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Replicators and Vehicles by Richard Dawkins he theory of natural
Replicators and Vehicles by Richard Dawkins he theory of natural

Heredity
Heredity

... gene. One allele codes for purple flowers; plants with the purple allele have purple flowers. Another allele codes for white flowers; white flowered plants have “white” alleles. Alleles occur in pairs in adult organisms; therefore, the flowering plants of our example might have two of the same allel ...
Complete Genome Sequence of Bacillus thuringiensis Strain 407 Cry-
Complete Genome Sequence of Bacillus thuringiensis Strain 407 Cry-

... a genetic model for studying virulence mechanisms and the pathways that contribute to pathogenicity (3–7). So far, the complete genome sequences of five B. thuringiensis strains have been reported (1, 8–11). Here, we report the complete genome sequence of B. thuringiensis strain 407 Cry-, which will ...
PcGs and Hox genes - Development
PcGs and Hox genes - Development

... three Hox genes, although the timing of misexpression differs for each Hox gene. High levels of Ubx misexpression are already apparent within 24 hours of clone induction (Fig. 2). Misexpression of Abd-B is also detectable within 24 hours of clone induction and accumulates to high levels by 48 hours ...
Complete genome sequence of the rifamycin SV
Complete genome sequence of the rifamycin SV

... 390 874 bp and 6 808 937–6 829 319 bp were recognized in the chromosome. Both of them were highly similar to pMEA100, which has been characterized in several species of Amycolatopsis [16]. The replication origin (oriC) of the chromosome is the same as that previously characterized [7], and in this s ...
Chromatin regulates origin activity in Drosophila follicle cells
Chromatin regulates origin activity in Drosophila follicle cells

... specificity occurs in Drosophila, where somatic follicle cells of the ovary transition from genomic replication to exclusive rereplication at origins that control amplification of the eggshell (chorion) protein genes2. Here we show that chromatin acetylation is critical for this developmental transi ...
Ends-out, or replacement, gene targeting in Drosophila
Ends-out, or replacement, gene targeting in Drosophila

... frequent as a result of excision and loss of y⫹. One possible explanation supposes that repair of the cut chromosomal ends is very inefficient, and although targeting may have occurred, those cells died because of a failure to fix the chromosomal DSB at the donor site. Alternatively, repair of a DSB ...
Pisum Genetics Volume 26 1994 Preface 1 PGA "Pisum Genetics
Pisum Genetics Volume 26 1994 Preface 1 PGA "Pisum Genetics

... Coordinator of Gene Symbols. If you are proposing a new gene symbol please check with Mike that the symbol is free and appropriate. In most cases not more than three letters are necessary to symbolise a locus. Again if you are proposing a new gene please make a reasonable effort to check for allelis ...
docx - Association for Biology Laboratory Education
docx - Association for Biology Laboratory Education

... Drosophila – Assume you are a geneticist. You have just returned from one of the more remote areas of the Hawaiian Islands. On the islands you collected specimens from different populations of fruit flies that were endemic (found only in this area). In this initial wild or fieldcaught population, th ...
Application of Bruchin B to pea pods results in
Application of Bruchin B to pea pods results in

... genome sequences revealed more than 600 P450 genes in ...
Lab 7: Molecular Biology
Lab 7: Molecular Biology

... scientific achievements. In the late 1800’s and early 1900’s, Gregor Mendel and his successors determined that heredity was controlled by discrete factors (that we now call genes). Early cell biologists found a strong correlation between the behavior of genes and the behavior of cellular structures ...
Genetics
Genetics

... formation of gametes (reproductive cells), pairs of allele for a specific trait separate so that offspring receive one factor from each parent. ...
Supplementary Information
Supplementary Information

... DNA and RNA fractions were isolated from the tissue using an AllPrep DNA/RNA mini kit (Qiagen) per the manufacturer’s procedure. Approximately 120 mg of frozen GBM tissue was lysed in a buffer containing guanidine-isothiocyanate to inactivate DNases and RNases and to ensure isolation of intact DNA a ...
Chapter 14 Study Guide Mendel and the Gene Idea A.P. Biology Ms
Chapter 14 Study Guide Mendel and the Gene Idea A.P. Biology Ms

