acid-base disturbances
... Hypotonic hyponatremia most common scenario; true excess of free H2O relative to Na Hypertonic hyponatremia: excess of another effective osmole (eg, glc, mannitol) that draws H2O intravascularly; each 100 mg/dL ↑ glc >100 mg/dL → ↓ [Na] by 2.4 mEq/L Isotonic hyponatremia: rare lab artifact from hype ...
... Hypotonic hyponatremia most common scenario; true excess of free H2O relative to Na Hypertonic hyponatremia: excess of another effective osmole (eg, glc, mannitol) that draws H2O intravascularly; each 100 mg/dL ↑ glc >100 mg/dL → ↓ [Na] by 2.4 mEq/L Isotonic hyponatremia: rare lab artifact from hype ...
Nutritional Consequences of Small Intestinal Bacterial Overgrowth
... with overall small bowel length (7) and the presence of ileal peristalsis, as the primary factors responsible for controlling the number of bacteria in the small bowel (22). Finally, intestinal mucus normally traps bacteria intraluminally. As a result, in some instances, excess bacterial counts may ...
... with overall small bowel length (7) and the presence of ileal peristalsis, as the primary factors responsible for controlling the number of bacteria in the small bowel (22). Finally, intestinal mucus normally traps bacteria intraluminally. As a result, in some instances, excess bacterial counts may ...
The phenotypes of bipolar disorder: relevance for genetic
... Refining the phenotype Many psychiatric disorders are heterogeneous. Mapping genes in more homogeneous subgroups has been already effective in other complex traits where such groups were defined by age of onset, biological markers, or clinical characteristics.43–50 In a comprehensive review, Nurnber ...
... Refining the phenotype Many psychiatric disorders are heterogeneous. Mapping genes in more homogeneous subgroups has been already effective in other complex traits where such groups were defined by age of onset, biological markers, or clinical characteristics.43–50 In a comprehensive review, Nurnber ...
Men’s Health Issues
... morbidity between men and women, but the factor thought to have the most significant impact on the health of men relates to male gender identity, including a tendency for risky behavior [2; 3; 4; 5]. The concept of men’s health was established to focus on the high rates of morbidity and mortality. T ...
... morbidity between men and women, but the factor thought to have the most significant impact on the health of men relates to male gender identity, including a tendency for risky behavior [2; 3; 4; 5]. The concept of men’s health was established to focus on the high rates of morbidity and mortality. T ...
Chapter Chapter 1 / Emergency Management: Evaluation Of The
... tongue and the root of the neck. Lastly, thyroid tissue may migrate beyond the level of the thyroid cartilage into the substernal region, where occasionally a substernal goiter develops. Persistence of the thyroglossal duct results in a thyroglossal cyst or fistula. Thyroglossal cysts are most commo ...
... tongue and the root of the neck. Lastly, thyroid tissue may migrate beyond the level of the thyroid cartilage into the substernal region, where occasionally a substernal goiter develops. Persistence of the thyroglossal duct results in a thyroglossal cyst or fistula. Thyroglossal cysts are most commo ...
8 and Systemic Disease
... A variety of malignancies have been reported in dermatomyositis including colorectal and gastric adenocarcinomas.41 Many or most of the malignancies in this disease are found at presentation or shortly thereafter. In these cases, it is likely that dermatomyositis is of paraneoplastic etiology.48 The ...
... A variety of malignancies have been reported in dermatomyositis including colorectal and gastric adenocarcinomas.41 Many or most of the malignancies in this disease are found at presentation or shortly thereafter. In these cases, it is likely that dermatomyositis is of paraneoplastic etiology.48 The ...
The Risks of Not Breastfeeding for Mothers and Infants M R
... breastfeeding support group. Kramer’s results suggest that hospital policies that support breastfeeding can impact neurodevelopment at school age. These studies were conducted prior to use of formula supplemented with long-chain polyunsaturated fatty acids (LCPUFA), which had been added to infant fo ...
... breastfeeding support group. Kramer’s results suggest that hospital policies that support breastfeeding can impact neurodevelopment at school age. These studies were conducted prior to use of formula supplemented with long-chain polyunsaturated fatty acids (LCPUFA), which had been added to infant fo ...
