TEV_v7_BY
... We first predicted 103,798 TEVs (28,951 SINEs, 40,074 LINEs and 34,773 ERVs) among the 17 mouse strains, an order of magnitude higher than previous studies 14,16. We employed two approaches to TEV discovery, SVMerge which combines the results of four methods of structural variation prediction 17, an ...
... We first predicted 103,798 TEVs (28,951 SINEs, 40,074 LINEs and 34,773 ERVs) among the 17 mouse strains, an order of magnitude higher than previous studies 14,16. We employed two approaches to TEV discovery, SVMerge which combines the results of four methods of structural variation prediction 17, an ...
Organization of Project
... A bacterium typically needs to replicate its genome (say 3 million nucleotides) in a leisurely several hours, before the next cell division. Phages are often under much greater time pressure. For example, in the case of phage T4: 300 copies x 170,000 nt per copy = 51 million nt in 30 minutes! ...
... A bacterium typically needs to replicate its genome (say 3 million nucleotides) in a leisurely several hours, before the next cell division. Phages are often under much greater time pressure. For example, in the case of phage T4: 300 copies x 170,000 nt per copy = 51 million nt in 30 minutes! ...
Nitrogen fixation:
... From the comparative analysis of 16S rRNA genes, relationships of bacteria to known fixers have been revealed. For example, strains of sewage water Zooglea ramigera were found to be similar to the rhizobia group (Rosselló-Mora et al., 1993); Pseudoaminobacter, Chelatobacter, and Aminobacter with imp ...
... From the comparative analysis of 16S rRNA genes, relationships of bacteria to known fixers have been revealed. For example, strains of sewage water Zooglea ramigera were found to be similar to the rhizobia group (Rosselló-Mora et al., 1993); Pseudoaminobacter, Chelatobacter, and Aminobacter with imp ...
Practice guidelines for the Interpretation and Reporting of
... significance and that the depth of conservation is recorded in any documentation relating to the analysis, although it doesn’t need to be included in the report. The documentation should outline which species and/or orthologues were included in the comparison and what comparison method and parameter ...
... significance and that the depth of conservation is recorded in any documentation relating to the analysis, although it doesn’t need to be included in the report. The documentation should outline which species and/or orthologues were included in the comparison and what comparison method and parameter ...
Studying copy number variations using a nanofluidic platform
... this variation is important not only to understand the full spectrum of human genetic variation but also to assess the significance of such variation in disease-association studies. The first human CNV map was constructed from a study of 270 normal individuals with a total of 1447 CNV regions in the w ...
... this variation is important not only to understand the full spectrum of human genetic variation but also to assess the significance of such variation in disease-association studies. The first human CNV map was constructed from a study of 270 normal individuals with a total of 1447 CNV regions in the w ...
genotype and gene expression in wild baboons Social environment
... genetic reaction norms. Specifically, we know little about whether and to what extent the social environment, similarly to other environmental effects, can produce norms of reaction that differ for individuals of different genotypes (i.e. gene– environment interactions, GEIs [26]). Viewed from a com ...
... genetic reaction norms. Specifically, we know little about whether and to what extent the social environment, similarly to other environmental effects, can produce norms of reaction that differ for individuals of different genotypes (i.e. gene– environment interactions, GEIs [26]). Viewed from a com ...
The MAOA Gene Predicts Credit Card Debt ∗ London School of Economics
... (Fowler, Baker & Dawes 2008), and even happiness levels (Weiss, Bates & Luciano 2008). Although twin studies are an important first step in establishing the role of genes for a particular behavior like holding credit card debt, they do not identify the specific genes involved. But the rising availab ...
... (Fowler, Baker & Dawes 2008), and even happiness levels (Weiss, Bates & Luciano 2008). Although twin studies are an important first step in establishing the role of genes for a particular behavior like holding credit card debt, they do not identify the specific genes involved. But the rising availab ...
Document
... promoter downstream from it, because reading through the downstream promoter prevents the necessary transcription factors from binding to it. The RNA transcribed from the upstream promoter has no coding function. ...
... promoter downstream from it, because reading through the downstream promoter prevents the necessary transcription factors from binding to it. The RNA transcribed from the upstream promoter has no coding function. ...
