Article Relaxed Observance of Traditional Marriage
... marriage rules impose social and economic forces that help structure societies and forge connections between them. However, in those early anthropological studies, the biological benefits or disadvantages of marriage rules could not be determined. We revisit this question by applying a novel simulat ...
... marriage rules impose social and economic forces that help structure societies and forge connections between them. However, in those early anthropological studies, the biological benefits or disadvantages of marriage rules could not be determined. We revisit this question by applying a novel simulat ...
Tuberculosis Surveillance and Screening in Selected High-Risk
... Screening refers to a process that attempts to discover conditions suitable for early preventive or curative intervention. These conditions may not be sufficiently symptomatic to induce patients to seek medical help on their own. Screening may be justified by the prevalence and/or potential severity ...
... Screening refers to a process that attempts to discover conditions suitable for early preventive or curative intervention. These conditions may not be sufficiently symptomatic to induce patients to seek medical help on their own. Screening may be justified by the prevalence and/or potential severity ...
CTLA4 gene polymorphisms are associated with chronic bronchitis
... Therefore, CTLA4 is a candidate gene for COPD and/or chronic bronchitis because of its critical effect on inhibiting the activation of T-cells. As CTLA4 is located near the region on chromosome 2q that showed significant linkage with COPD-related phenotypes both in the Boston Early-Onset COPD Study ...
... Therefore, CTLA4 is a candidate gene for COPD and/or chronic bronchitis because of its critical effect on inhibiting the activation of T-cells. As CTLA4 is located near the region on chromosome 2q that showed significant linkage with COPD-related phenotypes both in the Boston Early-Onset COPD Study ...
Supraclavicular Hydatid Cyst: An Unusual Cause of Neck Swelling
... Cystectomy (surgical excision) is the single effective treatment in hydatid cyst treatment and sufficient by itself. The prognosis is excellent in hydatid cyst cases who are treated by removal of cyst totally without rupture.9 Total excision of the cystic mass was performed surgically in our patient ...
... Cystectomy (surgical excision) is the single effective treatment in hydatid cyst treatment and sufficient by itself. The prognosis is excellent in hydatid cyst cases who are treated by removal of cyst totally without rupture.9 Total excision of the cystic mass was performed surgically in our patient ...
Biliary Tract Disease
... • Extending into adjacent organs (liver, colon) or • Involving vascular structures (Portal vein, hepatic A.) ...
... • Extending into adjacent organs (liver, colon) or • Involving vascular structures (Portal vein, hepatic A.) ...
Genetic Algorithms
... Selection mechanism sensitive for converging populations with close fitness values Generational population model (step 5 in SGA repr. cycle) can be improved with explicit survivor selection ...
... Selection mechanism sensitive for converging populations with close fitness values Generational population model (step 5 in SGA repr. cycle) can be improved with explicit survivor selection ...
Crohn`s disease Evidence Update September 2014
... discussed, and most eventually received treatment with infliximab. Parents reported that the choice to use TNF inhibitors was the most difficult Crohn’s disease-related decision. The severity of disease and quality of life of their children were weighed against the risk of lymphoma and lack of long- ...
... discussed, and most eventually received treatment with infliximab. Parents reported that the choice to use TNF inhibitors was the most difficult Crohn’s disease-related decision. The severity of disease and quality of life of their children were weighed against the risk of lymphoma and lack of long- ...
GENETIC CALCULATOR (BUDGERIGAR) Help File
... other visual variations of Crest (eg, multiple crests, “Helicopters”, Quarter Circles etc). Of those birds displaying crests the accurate genetic prediction of the type of crest is not possible, perhaps due to the influence of modifying genes. Thus, the complete picture is probably of polygenic inhe ...
... other visual variations of Crest (eg, multiple crests, “Helicopters”, Quarter Circles etc). Of those birds displaying crests the accurate genetic prediction of the type of crest is not possible, perhaps due to the influence of modifying genes. Thus, the complete picture is probably of polygenic inhe ...
Hypotonic Infants (From: Pediatric Decision
... myotonic dystrophy; ophthalmoplegia presents but few. Case analysis (1995, Joseph et al.) reported large head circumference in 70%, narrow elongated face in 80%, and slender long digits in 60 % of cases Not associated with cardiomyopathy or CNS or other systems. ...
... myotonic dystrophy; ophthalmoplegia presents but few. Case analysis (1995, Joseph et al.) reported large head circumference in 70%, narrow elongated face in 80%, and slender long digits in 60 % of cases Not associated with cardiomyopathy or CNS or other systems. ...
Essential medicines for rare diseases?
... Conclusion (1): National lists in developing countries Disease common (neglected disease): Treatment cost-effective (e.g. <$300/DALY): medicine listed If most cost-effective treatment is costly: medicine listed; but reduce the price, ration its use and rely on special funds Disease rare: Treat ...
... Conclusion (1): National lists in developing countries Disease common (neglected disease): Treatment cost-effective (e.g. <$300/DALY): medicine listed If most cost-effective treatment is costly: medicine listed; but reduce the price, ration its use and rely on special funds Disease rare: Treat ...
Can there be essential medicines for rare diseases?
... Conclusion (1): National lists in developing countries Disease common (neglected disease): ■ Treatment cost-effective (e.g. <$300/DALY): medicine listed ■ If most cost-effective treatment is costly: medicine listed; but reduce the price, ration its use and rely on special funds Disease rare: ■ Tr ...
... Conclusion (1): National lists in developing countries Disease common (neglected disease): ■ Treatment cost-effective (e.g. <$300/DALY): medicine listed ■ If most cost-effective treatment is costly: medicine listed; but reduce the price, ration its use and rely on special funds Disease rare: ■ Tr ...
