A series of vectors for fungal transformation
... enzyme involved in isoleucine and valine synthesis. Sulfonylureas (specifically chlorimuron ethyl, the active ingredient of the herbicide Classicreg.) inhibit acetolactate synthase. The sulfonylurea resistant allele of M. grisea ILV1 has been subcloned as a 2.8 kb fragment and modified by the elimin ...
... enzyme involved in isoleucine and valine synthesis. Sulfonylureas (specifically chlorimuron ethyl, the active ingredient of the herbicide Classicreg.) inhibit acetolactate synthase. The sulfonylurea resistant allele of M. grisea ILV1 has been subcloned as a 2.8 kb fragment and modified by the elimin ...
Threshold phenomena versus cell heredity in the
... As judged by eye, there is some resemblance between the chimeras and some of the phenotypes discussed in this paper (brindled, flecked), but closer inspection immediately reveals consistent differences. For instance, according to both Mintz (1967) and Mystkowska & Tarkowski (1968), the tails of chim ...
... As judged by eye, there is some resemblance between the chimeras and some of the phenotypes discussed in this paper (brindled, flecked), but closer inspection immediately reveals consistent differences. For instance, according to both Mintz (1967) and Mystkowska & Tarkowski (1968), the tails of chim ...
Hemoglobin research and the origins of molecular
... Roughton, and others in the last century and has been reviewed in detail.10,11 More recently elucidated was how this finely tuned system is regulated via heterotropic interactions with other molecules, such as protons, anions, and bisphosphosphoglyceric acid (2,3 BPG or, in the older convention, 2,3 ...
... Roughton, and others in the last century and has been reviewed in detail.10,11 More recently elucidated was how this finely tuned system is regulated via heterotropic interactions with other molecules, such as protons, anions, and bisphosphosphoglyceric acid (2,3 BPG or, in the older convention, 2,3 ...
Comparative Analysis of Parallel Gene Transfer Operators in the
... Based on the test calculations it can be concluded that the three modified gene transfer operators are applicable in real life problems. On the contrary, the acceleration of the optimization using the original gene transfer is the consequence of bacterial mutation only. It is not recommended to use ...
... Based on the test calculations it can be concluded that the three modified gene transfer operators are applicable in real life problems. On the contrary, the acceleration of the optimization using the original gene transfer is the consequence of bacterial mutation only. It is not recommended to use ...
STPM 2011 - Soalan-Percubaan-STPM
... Multiple alleles are A both alleles in a heterozygote are dominant and fully expressed in phenotype B both alleles that give partial influence in heterozygous form C more than two alternative forms a particular gene that occupy the same locus D genes that results in the death of an organism. ...
... Multiple alleles are A both alleles in a heterozygote are dominant and fully expressed in phenotype B both alleles that give partial influence in heterozygous form C more than two alternative forms a particular gene that occupy the same locus D genes that results in the death of an organism. ...
Biology Chapter 11: Homework Hmwrk 11
... 2. Who was Gregor Mendel and what did he study? 3. What is a trait? List all of the traits that Mendel looked at. 4. Define genes and alleles. 5. Draw out your family tree starting with your grandparents. Label the P generation, the F1 generation and the F2 generation. Hmwrk 11-2 1. Define probabili ...
... 2. Who was Gregor Mendel and what did he study? 3. What is a trait? List all of the traits that Mendel looked at. 4. Define genes and alleles. 5. Draw out your family tree starting with your grandparents. Label the P generation, the F1 generation and the F2 generation. Hmwrk 11-2 1. Define probabili ...
Warren, ST and Nelson, DL: Trinucleotide repeat expansions in neurological disease. Current Opinion in Neurobiology 3:752-759 (1993).
... For decades, mutational mechanisms that lead to human genetic disease have followed rules and examples set forth in model systems such as Drosophila and yeast. In recent years, however, new mechanisms responsible for genetic disease have emerged where little or no precedent had been established in o ...
... For decades, mutational mechanisms that lead to human genetic disease have followed rules and examples set forth in model systems such as Drosophila and yeast. In recent years, however, new mechanisms responsible for genetic disease have emerged where little or no precedent had been established in o ...