Genes for two multicopper proteins required for Fe(III) oxide
... Childers et al., 2002; Mehta et al., 2006; Reguera et al., 2005). One of these, designated outer-membrane protein B (OmpB), is a putative multicopper protein (Mehta et al., 2006) that is loosely associated with the outer cell surface (Qian et al., 2007), and is required for the reduction of insolubl ...
... Childers et al., 2002; Mehta et al., 2006; Reguera et al., 2005). One of these, designated outer-membrane protein B (OmpB), is a putative multicopper protein (Mehta et al., 2006) that is loosely associated with the outer cell surface (Qian et al., 2007), and is required for the reduction of insolubl ...
Temporal genomic evolution of bird sex chromosomes
... and Z chromosomes. We focus all our analyses throughout this study between these two sets of chromosomes of a similar size, because microchromosomes have very different genomic features (i.e., recombination rate, gene density, GC content, repeat content etc.) compared to others [50], which influence ...
... and Z chromosomes. We focus all our analyses throughout this study between these two sets of chromosomes of a similar size, because microchromosomes have very different genomic features (i.e., recombination rate, gene density, GC content, repeat content etc.) compared to others [50], which influence ...
Sulphur Metabolism on the Anaerobic Earth Dr
... the role of the third gene that they discovered by comparing the genomes of methanogens and other Archaea. In M. acetivorans this gene encodes the previously unstudied protein MA1715. By comparing the sequence of MA1715 with that of its counterparts – homologues – in other methanogens, they found th ...
... the role of the third gene that they discovered by comparing the genomes of methanogens and other Archaea. In M. acetivorans this gene encodes the previously unstudied protein MA1715. By comparing the sequence of MA1715 with that of its counterparts – homologues – in other methanogens, they found th ...
Recruitment of 5! Hoxa genes in the allantois is
... transient and by E9.5 the extra-embryonic expression of Hoxa10 and Hoxa11 is only detected in the maternal part (decidua) and not in the labyrinth (Fig. 2 and supplementary material Fig. S1). 5⬘Hoxa genes are expressed in progenitors of the labyrinthine vasculature The early and transient co-expres ...
... transient and by E9.5 the extra-embryonic expression of Hoxa10 and Hoxa11 is only detected in the maternal part (decidua) and not in the labyrinth (Fig. 2 and supplementary material Fig. S1). 5⬘Hoxa genes are expressed in progenitors of the labyrinthine vasculature The early and transient co-expres ...
143KB - NZQA
... chromosomes/ unique gametes and does not produce new information. ACHIEVEMENT WITH EXCELLENCE In addition to the skills and knowledge required for the award of Achievement with Merit, candidates who were awarded Achievement with Excellence commonly: • compared independent assortment and crossing ove ...
... chromosomes/ unique gametes and does not produce new information. ACHIEVEMENT WITH EXCELLENCE In addition to the skills and knowledge required for the award of Achievement with Merit, candidates who were awarded Achievement with Excellence commonly: • compared independent assortment and crossing ove ...
Ch 21
... – The Cancer Genome Atlas project is currently monitoring 2,000 genes in cancer cells for changes due to mutations and rearrangements – Treatment of cancers and other diseases can be individually tailored following analysis of gene expression patterns in a patient – In future, DNA sequencing may hig ...
... – The Cancer Genome Atlas project is currently monitoring 2,000 genes in cancer cells for changes due to mutations and rearrangements – Treatment of cancers and other diseases can be individually tailored following analysis of gene expression patterns in a patient – In future, DNA sequencing may hig ...
The Differential Killing of Genes by Inversions in Prokaryotic Genomes
... genomes from Clusters of Orthologous Groups (COGs) downloaded 20 January 2000 from ftp://www.ncbi.nlm.nih.gov/pub/COG. COGs contain proteins which are supposed to have evolved from one ancestral protein (Koonin et al. 1998; Tatusov et al. 2000). In the construction of COGs the authors have used the ...
... genomes from Clusters of Orthologous Groups (COGs) downloaded 20 January 2000 from ftp://www.ncbi.nlm.nih.gov/pub/COG. COGs contain proteins which are supposed to have evolved from one ancestral protein (Koonin et al. 1998; Tatusov et al. 2000). In the construction of COGs the authors have used the ...
