SIGNATURES OF NATURAL SELECTION IN THE HUMAN GENOME
... most polymorphisms and fixed differences between species are selectively neutral8,9. This proposition was called the neutral theory of molecular evolution, or the neutral theory. The development of the neutral theory was motivated by two principal observations. First, between-species comparisons of ...
... most polymorphisms and fixed differences between species are selectively neutral8,9. This proposition was called the neutral theory of molecular evolution, or the neutral theory. The development of the neutral theory was motivated by two principal observations. First, between-species comparisons of ...
Gaucher disease National Diagnosis and Treatment Protocol
... administration in a hospital setting during the first 2 years. If the patient has a history of adverse effects suggesting hypersensitivity, an adrenaline kit must be available at home. Imiglucerase should only be administered to pregnant woman when it is formally indicated and after careful assessme ...
... administration in a hospital setting during the first 2 years. If the patient has a history of adverse effects suggesting hypersensitivity, an adrenaline kit must be available at home. Imiglucerase should only be administered to pregnant woman when it is formally indicated and after careful assessme ...
signatures of natural selection in the human
... most polymorphisms and fixed differences between species are selectively neutral8,9. This proposition was called the neutral theory of molecular evolution, or the neutral theory. The development of the neutral theory was motivated by two principal observations. First, between-species comparisons of ...
... most polymorphisms and fixed differences between species are selectively neutral8,9. This proposition was called the neutral theory of molecular evolution, or the neutral theory. The development of the neutral theory was motivated by two principal observations. First, between-species comparisons of ...
sample - Test Bank Corp
... 3) The nurse is caring for a client in the clinic whom she suspects has vaginosis. Which test best determines whether this sexually active woman has the disorder? 1. The observation of mycelia upon direct microscopy in a 10% potassium hydroxide preparation 2. The addition of a 10% potassium hydroxid ...
... 3) The nurse is caring for a client in the clinic whom she suspects has vaginosis. Which test best determines whether this sexually active woman has the disorder? 1. The observation of mycelia upon direct microscopy in a 10% potassium hydroxide preparation 2. The addition of a 10% potassium hydroxid ...
Estimating lethal allele frequencies in complex pedigrees via gene
... The GC method was proposed by ALLAIRE et al. (1982). This approach calculates the expected lethal allele frequency from known individual genotypes (carriers) among a set of relevant ancestors. Here we used a Fortran program written by LIDAUER and ESSL (1994) based on a concept developed by ALLAIRE e ...
... The GC method was proposed by ALLAIRE et al. (1982). This approach calculates the expected lethal allele frequency from known individual genotypes (carriers) among a set of relevant ancestors. Here we used a Fortran program written by LIDAUER and ESSL (1994) based on a concept developed by ALLAIRE e ...
L1 + L2- (GERD) and peptic ulcer
... Morphology • Gross • usually less than 20 mm in diameter but they may > 100 mm in diameter. • The classic peptic ulcer is a round to oval, sharply punched-out defect • In contrast, heaped-up margins are more characteristic of cancers • Microscopy • the base consists of necrotic tissue and polymorph ...
... Morphology • Gross • usually less than 20 mm in diameter but they may > 100 mm in diameter. • The classic peptic ulcer is a round to oval, sharply punched-out defect • In contrast, heaped-up margins are more characteristic of cancers • Microscopy • the base consists of necrotic tissue and polymorph ...
BMC Public Health
... throughout the period of analysis. Current levels of DOTS coverage have been achieved with assistance from foreign donors – hence we implicitly accounted for current foreign assistance. However, we did not explicitly add in these expenditures, since they would have been added to both strategies, mak ...
... throughout the period of analysis. Current levels of DOTS coverage have been achieved with assistance from foreign donors – hence we implicitly accounted for current foreign assistance. However, we did not explicitly add in these expenditures, since they would have been added to both strategies, mak ...
principles and practice of screening for disease
... The aim of early disease detection (sometimes called secondary prevention) is simple. Primary prevention seeks to abolish disease by protecting the individual and the population from attack before the challenge has been made. Early detection (case-finding) aims at discovering and curing conditions w ...
