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Vitamin D dosing for vitamin D deficiency?
... Where rapid correction of vitamin D deficiency is required, such as in patients with symptomatic disease or those about to start treatment with a potent antiresorptive agent (zoledronate or denosumab) the recommended treatment regimen is based on fixed loading doses followed regular maintenance ther ...
... Where rapid correction of vitamin D deficiency is required, such as in patients with symptomatic disease or those about to start treatment with a potent antiresorptive agent (zoledronate or denosumab) the recommended treatment regimen is based on fixed loading doses followed regular maintenance ther ...
Excessive daytime sleepiness in Parkinson`s disease
... 'Evidence summaries: unlicensed or off-label medicines' summarise the published evidence for selected unlicensed or off-label medicines that are considered to be of significance to the NHS, where there are no clinically appropriate licensed alternatives. The summaries provide information for clinici ...
... 'Evidence summaries: unlicensed or off-label medicines' summarise the published evidence for selected unlicensed or off-label medicines that are considered to be of significance to the NHS, where there are no clinically appropriate licensed alternatives. The summaries provide information for clinici ...
Prescribing - North Essex Partnership University NHS Foundation
... 5.8.5. If a Consultant wishes to use an unlicensed medicine not on the approved list, a nonformulary request (Form B – see below) should be submitted to the MMG. 5.8.6. As per the GMC, before prescribing an unlicensed medicine the must prescriber must: Be satisfied there is sufficient evidence or ...
... 5.8.5. If a Consultant wishes to use an unlicensed medicine not on the approved list, a nonformulary request (Form B – see below) should be submitted to the MMG. 5.8.6. As per the GMC, before prescribing an unlicensed medicine the must prescriber must: Be satisfied there is sufficient evidence or ...
Managing Systems - University of the Western Cape
... basis of need … A national committee for supplies and equipment should then combine the lists for each level of care into one list of essential medical supplies and equipment. Like the list of essential drugs, this list should be the basis for standardized procurement and distribution of supplies an ...
... basis of need … A national committee for supplies and equipment should then combine the lists for each level of care into one list of essential medical supplies and equipment. Like the list of essential drugs, this list should be the basis for standardized procurement and distribution of supplies an ...
MRCC
... The available data on quality of life from the Motzer et al trial were limited but suggested patient-reported quality of life, as assessed by the Functional Assessment of Cancer Therapy-General (FACT-G), was better with sunitinib (Sutent). Mean total FACT-G scores were higher with sunitinib (Sutent) ...
... The available data on quality of life from the Motzer et al trial were limited but suggested patient-reported quality of life, as assessed by the Functional Assessment of Cancer Therapy-General (FACT-G), was better with sunitinib (Sutent). Mean total FACT-G scores were higher with sunitinib (Sutent) ...
NOVEMBER 2016 PBAC OUTCOMES – 1ST TIME DECISIONS NOT
... there was no clinical need to list this new brand of fluticasone with salmeterol on the PBS. The sponsor is disappointed with the PBAC outcome for Airflusal® Forspiro® 500/50. We respectfully disagree with the concerns raised. From a safety and efficacy perspective, these concerns have been thorough ...
... there was no clinical need to list this new brand of fluticasone with salmeterol on the PBS. The sponsor is disappointed with the PBAC outcome for Airflusal® Forspiro® 500/50. We respectfully disagree with the concerns raised. From a safety and efficacy perspective, these concerns have been thorough ...
Protocol S1.
... drug resistance through different mechanisms (Nosten and Brasseur 2002). Artemisinin drugs in combination with a variety of partner drugs have proved highly effective in a number of field trials (International Artemisinin Study Group 2002). Although the costs for artemisinin combination therapy (ACT ...
... drug resistance through different mechanisms (Nosten and Brasseur 2002). Artemisinin drugs in combination with a variety of partner drugs have proved highly effective in a number of field trials (International Artemisinin Study Group 2002). Although the costs for artemisinin combination therapy (ACT ...
Diagnosis and medical treatment of lower urinary tract symptoms in
... simplified for use as a quick reference guide for healthcare professionals managing LUTS in adult males. ...
... simplified for use as a quick reference guide for healthcare professionals managing LUTS in adult males. ...
Economic Analysis of Panitumumab Compared With Cetuximab in
... challenges and constraints that payers face. Costminimization analysis is a method that should be used only to measure and compare the costs of different medical interventions in economic evaluations of trials demonstrating no statistically significant difference in efficacy. However, Briggs and O’Bri ...
