chicken.db - Bioconductor
... indicates the chromosome. Due to inconsistencies that may exist at the time the object was built, these vectors may contain more than one chromosome and/or location. If the chromosomal location is unknown, the vector will contain an NA. Chromosomal locations on both the sense and antisense strands a ...
... indicates the chromosome. Due to inconsistencies that may exist at the time the object was built, these vectors may contain more than one chromosome and/or location. If the chromosomal location is unknown, the vector will contain an NA. Chromosomal locations on both the sense and antisense strands a ...
Genetics of Hemophilia
... have their lifetime’s supply of oocytes as embryos. The primary oocyte, with 46 chromosomes, starts to enter meiosis while the female is still an embryo, then remains in a sort of maturation arrest for many years until ovulation. At ovulation, meiosis continues, with more opportunities for crossover ...
... have their lifetime’s supply of oocytes as embryos. The primary oocyte, with 46 chromosomes, starts to enter meiosis while the female is still an embryo, then remains in a sort of maturation arrest for many years until ovulation. At ovulation, meiosis continues, with more opportunities for crossover ...
The Use of Benlate for Distinguishing Between Haploid and Diploid
... Supporting evidence also comes from the parasexual analyses of the five diploid strains. These diploids were all more sensitive to Benlate than their parental haploid strains, and to the meiotic progeny from the three crosses. The parasexual segregants were provisionally classified as diploid or hap ...
... Supporting evidence also comes from the parasexual analyses of the five diploid strains. These diploids were all more sensitive to Benlate than their parental haploid strains, and to the meiotic progeny from the three crosses. The parasexual segregants were provisionally classified as diploid or hap ...
The Use of Benlate for Distinguishing Between Haploid and Diploid
... Supporting evidence also comes from the parasexual analyses of the five diploid strains. These diploids were all more sensitive to Benlate than their parental haploid strains, and to the meiotic progeny from the three crosses. The parasexual segregants were provisionally classified as diploid or hap ...
... Supporting evidence also comes from the parasexual analyses of the five diploid strains. These diploids were all more sensitive to Benlate than their parental haploid strains, and to the meiotic progeny from the three crosses. The parasexual segregants were provisionally classified as diploid or hap ...
Hepatocyte-Cfh -/- mice have reduced plasma FH and C3
... and 4). Glomerular C3 was highest in the hepatocyte-Cfh-/- mice (Figure 3F). Differences in glomerular IgG and sheep IgG were minimal and the immune response to sheep IgG in adjuvant was equivalent between the experimental groups (supplemental Figures 4-6). CfhloxP/loxP mice, in which we had demonst ...
... and 4). Glomerular C3 was highest in the hepatocyte-Cfh-/- mice (Figure 3F). Differences in glomerular IgG and sheep IgG were minimal and the immune response to sheep IgG in adjuvant was equivalent between the experimental groups (supplemental Figures 4-6). CfhloxP/loxP mice, in which we had demonst ...
22q12 and 22q13 duplications
... Babies with a 22q12/13 duplication are often, but not always, small and underweight at birth with an average birth weight of 2.94 kg (6lb 8oz). The range of birth weights is between 1.3 kg (2lb 14oz) and 4.48 kg (9lb 14oz). However, half (5/10) had a low birth weight (below 2.6 kilos or 5lb 12oz). T ...
... Babies with a 22q12/13 duplication are often, but not always, small and underweight at birth with an average birth weight of 2.94 kg (6lb 8oz). The range of birth weights is between 1.3 kg (2lb 14oz) and 4.48 kg (9lb 14oz). However, half (5/10) had a low birth weight (below 2.6 kilos or 5lb 12oz). T ...
Not all mutant phenotypes are equally informative. Forward genetics
... Geneticists make mutations that disrupt normal gene functions (thereby creating a functional difference between alleles) to discover what genes do what ...
... Geneticists make mutations that disrupt normal gene functions (thereby creating a functional difference between alleles) to discover what genes do what ...
Mice 2 NZW)F Genetic Complementation in Female (BXSB ×
... loci for the Yaa⫹ BXSB (possibly four regions on chromosome 1, possibly two on chromosome 4, and a single locus each on chromosomes 3, 7, 8, 10, 13, 14, and 17) (10 –12). Although some of the overlapping loci from different strains may represent the same gene, it is evident from this and other studi ...
... loci for the Yaa⫹ BXSB (possibly four regions on chromosome 1, possibly two on chromosome 4, and a single locus each on chromosomes 3, 7, 8, 10, 13, 14, and 17) (10 –12). Although some of the overlapping loci from different strains may represent the same gene, it is evident from this and other studi ...
Full Paper - International Journal of Pharmaceutical Erudition
... XYY syndrome is a rare chromosomal disorder that affects males. It is caused by the presence of an extra Y chromosome. Males normally have one X and one Y chromosome. However, individuals with this syndrome have one X and two Y chromosomes. Affected individuals are usually very tall. Many experience ...
