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Breast Cancer Avoidance
Breast Cancer Avoidance

... women, losing weight would lower this cancer risk by nearly two-thirds. Further, last year in the largest review of research into lifestyle and breast cancer, the American Institute of Cancer Research estimated that about 40 percent of U.S. breast cancer cases, or about 70,000 cases every year, coul ...
General background text Pharmacogenetics
General background text Pharmacogenetics

... The process of genotyping is used to determine the genotype. It indicates which alleles of the gene for TPMT are present in the tested individual. Each allele has a name that consists of a star (*) and a number, an example of a possible TPMT genotype is TPMT*1/*3A. Many variations exist for TPMT, mo ...
CHANGES IN THE EXPRESSION OF THREE COLD
CHANGES IN THE EXPRESSION OF THREE COLD

... ‘Selvik’. Expression profiles of three genes (CBF4, COR47 and F3H) were determined at three time-points: 0, 6 and 12 weeks after sub-zero treatment at -12 °C. The CBF4 gene was very strongly up-regulated in ‘Selvik’ plants and the highest value of the transcript level was detected just after the tre ...
Lynch Syndrome Genetic Testing for Hereditary Colorectal Cancer
Lynch Syndrome Genetic Testing for Hereditary Colorectal Cancer

... of colorectal cancers are not due to inherited causes. Only about 10% of cancer is “hereditary” (due to inherited genetic causes). People who carry these genetic changes are born with them— they do not develop over time. Understanding if a family history of cancer is due to inherited genetic causes ...
The effects of polymorphisms in DGAT1, GH and GHR genes
The effects of polymorphisms in DGAT1, GH and GHR genes

File
File

Patient Information: Genetic Screening What is genetic screening
Patient Information: Genetic Screening What is genetic screening

... □ Sickle Cell Screening Sickle cell anemia is another severe blood condition, in which the red blood cells tend to become abnormal in shape. When these red cells go through the small blood vessels, they tend to get stuck and block further blood flow, causing pain, damage and a low blood count. It ca ...
At Least Two Thirds of Breast Cancer Cases are Likely Avoidable
At Least Two Thirds of Breast Cancer Cases are Likely Avoidable

... cases, or about 70,000 cases every year, could be prevented by making lifestyle changes. It is my strong belief that these estimates are seriously low, and it is more likely that at least two-thirds - or even greater than 90 percent of breast cancers can be avoided by rigidly applying the recommenda ...
of dog and human
of dog and human

... breeding, dogs have greater genetic uniformity so locating disease-causing genes is easier. Unfortunately, treatment options for these types of complex diseases are limited. That’s where TGen steps in. ...
Exercise - GEP Community Server - Washington University in St. Louis
Exercise - GEP Community Server - Washington University in St. Louis

... Gene Annotation: When we annotate a gene, we will use gene prediction tracks, D. mel Proteins track and other evidence tracks to define the precise location of the coding DNA sequences (CDS) within the genomic sequence. Note that “gene” is not synonymous with transcript or CDS. Gene includes regulat ...
14–16 Video transcript: Chickens and Campylobacter
14–16 Video transcript: Chickens and Campylobacter

... on the DNA sequencer. So when I've set up the sequencing reactions and they've all been cleaned up, then we take them to our sequencing lab upstairs, and they're run through an automated DNA analyser. We get the data back as electropherograms. We then assemble a forward and reverse strand, so that's ...
Help File
Help File

... The father has a genotype of Dd. What is his phenotype? _________________________ (Remember phenotype refers to the traits that show on the outside of a person. Does dad have dimples or no dimples?) ...
Some computing solutions to your data problems
Some computing solutions to your data problems

... all proteins identified, find information on the web which might shed light on their function • Case 2: interpret data on human proteins differentially expressed in human cells invaded by Toxoplasma ...
Textbook Reference: Section 17.3
Textbook Reference: Section 17.3