... and IB alleles are said to be co-dominant. 22. Define and give examples of pleiotrophy and epistasis. 23. Describe a simple model for polygenic inheritance and explain why most polygenic characters are described in quantitative. 24. Describe how environmental conditions can influence the phenotypic ...
One amino acid makes the difference: the formation of ent
One amino acid makes the difference: the formation of ent

... Terpenoids are found in almost all life forms fulfilling a wide array of important functions. With over 60,000 different structures described at present, terpenoids represent the largest and structurally most diverse group of natural products [1]. This biodiversity arises from only a few prenyl diph ...
Leukaemia Section t(5;9)(q14.1;p24) SSBP2/JAK2 Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(5;9)(q14.1;p24) SSBP2/JAK2 Atlas of Genetics and Cytogenetics in Oncology and Haematology

... a). Partial GTG-banded karyotypes showing the t(5;9)(q14.1;p24.1). b). Partial FISH analysis showing the 5'JAK2 hybridization signal on der(5), the 3'JAK2 hybridization signal on der(9) and an intact JAK2 hybridization signal on the normal chromosome 9. ...
Warren, ST and Nelson, DL: Trinucleotide repeat expansions in neurological disease. Current Opinion in Neurobiology 3:752-759 (1993).
Warren, ST and Nelson, DL: Trinucleotide repeat expansions in neurological disease. Current Opinion in Neurobiology 3:752-759 (1993).

... genetic disease have followed rules and examples set forth in model systems such as Drosophila and yeast. In recent years, however, new mechanisms responsible for genetic disease have emerged where little or no precedent had been established in other genetically studied organisms. One such mechanism ...
Identification of several different lineages of measles virus
Identification of several different lineages of measles virus

... number of divergent sequences. The data show that the MV strains analysed so far fall into a number of more or less closely related groups. Group A consists of the laboratory-adapted Edmonston vaccine strains, including the Moraten and Schwarz vaccine-associated cases and the Hall6 strain of SSPE vi ...
Validating Genome-Wide Association Candidates
Validating Genome-Wide Association Candidates

... has made identifying its genetic basis an important goal for plant biologists (Oldroyd et al., 2011). More than 30 plant genes that play central roles in the formation and growth of plant nodules, the site of rhizobial symbiosis, and nitrogen fixation have been identified (Popp and Ott, 2011; Pislariu ...
Ku Binds Telomeric DNA in Vitro - Titia de Lange Lab
Ku Binds Telomeric DNA in Vitro - Titia de Lange Lab

... Ku Binds to Telomeric DNA Ends in Vitro—Given the DNAend binding activity of Ku and its suggested role at yeast telomeres, it was of interest to investigate the ability of Ku to bind to telomeric DNA in vitro. Oligonucleotides were synthesized terminating in the human telomeric TTAGGG repeats in dif ...
Somatotropic axis
Somatotropic axis

... Somatotropic axis ...
Lec-GenomeAllignment2010
Lec-GenomeAllignment2010

... Figure 1. The difference between positional homology alignment and glocal alignment. Three example linear genomes are broken into genes labeled A,B,C,D, and R. R is a multicopy (repetitive) gene, with different copies labeled using numeric subscripts. Each copy of R is assumed to be identical in se ...
Expansion of tandem repeats and oligomer
Expansion of tandem repeats and oligomer

... in the Section 3, can also be explained by the mutational rate variability and can be t by the model. 5. Cluster measures We quantify [38] the repetitions of oligomers by dividing the sequence into the non-overlapping windows of n nucleotides, where n is the size of an oligomer. For trimers (n = 3) ...
Spider Syndrome - OSU Fact Sheets
Spider Syndrome - OSU Fact Sheets

... to the sex of the individual; these are called sex linked. Other genes, such as eye color, hair color, etc., are not related to an individual’s sex. These are called autosomal genes. An autosomal genetic trait can, therefore, be found in both the male and female. ...
Mutations changes of genetic information
Mutations changes of genetic information

... is neither the beginning nor the end of the way ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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