... The aim of early disease detection (sometimes called secondary prevention) is simple. Primary prevention seeks to abolish disease by protecting the individual and the population from attack before the challenge has been made. Early detection (case-finding) aims at discovering and curing conditions w ...
the art and design of genetic screens
... Wieschaus and Trudi Schüpbach, carried out saturation mutageneses for maternal-effect mutations, which identified many of the genes that are involved in generating the four maternal signals that define the two main axes of the embryo14,15 (FIG. 2c). A second class of genes that were missed in the sc ...
... Wieschaus and Trudi Schüpbach, carried out saturation mutageneses for maternal-effect mutations, which identified many of the genes that are involved in generating the four maternal signals that define the two main axes of the embryo14,15 (FIG. 2c). A second class of genes that were missed in the sc ...
Genome-Wide Analysis of Core Cell Cycle Genes in
... and well-defined prediction protocol is used by the different annotation centers, which results in the generation of redundant, nonuniform structural annotations. Furthermore, clear information is lacking on the methods and programs used as well as the motivation for applying special protocols, maki ...
... and well-defined prediction protocol is used by the different annotation centers, which results in the generation of redundant, nonuniform structural annotations. Furthermore, clear information is lacking on the methods and programs used as well as the motivation for applying special protocols, maki ...
Implementing array comparative genomic hybridization in male
... Some work has been done to identify additional candidate genes via animal model approaches, but there have been several limitations to identify novel genes associated with male infertility. These limitations include inappropriate controls, single gene analysis, lack of family pedigrees to corroborat ...
... Some work has been done to identify additional candidate genes via animal model approaches, but there have been several limitations to identify novel genes associated with male infertility. These limitations include inappropriate controls, single gene analysis, lack of family pedigrees to corroborat ...
Nucleic Acids Research, 32: D489-D492 (2004).
... which are less than 15 million years old (2). Because of their newness, some Alu-Y elements have neither reached ®xation nor been lost, and they exist in a polymorphic state. Most Alu repeats in the human genome belong to the Alu-S class, with Alu-Sx being the commonest (2). Despite their being gene ...
... which are less than 15 million years old (2). Because of their newness, some Alu-Y elements have neither reached ®xation nor been lost, and they exist in a polymorphic state. Most Alu repeats in the human genome belong to the Alu-S class, with Alu-Sx being the commonest (2). Despite their being gene ...
Counterpoint: Long-Term Antibiotic Therapy Improves Persistent
... within macrophages provides a possible pathogenetic mechanism for chronic or recurring Lyme disease” [67, p. 909]. In another study, “nine months after treatment, low levels of spirochete DNA could be detected by real time PCR in a subset of antibiotic treated mice” [68, p. 1430]. So at least in the ...
... within macrophages provides a possible pathogenetic mechanism for chronic or recurring Lyme disease” [67, p. 909]. In another study, “nine months after treatment, low levels of spirochete DNA could be detected by real time PCR in a subset of antibiotic treated mice” [68, p. 1430]. So at least in the ...
pathogenesis of salmonellosis in humans
... development in the body, and type of manifestation, whether it is acute, chronic, or recurrent. The word comes from the Greek pathos ("disease") and genesis ("creation"). An infectious process can only begin after living Salmonella (not only their toxins) reach the gastrointestinal tract. Some of th ...
... development in the body, and type of manifestation, whether it is acute, chronic, or recurrent. The word comes from the Greek pathos ("disease") and genesis ("creation"). An infectious process can only begin after living Salmonella (not only their toxins) reach the gastrointestinal tract. Some of th ...
The Gene Ontology
... • Language used in biological research is not well controlled – This is hampered further by the wide variations in terminology that may be common usage at any given time, which inhibit effective searching by both computers and people. Adopted from http://www.geneontology.org/ ...
... • Language used in biological research is not well controlled – This is hampered further by the wide variations in terminology that may be common usage at any given time, which inhibit effective searching by both computers and people. Adopted from http://www.geneontology.org/ ...
A Tuberculosis Guide for Specialist Physicians
... Chapter 9 Treatment of tuberculosis . . . . . . . . . . . . . . . . . . . . . . . 146 A brief history. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 147 Microbiological bases for the treatment of tuberculosis . . . . . . . . . . . . Prevention of resistance: the need for ...
... Chapter 9 Treatment of tuberculosis . . . . . . . . . . . . . . . . . . . . . . . 146 A brief history. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 147 Microbiological bases for the treatment of tuberculosis . . . . . . . . . . . . Prevention of resistance: the need for ...