Constitutive expression of catABC genes in the aniline
... The aniline-assimilating bacterium Rhodococcus sp. AN-22 was found to constitutively synthesize CatB (cis,cis-muconate cycloisomerase) and CatC (muconolactone isomerase) in its cells growing on non-aromatic substrates, in addition to the previously reported CatA (catechol 1,2-dioxygenase). The bacte ...
... The aniline-assimilating bacterium Rhodococcus sp. AN-22 was found to constitutively synthesize CatB (cis,cis-muconate cycloisomerase) and CatC (muconolactone isomerase) in its cells growing on non-aromatic substrates, in addition to the previously reported CatA (catechol 1,2-dioxygenase). The bacte ...
Journal of Bacteriology
... subsp. nigra, whereas inoculation with heterologous Rhizobium strains results in exudates with nod geneinducing activity comparable to that of uninfected plants. Ini can be demonstrated by using either of the isogenic indicator strains containing an inducible nod promoter fused to the Escherichia co ...
... subsp. nigra, whereas inoculation with heterologous Rhizobium strains results in exudates with nod geneinducing activity comparable to that of uninfected plants. Ini can be demonstrated by using either of the isogenic indicator strains containing an inducible nod promoter fused to the Escherichia co ...
1_Standards for the Safety Assessment of Genetically Modified Foods (Seed Plants).pdf
... plants. For instance, inserting a DNA sequence not only confers a specific trait to the plant (intended effect) but also may also confer additional traits or eliminate or modify the existing traits of the host (unintended effects). These unintended effects may be harmful, beneficial or neither harmf ...
... plants. For instance, inserting a DNA sequence not only confers a specific trait to the plant (intended effect) but also may also confer additional traits or eliminate or modify the existing traits of the host (unintended effects). These unintended effects may be harmful, beneficial or neither harmf ...
genetic and metabolic testing of children with global developmental
... is important. Because of improved technologies, the available tests are much better at detecting the cause of GDD than tests available just a short time ago. However, a positive test result alone is not enough to make a clear diagnosis. Other factors are also important to consider. For example, phys ...
... is important. Because of improved technologies, the available tests are much better at detecting the cause of GDD than tests available just a short time ago. However, a positive test result alone is not enough to make a clear diagnosis. Other factors are also important to consider. For example, phys ...
Fra1 is essential for placental development
... their growth retardation and lethality. Importantly, when the placental defect was rescued by injection of Fra1−/− ES cells into tetraploid wild-type blastocysts, Fra1−/− pups were obtained that were no longer growth retarded and survived up to 2 days after birth without apparent phenotypic defects. ...
... their growth retardation and lethality. Importantly, when the placental defect was rescued by injection of Fra1−/− ES cells into tetraploid wild-type blastocysts, Fra1−/− pups were obtained that were no longer growth retarded and survived up to 2 days after birth without apparent phenotypic defects. ...
Chapter 18
... We observed the switch to be caused by environmental factors like radiation or certain chemicals causing DNA damage, which would promote the lytic phase as the bacterial cell will likely die soon and the phage needs to get out quick. In addition, lytic is favored when nutrients are plentiful allowin ...
... We observed the switch to be caused by environmental factors like radiation or certain chemicals causing DNA damage, which would promote the lytic phase as the bacterial cell will likely die soon and the phage needs to get out quick. In addition, lytic is favored when nutrients are plentiful allowin ...
Recent highlights of the China Rice Functional Genomics Program
... functional genomics is for genetic improvement of rice by a transgenic approach. To build up a pipeline from genes to traits, we have developed a platform for genetic improvements of key agronomic traits including a robust transformation technology and controllable expression systems. This can be il ...
... functional genomics is for genetic improvement of rice by a transgenic approach. To build up a pipeline from genes to traits, we have developed a platform for genetic improvements of key agronomic traits including a robust transformation technology and controllable expression systems. This can be il ...
Polygenic inheritance of fruit size in red pepper
... two of each of thirty progenies, would still constitute a si&all sample, and because the two plants were samples of a segregating population, the effect of confounding would still be large. ...