Recurrent Pregnancy Loss and Its Relation to Combined Parental
... RPL is classically defined as the occurrence of three or more consecutive losses of clinically recognized pregnancies prior to the 20th week of gestation (ectopic and molar pregnancies are not included). The ASRM defines RPL as two or more failed pregnancies (by ultrasound or histopathological exami ...
... RPL is classically defined as the occurrence of three or more consecutive losses of clinically recognized pregnancies prior to the 20th week of gestation (ectopic and molar pregnancies are not included). The ASRM defines RPL as two or more failed pregnancies (by ultrasound or histopathological exami ...
View our poster (1.1 MB PDF)
... Figure 10. Dose-titration of ALN-ANG in female ob/ob mice. Mice received a single SC dose of PBS or ALN-ANG at 0.3, 1, 3, or 9 mg/kg on Day 0. Serum ANGPTL3 levels relative to each animal’s pre-dose baseline were calculated and group averages ± SD are shown. N=4/group. (A) Day 13 serum ANGPTL3 level ...
... Figure 10. Dose-titration of ALN-ANG in female ob/ob mice. Mice received a single SC dose of PBS or ALN-ANG at 0.3, 1, 3, or 9 mg/kg on Day 0. Serum ANGPTL3 levels relative to each animal’s pre-dose baseline were calculated and group averages ± SD are shown. N=4/group. (A) Day 13 serum ANGPTL3 level ...
Genetics of hybrid incompatibility between Lycopersicon esculentum
... identification of the molecular genetic basis of individual loci that contribute to hybrid breakdown (Ting et al. 1998, Barbash et al. 2003, Presgraves et al. 2003). In combination with theoretical work (e.g. Turelli and Orr 1995, 2000), these studies have elegantly demonstrated that, for Drosophila ...
... identification of the molecular genetic basis of individual loci that contribute to hybrid breakdown (Ting et al. 1998, Barbash et al. 2003, Presgraves et al. 2003). In combination with theoretical work (e.g. Turelli and Orr 1995, 2000), these studies have elegantly demonstrated that, for Drosophila ...
Atypical Arteritis in Internal Carotid Arteries: A Novel Concept of
... ICAs. Based on these findings, we suspected TAK or GCA, both of which are types of large-vessel vasculitis or Behçet’s disease, which induces lesions in large– small arteries. We also considered tuberculosis because a tuberculosis patient reportedly developed infectious vasculitis with a primary les ...
... ICAs. Based on these findings, we suspected TAK or GCA, both of which are types of large-vessel vasculitis or Behçet’s disease, which induces lesions in large– small arteries. We also considered tuberculosis because a tuberculosis patient reportedly developed infectious vasculitis with a primary les ...
Complex Heterozygosity Screening with Actin Alanine Scan Alleles
... interactions with 32 actin alanine scan alleles, which target clusters of residues on the surface of actin. A total of 891 deleterious digenic combinations were identified with 203 of the 238 genes. Two-dimensional hierarchical cluster analysis of the interactions identified nine distinct groups, and ...
... interactions with 32 actin alanine scan alleles, which target clusters of residues on the surface of actin. A total of 891 deleterious digenic combinations were identified with 203 of the 238 genes. Two-dimensional hierarchical cluster analysis of the interactions identified nine distinct groups, and ...
The Liverpool Lung Project: a molecular epidemiological study
... dramatic increase in the number of publications in the field of genotype studies and deoxyribonucleic acid (DNA) repair [12, 13] associations with lung cancer. The future lies in combining the data from such analyses [14], in order to develop robust risk assessment models that can contribute to futu ...
... dramatic increase in the number of publications in the field of genotype studies and deoxyribonucleic acid (DNA) repair [12, 13] associations with lung cancer. The future lies in combining the data from such analyses [14], in order to develop robust risk assessment models that can contribute to futu ...
Overview of comments received on `Guideline on - EMA
... draft guideline emphasize the importance of the need to cover different ethnicities and different age groups. However, we also have some concerns regarding the guidelines as they are written at the moment. Firstly, the document is very much written as a summary of successes in pharmacogenetics/genom ...
... draft guideline emphasize the importance of the need to cover different ethnicities and different age groups. However, we also have some concerns regarding the guidelines as they are written at the moment. Firstly, the document is very much written as a summary of successes in pharmacogenetics/genom ...
