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Nonstationary Functional Optimization
Nonstationary Functional Optimization

... Figure 1: A Representation of the Structured Genetic Algorithm. genes) do not disappear, they remain in the chromosome structure and are carried in a neutral and apparently redundant form to subsequent generations with the individual's string of genes . Since sGA is highly structured, a single chang ...
Qualitative Analysis of Regulatory Graphs: A Computational Tool
Qualitative Analysis of Regulatory Graphs: A Computational Tool

... with source gi such that l = sinf (T ); consequently, any non trivial expression level of gene gi corresponds to a threshold from which an interaction (with source gi ) becomes functional (thus for each gene, the maximum level equals at most the number of interactions exerted by this gene). Let Ij b ...
Gene Section JUN (V-Jun sarcoma virus 17 oncogene homolog (avian))
Gene Section JUN (V-Jun sarcoma virus 17 oncogene homolog (avian))

... apoptosis and transformation. JUN promotes cell cycle transition from G1 phase to S phase by up-regulating cyclin D1 expression and antagonizing the function of p53and p21. The JUN protein is involved in both the induction and prevention of apoptosis, possibly dependent on the types and development ...
Ch. 7: Presentation Slides
Ch. 7: Presentation Slides

... • Green-pigment genes may be present in multiple copies on the X-chromosome due to mispairing and unequal crossing-over • Unequal crossing-over between these genes during meiotic recombination can also result in gene deletion and colorblindness • Results in chimeric (composite) gene ...
GN Barley Tutorial
GN Barley Tutorial

... The upper part of the QTL Cluster otput is a hierarchical cluster tree of the set of traits that were selected in the previous window. To generate this plot, distances between pairs of traits using (1 - r) where r is the Pearson product-moment correlation were computed. The hierarchy is assembled by ...
FTv6_6_changes
FTv6_6_changes

... prepared by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB) (published in Enzyme Nomenclature 1992, Academic Press, San Diego, or a more recent revision thereof). The format represents a string of four numbers separated by full stops; up to thre ...
evodevo - eweb.furman.edu
evodevo - eweb.furman.edu

... III. Weak Linkage Regulation ...
Single-Molecule Experiments in Synthetic Biology: An
Single-Molecule Experiments in Synthetic Biology: An

... Norbert Sewald,* Robert Ros, and Dario Anselmetti* Gene expression in eukaryotes is controlled at the transcriptional level by the specific binding of transcription factors to defined DNA sequences. In this way, cell growth, differentiation, and development are regulated. The possibility to influenc ...
Human Traits Lab
Human Traits Lab

... widow’s peak straight hairline attached ear lobe ...
Revealing the genetic roots of obesity and type 2 diabetes
Revealing the genetic roots of obesity and type 2 diabetes

... could be replicated in a Dutch T2D cohort. Two common variants (rs7923837 and rs1111875) located near the HHEX gene were genotyped in 501 unrelated T2D patients and in 920 healthy controls. The major alleles of both variants were over-represented in T2D cases compared with controls (66.7% vs 64.1%, ...
Neutral theory 3: Rates and patterns of molecular evolution
Neutral theory 3: Rates and patterns of molecular evolution

Basic Horse Genetics - Alabama Cooperative Extension System
Basic Horse Genetics - Alabama Cooperative Extension System

... only one gene for any allele that he or she has to the offspring. For example, the base coat color of any horse may be either black with a genotype of EE or Ee or chestnut (sorrel) with a genotype of ee. The homozygous black horse (EE) can contribute only an E gene to the offspring. The homozygous c ...
Information. How to bring your samples
Information. How to bring your samples

... The High Capacity cDNA Reverse Transcription Kit (Applied Biosystems®) delivers extremely high-quality, single-stranded cDNA from 0.02 to 2 µg total RNA. Quantitative first-strand synthesis of all RNA species is achieved with the use of random primers. Downstream applications include real-time PCR, ...
Genetics - Mendelian Inheritance & Heredity Lecture PowerPoint
Genetics - Mendelian Inheritance & Heredity Lecture PowerPoint

... • The SPO Virtual Classrooms offer many educational resources, including practice test questions, review questions, lecture PowerPoints, video tutorials, sample assignments and course syllabi. New materials are continually being developed, so check back frequently, or follow us on Facebook (Science ...
Week 8
Week 8

... – Otherwise, they loose out to the others who do manage to maximize their growth rates in the same conditions and thus come to dominate the populations ...
RTPrimerDB: the real-time PCR primer and probe database, major
RTPrimerDB: the real-time PCR primer and probe database, major

... annotation data and links to Entrez Gene and Ensembl, followed by a graphical representation of the aligned primer and probe sequences onto the different transcript variants available from Ensembl. The occurrence of SNPs in the region where the primer/probe anneals and the exact location of the ampl ...
Characterization of the soil microbial community associated with the
Characterization of the soil microbial community associated with the

... lipase purified PCR product of known copy number. The standard curve was used to determine the copy number per gram of sediment. The qPCR measurements were performed in triplicate. The amplification efficiency (E) was calculated from the slope of the standard curve using the formula: percent E ¼ 10e1/s ...
Introduction_to_Human_Genetics
Introduction_to_Human_Genetics

... product necessary for a specific biological function If a mutation occurs in that allele, the function for which it encodes is also lost The degree to which the function is lost can vary ...
Manual
Manual

... An alpha significance threshold may be specified. This defaults to 0.05. We may zoom to a certain chromosome by specifying the chr parameter. For chr=0 the whole genome is displayed (default) In addition to specifying the chromosome, we may zoom to a specific region, starting at the start parameter ...
Genetics - sciencephs
Genetics - sciencephs

... Studied pea plants  Self-pollination and cross-pollination  Studies 1 trait at a time - Monohybrid  Studies short vs. tall plants over several generations, then also studies other plant traits separately ...
Nucleotide sequence of the genomic RNA of pepper mild mottle
Nucleotide sequence of the genomic RNA of pepper mild mottle

... The 126K and 183K proteins are thought to be involved in viral replication because they have been detected in partially purified preparations of the viral polymerase complex and because they contain several sequence motifs which are conserved in proteins known to act in replicative processes of plan ...
Genomic Screening for Artificial Selection during Domestication and
Genomic Screening for Artificial Selection during Domestication and

... candidate region was narrowed within about 1 kb by a mapbased cloning strategy. Seven fixed single nucleotide polymorphisms (SNPs) were identified between maize landraces and teosintes: one nonsynonymous substitution (i.e. amino acid substitution) and six SNPs in the 5’ side of the promoter region. ...
SUPPLEMENTARY INFORMATION TABLE OF CONTENTS: 1
SUPPLEMENTARY INFORMATION TABLE OF CONTENTS: 1

... the coding sequence of the degenerate TE (DIRE). This algorithm extends the boundaries of each ORF by 300 bp on both ends and a modified SmithWaterman alignment [147] is then performed between the proteins, including ...
DNA ppt notes 2015
DNA ppt notes 2015

... James Watson, Francis Crick, and Maurice Wilkins jointly received the Nobel Prize in 1962 for their determination of the structure of DNA. What is interesting about this fact is that Rosalind Franklin had as much to do with the discovery as the other three gentlemen with her work with X-ray crystall ...
CB3 - Homework
CB3 - Homework

... DNA consists of two helix-shaped backbones or ‘spines’ joined together by ‘rungs’. Each rung is made of substances called ‘bases’. Each rung contains two bases, which are joined together. We describe this as a ‘base pair’. You will need a copy of the second page of this sheet on a separate piece of ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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