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Plant Molecular Biology
Plant Molecular Biology

... recognize and interact with degradation substrates, and in this way are responsible for the specificity of protein degradation by the ubiquitin pathway (Hershko and Ciechanover, 1998). This pathway regulates key biological processes, such as cell division, metabolism, immune response, and apoptosis. ...
Molecular basis for the deficiency in humans of gulonolactone
Molecular basis for the deficiency in humans of gulonolactone

... it should be noted from inspection the intensities of the signals for human ...
Hemophilia
Hemophilia

... transmitted to the siblings. (Picture). When the father ihas a hemophilia, all of his daughters would be carriers, while none of his sons would have hemophilia. ...
The Effect of a Coat Colour-Associated Genes Polymorphism on
The Effect of a Coat Colour-Associated Genes Polymorphism on

... dominant homozygote (RnRn) is lethal in utero (Thiruvenkadan et al., 2008). Linkage analysis between KIT and the RN, performed by Marklund et al. (1999), showed strong linkage (no recombinantion was observed). Additionally a 79 base pairs insertion between exons 1 and 2 of the KIT gene (frameshift m ...
- The Boyle Lab
- The Boyle Lab

... information onto any set of variants derived from genomic sequencing or GWAS studies. These efforts demonstrate which variants have potential or demonstrated regulatory functions and through which mechanisms those functions might work. To generate these functional assignments, we make use of large s ...
Monohybrid Cross Problems
Monohybrid Cross Problems

... Biology Chapter 11 Introduction Monohybrid Cross Worksheet ...
A novel environment-sensitive biodegradable polydisulfide with
A novel environment-sensitive biodegradable polydisulfide with

Pearl millet, food for the future in the Sahel
Pearl millet, food for the future in the Sahel

... and also certain morphological traits such as spike length and stem diameter. Flowering time was strongly linked to climatic conditions: a long flowering time was better adapted to more humid climates, a shorter one suitable for drier conditions. For example, the species cultivated in coastal tropic ...
You Light Up My Life
You Light Up My Life

Document
Document

...  Heritable changes can result in a useful novel phenotype, i.e., a new allele. ...
Chapter 5 Gases - Saint Demetrios Astoria School
Chapter 5 Gases - Saint Demetrios Astoria School

Receptor Gene in a Patient with GH Insensitivity Syndrome
Receptor Gene in a Patient with GH Insensitivity Syndrome

... As shown in Fig. 1b, the direct sequencing of exon 7 of the GHR gene in the patient revealed peaks of both G and T at position 724 in contrast to only a single peak of G in the control. The G to T transversion changed codon 224 from GAG (Glu) to TAG (stop) (Fig. 2b). The direct sequencing of exon 10 ...
Chapter 9 Notes - schallesbiology
Chapter 9 Notes - schallesbiology

... • Collected numerical data- it was the ratios of the crosses that clinched the arguments for his theories • The chosen characters all showed dominant/recessive traits- this made his analysis much easier • He was lucky- some of his characters were on the same chromosome, but were so far apart that cr ...
evolution and mechanism of translation in chloroplasts
evolution and mechanism of translation in chloroplasts

... of the large IR (112). No such IR has been observed in cyanobacterial genomes analyzed so far. The genomes of Synechococcus 6301 (49) and of Synechocystis PCC 6803 (50) contain two copies of rRNA gene clusters in the inverse orientation, but no additional genes are present in the repeats. Therefore, ...
Human Sex Determination
Human Sex Determination

... in vitro. No such region has been identified in human SRY protein, suggesting that it may act as a repressor rather than an activator of transcription. Amongst primates, SRY sequences have evolved rapidly outside the HMG box, indicating that only this conserved motif has an important function (Ramki ...
Meiosis
Meiosis

... this point, the chromatids are very close to each other and  some material from two chromatids switch chromosomes,  that is, the material breaks off and reattaches at the same  position on the homologous chromosome.  This is like  cutting and pasting pieces of chromosomes.  As long as  the same area ...
Maize Metabolic Network Construction and Transcriptome Analysis
Maize Metabolic Network Construction and Transcriptome Analysis

... gene products, and metabolites that regulate the development of cellular components, cells, tissues, organs, and physiological manifestations of the biochemical networks in response to various extrinsic and intrinsic signals. Understanding maize metabolism at a systems level requires a multifaceted ...
gyrA AND SEQUENCING METHOD
gyrA AND SEQUENCING METHOD

... are point mutations in the gyrAgene and increased efflux contribution. In this study, all of the isolates resistant to nalidixic acid had a single mutation in gyrA. However, efflux pump activity could be less important in decreasing ciprofloxacin susceptibility levels, atleast the low level of resis ...
figures - HAL
figures - HAL

... the c.909C>G mutations were shown to lie in trans, after sequencing of the cloned products of the patient’s RAX exon 3 (Figure 2). ...
Mendelian Inheritance in Humans
Mendelian Inheritance in Humans

... X-linked allele is always expressed in males. Because females have two X chromosomes, they have two alleles for any X-linked trait. Therefore, they must inherit two copies of the recessive allele to express the recessive trait. This explains why X-linked recessive traits are less common in females t ...
Full-Text PDF
Full-Text PDF

... only the LTR region revealed 227 integrations with high homology (>80%, mostly >95%) assigned to 31/32 chromosomes, including the X chromosome (Figure 2), the Y chromosome could not be investigated. Only chromosome 24 did not contain any EqERV-beta1 LTR sequences. The largest number of hits (22) was ...
Fooyin University
Fooyin University

... Zi-Ling Jian1、Shu-Juan Lee1、Jeng-Chung Lo2、Yan-Ni Lee1、Lan-Xin Liu1、Su-May Yu3、Wen-Lii Huang1* of Biotechnology, Fooyin Univ., Kaohsiung Hsien、2Tainan Dist. Agri. Res. & Exten. Stat、3Instit. of Mol. Biol., Academic Sinica, ROC、 *E-mail: [email protected] ...
Letter The Evolution of Male–Female Sexual
Letter The Evolution of Male–Female Sexual

... be related to control of gamete size in colonial volvocine algae as predicted earlier by the gamete size regulator recruitment model for the evolution of anisogamy/oogamy from isogamous mating types (Charlesworth 1978). If this model applies to MAT3, then the degree of differentiation between MAT3 a ...
Contextual Genetic Algorithms: Evolving Developmental Rules
Contextual Genetic Algorithms: Evolving Developmental Rules

... If the concentrations of editing operators can be linked to environmental contexts, the concentrations of different proteins obtained may be selected accordingly, and thus evolve a system which is able to respond to environmental changes without changes in the major part of its genetic information ( ...
upstream sequence of a differentiation
upstream sequence of a differentiation

... 1986, 1989). Several other cultured rabbit cell types including esophageal epithelial cells, kidney epithelial cells, mesothelial cells and fibroblasts do not synthesize K3. Therefore a panel of cultured cells, all of the same rabbit origin, is available, and is ideally suited for studying the tissu ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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