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Biotechnology and its applications - MrsGorukhomework
Biotechnology and its applications - MrsGorukhomework

... Biotechnology and its applications p. 158 Human Genome Project – The identification of the human genome, that is, finding out all the base sequences. Mapping of genes – what the sequence codes for. (did mapping of genome of yeast in 1992 just for chromosome 3 which consisted of 315 357 nucleotides, ...
Clustering for Accuracy, Performance, and Alternative
Clustering for Accuracy, Performance, and Alternative

... regions more often than expected by chance ...
Ch. 10.4: Meiosis & Mendel`s Principles
Ch. 10.4: Meiosis & Mendel`s Principles

... present in gamete is random … depends on how chromosomes line up during metaphase. ...
Research News
Research News

... It is now the normal practice in preparing phylogenetic trees of fungal lineages to use sequences of several different genes, but testing whether the selected genes are the most appropriate is necessarily somewhat subjective. This is especially so as incongruent trees can be produced. As more comple ...
BIOL 2416 Genetics
BIOL 2416 Genetics

... • Seeks to compare all or part of the genomes of two or more strains or species • Allows researchers to hone in on crucial genetic differences between strains/species/cell types. For example: – Using computer analysis: • May discover which gene(s) cause one virus to be more virulent than another • C ...
Introduction to Genetics
Introduction to Genetics

... The term genotype the genes present in the DNA of an organism. We will use a pair of letters (ex: Tt or YY or ss, etc.) to represent genotypes for one particular trait. There are always two letters in the genotype because (as a result of sexual reproduction) one code for the trait comes from mama or ...
Genetic Controls in Eukaryotes
Genetic Controls in Eukaryotes

...  Regulation at post-transcriptional level - RNA processing o Alternative RNA splicing = different segments of RNA are treated as exons and introns = different mRNA o Controlled by regulatory proteins specific to each cell type o Consequence = a single gene can code for more than one polypeptide = ...
Gene Section AF9 (ALL1 fused gene from chromosome 9)
Gene Section AF9 (ALL1 fused gene from chromosome 9)

... Hybrid/Mutated Gene Variable breakpoints on both genes. Abnormal Protein N-term -- AT hook and DNA methyltransferase from MLL fused to the 192 C-term amino acids from AF9 (as breakpoints are variable, this is only an exemple). ...
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... PACdb is a Pharmacogenetics and Cell line database for use as a central repository of pharmacology-related phenotypes that integrates genotypic, gene expression, and pharmacological data obtained via lymphoblastoid cell lines (LCLs), particularly the HapMap CEU (Caucasians from Utah, USA) and YRI (Y ...
Morgan and Sex Linkage / Mutations
Morgan and Sex Linkage / Mutations

... 1 nucleotide is replaced by a different nucleotide, results in a new codon. It COULD affect one amino acid. - If substituted nucleotide does not change AA, no affect on organism - If substituted nucleotide does change AA, resulting protein will be altered, affecting the organism. ...
Differential Gene Expression
Differential Gene Expression

... Arabidopsis: member of mustard family just like the Brassica rapa; can be grown in culture (in test tubes); has a small genome; each flower has egg and sperm; cells take up foreign DNA quickly. ...
here
here

Introduction to Molecular Biology and Genomics
Introduction to Molecular Biology and Genomics

... For a completely distinguishing gene where, all of its values for class P are ‘h’, and all of its values for class N are ‘l’, Lg , P  H g , N  0 and, rg , takes its maximum positive value. In this case the gene is considered to be descriptive of (associated with) class P. The gene remains complete ...
homologous pairs
homologous pairs

... 1. Matching sets of chromosomes are called ________ pairs 2. Egg and sperm combine to make a _______________ 3. Egg and sperm are both known as _______________ 4. A cell that only has half of a set of chromosomes is said to be _______________. 5. Genes are located on ___________________ ...
9.
9.

... homology and therefore have similar distributions of constrained sites. The most likely origin of structural homology between interacting proteins is duplication of the gene that encodes a homodimeric protein, followed by evolution of one copy of the gene. This process would result in homology not o ...
TAIR Gene Ontology (GO) Annotations
TAIR Gene Ontology (GO) Annotations

... The Gene Ontology is a set of controlled vocabularies used to describe three qualities of gene products: • Biological process: pathways and larger processes made up of the activities of multiple gene products. • Molecular function: molecular activities of gene products • Cellular component: where ge ...
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1 BIOL 213 Fourth Exam All atoms, chemical bonding and structures

... Transcription of eucaryotic mRNA genes Transcription of eucaryotic tRNA genes Transcription of eucaryotic rRNA genes DNA synthesis from RNA template RNA synthesis from RNA template ...
go-interpretation-analysis-2014
go-interpretation-analysis-2014

... GO has made a term enrichment tool available on the website  Beginning to use our own data in the same way our users most commonly use it  This was not a goal of the GO grant. Instead, we had proposed:  We will define test datasets that will allow software developers to benchmark their products. ...
CMO Recessive or Dominant with Incomplete Penetrance
CMO Recessive or Dominant with Incomplete Penetrance

... It turns out, if you study this, that the two modes are not that statistically different. At first glance, it looks like they differ a great deal in one practical aspect for breeders but even that is surmountable. Dr. Padgett was right for his time and the technology he had available. He was aware t ...
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... one trait with two phenotypes Punnett Square-device for predicting possible offspring of crosses between different ...
Functional genomics and gene chips
Functional genomics and gene chips

... Microarray data analysis The analysis of microarray data is complex and involves several steps. After hybridisation, microarrays are scanned and images representing the intensity of the fluorescence signal are generated. After image processing, it is necessary to normalise the fluorescence intensiti ...
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Lecture 21 Student Powerpoint

... Need to deliver nanoliter to picoliter volumes a. Too small for normal pipetting devices 3. Robot “prints,” or “spots,” DNA in specific places ...
RNA-Seq - iPlant Pods
RNA-Seq - iPlant Pods

... • Accesses XSEDE system through the iPlant Agave API • Co-localizes up to 100 GB of data in iPlant Data Store • Look for differential gene expression in different tissues, life stages, or treatment • Generate lists of expressed genes and fold-changes • Annotate sequenced genomes; add results to Red ...
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Supplementary Information (doc 46K)

... is unknown, reverse unidirectional alterations (from right to left) or bidirectional ...
IV. Genetics: The Science of Heredity A. Mendel`s Work 1. Gregor
IV. Genetics: The Science of Heredity A. Mendel`s Work 1. Gregor

... 3. Meiosis is the process by which the number of chromosomes is reduced by half to form sex cells, called sperm and egg cells. D. The DNA Connection 1. Genes (on chromosomes) tell the cell how to make proteins. 2. Making proteins is called protein synthesis. 3. RNA carries the code from the genes in ...
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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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