Characterization of two rice DNA methyltransferases
... cytosine-5 DNA methyltransferase (MTase), were isolated from rice (Oryza sativa L.) BAC libraries. OsMET1-1 has an open reading frame of 4,566 nucleotides with twelve exons and eleven introns while OsMET1-2 has an open reading frame of 4,452 nucleotides with eleven exons and ten introns. Although Os ...
... cytosine-5 DNA methyltransferase (MTase), were isolated from rice (Oryza sativa L.) BAC libraries. OsMET1-1 has an open reading frame of 4,566 nucleotides with twelve exons and eleven introns while OsMET1-2 has an open reading frame of 4,452 nucleotides with eleven exons and ten introns. Although Os ...
Shastry, B.S. 2002. SNP alleles in human disease and evolution
... to include some differences or variations in the genome between individuals. This variation, called polymorphism, arises because of mutations. The simplest form of these variations is the substitution of one single nucleotide for another (Fig. 1A), termed SNP. SNPs are more common than other types o ...
... to include some differences or variations in the genome between individuals. This variation, called polymorphism, arises because of mutations. The simplest form of these variations is the substitution of one single nucleotide for another (Fig. 1A), termed SNP. SNPs are more common than other types o ...
Reassembled Biosynthetic Pathway for Large
... achieves the same goal with the use of only one plasmid and a single strain. All the enzymes essential for oligosaccharide synthesis, including the glycosyltransferases, and the sugar ± nucleotide regeneration are in one E. coli strain. Thus, this approach avoids unnecessary transport of the interme ...
... achieves the same goal with the use of only one plasmid and a single strain. All the enzymes essential for oligosaccharide synthesis, including the glycosyltransferases, and the sugar ± nucleotide regeneration are in one E. coli strain. Thus, this approach avoids unnecessary transport of the interme ...
Study protocol to investigate the environmental and genetic
... Thank you very much for your comment to make the harmonisation of the ongoing harmonisation of AD diagnosis criteria. It is great idea to include these items. At this time being we will take as much information as we can including weight, height, head circumference, skin fold thickness (adiposity) t ...
... Thank you very much for your comment to make the harmonisation of the ongoing harmonisation of AD diagnosis criteria. It is great idea to include these items. At this time being we will take as much information as we can including weight, height, head circumference, skin fold thickness (adiposity) t ...
Influence of industrial contamination on mobile genetic elements
... detected MGEs including plasmids, transposons and integrons across a wide variety of habitats (for example, Sobecky, 1999; Smalla and Sobecky, 2002; van Elsas and Bailey, 2002; Frost et al., 2005), but rarely in a quantitative manner due to previous methodological constraints. In those studies that ...
... detected MGEs including plasmids, transposons and integrons across a wide variety of habitats (for example, Sobecky, 1999; Smalla and Sobecky, 2002; van Elsas and Bailey, 2002; Frost et al., 2005), but rarely in a quantitative manner due to previous methodological constraints. In those studies that ...
miRNA pptx - NUS School of Computing
... One miRNA transcript can only degrade one mRNA transcript Thus miRNA expression changes should not be much different from mRNA expression changes ...
... One miRNA transcript can only degrade one mRNA transcript Thus miRNA expression changes should not be much different from mRNA expression changes ...
Graphical Exploration of Gene Expression Data: A
... matrix A is obtained whose elements aij = log xij . For this operation to be valid, measurements must be made on a ratio scale and the values must be positive. Logarithmic re-expression allows data in different physical units to be compared to one another as the logarithm of their ratios. In additio ...
... matrix A is obtained whose elements aij = log xij . For this operation to be valid, measurements must be made on a ratio scale and the values must be positive. Logarithmic re-expression allows data in different physical units to be compared to one another as the logarithm of their ratios. In additio ...
Parallel Analysis of Gene Expression: Microarrays
... or perform a contrast, and how to lay out the hybridizations, is always advisable, since the way an experiment is performed can have a large effect on statistical power and hence the conclusions that are reached. There are at least a half dozen different common applications of microarray methodology ...
