Joshua Krämer Dr. med. Pyruvate Kinase Expression and Activity in
... Pyruvate kinase activity is known to be impaired in many forms of cancer because expression is shifted from the tissue-specific pyruvate kinase isoform to the less active isoform M2. This may be relevant to diabetes because there are some links between diabetes and cancer: The two diseases have some ...
... Pyruvate kinase activity is known to be impaired in many forms of cancer because expression is shifted from the tissue-specific pyruvate kinase isoform to the less active isoform M2. This may be relevant to diabetes because there are some links between diabetes and cancer: The two diseases have some ...
Albinism - OG
... gene from the father and the albinism gene from the mother both have to passed on to the kid. The kid needs to have both albinism genes from each parent to have albinism, not just one. If they only have one albino gene, then the child will be considered a “carrier” of an albinism gene. Albinis ...
... gene from the father and the albinism gene from the mother both have to passed on to the kid. The kid needs to have both albinism genes from each parent to have albinism, not just one. If they only have one albino gene, then the child will be considered a “carrier” of an albinism gene. Albinis ...
Kap 13 Quantitative Genetics
... It is commonly observed that tall parents tend to have tall children and vice versa. Actually, the expectation is that the offspring performs intermediate between the parents for additive, quantitative traits. So, how many polymorphic loci are behind a quantitative trait? The answer is usually that ...
... It is commonly observed that tall parents tend to have tall children and vice versa. Actually, the expectation is that the offspring performs intermediate between the parents for additive, quantitative traits. So, how many polymorphic loci are behind a quantitative trait? The answer is usually that ...
Cancer, Genes, Inheritance Pattern, Germ Cell Mutation
... • A carrier of a faulty ‘cancer protection’ gene may never develop cancer unless other cancer protection genes in the cell become faulty over that individual’s lifetime. If cancer does develop however, it may tend to do so earlier in their life. For the same reason, new cancers can develop in more ...
... • A carrier of a faulty ‘cancer protection’ gene may never develop cancer unless other cancer protection genes in the cell become faulty over that individual’s lifetime. If cancer does develop however, it may tend to do so earlier in their life. For the same reason, new cancers can develop in more ...
GENETIC CHARACTERIZATION OF NITRA RABBITS AND ZOBOR
... In an attempt to characterize the two rabbit breeds concerning the shift on the genetic level we studied microsatellite and genetic markers associated with coat color. These two local rabbit breeds, Nitra rabbit (Ni) and Zobor rabbit (Zo) with different phenotypes have a common origin. Based on the ...
... In an attempt to characterize the two rabbit breeds concerning the shift on the genetic level we studied microsatellite and genetic markers associated with coat color. These two local rabbit breeds, Nitra rabbit (Ni) and Zobor rabbit (Zo) with different phenotypes have a common origin. Based on the ...
v5_02_alcoholism_and_our_genes
... • Gene variants that influence the risk of alcoholism also affect behavior in children: • GABRA2 risk-associated variants increase the incidence of conduct disorders. • CHRM2 risk-associated variants increase the incidence of depression. • These findings show there are different pathways and physiol ...
... • Gene variants that influence the risk of alcoholism also affect behavior in children: • GABRA2 risk-associated variants increase the incidence of conduct disorders. • CHRM2 risk-associated variants increase the incidence of depression. • These findings show there are different pathways and physiol ...
Lecture in diabetes mellitus
... The prevalence of diabetes in Western life-style countries is estimated to be between 6,0 and 7,6 %. In some developing countries the prevalence is more than 6 % (Middle East, Western Pacific). The mean percentage prevalence varies between ethnic groups (American Indians,Hispanics, and others). Betw ...
... The prevalence of diabetes in Western life-style countries is estimated to be between 6,0 and 7,6 %. In some developing countries the prevalence is more than 6 % (Middle East, Western Pacific). The mean percentage prevalence varies between ethnic groups (American Indians,Hispanics, and others). Betw ...
Genetics Tutorial
... only physical. But now that you know the risk, you must weigh the consequences before making your decisions to start a family of your own, adopt, or have no children at all. I wish you the best of luck.” One more family to help ...
