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Created with Sketch. Family resemblance traits through generations
Created with Sketch. Family resemblance traits through generations

... organisms pass on genes by duplicating their genetic information and then splitting to form an identical organism. More complex organisms, including humans, produce specialised sex cells (gametes) that carry half of the genetic information, then combine these to form new organisms. The process that ...


... 1) Visualize fitness as a function of gene function for one and two genes with and without pleiotropy 2) Construct and explain a plausible model for the evolution of increased complexity 3) Describe and discuss the role of gene duplication and pleiotropy in the evolution of complexity 4) Infer the h ...
X chromosome
X chromosome

... Inactivation of X-linked Genes in Female Mammals Cytological studies have identified human beings with more than two X chromosomes (see Chapter 6). For the most part, these people are phenotypically normal females, apparently because all but one of their X chromosomes is inactivated. Often all the ...
Physical Mapping of Important Trait Loci in the Pig
Physical Mapping of Important Trait Loci in the Pig

... The nuclear DNA in mitotic cells is highly condensed and can be visualized in light microscope as chromosomes. DNA molecules are long chains, the backbone being composed of deoxyribose phosphate units joined to each other through phosphodiester bonds, attached to each deoxyribose is one of four nitr ...
08_chapter 1
08_chapter 1

... existence provides some explanation for Chargaffs 2"d parity. Forsdyke and Mortimer (2000) concluded that organisms that had accepted point mutations which increased the probability of stem-loop formation (both in protein-coding and in non-protein-coding DNA), had usually had an evolutionary advanta ...
AP Biology
AP Biology

... spontaneous mutations  for 1 gene, only ~1 mutation in 10 million replications  each day, ~2,000 bacteria develop mutation in that ...
Novel Roles for Selected Genes in Meiotic DNA Processing
Novel Roles for Selected Genes in Meiotic DNA Processing

... minimally characterized genes involved in meiotic DNA processing. Based on our selection procedure, 81 deletion mutants were constructed and tested for phenotypic abnormalities. Eleven (13.6%) genes were identified to have novel roles in meiotic DNA processes including DNA replication, recombination ...
Ch. 21
Ch. 21

... • About 24% of the human genome codes for introns and gene-related regulatory sequences • Intergenic DNA is noncoding DNA found between genes – Pseudogenes are former genes that have accumulated mutations and are nonfunctional – Repetitive DNA is present in multiple copies in the genome ...
Table 3.1. List of suppliers of restriction enzymes. Name of
Table 3.1. List of suppliers of restriction enzymes. Name of

... Resistance to ampicillin (Ampr), tetracycline (Tet1), erythrdmycine (EryO* streptomycine (Strr), Kanamycin (Kanr), rifampicin (Rifr), and colicin production (EL imm.) A physical map of plasmid pBR 322 is shown in ( Fig. 3.4.) The pBR 322 is constructed from the plasmids of E. coli,pBR318 and pBR320. ...
Identification of a novel streptococcal gene cassette mediating
Identification of a novel streptococcal gene cassette mediating

... autocatalytic cleavage of the Ala84-Gly85 bond of LexA, which disrupts its ability to dimerize (35, 57). Self-cleavage of LexA inactivates LexA as a repressor, which induces the expression of SOS genes. SOS mutagenesis is mainly mediated by errorprone polymerases and takes place under severe conditi ...
SEGMENTAL VARIATION
SEGMENTAL VARIATION

... deal of human phenotypic variability including disease • Depth-of-coverage methods can detect many CNVs but not inversions and translocations. Variation from sample to sample limits sensitivity and specificity. ...
Protein synthesis - World of Teaching
Protein synthesis - World of Teaching

... mRNA copy is made of one of the DNA strands. mRNA copy moves out of nucleus into cytoplasm. tRNA molecules are activated as their complementary amino acids are attached to them. mRNA copy attaches to the small subunit of the ribosomes in cytoplasm. 6 of the bases in the mRNA are exposed in the ribos ...
Tumor Viruses
Tumor Viruses