... or perform a contrast, and how to lay out the hybridizations, is always advisable, since the way an experiment is performed can have a large effect on statistical power and hence the conclusions that are reached. There are at least a half dozen different common applications of microarray methodology ...
Marker-based inferences about fecundity genes contributing
... fecundity genes contributing to inbreeding depression have small effects. However, the proportion of phenotypic variation explained by all significant segments can be large ( u p to 11.32%). Considering that about 11.2% of the M. guttatus g e n o m e was marked by the seven markers in F,,, these res ...
... fecundity genes contributing to inbreeding depression have small effects. However, the proportion of phenotypic variation explained by all significant segments can be large ( u p to 11.32%). Considering that about 11.2% of the M. guttatus g e n o m e was marked by the seven markers in F,,, these res ...
Six3, a murine homologue of the sine oculis gene, demarcates the
... In the initial screening of an E8.5 mouse cDNA library using the Drosophila so homeobox-containing gene, two novel murine genes of this type were identified and named Six1 and Six2 (Oliver et al., 1995). The expression of these genes was found to be restricted mainly to head and body mesenchyme, lim ...
... In the initial screening of an E8.5 mouse cDNA library using the Drosophila so homeobox-containing gene, two novel murine genes of this type were identified and named Six1 and Six2 (Oliver et al., 1995). The expression of these genes was found to be restricted mainly to head and body mesenchyme, lim ...
General background text Pharmacogenetics
... located in the genes, in the DNA that consists of nucleotides. The piece of the DNA that carries information for one specific hereditary characteristic is called a gene. The DNA is divided into chromosomes, which usually occur in pairs. This means that an individual has two copies (two alleles) of m ...
... located in the genes, in the DNA that consists of nucleotides. The piece of the DNA that carries information for one specific hereditary characteristic is called a gene. The DNA is divided into chromosomes, which usually occur in pairs. This means that an individual has two copies (two alleles) of m ...
2005-05_Purdue_edimmer
... Huge body of knowledge with an extremely large vocabulary to describe it ...
... Huge body of knowledge with an extremely large vocabulary to describe it ...
Background Selection in Single Genes May Explain
... may exert significant effects on sites within the same or neighboring genes. The basis for this can be understood as follows. Published data on autosomal DNA sequence polymorphisms in regions with normal recombination rates in African populations of Drosophila melanogaster yield a mean nonsynonymous ...
... may exert significant effects on sites within the same or neighboring genes. The basis for this can be understood as follows. Published data on autosomal DNA sequence polymorphisms in regions with normal recombination rates in African populations of Drosophila melanogaster yield a mean nonsynonymous ...
Ingenuity Upstream Regulator Analysis in IPA®
... that can explain the observed gene expression changes in a user’s dataset, which can help illuminate the biological activities occurring in the tissues or cells being studied. IPA makes it easy to take this result even further by examining what biological processes, pathways, and diseases the tra ...
... that can explain the observed gene expression changes in a user’s dataset, which can help illuminate the biological activities occurring in the tissues or cells being studied. IPA makes it easy to take this result even further by examining what biological processes, pathways, and diseases the tra ...
Lesson 66 Pedigree Packet KEY 66 STT and
... c. Because the blue-tail appears the same for TT or Tt, and each parent can pass a T or a t, we don’t know the genpotype by looking at the pedigree. Learning from Data on Human Conditions 2. PKU is likely to be recessive since parents that do not have it, Produce offspring with it. The parents are “ ...
... c. Because the blue-tail appears the same for TT or Tt, and each parent can pass a T or a t, we don’t know the genpotype by looking at the pedigree. Learning from Data on Human Conditions 2. PKU is likely to be recessive since parents that do not have it, Produce offspring with it. The parents are “ ...
A simple set of rules for primer sequence design is as follows
... sequester the cation; of these, dNTPs are the most concentrated, so [Mg2+] should be 0.5 2.5mM greater than [dNTP]. A titration should be performed with varying [Mg2+] with ...
... sequester the cation; of these, dNTPs are the most concentrated, so [Mg2+] should be 0.5 2.5mM greater than [dNTP]. A titration should be performed with varying [Mg2+] with ...
