient specific symptoms, medical history and test results. The aim is not to restrict the number of procedures being performed but to ensure that these are done appropriately based on current evidence. Over the last few years, there has ...
View Prescribing Information
View Prescribing Information

... Safety and effectiveness in pediatric patients have not been established. 8.5 Geriatric Use Clinical studies of ephedrine did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported clinical experience has not id ...
Distribution of normal human left ventricular myofiber stress at end
Distribution of normal human left ventricular myofiber stress at end

... www.vtk.org) to assign a local myofiber orientation to each element of the FE LV models. The material law used here has been described extensively (39, 53, 63). The key points are summarized here, and the details are given in APPENDIX A. Briefly, two different material laws were used to account for ...
CURRICULUM VITAE - McGovern Medical School
CURRICULUM VITAE - McGovern Medical School

... Molecular Genetics of Cardiomyopathies Supported by an NIH funded K08 career development grant, a major focus of my current research has been on the molecular genetics of cardiomyopathies and involved screening of a dilated cardiomyopathy patient cohort for presence of deleterious disease associated ...
The Effect of Intensified Low Density Lipoprotein Cholesterol
The Effect of Intensified Low Density Lipoprotein Cholesterol

... Figure 2. Kaplan-Meier analyses for freedom from myocardial infarction in all AMI patients. Panel A showed the patients with 3-month low density lipoprotein-cholesterol (LDL-C) decrease ‡ 40% had higher rate of freedom from myocardial infarction at 5-year follow-up than the patients with 3-month LDL ...
The Effects of Variations in Conductivity and Geometrical
The Effects of Variations in Conductivity and Geometrical

... which is abnormally posterior—explained on the basis of preferential air trapping in the anterior portion of the lungs—a phenomenon which results in lower conductivity anteriorly than posteriorly. Three possible causes for the low potentials measured in patients with obstructive lung disease are sug ...
Current and Evolving Echocardiographic Techniques for the Quantitative Evaluation
Current and Evolving Echocardiographic Techniques for the Quantitative Evaluation

... stored in a raw data format. Older imaging systems that store only color values in an image should not be used unless postprocessing is not planned. Acquisition of blood flow Doppler spectra of the inlet and outlet valves of the interrogated ventricle provides useful information for timing of openin ...
Clinical Cardiology: New Frontiers
Clinical Cardiology: New Frontiers

... failure demonstrate improved brachial artery nitric oxide– dependent, flow-mediated dilation after exercise training.42 No study has yet examined the effect of exercise training on coronary artery endothelial function in humans. Autonomic Function The balance between sympathetic and parasympathetic ...
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