... XYY syndrome is a rare chromosomal disorder that affects males. It is caused by the presence of an extra Y chromosome. Males normally have one X and one Y chromosome. However, individuals with this syndrome have one X and two Y chromosomes. Affected individuals are usually very tall. Many experience ...
PDF-729K - ScienceCentral
... 9. This sex-ratio change is due to that majority of the stutters (>75%) resolve spontaneously, especially in females [7,8]. Therefore, the estimated prevalence of stuttering is about 1% in the general population. Consistent evidence for the involvement of genetic factors in stuttering has motivated ...
... 9. This sex-ratio change is due to that majority of the stutters (>75%) resolve spontaneously, especially in females [7,8]. Therefore, the estimated prevalence of stuttering is about 1% in the general population. Consistent evidence for the involvement of genetic factors in stuttering has motivated ...
PDF - Oxford Academic - Oxford University Press
... dominant optic neuropathy but no spasticity linked to the SPG7 locus. We identified two SPG7 mutations in 23/134 spastic patients, 21% of the patients selected according to phenotype but only 8% of those referred directly. Our results confirm the pathogenicity of Ala510Val, which was the most freque ...
... dominant optic neuropathy but no spasticity linked to the SPG7 locus. We identified two SPG7 mutations in 23/134 spastic patients, 21% of the patients selected according to phenotype but only 8% of those referred directly. Our results confirm the pathogenicity of Ala510Val, which was the most freque ...
Opsin genes, cone photopigments, color vision, and color blindness
... that the relative cone sensitivities depend on the relative numbers of the different cone types; namely, that 7% of all cones contain the S-cone pigment and that, of the remaining 93%, those containing the L-cone pigment are 1.5 times more frequent than those containing the M-cone pigment (see Chapt ...
... that the relative cone sensitivities depend on the relative numbers of the different cone types; namely, that 7% of all cones contain the S-cone pigment and that, of the remaining 93%, those containing the L-cone pigment are 1.5 times more frequent than those containing the M-cone pigment (see Chapt ...
multicopy gene family evolution on primate y chromosomes
... In the broadest sense, my thesis investigates two related questions: How are Y chromosomes different from autosomes?; and, Why are two Y chromosomes from different species often so dissimilar from one another, even when their autosomes are very similar? These questions have plagued geneticists and e ...
... In the broadest sense, my thesis investigates two related questions: How are Y chromosomes different from autosomes?; and, Why are two Y chromosomes from different species often so dissimilar from one another, even when their autosomes are very similar? These questions have plagued geneticists and e ...
PDF - Albinism Fellowship
... Nor does everyone with albinism have the stereotypical white skin and white hair with mauve eyes. The condition has a number of different variants (depending on which gene mutation has caused it) – and ‘hypopigmentation’ (where the skin becomes lighter because of problems with melanin production) in ...
... Nor does everyone with albinism have the stereotypical white skin and white hair with mauve eyes. The condition has a number of different variants (depending on which gene mutation has caused it) – and ‘hypopigmentation’ (where the skin becomes lighter because of problems with melanin production) in ...
LOCATION OF THE CENTROMERES ON THE LINKAGE
... may be determined from TI-9a which is known to be located in the short arm. On the basis of 730 plants, the percentage of crossing over between P and TI-ga was found to be 21.252.5. Thus the location of the centromere on the linkage map is 2 I . 2 units or more to the right of P. A number of translo ...
... may be determined from TI-9a which is known to be located in the short arm. On the basis of 730 plants, the percentage of crossing over between P and TI-ga was found to be 21.252.5. Thus the location of the centromere on the linkage map is 2 I . 2 units or more to the right of P. A number of translo ...
Genetic and epigenetic risks of intracytoplasmic sperm injection
... (PGD) is recommended for couples who are both positive for CF mutations and wish to integrate ICSI and genetic diagnosis at early stages of the embryonic development [21, 22]. Josserand et al. [23] detected CFTR mutations on 56 alleles of 50 males with congenital bilateral absence of vas deferens. A ...
... (PGD) is recommended for couples who are both positive for CF mutations and wish to integrate ICSI and genetic diagnosis at early stages of the embryonic development [21, 22]. Josserand et al. [23] detected CFTR mutations on 56 alleles of 50 males with congenital bilateral absence of vas deferens. A ...
Robust gene silencing mediated by antisense small RNAs in the
... amenable to silencing, (iii) the small hairpin RNA (shRNA) approach is labor intensive and (iv) reversal of gene silencing mediated by both double stranded RNA and shRNA has been reported (24) [W. A. Petri Jr. (personal communication)]. Additionally, little is known about the mechanism(s) of how the ...