... only physical. But now that you know the risk, you must weigh the consequences before making your decisions to start a family of your own, adopt, or have no children at all. I wish you the best of luck.” One more family to help ...
Genetic mapping of aphicarus – a sex-linked locus
... represent well-studied examples of alternative phenotypes (Harrison, 1980; Roff, 1986; Zera and Denno, 1997). Insects across a wide range of taxa have evolved the capacity to develop flight-capable (fully winged) phenotypes or flight-incapable (wingless or short-winged) phenotypes. The winged phenot ...
... represent well-studied examples of alternative phenotypes (Harrison, 1980; Roff, 1986; Zera and Denno, 1997). Insects across a wide range of taxa have evolved the capacity to develop flight-capable (fully winged) phenotypes or flight-incapable (wingless or short-winged) phenotypes. The winged phenot ...
Lecture 5: Allelic Effects and Genetic Variances
... • The concept of the average effect of an allele when crossed within its population is easily extended to the average effect of an allele when crossed to a testor. – Called the testcross average effect. • The average effect of allele X in this testcross, !xT , is defined as difference between the me ...
... • The concept of the average effect of an allele when crossed within its population is easily extended to the average effect of an allele when crossed to a testor. – Called the testcross average effect. • The average effect of allele X in this testcross, !xT , is defined as difference between the me ...
Compatible genetic and ecological estimates of dispersal rates in
... Since the dispersal capabilities of most species are substantially less than their geographical ranges, it is intuitive that neighbours are genetically more alike than distantly separated individuals. This contrasts with the island model and is taken into account by the isolationby-distance (IBD) mo ...
... Since the dispersal capabilities of most species are substantially less than their geographical ranges, it is intuitive that neighbours are genetically more alike than distantly separated individuals. This contrasts with the island model and is taken into account by the isolationby-distance (IBD) mo ...
Facts About Myopathies - Muscular Dystrophy Foundation Australia
... muscle tone and contraction by causing over- or underexcitation. A fifth myopathy, nemaline myopathy, is caused by mutations that affect filament proteins. When the filament proteins fail to do their jobs, muscles can't contract properly, causing a loss of tone and strength. At least one myopathy (a ...
... muscle tone and contraction by causing over- or underexcitation. A fifth myopathy, nemaline myopathy, is caused by mutations that affect filament proteins. When the filament proteins fail to do their jobs, muscles can't contract properly, causing a loss of tone and strength. At least one myopathy (a ...
Diverticulosis and Diverticulitis What are diverticulosis and diverticulitis?
... Although not proven, the dominant theory is that a low-fiber diet causes diverticular disease. The disease was first noticed in the United States in the early 1900s, around the time processed foods were introduced into the American diet. Consumption of processed foods greatly reduced Americans’ fiber i ...
... Although not proven, the dominant theory is that a low-fiber diet causes diverticular disease. The disease was first noticed in the United States in the early 1900s, around the time processed foods were introduced into the American diet. Consumption of processed foods greatly reduced Americans’ fiber i ...
Exploring Human Traits - University of Hawaii at Hilo
... With the invention of better microscopes in the late nineteenth century, biologists were able to discover the basic facts of cell division and sexual reproduction. With these new discoveries, scientists began to focus genetics research to understanding how hereditary traits are passed on from parent ...
... With the invention of better microscopes in the late nineteenth century, biologists were able to discover the basic facts of cell division and sexual reproduction. With these new discoveries, scientists began to focus genetics research to understanding how hereditary traits are passed on from parent ...
sex reduces genetic variation: a multidisciplinary review
... mixing. However, until Williams (1966), this selection when applied to evolution of sex was essentially group selection. Williams (1975; also see Williams and Mitton 1973) later provided possible (although tenuous) individual-based selective advantages for sex. Since 1975, the paradox of sex has bee ...
... mixing. However, until Williams (1966), this selection when applied to evolution of sex was essentially group selection. Williams (1975; also see Williams and Mitton 1973) later provided possible (although tenuous) individual-based selective advantages for sex. Since 1975, the paradox of sex has bee ...