NItric Oxide and Prostaglandins: Mediators of Pathogenesis in
... • Heterozygous state (SC) = protection from malaria • Mechanism unknown but red blood cells from (SC) individuals have reduced parasite growth and impaired invasion under low O2 tension • In addition to red cell abnormalities, there are many other genetic changes…….. ...
... • Heterozygous state (SC) = protection from malaria • Mechanism unknown but red blood cells from (SC) individuals have reduced parasite growth and impaired invasion under low O2 tension • In addition to red cell abnormalities, there are many other genetic changes…….. ...
Chapter 21
... • Errors in meiosis can result in an exon being duplicated on one chromosome and deleted from the homologous chromosome • In exon shuffling, errors in meiotic recombination lead to some mixing and matching of exons, either within a gene or between two nonallelic genes Copyright © 2008 Pearson Educat ...
... • Errors in meiosis can result in an exon being duplicated on one chromosome and deleted from the homologous chromosome • In exon shuffling, errors in meiotic recombination lead to some mixing and matching of exons, either within a gene or between two nonallelic genes Copyright © 2008 Pearson Educat ...
Insights into three whole-genome duplications gleaned
... With the discovery of at least three successive whole-genome duplications (WGDs) in the history of the P. tetraurelia lineage (AURY et al. 2006), there is renewed interest in the evolution and genetics of Paramecium. WGDs can be found in the ancestry of many model organisms, including zebrafish (POS ...
... With the discovery of at least three successive whole-genome duplications (WGDs) in the history of the P. tetraurelia lineage (AURY et al. 2006), there is renewed interest in the evolution and genetics of Paramecium. WGDs can be found in the ancestry of many model organisms, including zebrafish (POS ...
Chapter 21 Genomes
... – The Cancer Genome Atlas project is currently monitoring 2,000 genes in cancer cells for changes due to mutations and rearrangements – Treatment of cancers and other diseases can be individually tailored following analysis of gene expression patterns in a patient – In future, DNA sequencing may hig ...
... – The Cancer Genome Atlas project is currently monitoring 2,000 genes in cancer cells for changes due to mutations and rearrangements – Treatment of cancers and other diseases can be individually tailored following analysis of gene expression patterns in a patient – In future, DNA sequencing may hig ...
Section D - Prokaryotic and Eukaryotic Chromosome Structure
... Some cloning vector ：The pUC vectors have a promoter (lac) adjacent to the site of insertion of a cloned fragment, such a promoter could be used to transcribe the inserted DNA, either to produce an RNA transcript in vitro (used as a hybridization probe), or to express the protein product of a gene. ...
... Some cloning vector ：The pUC vectors have a promoter (lac) adjacent to the site of insertion of a cloned fragment, such a promoter could be used to transcribe the inserted DNA, either to produce an RNA transcript in vitro (used as a hybridization probe), or to express the protein product of a gene. ...
Monday October 24 lecture slides (week 4)
... Hypothesis: A tentative explanation (best guess) about how a natural process works or why it is the way it is – Based on previous studies and/or observations – Is valid under a broad set of conditions – Leads to testable predictions (it is possible to gather information to determine whether the e ...
... Hypothesis: A tentative explanation (best guess) about how a natural process works or why it is the way it is – Based on previous studies and/or observations – Is valid under a broad set of conditions – Leads to testable predictions (it is possible to gather information to determine whether the e ...
hindlimb - bthsresearch
... engineered to express a gene of interest • The embryo can then be injected with the virus at an early stage • As virus spreads through the developing tissue, gene expression is turned on • In this way we can express genes ectopically in chick tissue – Like a gain of function mutation in a mouse, but ...
... engineered to express a gene of interest • The embryo can then be injected with the virus at an early stage • As virus spreads through the developing tissue, gene expression is turned on • In this way we can express genes ectopically in chick tissue – Like a gain of function mutation in a mouse, but ...
1.1 Genetic terms you should know and understand Mendelian
... observed frequencies are 33% and 50% in the two families which is not statistically significant for this small sample size. Therefore, this model fits the data. However, this model assumes that three non-blood relatives all carry the abnormal gene (1, 2, and 3). If we assume that the abnormality is ...
... observed frequencies are 33% and 50% in the two families which is not statistically significant for this small sample size. Therefore, this model fits the data. However, this model assumes that three non-blood relatives all carry the abnormal gene (1, 2, and 3). If we assume that the abnormality is ...
Gene expression profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.