... amenable to silencing, (iii) the small hairpin RNA (shRNA) approach is labor intensive and (iv) reversal of gene silencing mediated by both double stranded RNA and shRNA has been reported (24) [W. A. Petri Jr. (personal communication)]. Additionally, little is known about the mechanism(s) of how the ...
The population genetics of mutations: good, bad and indifferent
... It has often been said that mutations are random, a statement that is simultaneously true and false: true because mutations do not originate in any way or at any time that is related to whether their effects are beneficial—one of the central tenets of Neodarwinism; and false because mutations are th ...
... It has often been said that mutations are random, a statement that is simultaneously true and false: true because mutations do not originate in any way or at any time that is related to whether their effects are beneficial—one of the central tenets of Neodarwinism; and false because mutations are th ...
NON IMMUNE FETAL HYDROPS: An Overview
... (in cis) on each chromosome 16 (Table 1). There are α-thalassemia deletions that remove either one or two α-globin genes on each chromosome 16. If, both parents are carriers of a deletion removing two α-globin genes in cis on one chromosome 16, there is a one in four risk that in each pregnancy, the ...
... (in cis) on each chromosome 16 (Table 1). There are α-thalassemia deletions that remove either one or two α-globin genes on each chromosome 16. If, both parents are carriers of a deletion removing two α-globin genes in cis on one chromosome 16, there is a one in four risk that in each pregnancy, the ...
PDF
... thorax and abdomen. Animals bearing clones were dissected and mounted for examination at higher magnification. Since yf36a clones in the legs are not so easily detectable, all the legs from these animals were mounted and screened at high magnification for clones. All parts of flies irradiated at lat ...
... thorax and abdomen. Animals bearing clones were dissected and mounted for examination at higher magnification. Since yf36a clones in the legs are not so easily detectable, all the legs from these animals were mounted and screened at high magnification for clones. All parts of flies irradiated at lat ...
RT2 Profiler PCR Arrays: Pathway-focused gene
... Abstract: This paper evaluates the performance of the newest technique for monitoring the expression of a panel of pathway- or disease-specific genes: the RT2 Profiler PCR Array System. The RT2 Profiler PCR Array System combines the quantitative performance of SYBR® Green real-time PCR with the mult ...
... Abstract: This paper evaluates the performance of the newest technique for monitoring the expression of a panel of pathway- or disease-specific genes: the RT2 Profiler PCR Array System. The RT2 Profiler PCR Array System combines the quantitative performance of SYBR® Green real-time PCR with the mult ...
CROSSING-OVER IN DROSOPHILA is closer to a spindle fibre
... regions in the inverted section gave normal crossing-over. However, since in none of these cases of homozygous inversions did the inversion include regions close to the spindle fibre, the possibility remains that the spindle fibre influences crossing-over in regions close to it. Dobzhansky6 studied ...
... regions in the inverted section gave normal crossing-over. However, since in none of these cases of homozygous inversions did the inversion include regions close to the spindle fibre, the possibility remains that the spindle fibre influences crossing-over in regions close to it. Dobzhansky6 studied ...
View PDF - OMICS International
... with advanced reproductive age [1-3]. It was also suggested that meiosis II errors may, on the opposite, be a result of the increased meiotic recombination rate [4]. However, this was based not on the direct testing of meiosis errors, but limited to the testing of those products of conception that a ...
... with advanced reproductive age [1-3]. It was also suggested that meiosis II errors may, on the opposite, be a result of the increased meiotic recombination rate [4]. However, this was based not on the direct testing of meiosis errors, but limited to the testing of those products of conception that a ...
[PDF]
... the long perfect repeat number is <30, which is no longer than the normal mammalian Okazaki fragment length of 25–300 nucleotides; the long perfect repeat can be anchored by AGG interruptions. When the nascent strand contains >30 perfect repeats without an interruption as reference, the Okazaki frag ...
... the long perfect repeat number is <30, which is no longer than the normal mammalian Okazaki fragment length of 25–300 nucleotides; the long perfect repeat can be anchored by AGG interruptions. When the nascent strand contains >30 perfect repeats without an interruption as reference, the Okazaki frag ...
Saethre–Chotzen syndrome
Saethre–Chotzen syndrome (SCS), also known as Acrocephalosyndactyly type III is a rare congenital disorder associated with craniosynostosis (premature closure of one or more of the sutures between the bones of the skull). This affects the shape of the head and face, resulting in a cone-shaped head and an asymmetrical face. Individuals with SCS also have droopy eyelids (ptosis), widely spaced eyes (hypertelorism), and minor birth defects of the hands and feet (syndactyly). In addition, individuals with more severe cases of SCS may have mild to moderate mental retardation or learning disabilities. Depending on the level of severity, some individuals with SCS may require some form of medical or surgical intervention. Most individuals with SCS live fairly normal lives, regardless of whether medical treatment is needed or not.