Slide 1
... To identify yeast gene products important for accurate chromosome transmission in mitosis. Importance: Errors during chromosome transmission in humans can lead to cell death, genetic disorders (e.g., Down Syndrome), and cancer. Experimental Strategy: Plasmids containing yeast genes that suppress ...
... To identify yeast gene products important for accurate chromosome transmission in mitosis. Importance: Errors during chromosome transmission in humans can lead to cell death, genetic disorders (e.g., Down Syndrome), and cancer. Experimental Strategy: Plasmids containing yeast genes that suppress ...
Pedigree Chart
... Late in the summer of 1818, a human sperm and egg united to form a human zygote. One of those gametes, we don't know which, was carrying a newly mutated gene. A single point mutation in a nucleotide sequence coding for a particular amino acid in a protein essential for blood clotting. The zygote bec ...
... Late in the summer of 1818, a human sperm and egg united to form a human zygote. One of those gametes, we don't know which, was carrying a newly mutated gene. A single point mutation in a nucleotide sequence coding for a particular amino acid in a protein essential for blood clotting. The zygote bec ...
Supplementary material
... ESTs for a particular clone. For clones without a cDNA sequence and thus no clear representative sequence, the highest-scoring EST match to the representative gene is chosen as the representative sequence. Close to 1,000 of the clones find multiple potential genes with our method. This often is a r ...
... ESTs for a particular clone. For clones without a cDNA sequence and thus no clear representative sequence, the highest-scoring EST match to the representative gene is chosen as the representative sequence. Close to 1,000 of the clones find multiple potential genes with our method. This often is a r ...
Low dose irradiation profoundly affects transcriptome and
... to cells [20]. The activated genes were CD247 (it plays a role in signal transduction upon antigen triggering), Icam 1 and 2 (they are ligands for leukocyte adhesion), lat (a linker for T activation), among others. The enhancement of NK cell-mediated cytotoxicity after radiation in combination with ...
... to cells [20]. The activated genes were CD247 (it plays a role in signal transduction upon antigen triggering), Icam 1 and 2 (they are ligands for leukocyte adhesion), lat (a linker for T activation), among others. The enhancement of NK cell-mediated cytotoxicity after radiation in combination with ...
wanted - Copenhagen Plant Science Centre
... DNA that does not code for proteins (non-coding DNA) makes up the vast majority of bases in many genomes yet we understand little about its role. Non-coding regions are actively transcribed by the same complex transcribing genes (RNA polymerase II, Pol II). Transcription of non-coding sequences resu ...
... DNA that does not code for proteins (non-coding DNA) makes up the vast majority of bases in many genomes yet we understand little about its role. Non-coding regions are actively transcribed by the same complex transcribing genes (RNA polymerase II, Pol II). Transcription of non-coding sequences resu ...
Text S1.
... dams and their litters were housed with food and water ad libitum and monitored in accordance with the rules of the Department of Laboratory Animal Medicine at Tufts Medical Center. The inoculum was prepared from the premixed frozen stock of 35 deletions strains diluted 1:100 and grown to mid-log. M ...
... dams and their litters were housed with food and water ad libitum and monitored in accordance with the rules of the Department of Laboratory Animal Medicine at Tufts Medical Center. The inoculum was prepared from the premixed frozen stock of 35 deletions strains diluted 1:100 and grown to mid-log. M ...
The angiotensin-converting enzyme (ACE) gene family ofAnopheles
... twenty-six exons and two promoters, and has clearly arisen by gene duplication [4]. The somatic promoter drives expression of the larger protein (exons 1–12 and exons 14–26), which consists of two very similar domains connected in tandem by a short inter-domain peptide. Each domain possesses a funct ...
... twenty-six exons and two promoters, and has clearly arisen by gene duplication [4]. The somatic promoter drives expression of the larger protein (exons 1–12 and exons 14–26), which consists of two very similar domains connected in tandem by a short inter-domain peptide. Each domain possesses a funct ...
The BCM Microarray Core Facility
... single-reads, short- and long-insert paired-end reads for whole-genome sequencing and resequencing, SNP discovery, identification of copy number variations and chromosomal rearrangements. ...
... single-reads, short- and long-insert paired-end reads for whole-genome sequencing and resequencing, SNP discovery, identification of copy number variations and chromosomal rearrangements. ...
Heredity
... Independent assortment—multiple traits, seed shape and seed color Mendel followed two traits together to see if they influenced each other. Vertically at left, the phenotypic outcomes into the F2 generation are followed for seed shape—round (dominant) and wrinkled (recessive); and seed color—yellow ...
... Independent assortment—multiple traits, seed shape and seed color Mendel followed two traits together to see if they influenced each other. Vertically at left, the phenotypic outcomes into the F2 generation are followed for seed shape—round (dominant) and wrinkled (recessive); and seed color—yellow ...
The role of dSAGA specific histone acetylation in regulation of gene
... L3 larvae and early pupa). By comparing the mRNA profiles we determined genes showing altered expression level in the absence of dADA2b. At both time points analyzed only a small subset of genes (5 %) were regulated by dSAGA complex. Despite the supposed role of histone acetylation in transcription ...
... L3 larvae and early pupa). By comparing the mRNA profiles we determined genes showing altered expression level in the absence of dADA2b. At both time points analyzed only a small subset of genes (5 %) were regulated by dSAGA complex. Despite the supposed role of histone acetylation in transcription ...
JGU_ProteinBCshort - Computational Biology and Data Mining group
... Stefan Legewie & Stephan Baumgaertner Institute of Molecular Biology, Mainz ...
... Stefan Legewie & Stephan Baumgaertner Institute of Molecular Biology, Mainz ...