... c. Another way: they can insert themselves so that their promoter can transcribe a proto-oncogene and turn it “on” at the wrong time. d. A third way: altering the transcription of the gene by putting in different splice sites, resulting in hybrid RNAs that live longer in the cell (leading to over-pr ...
Leukaemia Section t(11;19)(q23;p13.1) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(11;19)(q23;p13.1) Atlas of Genetics and Cytogenetics in Oncology and Haematology

... Children and, most often, adults (7 days to 83 yrs); congenital cases are rare, in contrast with the t(11;19)(q23;p13.3) leukaemia; balanced sex ratio. Clinics Organomegaly in half cases; CNS involvement in some cases. Treatment BMT is indicated. Prognosis Very poor (median: 6 mths!). ...
Axelrod_Prisoners_Dilemma_Notes
Axelrod_Prisoners_Dilemma_Notes

Exam 2 (pdf - 449.81kb)
Exam 2 (pdf - 449.81kb)

... D. guanine nucleotides equals the number of uracil nucleotides. Question 9 During DNA replication A. messenger RNA (mRNA) is produced. B. reverse transcriptase enzymes play an important role. C. bonds between phosphate and sugar molecules break. D. each of the DNA strands acts as a template strand. ...
Evolution review!
Evolution review!

... A mouse skin cell contains 40 chromosomes. Based on this information, how many chromosomes would a mouse SPERM cell contain? ...
1 Antibiotic susceptibility Antibiotic: natural chemicals produced by
1 Antibiotic susceptibility Antibiotic: natural chemicals produced by

... 1. Defined genetic entities 2. Found in bacteria 3. Have their own genes which allow them to move from one place on a DNA molecule to a new place within the same cell (transposition) 4. Carry their own genes to allow movement from one cell to another by conjugation 5. Located on chromosomes or occas ...
PDF
PDF

... were transformed into L. plantarum. Growth of the transformants in the absence of the selection pressure, erythromycin (both plasmids confer Emr), led to a stable sub-population of Emr bacteria in which pSA3 and p JR1 had integrated into the L. plantarum genome. Amplification of the chromosomally lo ...
(protein) 1. - St John Brebeuf
(protein) 1. - St John Brebeuf

... mRNA copy is made of one of the DNA strands. mRNA copy moves out of nucleus into cytoplasm. tRNA molecules are activated as their complementary amino acids are attached to them. mRNA copy attaches to the small subunit of the ribosomes in cytoplasm. 6 of the bases in the mRNA are exposed in the ribos ...
biology syllabus - prakashamarasooriya
biology syllabus - prakashamarasooriya

... State that DNA replication is initiated at many points in eukaryotic chromosomes. ...
Glorious Genetics with a Marvelous Monk Named Mendel
Glorious Genetics with a Marvelous Monk Named Mendel

... heterozygous (Aa) for purple color. What is the chance of getting a white (aa) offspring?  Chance of plant 1 giving a = ½  Chance of plant 2 giving a = ½  Chance of white offspring aa = ¼  Does it work??? Do the square to confirm ...
Slide 1
Slide 1

... 9.1 The science of genetics has ancient roots  Pangenesis was an early explanation for inheritance • It was proposed by Hippocrates • Particles called pangenes came from all parts of the organism to be incorporated into eggs or sperm • Characteristics acquired during the parents’ lifetime could be ...
Glorious Genetics with a Marvelous Monk Named
Glorious Genetics with a Marvelous Monk Named

... heterozygous (Aa) for purple color. What is the chance of getting a white (aa) offspring?  Chance of plant 1 giving a = ½  Chance of plant 2 giving a = ½  Chance of white offspring aa = ¼  Does it work??? Do the square to confirm ...
CHAPTER 4 Gene Function
CHAPTER 4 Gene Function

... iii. biotin (a vitamin). g. To grow on minimal media, wild-type Neurospora synthesizes all organic molecules it needs for growth. An auxotrophic mutant unable to make a needed nutrient will only grow if that nutrient is provided as a supplement in its medium. ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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