Pleiotropic effects of methoprene-tolerant (Met), a gene involved in
... variation for the onset of reproduction and for age-specific fecundity. Alleles influenced phenotypic covariances among traits (developmental time and onset of reproduction; onset of reproduction and both early and late fecundity; early and late fecundity), suggesting that alleles of Met vary in their ...
... variation for the onset of reproduction and for age-specific fecundity. Alleles influenced phenotypic covariances among traits (developmental time and onset of reproduction; onset of reproduction and both early and late fecundity; early and late fecundity), suggesting that alleles of Met vary in their ...
The disease characteristics of different strains of scrapie in Sinc
... colony o n the basis of scrapie i n c u b a t i o n period resulted in the p r o d u c t i o n of the V M mouse strain, w h i c h is homozygous for the p7 allele of Sinc. A l m o s t all other laboratory mouse strains tested have b e e n s h o w n to carry the s7 allele of Sinc ( D i c k i n s o n & ...
... colony o n the basis of scrapie i n c u b a t i o n period resulted in the p r o d u c t i o n of the V M mouse strain, w h i c h is homozygous for the p7 allele of Sinc. A l m o s t all other laboratory mouse strains tested have b e e n s h o w n to carry the s7 allele of Sinc ( D i c k i n s o n & ...
Management of Sickle Cell Disease: A Review for Physician
... homozygous disease is associated with a worse disease while the presence of alpha thalassemia (one or two gene deletions) ameliorates the disease. Another variable is the presence of other interacting nonsickle haemoglobin. Of note is fetal haemoglobin (Hb F). Higher proportion of Hb F is associated ...
... homozygous disease is associated with a worse disease while the presence of alpha thalassemia (one or two gene deletions) ameliorates the disease. Another variable is the presence of other interacting nonsickle haemoglobin. Of note is fetal haemoglobin (Hb F). Higher proportion of Hb F is associated ...
Complete comparative genomic analysis of two field isolates of
... dispersed throughout the genome, specific regions have a significantly higher density of changes (Fig. 2). The most variable region is located between hr1 and orf31 (bro-c) (v90/4, 15?0–27?1 kb; v90/2, 15?0–28?3 kb). In this 12?1 kb region (7?7 % of the genome), there are 261 of the 521 point mutati ...
... dispersed throughout the genome, specific regions have a significantly higher density of changes (Fig. 2). The most variable region is located between hr1 and orf31 (bro-c) (v90/4, 15?0–27?1 kb; v90/2, 15?0–28?3 kb). In this 12?1 kb region (7?7 % of the genome), there are 261 of the 521 point mutati ...
anthrax - sfcdcp
... Blood cultures should be obtained prior to antibiotic administration if possible, as they are positive nearly 100% of the time in inhalational anthrax but there is rapid sterilization of blood after a single dose of antibiotics. Other diagnostic tests are under investigation or are available only at ...
... Blood cultures should be obtained prior to antibiotic administration if possible, as they are positive nearly 100% of the time in inhalational anthrax but there is rapid sterilization of blood after a single dose of antibiotics. Other diagnostic tests are under investigation or are available only at ...
WHO/CDS/CSR/EDC/99.1 Influenza Pandemic Plan. The Role of WHO and Guidelines
... Pandemic Planning Committees (NPPCs), responsible for developing strategies appropriate for their countries in advance of the next pandemic. In recognition of the individuality of countries, as well as the unpredictability of influenza, this document emphasizes the processes and issues appropriate f ...
... Pandemic Planning Committees (NPPCs), responsible for developing strategies appropriate for their countries in advance of the next pandemic. In recognition of the individuality of countries, as well as the unpredictability of influenza, this document emphasizes the processes and issues appropriate f ...
Improving Diagnosis and Outcomes of Sjögren`s Disease Through
... among other things, the lack of clear diagnostic test or a pathognomonic sign. Recently, however, serum markers have been isolated that promise to make diagnosis much more straightforward. Aimed at clinicians, this work presents an algorithm to guide diagnosis from dry eye presentation through to fi ...
... among other things, the lack of clear diagnostic test or a pathognomonic sign. Recently, however, serum markers have been isolated that promise to make diagnosis much more straightforward. Aimed at clinicians, this work presents an algorithm to guide diagnosis from dry eye presentation through to fi ...