... challenges and constraints that payers face. Costminimization analysis is a method that should be used only to measure and compare the costs of different medical interventions in economic evaluations of trials demonstrating no statistically significant difference in efficacy. However, Briggs and O’Bri ...
What CATIE Found: Results From the Schizophrenia Trial
... were excluded from being randomly assigned to perphenazine and were assigned to one of the four second-generation antipsychotics in phase 1A. Clozapine was included in phase 2 of the study. Overall, olanzapine had the longest time to discontinuation in phase 1, but it was associated with significant ...
... were excluded from being randomly assigned to perphenazine and were assigned to one of the four second-generation antipsychotics in phase 1A. Clozapine was included in phase 2 of the study. Overall, olanzapine had the longest time to discontinuation in phase 1, but it was associated with significant ...
(PSD) March 2015 PBAC meeting
... Vedolizumab March 2014 submission PBAC Comment: ‘…PBAC observed that both vedolizumab and infliximab showed statistically significant better response rates and remission rates at week 6-8 and 52 compared to placebo. The indirect comparison of infliximab and vedolizumab demonstrated a similar respons ...
... Vedolizumab March 2014 submission PBAC Comment: ‘…PBAC observed that both vedolizumab and infliximab showed statistically significant better response rates and remission rates at week 6-8 and 52 compared to placebo. The indirect comparison of infliximab and vedolizumab demonstrated a similar respons ...
EA_QA47.7Methylphenidateinadults
... use of methylphenidate and sudden death, however, given the lack of background rates the evidence is inconclusive. The GDG concluded that methylphenidate is effective in reducing ADHD core symptoms and in producing clinical improvement as rated by investigators in adults with ADHD and high dose meth ...
... use of methylphenidate and sudden death, however, given the lack of background rates the evidence is inconclusive. The GDG concluded that methylphenidate is effective in reducing ADHD core symptoms and in producing clinical improvement as rated by investigators in adults with ADHD and high dose meth ...
Augmentation Clinical Presentation Biological Basis
... Or two of the following 1. Intensity increase with increasing dose 2. Decreased intensity with decreasing dose 3. Shorter rest time to provoke symptoms than before Rx 4. RLS Sx occur in previously unaffected limbs or body parts 5. Shorter duration of Rx benefit than with initial treatment 6. PLMS or ...
... Or two of the following 1. Intensity increase with increasing dose 2. Decreased intensity with decreasing dose 3. Shorter rest time to provoke symptoms than before Rx 4. RLS Sx occur in previously unaffected limbs or body parts 5. Shorter duration of Rx benefit than with initial treatment 6. PLMS or ...
Common errors in multidrug-resistant tuberculosis management
... of other treatments. Nevertheless, rifampicin and isoniazid resistance confirmation and species differentiation is always advisable [7,19,20]. In any case, the use of second-line drugs to treat susceptible TB is still a life-saving measure but implies consuming precious resources. Accelerating the c ...
... of other treatments. Nevertheless, rifampicin and isoniazid resistance confirmation and species differentiation is always advisable [7,19,20]. In any case, the use of second-line drugs to treat susceptible TB is still a life-saving measure but implies consuming precious resources. Accelerating the c ...
Herbal Treatments Chapter 4
... currently being used to treat cancer in a way that is distinct both from the context of traditional herbal practices and from conventional drug development. Some of them may have had roots in traditional practices, but have since been removed from that context and offered independently or in conjunc ...
... currently being used to treat cancer in a way that is distinct both from the context of traditional herbal practices and from conventional drug development. Some of them may have had roots in traditional practices, but have since been removed from that context and offered independently or in conjunc ...
safety reporting requirements for clinical drug trials
... other appropriate people aware of new, important information on serious reactions. Therefore, such reporting will generally involve events previously unobserved or undocumented, and a guideline is needed on how to define an event as “unexpected” or “expected” (expected/unexpected from the perspectiv ...
... other appropriate people aware of new, important information on serious reactions. Therefore, such reporting will generally involve events previously unobserved or undocumented, and a guideline is needed on how to define an event as “unexpected” or “expected” (expected/unexpected from the perspectiv ...
The Way Forward: Stewardship for Prescription Narcotics in Ontario
... 4. Preparing for change: Strategic directions.................................................................................................................17 A focus on harm reduction ................................................................................................................. ...
