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Epidemiologic Triads & Natural History of Disease
Epidemiologic Triads & Natural History of Disease

... •Agent factors include infectious microorganisms, e.g. virus, bacterium, parasite, or other agents. •They may be necessary but not always sufficient alone to ...
Human Herpesvirus-8
Human Herpesvirus-8

...  Pathogenesis of HHV-8 disease is unclear  KS and PEL usually seen in advanced immunosuppression (CD4 count <200 cells/µL), but can occur at any CD4 count  KS incidence up to 30% among AIDS patients in United States before use of effective ART  Dramatically lower incidence in recent years  ART ...
Staggering Disease in a Cat - The Journal of Applied Research in
Staggering Disease in a Cat - The Journal of Applied Research in

... context with published laboratory data was not available.3 Although transmission of BDV is still not definitively described, it could occur via nasal and buccal secretions and orally. The virus infects nerve endings of the olfactory epithelium and migrates intra-axonally to the CNS where it induces ...
Pregnancy and Lyme disease
Pregnancy and Lyme disease

... of 83-100%. Due to the high false positive rates of this test a second confirmatory test is then performed by Western Blot testing to detect antibodies to the organism. Typically, IgM antibodies to B. burgdorferi are present within 2-4 weeks after the tick bite. IgG antibodies appear after 6-8 weeks ...
Ankylosing Spondylitis Genotyping (HLA-B27)
Ankylosing Spondylitis Genotyping (HLA-B27)

... family history – <1% • Analytical sensitivity/specificity – >99% Results • Positive – one copy of HLA-B27 detected o Associated with AS and related disorders (Reiter syndrome, anterior uveitis, psoriatic arthritis, and inflammatory bowel disease) • Negative – no copy of HLA-B27 identified o Does not ...
The Neuropsychiatric Manifestations of Lyme Disease and Other
The Neuropsychiatric Manifestations of Lyme Disease and Other

... increased in pulmonary tuberculosis and other chronic infections. Zinc and copper levels normalize after antitubercular therapy. Zinc and copper given together was found to be more effective in treating Trypanosoma infection than either zinc or copper alone. ...
scrapie - An-Najah Blogs - An
scrapie - An-Najah Blogs - An

... Most breeds of sheep are affected although in some there is a clear genetic basis for resistance or low prevalence of clinical disease, scrapie has also been described in Moufflon (Ovis musimon) a primitive type of sheep such animal incubating the disease and that animal never develop clinical signs ...
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The Transverse Myelitis Association ...advocating for those with
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... are left severely functionally disabled. Most show good to fair recovery. Some studies have shown that the rapid progression of clinical symptoms, the presence of back pain, and the presence of spinal shock, as well as paraclinical evidence, such as absent central conduction on evoked potential test ...
Sexually transmitted diseases (STDs)
Sexually transmitted diseases (STDs)

... Primary syphilis The first sign of syphilis, which may occur from 10 days to three months after exposure, may be a small, painless sore (chancre) on the part of your body where the infection was transmitted, usually your genitals, rectum, tongue or lips. A single chancre is typical, but there may be ...
Mollusca contagiosa
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... acquiring mollusca contagiosa and may therefore have more widespread disease. Mollusca contagiosa in pregnancy During pregnancy the immune system is altered, therefore pregnant women may have a higher risk of acquiring mollusca. There are no risks for the unborn child; however, the disease may sprea ...
4. Folliculitis
4. Folliculitis

... multiple hair follicles. When a furuncle occurs over a long period of time or when multiple furuncles occur at the same time, it is called furunculosis. ● Administration of antibiotics, and incision and drainage of pus are the main treatments. Clinical features A small red follicular papule or pustu ...
header - Foundations of Naturopathic Medicine Project
header - Foundations of Naturopathic Medicine Project

... is a many-faceted being existing on a number of levels or planes of being. . While these traditions may differ in detail they are somewhat similar in that the spiritual body or plane is the highest or most important. followed by the mental or perhaps, psychological level with the physical level bein ...
Bacteria, Fungi, and Viruses-OH MY!!
Bacteria, Fungi, and Viruses-OH MY!!

