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Arabidopsis
Arabidopsis

... approach is superior in the resolution of segmental duplications, it would be unrealistic to propose that the sequencing community should abandon wholegenome-shotgun based approaches. These are the most efficient cost-effective means of capturing the bulk of the euchromatic sequence.” Evan E. Eichle ...
No Slide Title
No Slide Title

... • GUS and garlic transgenes only expressed in presence of inducer (ethanol) ...
Genes and Genomes
Genes and Genomes

...  DNA markers 'mark' locations where DNA sequence varies (2 or more alleles) – Such polymorphisms can vary within and among individuals (e.g. heterozygotes vs. homozygotes) and populations ...
Clustering short time series gene expression data
Clustering short time series gene expression data

... • If the above distance is minimized by h>1 model profiles then we assign g to all of these profiles, but weight the assignment in the counts as 1/h. • t(mi) : the number of gene assigned to the mi model profile ...
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trait

IJBT 10(2) 178-182
IJBT 10(2) 178-182

... present study, out of 24 Murrah bulls studied, 2 bulls (Mu-5083 and Mu-5525) found as type III genotype, were the mutant type. The association study between the genotypic variants in Murrah with per cent individual motility as well as conception rates (CR %) was not found significant. Performance re ...
Dihybrid Punnett Squares
Dihybrid Punnett Squares

... What are the possible genotypes and phenotypes of the children of parents that are heterozygous for round eyes with a blue body and purebred for round eyes and hybrid for a yellow body? ...
Kinetic MoDiversity of Hydrocarbon-Related Catabolic Genes in Oil
Kinetic MoDiversity of Hydrocarbon-Related Catabolic Genes in Oil

... database under the accession numbers: alk - JX171303-JX171314, ARHD - JX512729-JX512738 and bamA – JX512739-JX512747. It is worth to note that only one representative sequence of each OPF was deposited at the database. ...
Genome-wide Regulatory Complexity in Yeast Promoters
Genome-wide Regulatory Complexity in Yeast Promoters

... involved in the energy generation and steroid synthesis pathways, suggesting that these types of genes have unusually complex regulation. • The genes with the strongest protein sequence conservation were not always those having the longest HCR lengths, Catalysis, Basic Biosynthesis, and Ribosomal Ge ...
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Human Chromosomes
Human Chromosomes

...  A research project to sequence (identify in order) ...
Genetics Part 1
Genetics Part 1

... capital letter P and the recessive allele with a lower case p. ...
What_Is_Ontology_Mia.. - Buffalo Ontology Site
What_Is_Ontology_Mia.. - Buffalo Ontology Site

... three-dimensional RNA structures ...
Mendelian Genetics
Mendelian Genetics

... Revision – The Basics ...
The Pleiotropy Problem for Evolution
The Pleiotropy Problem for Evolution

... are redundant (meaning different cytokines may have the same effect) and yet can have multiple effects on the same cell in different circumstances. This fact again illustrates that single mutations, although beneficial, often have a wide variety of results, some quite negative, on other systems. A si ...
Sur-8(lf)
Sur-8(lf)

... the serine/threonine kinase activity of raf-1 through tyrosine phosphorylation by the PDGF receptor We have examined the interaction between the serine/threonine kinase protooncogene product Raf-1 and the tyrosine kinase PDGF beta-receptor. Raf-1 tyrosine phosphorylation and kinase activity were inc ...
Hands-on Lab using mboost: Modeling Breast Cancer Gene
Hands-on Lab using mboost: Modeling Breast Cancer Gene

... in the test sample and the CoxPH()@risk function. (Note: The partial log likelihood of the observations in the test sample will be used as a measure of prediction accuracy.) 5. Prediction rule 2. To evaluate clinical relevance, it is of interest to investigate whether gene expression data improve e ...
Gene Section RBL2 (retinoblastoma-like 2) Atlas of Genetics and Cytogenetics
Gene Section RBL2 (retinoblastoma-like 2) Atlas of Genetics and Cytogenetics

Lecture 3 - Tresch Group
Lecture 3 - Tresch Group

... From the data alone we can not decide which genes are important for the diagnosis, nor can we give a reliable diagnosis for a new patient This has little to do medicine. It is a geometrical problem. ...
S1-1-13 - The Big Gamble - Lesson
S1-1-13 - The Big Gamble - Lesson

... fibrosis gene can be found. If a person has one “regular” gene and one gene for cystic fibrosis they will not develop the disease. If a person has two genes for cystic fibrosis they will develop the disease. Even though both of these combinations contain the cystic fibrosis gene, only the person wit ...
Embryonic growth and the evolution of the mammalian Y
Embryonic growth and the evolution of the mammalian Y

... monogamous, a Y-linked sequence that can positively alter any of the above parameters could spread in a population even if it harms the prospects of other embryos. Such a selfish Y-linked gene could act as a sex ratio distorter. In contrast to autosomal imprinted loci, the patrilineal inheritance of ...
Titel: Functional replacement of Gfi1 deficiency by Gfi1b obviously
Titel: Functional replacement of Gfi1 deficiency by Gfi1b obviously

... Generation of Gfi:Gfi1b and Gfi1:Gfi1P2A knock-in mice Both knock-in mice were generated by modifying the previously described Gfi1:GFP knockin construct (Yücel et al., 2004). The constructs were transfected in R1 ES cells and selection with G418 and ganciclovir was performed. Mice were held under s ...
extracellular polysaccharide colanic acid. cluster responsible for
extracellular polysaccharide colanic acid. cluster responsible for

... cluster (81) (Fig. 2). This segment of DNA is 23 kb in length (Fig. 2). The promoter region is followed after about 60 bp by a JUMPstart sequence (81a), a highly conserved 39-bp element which is found upstream of many polysaccharide gene clusters (30). There are then 21 open reading frames all in th ...
Non-Mendelian Inheritance | Principles of Biology from Nature
Non-Mendelian Inheritance | Principles of Biology from Nature

... heterozygous Tay-Sachs carriers, the functional allele in carriers produces some enzyme but not as much as homozygous non-carriers make, similar to the way the red allele produces enough red pigment in heterozygous snapdragons to make them pink. Most genes have multiple phenotypic effects. Genes cod ...
Cloning and characterization of a gene coding for a hydrophobin Fv
Cloning and characterization of a gene coding for a hydrophobin Fv

... fruiting bodies. Hence, the fv-hyd1 gene is a novel hydrophobin gene closely associated with the fruiting process. Southern blot analysis revealed that the fv-hyd1 gene is a single-copy gene in the genome of F. velutipes (Fig. 5). We could detect faint cross-hybridized signals that might correspond ...
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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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