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module 2: transcription part i
module 2: transcription part i

... a mature mRNA). Collectively, they constitute the transcription unit, the part of the gene that is read by RNA polymerase II during transcription. We use the name “transcription unit” rather than “gene” because genes also contain regulatory sequences (promoters and both positive and negative regulat ...
Monogenic Disorders
Monogenic Disorders

... carried by a gene called FBN1, which encodes a connective protein called fibrillin-1. This syndrome has a range of expressions, from mild to severe. The most serious complications are defects of the heart valves and aorta. In addition to being a connective protein that forms the structural support f ...
Gene Mutations
Gene Mutations

... makes proteins • If one or more amino acids are wrong, then the organism can’t build the correct proteins ...
A compact new computer program for handling nucleic acid se
A compact new computer program for handling nucleic acid se

... restriction enzyme data. The program contains a table of commercially or otherwise readily available, or seemingly interesting restriction enzyme cleavage sites; to date this includes 57 different restriction enzymes. The name of the appropriate restriction enzyme will be printed above the 5'-termin ...
No Slide Title
No Slide Title

... for galactose catabolism •Speeds induction of GAL genes ...
Intro (15min): finish Kahoots Activity #1 (30min): Short Answer
Intro (15min): finish Kahoots Activity #1 (30min): Short Answer

... 2. What  is  Mendel’s  law  of  independent  assortment?  What  biological  process   underlies  it  and  when  in  meiosis  does  the  process  occur?    Has  this  law  been   updated  to  take  into  account  post-­‐mendelian  genetics ...
10/9
10/9

... Totipotent: ability to differentiate into any cell-type ...
Rh antibodies
Rh antibodies

... There is one Rh locus at which occurs one Rh gene, but this gene has multiple alleles. For example, one gene R1 produces one agglutinogen (antigen) Rh1 which is composed of three "factors" The three factors are analogous to C, D, and e respectively The main difference between the Fisher-Race and Wie ...
File
File

... A mutant has been isolated that produces all three enzymes at the same level as induced cells do, even without any yuctose in the medium. ...
demystifying-genomics
demystifying-genomics

... corresponding to each of the few thousand genes that bacteria have can be placed on a single microarray in order to show, for instance,which are active during infections. That information could be useful in designing new antibiotics or other treatments. Current microarrays cannot accommodate all the ...
SPRGM Teacher Notes - 3D Molecular Designs
SPRGM Teacher Notes - 3D Molecular Designs

... Additional activities may include an exploration of the topic of newborn screening for genetic conditions and the ethical implications. 3. Inheritance Patterns Students use the Human Sepiapterin Reductase mRNA Gene Map© and other pedigrees to explore modes of inheritance of various traits and develo ...
Transmission Genetics
Transmission Genetics

... Transmission Genetics How traits are passed down from generation to generation.  Transmission of genes and the phenotypes which come from those genes  The phenotype determines how the individual interacts with the world, and it is the phenotype that is subject to natural selection. ...
BAD NEWS: THEY`RE ALL CARRIERS OF SOMETHING – BROKEN
BAD NEWS: THEY`RE ALL CARRIERS OF SOMETHING – BROKEN

... exome) sequencing of one or more individuals. Unlike most cells, gametes such as sperm or eggs contain only one copy of each of the 30 pairs of chromosomes. These single copies typically represent a chromosome that is not the same as either the paternal or maternal chromosome of the parent, but repr ...
Chapter 16: Chromosomal Basis of Inheritance
Chapter 16: Chromosomal Basis of Inheritance

... dominance, incomplete dominance, and co-dominance. 11. Describe the inheritance of the ABO blood system and explain why the IA and IB alleles are said to be co-dominant. 12. Define and give examples of pleiotropy and epistasis. Chapter 15: Chromosomal Basis of Inheritance Relating Mendelism to Chrom ...
Applied Biology Final Exam Review Sheet Exam: Friday (June 21st
Applied Biology Final Exam Review Sheet Exam: Friday (June 21st

... 8) Explain the sequence of events that must happen in order for a new species to form (speciation) 9) Explain the difference between geographic, temporal, and behavioral isolation and how these can lead to reproductive isolation and speciation Anatomy and Physiology – chp 35-39 and your homework wor ...
Genetic Code
Genetic Code

... Small molecules of 20 types that recognize and transfer amino acids for protein synthesis ...
Demystifying genomics - Medical Research Council
Demystifying genomics - Medical Research Council

... corresponding to each of the few thousand genes that bacteria have can be placed on a single microarray in order to show, for instance,which are active during infections. That information could be useful in designing new antibiotics or other treatments. Current microarrays cannot accommodate all the ...
Case Report
Case Report

... non-frameshift insertion of four new amino acids (QRQK) in the protein chain between amino acids 262-263. The new amino acids are located in the amino acid chain between the 'ion transport domain,' and 'domain of KCNQ1 voltage- gated potassium channel'. A program (Mutation Taster) helps to analyse t ...
Gene Duplication and Evolution
Gene Duplication and Evolution

... assertion that the vast majority of gene duplicates enjoy a rather short half-life, arguing that many ancient pairs of duplicates can be found in most eukaryotic genomes. In principle, the probability of loss of a duplicate gene may progressively decline once preservational events such as neofunctio ...
Genetics 2 - MaxSkyFan
Genetics 2 - MaxSkyFan

... • We salute you Mr. Gregor Mendel. An Austrian monk with a love for peas, you published data that showed blending inheritance was incorrect and introduced hereditary factors occurring in discrete pairs. ...
mutations that affect an entire chromosomes Chromosomal
mutations that affect an entire chromosomes Chromosomal

... • Mutations in body cells do not affect offspring. • Mutations in sex cells can be harmful or beneficial to offspring. • Natural selection often removes mutant alleles from a population when they are less adaptive. ...
Sequence analysis and expression of the M1 and M2 matrix protein
Sequence analysis and expression of the M1 and M2 matrix protein

... the partial ORFs of the N genes of HIRRV, IHNV, and VHSV are shown in Table 2. The nucleotide identities between HIRRV and the 2 strains of IHNV were higher than those between HIRRV and the 3 strains of VHSV that were analyzed, indicating that HIRRV was more closely related to IHNV than to VHSV. A C ...
Teacher Guide
Teacher Guide

... poly (A) tail, which can be used to purify the mRNA from the bulk of the cellular RNA. Cellular RNA can be passed over a column to which deoxythymidine (dT) residues have been attached. Poly (A) tail hybridizes to the oligo(dT), thus mRNA sticks to the column, the rest of the cellular RNA runs throu ...
Transcription Factor binding site analysis
Transcription Factor binding site analysis

... Nat Rev Genet. 2010 Nov;11(11):751-60. Epub 2010 Sep 28. Determining the specificity of protein-DNA interactions. ...
SBARS: fast creation of dotplots for DNA sequences on different
SBARS: fast creation of dotplots for DNA sequences on different

... The vast majority of approaches used to analyze nucleotide and amino acid sequences are based on algorithms working with text strings. Until recently, such methods were justified because the length of processed genetic text was relatively short. The evolution of sequencing techniques, however, has r ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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