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Genetic Heterogeneity in Human Disease. McCellan and King. 2010
Genetic Heterogeneity in Human Disease. McCellan and King. 2010

... including cytoskeleton, adhesion, scaffolding, and motor proteins (red); ion homeostasis, including connexins, ion channels, and tight junctions (blue); extracellular matrix proteins (green), transcription factors (orange), and proteins whose function in hearing is not yet known (black). Every gene ...
Genetic Carrier Testing for CF
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genetics
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... the blood. A and B are antigens (flags) on the blood that will be recognized. If the antigen is unfamiliar to the body, your body will attack and destroy the transfused blood as if it were a hostile invader (which can cause death). • O is like a blank, it has no antigens. O is called the universal d ...
ch 12 quick check answers
ch 12 quick check answers

... True: DNA profiles based on chromosomal DNA give far more precise identification than that obtained using mitochondrial DNA (mtDNA). This occurs because mtDNA is inherited generation after generation without recombination from maternal ancestors, while STRs undergo reassortment during meiosis at eve ...
ap15-ChromosomalBasisofInheritance 07-2008
ap15-ChromosomalBasisofInheritance 07-2008

... chromosomes (effect often less severe) • usually occurs when a normal gamete fertilizes another gamete in which there has been nondisjunction of all its chromosomes – produces a triploid (3n) zygote (2n + 1n) ...
Immunogenetics
Immunogenetics

...  Why did the amino acid sequencing of antibody light chains lead Dryer and Bennet to abandon the one gene- one polypeptide theory and propose that two genes code for a single polypeptide? ...
Genetics and Heredity
Genetics and Heredity

...  The alleles are either dominant or recessive.  To show the recessive trait, two recessive alleles must be inherited. ...
Molecular Genetics
Molecular Genetics

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Notes - Haiku Learning
Notes - Haiku Learning

... 1. Polymerase chain reaction (PCR): uses fragments of DNA and produces a large number of copies and then denatured (separated in single strands) by heating to 92 °-94° C a) Can be studied and analyzed and often used in forensics when a limited amount of DNA has been recovered b) Thermus aquaticus (T ...
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The Human Chromosome
The Human Chromosome

... Your body contains two types of chromosomes: sex chromosomes and autosomal chromosomes. Sex chromosomes determine whether you are male or female.  Autosomes determine every other trait in your body from the color of your eyes, to how fast your metabolism is. ...
Appendix 1 - HUGO Gene Nomenclature Committee
Appendix 1 - HUGO Gene Nomenclature Committee

... nomenclature of known gene, .e.g ADAL (adenosine deaminase like). If gene is an ortholog of a gene with known function in another species assign appropriate symbol with “homolog” included in the gene name e.g. CDC6 (cell division cycle 6 homolog). ...
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TatD Is a Cytoplasmic Protein with DNase Activity
TatD Is a Cytoplasmic Protein with DNase Activity

... unassigned and unlinked genes ycfH (29% amino acid sequence identity) and yjjV (24% amino acid sequence identity). Because these additional TatD homologues may be capable of functionally substituting for TatD, we have also examined the phenotype of a strain in which all three genes coding for TatD-l ...
CHAPTER 5 - U of L Class Index
CHAPTER 5 - U of L Class Index

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StuartBrown-Teaching

... gene expression, regulatory and metabolic modeling Computational biology - the design of new algorithms and software to support biology research The routine use of computers in all phases of biology and medicine ...
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dragon genetics lab
dragon genetics lab

... 6. The decoding chart on page 2 indicates the phenotypic effect of each gene on the baby. The trait produced by each pair of alleles should be recorded in the data chart. Remember that a CAPITAL letter is dominant over a small letter [recessive] unless the decoding chart indicates those traits are c ...
Organic Chemistry Fifth Edition
Organic Chemistry Fifth Edition

... This complementary RNA is messenger RNA (mRNA). Mechanism of transcription resembles mechanism of DNA replication. Transcription begins at the 5' end of DNA and is catalyzed by the enzyme RNA polymerase. ...
A protein-based phylogenetic tree for Gram
A protein-based phylogenetic tree for Gram

... The dnaK operon from Bacillus subtilis and other Gram-positive bacteria with low G+C DNA content contains additional heat-shock genes, including hrcA. The hrcA gene encodes a transcription factor that negatively regulates heatshock genes and is uniformly present in all Gram-positive bacteria studied ...
Mendel’s Peas - rcschools.net
Mendel’s Peas - rcschools.net

... CLE 3210.4.1 Investigate how genetic information is encoded in nucleic acids. CLE 3210.4.2 Describe the relationships among genes, chromosomes, proteins, and hereditary traits. CLE 3210.4.3 Predict the outcome of monohybrid and dihybrid crosses. ...
RNA polymerase II is the key enzyme in the process of transcription
RNA polymerase II is the key enzyme in the process of transcription

... All questions are given in English, but you may choose yourself in which language (Norwegian or English) you prefer to answer. This exam consists of two parts. The first part is a set of questions, where you are supposed to provide brief and concise answers through a few phrases only (less than 10 p ...
Gene7-10
Gene7-10

... Allosteric control refers to the ability of an interaction at one site of a protein to influence the activity of another site. Coordinate regulation refers to the common control of a group of genes. Corepressor is a small molecule that triggers repression of transcription by binding to a regulator p ...
TARGETING YOUR DNA WITH THE CRE/LOX SYSTEM
TARGETING YOUR DNA WITH THE CRE/LOX SYSTEM

... For a gene to produce a protein it requires a ‘promoter.’ This is a section of DNA in front of the gene that functions to recruit the cellular machinery that will initiate the multi-step process of protein production (called gene expression). How the promoter functions to do this can vary, from alwa ...
Quantitative genetics and breeding theory
Quantitative genetics and breeding theory

... Some properties of status number • NS can never be higher than the census number (N); q NS can never be lower than 0.5 (NS of a gamete); q NS considers relatedness and inbreeding; q NS may be derived for any hypothetical population (with known relatedness patterns to a known source population). It ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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