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NEW_DRUG_APPLICATION
NEW_DRUG_APPLICATION

... 8 Regulatory status in other countries 9. Marketing information: ...
THE CROSSROADS OF PHARMACEUTICAL
THE CROSSROADS OF PHARMACEUTICAL

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Regulatory Considerations in the Post-Vioxx Era
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... The US environment for drug development and registration has evolved as a result of many significant and public events that span the course of the past century. In the early 1900s, public outcry following the exposure of deplorable conditions in meat packing plants and false claims about patented m ...
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... This is in responseto your letter of June 15,200l to the Food and Drug Administration (FDA) pursuant to 21 U.S.C. 343(r)(6) (section 403(r)(6) of the Federal Food, Drug, and Cosmetic Act (the Act)). Your submissionstatesthat Tabak’s Health Products is marketing the product CholestLo, which contains ...
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FDA Basics For Biotech Drugs, Biologics and Devices

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... study in patients with renal impairment was conducted. The study demonstrated a significant difference in PK between patients with moderate and severe renal impairment compared to those with normal renal function. Also, 52% of the dose was recovered in the dialysate following dialysis. • In Phase 2/ ...
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... Ophthalmic is developing a liposomal latanoprost for subconjunctival injection; the drug lowered mean IOP from 28 to 15 mm Hg in an open-label study of six patients.21 Allergan is evaluating an erodible, anterior chamber implant of bimatoprost (EudraCT 2011005091-42). BioLight Israeli Life Sciences ...
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... The Food and Drug Administration (FDA) is issuing a public health advisory concerning phenylpropanolamine hydrochloride. This drug is widely used as a nasal decongestant (in over-the-counter and prescription drug products) and for weight control (in over-the-counter drug products). FDA is taking ste ...
korenchuk_5
korenchuk_5

... Motivating patients to contact their physicians and engage in a dialogue about health concerns; Increasing the likelihood that patients will receive appropriate care for conditions that are frequently under-diagnosed and undertreated; and Encouraging compliance with prescription drug treatment regim ...
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The process of evaluating and regulating a new durg

... and allied products industries.1 Yet bringing a drug to market is a complex, timeconsuming, and expensive process. Billions of dollars are spent each year on the discovery and development of new drugs. It is estimated that pharmaceutical companies spend an average $125 million on the development of ...
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Anorectics on Trial: A Half Century of Federal Regulation of

... THE FIRST FDA-APPROVED OBESITY DRUGS In November 1943, Abbott Laboratories of Abbott Park, Illinois, submitted a New Drug Application (NDA) for desoxyephedrine (Desoxyn) to the FDA’s Drug Division. The company was seeking approval of their amphetamine for the treatment of narcolepsy, mild depression ...
Recent False Claims Developments
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...  Relators allege Aventis marketed a drug for numerous off-label uses  Caused medical providers to submit fraudulent Medicare claims  Court dismissed federal and “parallel” Illinois FCA claims ...
< 1 ... 11 12 13 14 15 16 17 18 19 ... 31 >

List of off-label promotion pharmaceutical settlements

The following are settlements reached against pharmaceutical companies to resolve allegations of off-label promotion of drugs. Under the Federal Food, Drug, and Cosmetic Act, it is illegal for pharmaceutical companies to promote their products for uses not approved by the Food and Drug Administration (FDA), and corporations that market drugs for off-label indications may be subject to civil liability under the False Claims Act as well as criminal penalties.
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