Whole-genome expression analysis of snf swi mutants of
... transcriptional repression. This idea has come from a combination of gene expression studies (21–24), biochemical analysis of nucleosome remodeling by human Snf兾Swi (25) and the Snf兾 Swi-related S. cerevisiae complex, RSC (26), and from wholegenome expression studies (6). It is unclear whether Snf兾S ...
... transcriptional repression. This idea has come from a combination of gene expression studies (21–24), biochemical analysis of nucleosome remodeling by human Snf兾Swi (25) and the Snf兾 Swi-related S. cerevisiae complex, RSC (26), and from wholegenome expression studies (6). It is unclear whether Snf兾S ...
Analyze and evaluate the effects of other evolutionary
... • Natural disaster like flood, fire, or earthquake • A random change of the population (some are eliminated) • Different from natural selection b/c its by chance or randomly ...
... • Natural disaster like flood, fire, or earthquake • A random change of the population (some are eliminated) • Different from natural selection b/c its by chance or randomly ...
14.1 Formation and Early History of Earth
... The lack of divergence of the 16S rRNA gene limits its effectiveness in discriminating between bacteria at the species level, thus, a multi-gene approach can be used Multi-gene sequence analysis is similar to MLST, but uses complete sequences and comparisons are made using cladistic methods ...
... The lack of divergence of the 16S rRNA gene limits its effectiveness in discriminating between bacteria at the species level, thus, a multi-gene approach can be used Multi-gene sequence analysis is similar to MLST, but uses complete sequences and comparisons are made using cladistic methods ...
XML
... Lymphoma represents a heterogeneous group of neoplastic blood disorders involving monoclonal proliferation of malignant lymphocytes. Historically, lymphomas have been divided in two basic categories: Hodgkin lymphoma (HL) and Non-Hodgkin lymphoma (NHL) (DeVita et al., 2015). Different subtypes were ...
... Lymphoma represents a heterogeneous group of neoplastic blood disorders involving monoclonal proliferation of malignant lymphocytes. Historically, lymphomas have been divided in two basic categories: Hodgkin lymphoma (HL) and Non-Hodgkin lymphoma (NHL) (DeVita et al., 2015). Different subtypes were ...
Proximal promoter
... the distal sequence upstream of the gene that may contain additional regulatory elements, often with a weaker influence than the proximal promoter – Anything further upstream (but not an enhancer or other regulatory region whose influence is positional/orientation independent) – Specific transcripti ...
... the distal sequence upstream of the gene that may contain additional regulatory elements, often with a weaker influence than the proximal promoter – Anything further upstream (but not an enhancer or other regulatory region whose influence is positional/orientation independent) – Specific transcripti ...
Additional File 1
... generated are not by chance, their reproducibility was examined by a resampling procedure [3] Two methods to generate Z-summary scores were used. First, module statistics of the merged dataset (reference dataset) was compared to the randomly generated modules in a test dataset, which comprised 100 r ...
... generated are not by chance, their reproducibility was examined by a resampling procedure [3] Two methods to generate Z-summary scores were used. First, module statistics of the merged dataset (reference dataset) was compared to the randomly generated modules in a test dataset, which comprised 100 r ...
Biology~Chapter 12
... -each sperm has an equal chance of having an X or a Y -however- the only option for eggs is to receive an X chromosome. ...
... -each sperm has an equal chance of having an X or a Y -however- the only option for eggs is to receive an X chromosome. ...
Chromosomal Rearrangements I
... (multigenic). Deletions can arise from DNA damage (X-rays or chemical agents that break chromosomes), or from mistakes during recombination or replication. If the deleted region does not contain any genes essential for survival, an individual homozygous for a deletion (Del/Del) will live. An example ...
... (multigenic). Deletions can arise from DNA damage (X-rays or chemical agents that break chromosomes), or from mistakes during recombination or replication. If the deleted region does not contain any genes essential for survival, an individual homozygous for a deletion (Del/Del) will live. An example ...
Presentation
... – Uses reverse transcriptase and PCR – Compares gene expression between different samples ...
... – Uses reverse transcriptase and PCR – Compares gene expression between different samples ...
yanting-talk
... • The table below shows the details about the biclusters/patterns discovered using the RAP, CC and ISA algorithm by using different parameter settings. The size range and coverage numbers are computed only for the finally selected non-overlapping patterns. ...
... • The table below shows the details about the biclusters/patterns discovered using the RAP, CC and ISA algorithm by using different parameter settings. The size range and coverage numbers are computed only for the finally selected non-overlapping patterns. ...
Fulltext PDF
... Repair of DNA Damage and Maintenance of Chromosomal Integrity One of the important requirements for normal tissue function is that the integrity of DNA is maintained from one division cycle to another. If DNA is damaged due to exposure to ionizing radiation, UV or chemicals, progression in cell cycl ...
... Repair of DNA Damage and Maintenance of Chromosomal Integrity One of the important requirements for normal tissue function is that the integrity of DNA is maintained from one division cycle to another. If DNA is damaged due to exposure to ionizing radiation, UV or chemicals, progression in cell cycl ...
Differential Expression Analysis
... Example of the Problem Suppose that 1000 genes are represented on an array and we test each with a t test with a Type I error threshold of 0.05. We might expect 40 genes to be differentially expressed. Of the 960 non-differentially expressed genes we can expect 5% errors, or .05 × 960 = 48 false pos ...
... Example of the Problem Suppose that 1000 genes are represented on an array and we test each with a t test with a Type I error threshold of 0.05. We might expect 40 genes to be differentially expressed. Of the 960 non-differentially expressed genes we can expect 5% errors, or .05 × 960 = 48 false pos ...
Gene expression profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.