A method for finding molecular signatures from gene expression data
... A possible definition: “(...) a group of genes expressed in a specific cell lineage or stage of differentiation or during particular biological response.” (Rosenwald et al., 2002, N. Eng. J. Med., 346, p. 1942) Often used as independent variables to model clinically relevant information (cancer vs. ...
... A possible definition: “(...) a group of genes expressed in a specific cell lineage or stage of differentiation or during particular biological response.” (Rosenwald et al., 2002, N. Eng. J. Med., 346, p. 1942) Often used as independent variables to model clinically relevant information (cancer vs. ...
Ensembl Genome Browser - molecularevolution.org
... cDNAs or mRNAs from related species Expression array probe set mapping ...
... cDNAs or mRNAs from related species Expression array probe set mapping ...
B M B 400 Part Four
... An important negative control is the annealing to a labeled ovalbumin gene probe, a gene that is not expressed in either liver or red cells (only oviduct). In this case, the DNA from partially digested nuclei from both tissues annealed with the same kinetics to the ovalbumin probe. Thus there is no ...
... An important negative control is the annealing to a labeled ovalbumin gene probe, a gene that is not expressed in either liver or red cells (only oviduct). In this case, the DNA from partially digested nuclei from both tissues annealed with the same kinetics to the ovalbumin probe. Thus there is no ...
Nomenclature for incompletely specified bases in nucleic acid
... cleavage sites of restriction endonucleases. For instance, the cleavage specificity of the common enzyme EcoRI might be represented by G/AATTC, where cleavage occurs in both strands of the self-symmetrical sequence between the G and A residues. ...
... cleavage sites of restriction endonucleases. For instance, the cleavage specificity of the common enzyme EcoRI might be represented by G/AATTC, where cleavage occurs in both strands of the self-symmetrical sequence between the G and A residues. ...
The linear chromosome of the plant
... assigned to the novel provisional genus Candidatus Phytoplasma [2]. They represent a monophyletic group within the class Mollicutes (trivial name mycoplasmas), which has evolved from Gram-positive bacteria [3]. Mycoplasmas are among the smallest self-replicating organisms known, and are characterize ...
... assigned to the novel provisional genus Candidatus Phytoplasma [2]. They represent a monophyletic group within the class Mollicutes (trivial name mycoplasmas), which has evolved from Gram-positive bacteria [3]. Mycoplasmas are among the smallest self-replicating organisms known, and are characterize ...
Mitochondriontoplastid DNA transfer: it happens
... Complicating the story is that DcMP, apart from having a short cox1-like segment, shows little similarity to other sequences in GenBank, making it difficult to trace its origin within the Apiaceae, and leaving open the possibility that it began in the nuclear compartment and was then transferred ind ...
... Complicating the story is that DcMP, apart from having a short cox1-like segment, shows little similarity to other sequences in GenBank, making it difficult to trace its origin within the Apiaceae, and leaving open the possibility that it began in the nuclear compartment and was then transferred ind ...
Genetic Contribution to Coronary Atherosclerosis
... causative/susceptibility genes, and that there would be different subset of secondary genes involved in coronary plaque initiation, progression and destabilization. Genes detected in human coronary plaques or identified to alter plaque burden in mouse gene knockout studies would be classified as sec ...
... causative/susceptibility genes, and that there would be different subset of secondary genes involved in coronary plaque initiation, progression and destabilization. Genes detected in human coronary plaques or identified to alter plaque burden in mouse gene knockout studies would be classified as sec ...
![PA ALKF-[FY]-[STA]-[STAD]-[VM]](http://s1.studyres.com/store/data/002279064_1-5287fab8d5ca72543328286b23cc5a55-300x300.png)
PA ALKF-[FY]-[STA]-[STAD]-[VM]
... Databases are of course the core resource for bioinformatics. There is plenty of software for analysing one or a few sequences, but many of the computationally interesting and biologically informative programs access databases of information. Frequently used are the biological sequence databases. Th ...
... Databases are of course the core resource for bioinformatics. There is plenty of software for analysing one or a few sequences, but many of the computationally interesting and biologically informative programs access databases of information. Frequently used are the biological sequence databases. Th ...
Gene
A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.