... two of each of thirty progenies, would still constitute a si&all sample, and because the two plants were samples of a segregating population, the effect of confounding would still be large. ...
Chapter 18
... What causes a temperate phage like lambda to switch from lysogenic to lytic? We observed the switch to be caused by environmental factors like radiation or certain chemicals causing DNA damage, which would promote the lytic phase as the bacterial cell will likely die soon and the phage needs to get ...
... What causes a temperate phage like lambda to switch from lysogenic to lytic? We observed the switch to be caused by environmental factors like radiation or certain chemicals causing DNA damage, which would promote the lytic phase as the bacterial cell will likely die soon and the phage needs to get ...
HapTree-X: An integrative Bayesian framework for haplotype
... Identifying phase information is biomedically important due to the association of complex haplotype effects, such as compound heterozygosity, with disease. As recent next-generation sequencing (NGS) technologies provide more read sequences, the use of diverse sequencing datasets for haplotype phasin ...
... Identifying phase information is biomedically important due to the association of complex haplotype effects, such as compound heterozygosity, with disease. As recent next-generation sequencing (NGS) technologies provide more read sequences, the use of diverse sequencing datasets for haplotype phasin ...
11–3 Exploring Mendelian Genetics
... Multiple Alleles Many genes have more than two alleles and are therefore said to have multiple alleles. This does not mean that an individual can have more than two alleles. It only means that more than two possible alleles exist in a population. One of the best-known examples is coat color in rabbi ...
... Multiple Alleles Many genes have more than two alleles and are therefore said to have multiple alleles. This does not mean that an individual can have more than two alleles. It only means that more than two possible alleles exist in a population. One of the best-known examples is coat color in rabbi ...
Extensions and Modifications of Basic Principles
... CFTR are codominant, because both alleles are expressed in the heterozygote. However, because one normal allele produces enough functional CFTR protein to allow normal chloride transport, the heterozygote exhibits no adverse effects, and the mutated CFTR allele appears to be recessive at the physiol ...
... CFTR are codominant, because both alleles are expressed in the heterozygote. However, because one normal allele produces enough functional CFTR protein to allow normal chloride transport, the heterozygote exhibits no adverse effects, and the mutated CFTR allele appears to be recessive at the physiol ...
Mouse genetics provides insight into folliculogenesis, fertilization
... Oct4 expression faithfully follows the germ cell lineage. Oct4 transcripts are ®rst detected in the epiblast during gastrulation (~E6.5) and later became restricted to PCG located in the extraembryonic mesoderm (Yeom et al., 1996). The germ cells subsequently enter the embryo proper and migrate to t ...
... Oct4 expression faithfully follows the germ cell lineage. Oct4 transcripts are ®rst detected in the epiblast during gastrulation (~E6.5) and later became restricted to PCG located in the extraembryonic mesoderm (Yeom et al., 1996). The germ cells subsequently enter the embryo proper and migrate to t ...
Risks from GMOs due to Horizontal Gene Transfer
... HGT has been recorded in a number of environmental situations such as soil, seawater, freshwater, animal and industrial waste products, plant surfaces, animal intestines, human saliva and food products (Bushman, 2002; Davison, 1999; Lilley et al., 2003; van den Eede et al., 2004; Wolska, 2003). Some ...
... HGT has been recorded in a number of environmental situations such as soil, seawater, freshwater, animal and industrial waste products, plant surfaces, animal intestines, human saliva and food products (Bushman, 2002; Davison, 1999; Lilley et al., 2003; van den Eede et al., 2004; Wolska, 2003). Some ...
Is trehalose-6-phosphate a regulator of sugar metabolism in plants?
... trehalose led to the suggestion that the majority of higher plants had lost the ability to produce it (Crowe et al., 1992). However, the activity of trehalase, an enzyme responsible for the breakdown of trehalose to glucose, is present in numerous plants (MuÈller et al., 1995). By applying an inhibi ...
... trehalose led to the suggestion that the majority of higher plants had lost the ability to produce it (Crowe et al., 1992). However, the activity of trehalase, an enzyme responsible for the breakdown of trehalose to glucose, is present in numerous plants (MuÈller et al., 1995). By applying an inhibi ...
Gene expression profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.