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News Letter - Thalassemics India
News Letter - Thalassemics India

... iron concentration. Several studies over the past decade have shown that cardiac T2* is able to predict which patients have a higher risk of presenting symptoms and arrhythmias with an increased risk of cardiac death. Moreover, the exam also proved effective in monitoring chelation therapy, indicati ...
Genetic determination of yield related attributes in Brassica napus
Genetic determination of yield related attributes in Brassica napus

... tendency of oilseeds crops by using genetically manipulated cultivars through intensive and extensive agriculture. Considering the edible oil problems and ...
Greedy Algorithms - University of Illinois at Urbana
Greedy Algorithms - University of Illinois at Urbana

... not exactly the same as in human • However, there are subsets of genes with preserved order between human-mouse (“in synteny”) ...
Traversing the conceptual divide between biological and
Traversing the conceptual divide between biological and

... important for understanding the genetic basis of many common diseases and we argue that it will be possible in the future. This is the promise of what has been called systems biology, the simultaneous study of all the biological pieces together in the context of ecology and evolution to reveal etiol ...
Approach to common endocrine disorders
Approach to common endocrine disorders

... • Agenesis (No goiter) or dysgenesis (aplasia, hypoplasia, ectopic gland) are the commonest causes…..85% • Dyshormonogenesis (10%) and a goiter will be present. Pendred syndrome with sensorineural deafness is the commonest (often euthyroid). • Transplacental maternal TSH receptor blocking Abs (TRBAb ...
Correlated selection responses in animal domestication: chickens
Correlated selection responses in animal domestication: chickens

What is genetics?
What is genetics?

Interactions between SNP Alleles at Multiple Loci Contribute to Skin
Interactions between SNP Alleles at Multiple Loci Contribute to Skin

... regard to skin color. In spite of recent advances in gene identification and functional analysis, much work remains to elucidate the underlying genetic mechanisms regulating normal human skin pigmentation [6]. Our previous study was undertaken to discover the genetic basis of the substantial differe ...
Are you an Effective Communicator
Are you an Effective Communicator

... knee or back, and then change the subject. Another communication challenge for a caregiver is the inability to understand what the individual is expressing. This is a particularly difficult circumstance because it can lead to frustration for the individual. The following are suggestions to help the ...
GAO
GAO

... surveillance systems, which monitor the frequency and distribution of health-related symptoms among people within a specific geographic area. Although syndromic surveillance systems are used by federal agencies and departments and in all of the states whose officials GAO interviewed, concerns have b ...
Rye SCAR markers for male fertility restoration in the P cytoplasm
Rye SCAR markers for male fertility restoration in the P cytoplasm

... The combined linkage map comprising F2 and BC1 segregation data (Figure 1) contains 3 SCAR markers located in the interval between RAPD markers pr23/500 bp and pr743/750 bp, flanking the Rfc1 gene according to a previous study (Stoja³owski et al. 2004b). A strong linkage of the SCAR markers with the ...
Topic guide 7.5: Patterns of inheritance
Topic guide 7.5: Patterns of inheritance

... Mendelian rules but scientists have found that many inheritance patterns follow variations of these rules. Molecular genetics studies are now revealing many subtle interactions between genes and between genes and environment that can affect predicted Mendelian ratios. ...
2010 Newsletter
2010 Newsletter

... scars on their spinal cord. Some of them experience a lot of fluctuations in how they can move around from one day to the next, and often within the same day, thereby greatly limiting activities. Over the past 20 years, it was found that a chemical compound called 4-aminopyridine (aka as fampridine) ...
Frankly Speaking About Cancer: BRCA1/BRCA2 Mutations
Frankly Speaking About Cancer: BRCA1/BRCA2 Mutations

... Trying to understand the science behind cancer and genetics and thinking in terms of your future risk can be daunting. A genetic counselor – someone with specific training in how certain cancers run in families – can help. Genetic counselors ask detailed questions about who in your family (on both y ...
Oviduct-specific Glycoprotein 1 Locus is Associated with Litter Size
Oviduct-specific Glycoprotein 1 Locus is Associated with Litter Size