... –½ cup bleach with 1 gallon of water o 1:10 for ring worm –1.5 cups bleach with 1 gallon of water • Know your contact times • Inappropriate concentrations can be hazardous – more is not better! ...
Rhytidectomy: Evolution and Current Concepts
Rhytidectomy: Evolution and Current Concepts

... • 40 million visits by adults to medical facilities per year • More prescription written for pharyngitis than any other respiratory infection ...
Chapter 29: Additional Health Conditions
Chapter 29: Additional Health Conditions

... Small organism that can live only in a cell Upon entering cell it may immediately trigger a disease (influenza) or remain dormant (herpes) Can damage host cell by blocking normal function and using metabolism for own reproduction Virus ultimately destroys cell ...
lymphoma 2011
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Chapter 6 Disease Chapter 7 Diagnosis and Treatment

... intravenous fluids, oxygen, and certain lifesaving medications. At medical facilities, EMTs work closely with physicians and nurses, reporting on histories, physical examinations, and measures taken to stabilize the patient. Most EMTs receive their training from a college or technical school and mus ...
Unilateral, nontender, vulvar swelling as the presenting sign of
Unilateral, nontender, vulvar swelling as the presenting sign of

... biopsy specimens of the colon revealed granulomatous inflammation, consistent with CD. Treatment was commenced with oral corticosteroid and metronidazole with marked improvement in 2 months’ treatment. During one and half year follow up, several diarrheal episodes occurred but her symptom was genera ...
How to Investigate a Disease Outbreak
How to Investigate a Disease Outbreak

... needed to focus the investigation on a specific problem. The case definition should distinguish the disease under investigation from other conditions that are more common and may be occurring simultaneously at the normal, expected frequency in the population. It is not a good idea to try to investig ...
Aicardi-Goutières syndrome: differential diagnosis and
Aicardi-Goutières syndrome: differential diagnosis and

... Aicardi-Goutières syndrome (AGS) is a progressive encephalopathy with onset in the first year of life and a recessive autosomal pattern of inheritance. The syndrome is characterised by acquired microcephaly, basal ganglia calcifications, white matter abnormalities, chronic cerebrospinal fluid (CSF) ...
Psychiatry Grand Rounds December 13, 2006
Psychiatry Grand Rounds December 13, 2006

... several important neuropsychiatric disorders…several infectious diseases including human influenza virus, HIV, syphilis and Lyme disease are associated with neuropsychiatric symptoms following transmission of infectious agents to the central nervous system. …evidence also points to potential for per ...
Psittacine beak and feather disease (or psittacine circovirus, PCV)
Psittacine beak and feather disease (or psittacine circovirus, PCV)

... and death. These very young birds may die before any feather abnormalities are seen. The acute form affects young birds during their first feather formation when they replace their neonatal down. Acute infections are characterised by several days of depressed behaviour, followed by sudden changes in ...
5141.5R - Communicable Conditions
5141.5R - Communicable Conditions

... confined to persons with a direct need to know. If it becomes necessary to inform others, these persons will be provided with information concerning necessary precautions and will be made aware of ...
Oral ulcers Mutaz Ali Hassan Faculty of Dentistry University of
Oral ulcers Mutaz Ali Hassan Faculty of Dentistry University of

... The term immunemediated sub-epithelial blistering diseases (IMSEBD) has therefore been used. Immunological differences may account for the significant differences in their clinical presentation and responses to therapy, but unfortunately data on this are few. Diagnosis The diagnosis and management o ...
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Multiple sclerosis



Multiple sclerosis (MS), also known as disseminated sclerosis or encephalomyelitis disseminata, is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged. This damage disrupts the ability of parts of the nervous system to communicate, resulting in a wide range of signs and symptoms, including physical, mental, and sometimes psychiatric problems. MS takes several forms, with new symptoms either occurring in isolated attacks (relapsing forms) or building up over time (progressive forms). Between attacks, symptoms may disappear completely; however, permanent neurological problems often occur, especially as the disease advances.While the cause is not clear, the underlying mechanism is thought to be either destruction by the immune system or failure of the myelin-producing cells. Proposed causes for this include genetics and environmental factors such as infections. MS is usually diagnosed based on the presenting signs and symptoms and the results of supporting medical tests.There is no known cure for multiple sclerosis. Treatments attempt to improve function after an attack and prevent new attacks. Medications used to treat MS, while modestly effective, can have adverse effects and be poorly tolerated. Many people pursue alternative treatments, despite a lack of evidence. The long-term outcome is difficult to predict, with good outcomes more often seen in women, those who develop the disease early in life, those with a relapsing course, and those who initially experienced few attacks. Life expectancy is on average 5 to 10 years lower than that of an unaffected population.Multiple sclerosis is the most common autoimmune disorder affecting the central nervous system. As of 2008, between 2 and 2.5 million people are affected globally with rates varying widely in different regions of the world and among different populations. In 2013, 20,000 people died from MS, up from 12,000 in 1990. The disease usually begins between the ages of 20 and 50 and is twice as common in women as in men. The name multiple sclerosis refers to scars (sclerae—better known as plaques or lesions) in particular in the white matter of the brain and spinal cord. MS was first described in 1868 by Jean-Martin Charcot. A number of new treatments and diagnostic methods are under development.
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