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REVIEW ARTICLE Gene cassettes
REVIEW ARTICLE Gene cassettes

... Hall, 1992b). Most 59-base elements have a central axis of symmetry as the consensus regions are imperfect inverted repeats. All 59-base elements also contain inverted repeat sequences in their central region, and it is this region that varies in length. Within the 59-base element family, a few grou ...
Shedding Genomic Ballast: Extensive Parallel Loss of Ancestral
Shedding Genomic Ballast: Extensive Parallel Loss of Ancestral

... contrary to the Ecdysozoa hypothesis, which proposes that nematodes and arthropods constitute a clade (Aguinaldo et al. 1997). However, the same pattern was seen in extensive phylogenetic analyses based on protein sequences (Blair et al. 2002), as well as a previous analysis based on the presence/ab ...
Purine Biosynthesis. Big in Cell Division, Even
Purine Biosynthesis. Big in Cell Division, Even

... purine pathway in plants was based on information gained from other organisms. The pathway, first characterized in prokaryotes and avian liver, involves 10 enzymatic steps (Fig. 1) to synthesize IMP (the first product with a complete purine ring) from PRPP (Zalkin and Dixon, 1992). AMP and GMP are s ...
Letter The Evolution of Male–Female Sexual
Letter The Evolution of Male–Female Sexual

... (Umen 2011). A recent comparative study of MT from an oogamous volvocine species, Volvox carteri, with MT from an isogamous species, Chlamydomonas reinhardtii, revealed major differences in the size- and sex-based differentiation of MT genes (Ferris et al. 2010). Volvox MT was found to be about five ...
nsfrui2004 - Mount Holyoke College
nsfrui2004 - Mount Holyoke College

... processes. Here I describe a plan to continue this line of research. These hypothesis-driven experiments are perfect for training undergraduates in the practice of science, and undergraduate students will be intimately involved in each part of this research plan. In addition, this proposal describes ...
Database of cattle candidate genes and genetic markers for
Database of cattle candidate genes and genetic markers for

... well as development and function of endocrine system. Eight loci are involved in cell mediated immune response and structure and development of lymphoid tissue and the other eight are involved in cellular development, movement and cancer. Three loci were associated with organ morphology, development ...
Chapter 12 Chromosomal Patterns of Inheritance
Chapter 12 Chromosomal Patterns of Inheritance

... the sex chromosomes. This pair determines the sex of the new individual. The father can contribute an X chromosome or a Y chromosome to his offspring, while the mother can only contribute an X chromosome. Therefore, the sex of the offspring is determined by the genetic contribution of the father. Th ...
The Making of the Fittest: Evolving Switches, Evolving Bodies
The Making of the Fittest: Evolving Switches, Evolving Bodies

... Key Points to Emphasize: • Students may wonder why Pitx1 is expressed in such diverse tissues. This is because the Pitx1 gene contains multiple regulatory switches that allow for transcription of that gene in multiple tissues. The expression of Pitx1 is important in various tissues because the Pitx1 ...
MS-SCI-LS-Unit 2 -- Chapter 6- Modern Genetics
MS-SCI-LS-Unit 2 -- Chapter 6- Modern Genetics

... gene can be involved. Sometimes, a single gene can affect more than one trait. Or, all of a gene's effects may not be visible or even known. Because patterns of inheritance can be complicated, there is not always a one-to-one correspondence between trait and gene. In this section, you will learn abo ...
PDF
PDF

... directs a Cas9 nuclease to a specific genomic locus. Cas9 cleaves the gene of interest and creates a double­ stranded break (DSB) in the DNA, which can be repaired by non­homologous end joining (NHEJ). As NHEJ is an error­prone DNA repair process, insertions and deletions (indels) are often introduc ...
Supplemental File S9. Homologous Chromosomes
Supplemental File S9. Homologous Chromosomes

... 4. Do the human X and Y chromosomes each have the same number of genes? Answer: No; the human X chromosome contains many more genes than the human Y chromosome. 5. How is sex determined in humans? Answer: Humans have a genetic (or chromosomal) system of sex determination. That is, sex determination ...
Draft-press-release-for-SA-press
Draft-press-release-for-SA-press

