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OCR GCSE (9-1) Gateway Science Biology A
OCR GCSE (9-1) Gateway Science Biology A

... Learner resource 3 – Mitosis demonstration with shoes This is an alternative method to allow students to visualise mitosis. It is easy to resource and is technically easy. This step-by-step guide is written for teachers who are not biologists. Mitosis is a process that produces two genetically ident ...
Keio Mutation Database (KMDB) for human
Keio Mutation Database (KMDB) for human

... In the default of the ‘Gene structure’ window, mutations are displayed along the genomic structure of the gene. Various types of mutations are listed in the ‘Symbol table’ (Fig. 3, upper right) which pops-up through the help menu. Each mutation symbol on the X-axis locates exactly on the mutation si ...
CGC07OthrGene - Cucurbit Breeding
CGC07OthrGene - Cucurbit Breeding

... cucumber, melon and watermelon. Those are major crop species originally from the Old World: cucumber from India; melon and watermelon from Africa (Wehner and Maynard, 2003). However, there are other important species originally from Africa such as gherkin (Cucumis anguria), African horned melon (Cuc ...
Ш Problem 1 pleiotropic (multiple traits affected) sex
Ш Problem 1 pleiotropic (multiple traits affected) sex

... and phenocopy in your text, relevant lecture material & the Genomes Unzipped reading assignment. The term genetic heterogeneity is used to describe situations where mutations in different genes can result in similar phenotypes. Ì Problem 4 a. pleiotropic Ì Problem 5 Most obvious feature of this pe ...
Section 14. Pedigree Analysis and Molecular Markers
Section 14. Pedigree Analysis and Molecular Markers

... Problem: the identical twins in generation II, and III 2 and 3, must have dominant allele, must have got from one or other parent, so one of their parents would have to be albino. Internal contradiction. ...
Chapter 2 – Alleles at a Single Locus
Chapter 2 – Alleles at a Single Locus

... A specific position along a chromosome is called a locus. Because each gene occupies a specific locus along a chromosome, the terms locus and gene are often used interchangeably. However, the term “gene” is a much more general term, while “locus” usually is limited to defining the position along a c ...
tAIg = w
tAIg = w

... them to have a threefold difference in translation rate (21.6 and 6.4 codons per second, respectively). Remarkably, the wi of these codons, which is based on the tRNA pool and affinity of codon-anti-codon coupling and is the basis for the tAI calculation, captures the ratio of translation rate betwe ...
DNA
DNA

meiosis_9_for_VLE
meiosis_9_for_VLE

... if the genes interact with each other through a mechanism such as epistasis In discontinuous variation, each allele will have a large effect on the phenotype Different gene loci may have very different effects on the phenotype Dominant, codominant and recessive alleles may be involved ...
Lab # 6
Lab # 6

... breeders have bred Siamese cats to be extremely thin with wedge-shaped heads and Persians to be rounder (cobbier) with large heads and small almost non-existent noses. If you look at pictures of Siamese cats or Persian cats from 100 years ago their shape is quite similar with none of the extreme bod ...
Caco-2 cell culture and DNA transfection
Caco-2 cell culture and DNA transfection

... gastroenteritis both in the US and worldwide. Currently, a vaccine is not available, but several vaccine strategies target the norovirus capsid protein encoded by the open reading frame 2 (ORF-2). Recombinant norovirus capsid protein can selfassemble into virus-like particles (VLP) that are antigeni ...
DQ handout
DQ handout

... likely do not possess neural nets that are as highly structured, but I imagine that they are equally as important as hormones in regulating plastic responses to environmental variability, albeit on a different temporal scale. In light of this issue, what other aspects of organismal function may be c ...
WALT: Is aggression inherited?
WALT: Is aggression inherited?

... There are a large number of accessible studies and a key feature will be the extent to which findings are appropriately interpreted and developed into a line of argument. Methodological evaluation of studies may only earn AO2/3 marks if the implications for the reliability/validity of findings in re ...
Lecture 18: Lecture 18: Gene Expression II: From RNA to Protein
Lecture 18: Lecture 18: Gene Expression II: From RNA to Protein

IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) ISSN: 2278-3008.
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) ISSN: 2278-3008.

... Role of epigenetic modifications in stem cell regulatory regions (Oct4, Sox2 and Nanog) and cancer this reaction as a methyl group donor and also DNA methyltransferases (DNMT) play role in it [7]. DNA methylation, in alliance with histone adaptation is an indispensable constituent of the epigenetic ...
View PDF
View PDF

... 1. Genetics is the study of biological _________________ patterns and variation in organisms. 2. A man named Gregor ___________________ did early work that is the basis for much of our current understanding of genetics. 3. Mendel’s views on inheritance differed from the views of many scientists of h ...
Non-directed Modification of Genome Cont.. - PMAS
Non-directed Modification of Genome Cont.. - PMAS

... palindromic repeat) system/CRISPR-associated protein 9 nuclease (Cas9). ...
CHAPTER 15 THE CHROMOSOMAL BASIS OF INHERITANCE
CHAPTER 15 THE CHROMOSOMAL BASIS OF INHERITANCE

... Section A: Relating Mendelism to Chromosomes 1. Mendelian inheritance has its physical basis in the behavior of chromosomes during sexual life cycles 2. Morgan traced a gene to a specific chromosome 3. Linked genes tend to be inherited together because they are located on the same chromosome 4. Inde ...
DNA Dots - miniPCR
DNA Dots - miniPCR

... cells also have a different DNA repair mechanism that can sometimes mend the cut according to a DNA template. This process is called homology directed repair. If we provide the repair template, then we might get to change a target gene to our specifications. That’s exactly what scientists have learn ...
UCSC Known Genes (by Jim Kent)
UCSC Known Genes (by Jim Kent)

... • Last intron more than 55 bases past stop codon ...
Homework set 4
Homework set 4

... (h) (15%) Compose a family tree in which there are two nodes in your network, call then A and B, which are analogous to the Gas and Radio on page 445. In particular, you should be able to exercise all four cases mentioned (there are two cases in case 3 of the example.) Confirm the independence assum ...
Protein synthesis
Protein synthesis

... polypeptide chains  Many polypeptide chains are covalently modified, either while they are still attached to the ribosome (cotranslational) or after their synthesis has been completed (posttranslational).  These modifications may include removal of part of the translated sequence, or the covalent ...
Cloning and characterization of a gene coding for a hydrophobin Fv
Cloning and characterization of a gene coding for a hydrophobin Fv

... Some mushrooms contain unique metabolites with antitumor or immunomodulating activity and have been used as medicine. Moreover, basidiomycetes have an ability to degrade lignin and cellulose in wood and have been examined for utilization in biomass conversion (Kues and Liu 2000). At present, only li ...
Biology Slides
Biology Slides

...  Leads to aneuploidy or polyploidy within gametes  Aneuploidy – having one extra chromosome or missing one chromosome  Extreme cases can result in total non-disjunction, where all homologous pairs fail to separate Total non-disjunction ...
Genetic Disorders
Genetic Disorders

... A karyotype is simply a picture of a person's chromosomes. In order to get this picture, the chromosomes are isolated, stained, and examined under the microscope. Most often, this is done using the chromosomes in the white blood cells. A picture of the chromosomes is taken through the microscope. ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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