Microarray Data Analysis
... application is to make meaningful biological inference about the set of genes or samples using class prediction. This is based on supervised data analysis methods that impose known groups on data sets, like the k-nearest neighborhood (kNN) classification method. Finally, it also employs the hierarch ...
... application is to make meaningful biological inference about the set of genes or samples using class prediction. This is based on supervised data analysis methods that impose known groups on data sets, like the k-nearest neighborhood (kNN) classification method. Finally, it also employs the hierarch ...
Gastrointestinal Infection Outbreak Guidelines for Healthcare Facilities
... ability to be rapidly transmitted in healthcare settings among individuals who often are highly susceptible. Episodes of infectious GI infections account for a significant proportion of all patients/residents/clients in healthcare settings who develop diarrhea with or without nausea and/or vomiting. ...
... ability to be rapidly transmitted in healthcare settings among individuals who often are highly susceptible. Episodes of infectious GI infections account for a significant proportion of all patients/residents/clients in healthcare settings who develop diarrhea with or without nausea and/or vomiting. ...
14.10.Acceptable-Abbreviations-Acronyms-for-Charting
... parentheses (), semi-colon ; or quotes “ ”) in Horizon HomeCare EHR. 1. Whenever information is placed within the record and a symbol or abbreviation is utilized, staff must use only those abbreviations and symbols that have been approved as accepted. ...
... parentheses (), semi-colon ; or quotes “ ”) in Horizon HomeCare EHR. 1. Whenever information is placed within the record and a symbol or abbreviation is utilized, staff must use only those abbreviations and symbols that have been approved as accepted. ...
A Study of Gene Linkage and Mapping Using Tetrad Analysis
... collectively called a tetrad. In most organisms the products of each meiotic division are not kept separate but become part of a “pool” of meiotic products (gametes). The mating activities of the parents combine these meiotic products in a random fashion to produce the next generation. Thus, in most ...
... collectively called a tetrad. In most organisms the products of each meiotic division are not kept separate but become part of a “pool” of meiotic products (gametes). The mating activities of the parents combine these meiotic products in a random fashion to produce the next generation. Thus, in most ...
Tutorial: RNA-Seq Analysis Part II (Tracks): Non-Specific
... The term non-specific matches refers to reads that can be mapped equally well to more than one location on your reference. Since it is not possible to tell which transcript such reads actually came from, the Workbench has to decide where to place them. In such cases, the Workbench first estimates th ...
... The term non-specific matches refers to reads that can be mapped equally well to more than one location on your reference. Since it is not possible to tell which transcript such reads actually came from, the Workbench has to decide where to place them. In such cases, the Workbench first estimates th ...
M.Tevfik Dorak, BA (Hons), MD, Ph.D.
... into several metabolites and which are excreted into urine where they cause a mousy smell. Understanding the condition has led to a treatment. Patients must be placed on a diet with very little phenylalanine until they are teenagers. The diet must be started within a few weeks of birth, the earlier ...
... into several metabolites and which are excreted into urine where they cause a mousy smell. Understanding the condition has led to a treatment. Patients must be placed on a diet with very little phenylalanine until they are teenagers. The diet must be started within a few weeks of birth, the earlier ...
Evolution of Phenotypic Robustness
... clarification of three key notions of this definition, namely the character state, the source of variation, and the reference set of alternative states. Genotypic and population states Since phenotypic robustness describes how variation in genotypic or environmental values is translated into variati ...
... clarification of three key notions of this definition, namely the character state, the source of variation, and the reference set of alternative states. Genotypic and population states Since phenotypic robustness describes how variation in genotypic or environmental values is translated into variati ...
MMRF and Inflection collaborate on new cancer
... of Nanopatch-based vaccine products, as well as those with partners,” said David L. Hoey, president and CEO of Vaxxas. “This funding creates an important inflection point for Vaxxas, as we are now poised to create significantly increased value through our first clinical studies.” Vaxxas’ proprietary ...
... of Nanopatch-based vaccine products, as well as those with partners,” said David L. Hoey, president and CEO of Vaxxas. “This funding creates an important inflection point for Vaxxas, as we are now poised to create significantly increased value through our first clinical studies.” Vaxxas’ proprietary ...