... four-legged amphibious creatures to climb out of the water and up on to land, but until now, researchers could not determine which of the two is the more likely candidate. In addition to sequencing the full genome – nearly 3 billion “letters” of DNA – from the coelacanth, the researchers also looked ...
−Table of Contents
−Table of Contents

... An identification of the unknown band 1 area was attempted using the uv-vis spectrum obtained. The unknown spectrum did not match up well with that of chalcone because it contained a peak around 270nm that chalcone lacks. The peaks of the unknown at 270nm and 362nm suggest that the unknown is a flav ...
Bioinformatics Supplement - Bio-Rad
Bioinformatics Supplement - Bio-Rad

... perform the same function as the protein produced by the daf-18 gene? We can answer these questions by delving into data stored in large genetics databases like those maintained by the National Center for Biotechnology Information (NCBI), such as GenBank. By performing a homology search — a search i ...
Gene interactions
Gene interactions

... The four common blood groups of the human ABO blood group system are determined by three alleles: A, B, and O (also represented in some texts as IA, IB, IO or just i). This is an example of a multiple allele system for a gene. ABO antigens consist of sugars attached to the red blood cell surface. Th ...
anterior olfactory nucleus (aon) - Dashboard
anterior olfactory nucleus (aon) - Dashboard

... visually (lower value = the correlation value of the 25th ranked substructure reported on the previous page) using the “jet” color scale at rostrocaudal levels throughout the brain. ...
Meiosis II
Meiosis II

... http://www.ahsd.org/science/moss/AP%20Biology/meiosisnotes%20and%20Sordaria%20Lab.htm ...
Document
Document

... 1. Do we need a relationship in OBO-REL to define homology? This is a symmetric relation between sisters and it is the relationship that requires evidence and attribution. 2. Should homology assignments be a top-down or bottom up approach?eg. Pairs of taxa vs. CARO-centric assignments? RE:domain exp ...
No Slide Title
No Slide Title

... • Bruce Blumberg ([email protected]) – 4103 Nat Sci 2 - office hours Tu, Th 3:30-5:00 (or by appointment) ...
Reciprocal products of chromosomal translocations in human
Reciprocal products of chromosomal translocations in human

... and translocations, with translocations being by far the most frequent [1,2]. In lymphoid leukaemias and lymphomas, chromosomal translocations frequently lead to the transcriptional activation of proto-oncogenes by bringing their coding regions in the vicinity of immunoglobulin or T-cell receptor ge ...
Chapter 6A
Chapter 6A

... collection of exons within a larger gene. The coding regions for domains can be spliced in or out of the primary transcript by the process of alternative splicing. The resulting mRNAs encode different forms of the protein, known as isoforms. Alternative splicing is an important method for regulation ...
Gene Section SSX2 (synovial sarcoma, X breakpoint 2) in Oncology and Haematology
Gene Section SSX2 (synovial sarcoma, X breakpoint 2) in Oncology and Haematology

... levels in the developing and normal adult testis (Apale and B spermatogonia) (Chen et al., 2011; Lim et al., 2011), and less abundantly in the thyroid gland (Crew et al., 1995). Its structural analysis (Lim et al., 1998) revealed two functional domains; an N-terminal region (amino acids 20-83) homol ...
Gene–Nutrition Interaction in Human Performance and Exercise
Gene–Nutrition Interaction in Human Performance and Exercise

... remained highly concordant throughout a lifetime, physical activity level did not, suggesting that environmental factors rather than genetic factors are more important in determining an individual’s propensity to be active in later life. Recently, Maia et al.4 studied 411 Portuguese twins of differe ...
Download: Genes, Genomics, and Chromosomes
Download: Genes, Genomics, and Chromosomes

Editorial Comment Will Gene Markers Predict Hypertension?
Editorial Comment Will Gene Markers Predict Hypertension?

... such as HLA-B27 with ankylosing spondylitis, shows exactly the same gene marker polymorphism in diseased persons in many different families. Obtaining the data from family members for linkage studies is often more difficult than obtaining marker and disease status on many persons sampled from the ge ...
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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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