Cystic fibrosis – a multiorgan protein misfolding disease
... throughout their lives to address the symptoms of their condition. CF affects many different organ systems, but the most serious consequence of the disease is degeneration of lung function due to chronic respiratory infection and colonization of the airways with opportunistic microbial pathogens. Im ...
... throughout their lives to address the symptoms of their condition. CF affects many different organ systems, but the most serious consequence of the disease is degeneration of lung function due to chronic respiratory infection and colonization of the airways with opportunistic microbial pathogens. Im ...
Recommendations for the development of rare disease drugs using
... in relation to these, ultimately proved useful in facilitating the approval of sapropterin. However, if there is no regulatory precedent for use of the relevant specific biomarker, and if there is no substantial prior clinical data to support the predictive value of the biomarker as a surrogate, the ...
... in relation to these, ultimately proved useful in facilitating the approval of sapropterin. However, if there is no regulatory precedent for use of the relevant specific biomarker, and if there is no substantial prior clinical data to support the predictive value of the biomarker as a surrogate, the ...
Treatment of Pain in Dercum`s Disease with Lidoderm® (Lidocaine 5
... efficacious in alternate forms. Although the existing data suggest a systemic lidocaine effect, low plasma levels of lidocaine administered by transdermal delivery systems likely necessitate that they be utilized directly at the lesion site. The use of this medication might prove to be useful in a tr ...
... efficacious in alternate forms. Although the existing data suggest a systemic lidocaine effect, low plasma levels of lidocaine administered by transdermal delivery systems likely necessitate that they be utilized directly at the lesion site. The use of this medication might prove to be useful in a tr ...
Fever - timg.co.il
... disease include: Male gender Tobacco smoking Diabetes Hematologic malignancy Cancer End-stage renal disease HIV infection. ...
... disease include: Male gender Tobacco smoking Diabetes Hematologic malignancy Cancer End-stage renal disease HIV infection. ...
White Paper: DMET™ Plus allele translation
... candidates in preclinical and development stages is a major problem in drug design: approximately 30 percent of candidates fail.4 This attrition is primarily due to poor pharmacokinetics and toxicity, two risks that can be strongly influenced by genetically determined variation. Thus, pharmaceutical ...
... candidates in preclinical and development stages is a major problem in drug design: approximately 30 percent of candidates fail.4 This attrition is primarily due to poor pharmacokinetics and toxicity, two risks that can be strongly influenced by genetically determined variation. Thus, pharmaceutical ...
QTL Mapping and Analysis for the Traits Related to Pod Dehiscence
... 1.1 Correlation analysis among the three related traits We surveyed the phenotypic evaluations of PD, days of full maturity (DFM), ratio of thickness to width (RTW) in 112 strains of soybean JINF population, and we analyzed the correlation analysis of these three related traits with SPSS 16.0. The r ...
... 1.1 Correlation analysis among the three related traits We surveyed the phenotypic evaluations of PD, days of full maturity (DFM), ratio of thickness to width (RTW) in 112 strains of soybean JINF population, and we analyzed the correlation analysis of these three related traits with SPSS 16.0. The r ...
Table S3 - BioMed Central
... Search by scoring numbers which refer to the relations’ reliability. The score is ‘arbitrary’ and may be between 0 and 10 (the higher the score the more reliable the relation). This score is assigned to the primary databases by the Drug2Gene Team and shall represent the level of curation (e.g. low d ...
... Search by scoring numbers which refer to the relations’ reliability. The score is ‘arbitrary’ and may be between 0 and 10 (the higher the score the more reliable the relation). This score is assigned to the primary databases by the Drug2Gene Team and shall represent the level of curation (e.g. low d ...
Elaboration of EULAR Sjögren`s syndrome Disease - HAL
... outcome measures mainly based on glandular features or patient symptoms, but not systemic features.[2-6] Valid activity indexes are needed [7-9] to assess the effectiveness of new targeted therapies, such as B-cell targeted therapies that have shown promising results for both severe systemic [10, 11 ...
... outcome measures mainly based on glandular features or patient symptoms, but not systemic features.[2-6] Valid activity indexes are needed [7-9] to assess the effectiveness of new targeted therapies, such as B-cell targeted therapies that have shown promising results for both severe systemic [10, 11 ...
Recent retrotransposition events have not affected
... New TEs are correlated with, but not causal to, an increase in expression divergence between human and chimpanzee. (However, TEs may still contribute substantially to within-species variation). We do not find evidence for a TE-induced increase in transcript diversity. Excess of upstream insertions c ...
... New TEs are correlated with, but not causal to, an increase in expression divergence between human and chimpanzee. (However, TEs may still contribute substantially to within-species variation). We do not find evidence for a TE-induced increase in transcript diversity. Excess of upstream insertions c ...
Linkage Mapping of the ACE I Gene in Pig Vincent Nguyen
... genes have been isolated in model organisms and humans that are associated with lifespan. Our hypothesis is that these same genes or regulatory pathways are also important for sow productive life. Angiotensin I converting enzyme (ACE) has been identified as being key to several diseases known to sho ...
... genes have been isolated in model organisms and humans that are associated with lifespan. Our hypothesis is that these same genes or regulatory pathways are also important for sow productive life. Angiotensin I converting enzyme (ACE) has been identified as being key to several diseases known to sho ...
Schlichting, CD and Smith, H
... Recent research using DNA microarray techniques (Ruan et al., 1998) that enable the expression of thousands of genes to be assayed simultaneously has emphasized the complexity and yet the organization underlying expression changes in plants in response to environmental signals. Some techniques allow ...
... Recent research using DNA microarray techniques (Ruan et al., 1998) that enable the expression of thousands of genes to be assayed simultaneously has emphasized the complexity and yet the organization underlying expression changes in plants in response to environmental signals. Some techniques allow ...