... 4. Preparing for change: Strategic directions.................................................................................................................17 A focus on harm reduction ................................................................................................................. ...
treatmentexperienced.. - University of Washington
... time of virologic failure • Adjusted mortality was higher for individuals who remained on first-line therapy than for those who had switched (OR 2.1, 95% CI 1.1–4.2) Petersen AIDS 2014 ...
... time of virologic failure • Adjusted mortality was higher for individuals who remained on first-line therapy than for those who had switched (OR 2.1, 95% CI 1.1–4.2) Petersen AIDS 2014 ...
Shared care available
... In addition general practitioners may occasionally need to undertake blood tests, e.g. in patients taking ergot derivatives, but if so this will be recommended in writing in a letter from the clinic (see above). In all cases it is the responsibility of the prescriber to ensure that appropriate monit ...
... In addition general practitioners may occasionally need to undertake blood tests, e.g. in patients taking ergot derivatives, but if so this will be recommended in writing in a letter from the clinic (see above). In all cases it is the responsibility of the prescriber to ensure that appropriate monit ...
Health Psychology From Ideas to Efficacy
... emotion, cognition, self-regulation, decision-making, stress, and social networks are not being optimally applied to pressing behavioral health problems. Promising behavioral treatments “in the pipeline” are often abandoned, rather than refined, if they fail early tests. In some cases, treatments th ...
... emotion, cognition, self-regulation, decision-making, stress, and social networks are not being optimally applied to pressing behavioral health problems. Promising behavioral treatments “in the pipeline” are often abandoned, rather than refined, if they fail early tests. In some cases, treatments th ...
UKMi - Wolverhampton Formulary
... 8. Summary of Product Characteristics –Durogesic DTrans 12/25/50/75/100mcg/hr Transdermal Patch. Accessed online at http://www.medicines.org.uk/emc/medicine/17086/SPC/ on 12/06/12 [date of revision of the text 20th January 2012] 9. Summary of Product Characteristics – Fencino 75 micrograms/hour Tran ...
... 8. Summary of Product Characteristics –Durogesic DTrans 12/25/50/75/100mcg/hr Transdermal Patch. Accessed online at http://www.medicines.org.uk/emc/medicine/17086/SPC/ on 12/06/12 [date of revision of the text 20th January 2012] 9. Summary of Product Characteristics – Fencino 75 micrograms/hour Tran ...
QA408_3_Pregabalin_gabapentin_March2015
... to gabapentin following pregabalin treatment or vice versa. The individual SPCs suggest that both agents should be discontinued over the course of a week, although whether this is relevant for patients with neuropathic pain remains unclear. Any decisions made will need to be based on a clinical judg ...
... to gabapentin following pregabalin treatment or vice versa. The individual SPCs suggest that both agents should be discontinued over the course of a week, although whether this is relevant for patients with neuropathic pain remains unclear. Any decisions made will need to be based on a clinical judg ...
Perioperative anesthesia clinical considerations of
... nutraceutical popularity reemerged and in 1992, this increasing popularity of herbal products led to the establishment of the Office of Alternative Medicines by the National Institutes of Health in Bethesda, Maryland. The contribution of botanicals cannot be overlooked because 30% of all modern conv ...
... nutraceutical popularity reemerged and in 1992, this increasing popularity of herbal products led to the establishment of the Office of Alternative Medicines by the National Institutes of Health in Bethesda, Maryland. The contribution of botanicals cannot be overlooked because 30% of all modern conv ...
clinical trials patient-assisted research studies What you need to know about...
... options. Whether you or someone you care about has been diagnosed with lung cancer, or you are concerned about your lung cancer risk, we have resources to help you. The medical experts and lung cancer survivors who provided their valuable expertise and experience in developing these materials all sh ...
... options. Whether you or someone you care about has been diagnosed with lung cancer, or you are concerned about your lung cancer risk, we have resources to help you. The medical experts and lung cancer survivors who provided their valuable expertise and experience in developing these materials all sh ...
Article - The Probation Service
... and improvement in home stability. The findings from this study showed that at the end of the first year clients treated in maintenance programmes showed reductions in the frequency of their drug use by nearly half. The proportion of clients injecting also decreased significantly, thereby also reduc ...
... and improvement in home stability. The findings from this study showed that at the end of the first year clients treated in maintenance programmes showed reductions in the frequency of their drug use by nearly half. The proportion of clients injecting also decreased significantly, thereby also reduc ...