Stochastic Gene Expression:
... of a unique combination of transcription factors.4 In large areas of homogeneous color, the relevant transcription factors become expressed in all cells, but the initiation of expression is stochastic. Expression begins in a sparse random pattern of cells that gradually fills in until all cells in t ...
... of a unique combination of transcription factors.4 In large areas of homogeneous color, the relevant transcription factors become expressed in all cells, but the initiation of expression is stochastic. Expression begins in a sparse random pattern of cells that gradually fills in until all cells in t ...
Genome Mapping in the Horse
... denaturated and then hybridised to let the probe anneal to the complementary sequence. Unbound probe is then washed off to allow the visualisation of the specific hybridisation signal using appropriate detection methods. The probes used can vary considerably in size, and range from a few bases to se ...
... denaturated and then hybridised to let the probe anneal to the complementary sequence. Unbound probe is then washed off to allow the visualisation of the specific hybridisation signal using appropriate detection methods. The probes used can vary considerably in size, and range from a few bases to se ...
EBOLA FAQ EBOLA BASICS What is Ebola? Ebola is a type of virus
... Any treatments for Ebola are experimental. There are no approved medications or vaccines to treat the disease. However, a person with Ebola can be treated by: ...
... Any treatments for Ebola are experimental. There are no approved medications or vaccines to treat the disease. However, a person with Ebola can be treated by: ...
Chapter 12
... he laid the groundwork for future genetic studies. But we have learned that things are often more complex: • Over time genes accumulate differences and new alleles arise. • There may be more than two alleles for one character. ...
... he laid the groundwork for future genetic studies. But we have learned that things are often more complex: • Over time genes accumulate differences and new alleles arise. • There may be more than two alleles for one character. ...
1 - bioRxiv
... proposed to explain this sex bias, including differences in sex hormones, pregnancy related risk factors, sexspecific environmental factors, fetal microchimerism, sex-chromosome defects and extremely skewed XCI or failure of XCI31. The so-called loss of mosaicism hypothesis for the onset of autoimmu ...
... proposed to explain this sex bias, including differences in sex hormones, pregnancy related risk factors, sexspecific environmental factors, fetal microchimerism, sex-chromosome defects and extremely skewed XCI or failure of XCI31. The so-called loss of mosaicism hypothesis for the onset of autoimmu ...
Table 3: Illustrates the sample demographics for
... Risk of osteoporosis and associated bone loss conditions are elevated in CD patients [4, 5], resulting in an elevated fracture risk when compared to matched controls (hazard ratio 1.30) [6, 7]. Those patients experiencing gastrointestinal symptoms at diagnosis are also predisposed to lower bone mine ...
... Risk of osteoporosis and associated bone loss conditions are elevated in CD patients [4, 5], resulting in an elevated fracture risk when compared to matched controls (hazard ratio 1.30) [6, 7]. Those patients experiencing gastrointestinal symptoms at diagnosis are also predisposed to lower bone mine ...
S - AIDS Clinical Trials Group
... single PI failure, heavily pretreated, etc. Next review the primary and secondary objects of the study. Primarily focus on the primary objectives and ask if this is a reasonable question to answer, is it important, is it very feasible, etc? I think the most important areas to review are the inclusio ...
... single PI failure, heavily pretreated, etc. Next review the primary and secondary objects of the study. Primarily focus on the primary objectives and ask if this is a reasonable question to answer, is it important, is it very feasible, etc? I think the most important areas to review are the inclusio ...
S - AIDS Clinical Trials Group
... single PI failure, heavily pretreated, etc. Next review the primary and secondary objects of the study. Primarily focus on the primary objectives and ask if this is a reasonable question to answer, is it important, is it very feasible, etc? I think the most important areas to review are the inclusio ...
... single PI failure, heavily pretreated, etc. Next review the primary and secondary objects of the study. Primarily focus on the primary objectives and ask if this is a reasonable question to answer, is it important, is it very feasible, etc? I think the most important areas to review are the inclusio ...