... Gregor Mendel used the scientific process to lay the foundation for the science of genetics through his study of pea plants. The “factors” described by Mendel were later called genes. Formulated the Law of Dominance, Law of Segregation and Law of Independent Assortment 1902- Walter Sutton and Theodo ...
Great Discoveries in Science: The Double Helix [JUDSON:] In the
Great Discoveries in Science: The Double Helix [JUDSON:] In the

... everything that could prove relevant for their ongoing-- but now underground-- quest to discover the structure of DNA. [WATSON:] To me there was only one way I could be happy... or two ways, you know: solve DNA or get a girlfriend... [laughs] and I didn't get a girlfriend, so it was solve DNA. [JUDS ...
Practice Exam
Practice Exam

... 10. (6) Drosophila eyes are normally red. Several purple-eyed strains have been isolated as spontaneous mutants, and the purple phenotype has been shown to be inherited as a Mendelian autosomal recessive in each case. To investigate allelism between these different purple mutations, a __complementat ...
Carroll 2006 Fossil Genes
Carroll 2006 Fossil Genes

... most other vertebrates have at least one version of this opsin, we know that coelaca~ithancestors also had this gene, so somewhere along the line of coelacanth evolution the MWS/LWS opsin gene was lost. T h e loss of this gene raises a very general question: How and why is a gene that is so useful t ...
A common variant in chromosome 9p21 associated with RESEARCH NOTE
A common variant in chromosome 9p21 associated with RESEARCH NOTE

... the 9p21 region in the etiopathology of CAD in Asian Indians. The odds ratio and the population attributable risk percentage for this CAD associated variant in men remain as the highest reported for rs10757278 to date (Helgadottir et al. 2007; McPherson et al. 2007; Samani et al. 2007; Wellcome Trus ...
AP Biology - TeacherWeb
AP Biology - TeacherWeb

Biogerontology: The Next Step
Biogerontology: The Next Step

... describe genes whose altered activity influences aging and longevity.12,14 Two kinds of gerontogene action are postulated to be responsible for the emergence of the aging phenotype. The first considers the role of late-acting mutations that are already present at the time of fertilization and birth ...
Lesson Overview
Lesson Overview

... Disruptive selection occurs when individuals at the upper and lower ends of the curve have higher fitness than individuals near the middle. For example, in an area where medium-sized seeds are less common, birds with unusually small or large beaks would have higher fitness. Therefore, the population ...
changes in the expression of three cold
changes in the expression of three cold

... ‘Selvik’. Expression profiles of three genes (CBF4, COR47 and F3H) were determined at three time-points: 0, 6 and 12 weeks after sub-zero treatment at -12 °C. The CBF4 gene was very strongly up-regulated in ‘Selvik’ plants and the highest value of the transcript level was detected just after the tre ...
PDF - Journal of Cancer Metastasis and Treatment
PDF - Journal of Cancer Metastasis and Treatment

Metabolic medicine: new developments in diagnosis and treatment
Metabolic medicine: new developments in diagnosis and treatment

... The extensive study of genes involved in inborn errors of metabolism has not only revealed the diseasecausing mutations, but also many "neutral" ones (without apparent effect on phenotype). However, significant numbers of such "benign" mutations and polymorphisms have been subsequently recognized to ...
function Complex genomic rearrangements lead to novel primate gene
function Complex genomic rearrangements lead to novel primate gene

... The most striking of the primate-specific gene families identified in our screen originated from RanBP2, the largest nucleoporin characterized so far (Wu et al. 1995; Yokoyama et al. 1995). The duplicated copies also acquired an additional domain from the recently described trans-Golgi protein GCC2 ...
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Nutriepigenomics

Nutriepigenomics is the study of food nutrients and their effects on human health through epigenetic modifications. There is now considerable evidence that nutritional imbalances during gestation and lactation are linked to non-communicable diseases, such as obesity, cardiovascular disease, diabetes, hypertension, and cancer. If metabolic disturbances occur during critical time windows of development, the resulting epigenetic alterations can lead to permanent changes in tissue and organ structure or function and predispose individuals to disease.
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