... introns do not directly alter any amino acid residue, they may play a role in regulating gene expression and thus their constituent SNPs may be directly related to functional variation (Zhang et al., 2005). Furthermore, it should be taken into consideration that the location of OVGP1 gene on chromos ...
Eukaryotic Chromosome Mapping
Eukaryotic Chromosome Mapping

... •Determine which classes are parentals The two parental classes will represent the largest number of offspring in the F2 generation. Information on the parents may be given in the problem description itself. Parentals: red, tall, ragged green, dwarf, normal ...
AMPK_PhD
AMPK_PhD

... MELAS – mitochondrial encephalopathy, lactic acidosis and stroke-like episodes; MILS – maternally inherited Leigh syndrome; LHON – Leber's hereditary optic neuropathy (Leber's disease); NARP – neurogenic weakness ataxia and retinitis pigmentosa. Complex II are rarely affected (Rossignol et al. ...
Paradigms - Trauma Conference
Paradigms - Trauma Conference

... environmental influences’ (Belsky & Pluess, 2009) ...
- Wiley Online Library
- Wiley Online Library

... The developmental delay experienced by our patient, may be explained by the unbalanced chromosomal translocation between chromosomal bands 3p26.3-p26.2 and 10p15.5-p15.1. This is because patients with either of these lesions have been found to have intellectual disability. The causes of the perivent ...
Genetics and genomics for nurses working in general practice
Genetics and genomics for nurses working in general practice

... Hopkinson, I. Presentation at Reality not hype: the new genetics in primary care, 2004. © 2012 NHS National Genetics Education and Development Centre © 2014 NHS National Genetics and Genomics Education Centre ...
PATH 417 Case 3: From India to Canada
PATH 417 Case 3: From India to Canada

2009 - School of Medicine - Case Western Reserve University
2009 - School of Medicine - Case Western Reserve University

... Infection with the human immunodeficiency virus-1 (HIV-1) predisposes patients to Kaposi’s sarcoma (KS), a vascular tumor caused by the Kaposi’s sarcoma–associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV-8). Independent KSHV infection confers far less risk of developing KS versus ...
The genetic epidemiology of idiopathic scoliosis
The genetic epidemiology of idiopathic scoliosis

... [10]. The healthcare costs of bracing, hospitalization, surgery, and chronic back pain are substantial. An understanding of the genetics underlying the disorder would help lead to earlier diagnosis, identification of at-risk individuals, and more effective preventive and/or therapeutic choices. Gene ...
Navigating the HapMap - Oxford Academic
Navigating the HapMap - Oxford Academic

... in the course of the HapMap project have identified and characterized the relationships between four million single nucleotide polymorphisms (SNPs) in four human population samples [1*]. This comprehensive sampling of genetic variation may form the basis of many of the phenotypic differences seen in ...
Use of QTL analysis in physiological research
Use of QTL analysis in physiological research

... of which were found in several, but not all, organs studied. For instance, at the lower end of chromosome 1 QTL for Susy activities were found in hypocotyl, root neck, and lower parts of the roots (root 3), but not in the upper regions of the roots (root 1 and root 2). Other QTL were confined to one ...
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Public health genomics

Public Health Genomics is the use of genomics information to benefit public health. This is visualized as more effective personalized preventive care and disease treatments with better specificity, targeted to the genetic makeup of each patient. According to the CDC, Public Health genomics is an emerging field of study that assesses the impact of genes and their interaction with behavior, diet and the environment on the population’s health.This field of public health genomics is less than a decade old. A number of think tanks, universities, and governments (including the U.S., UK, and Australia) have started public health genomics projects. Research on the human genome is generating new knowledge that is changing public health programs and policies. Advances in genomic sciences are increasingly being used to improve health, prevent disease, educate and train the public health workforce, other healthcare providers, and citizens.
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