Symposium Poster - uospur
... Abstract: Defects in the development and formation of synapses can cause neuronal and synaptic overgrowth, which can lead to many neurological disorders including autism. Previous studies have shown that defective FMR1 and ADAR genes result in synaptic overgrowth in Drosophila neuromuscular junction ...
... Abstract: Defects in the development and formation of synapses can cause neuronal and synaptic overgrowth, which can lead to many neurological disorders including autism. Previous studies have shown that defective FMR1 and ADAR genes result in synaptic overgrowth in Drosophila neuromuscular junction ...
PDF
... supplementary material). Finally, we analysed Insm1 expression in the hindbrain of Phox2b mutant mice, as Phox2b has been reported to be an essential regulator of Insm1 in the PNS (Wildner et al., 2008), and found that Insm1 expression persisted in these mice (data not shown). Together, these data ...
... supplementary material). Finally, we analysed Insm1 expression in the hindbrain of Phox2b mutant mice, as Phox2b has been reported to be an essential regulator of Insm1 in the PNS (Wildner et al., 2008), and found that Insm1 expression persisted in these mice (data not shown). Together, these data ...
Open access article
... population of M2 progeny of 4,904 ethyl methanesulfonate-mutagenized M1 embryos is available for single nucleotide polymorphism mutation detection, using a TILLING (for Targeting Induced Local Lesions IN Genomes) protocol. Scanning subsets of this population, we identified a mutation load of one per ...
... population of M2 progeny of 4,904 ethyl methanesulfonate-mutagenized M1 embryos is available for single nucleotide polymorphism mutation detection, using a TILLING (for Targeting Induced Local Lesions IN Genomes) protocol. Scanning subsets of this population, we identified a mutation load of one per ...
Xdbx inhibits neurogenesis - Development
... neural progenitor domains in the embryo? The homeodomaincontaining gene Xiro3 is expressed at highest levels in neural progenitors and when overexpressed, Xiro3 inhibits neuronal differentiation in the embryo (Bellefroid et al., 1998). The Xenopus zinc finger transcription factor gene Zic2 may also ...
... neural progenitor domains in the embryo? The homeodomaincontaining gene Xiro3 is expressed at highest levels in neural progenitors and when overexpressed, Xiro3 inhibits neuronal differentiation in the embryo (Bellefroid et al., 1998). The Xenopus zinc finger transcription factor gene Zic2 may also ...
Ch 14 summary - OHS General Biology
... 2. For each character, an organism inherits two copies of a gene, one from each parent. o A diploid organism inherits one set of chromosomes from each parent. o Each diploid organism has a pair of homologous chromosomes and, therefore, two copies of each gene. These are also called alleles of that g ...
... 2. For each character, an organism inherits two copies of a gene, one from each parent. o A diploid organism inherits one set of chromosomes from each parent. o Each diploid organism has a pair of homologous chromosomes and, therefore, two copies of each gene. These are also called alleles of that g ...
pdf
... originally studied by Mendel. In other cases, transposition can activate nearby genes by bringing an enhancer of transcription (within the transposable element) close enough to a gene to stimulate its expression. If the target gene is not usually expressed in a certain cell type, this activation can ...
... originally studied by Mendel. In other cases, transposition can activate nearby genes by bringing an enhancer of transcription (within the transposable element) close enough to a gene to stimulate its expression. If the target gene is not usually expressed in a certain cell type, this activation can ...
Genetics Notes
... were widely grown in Europe into the 17th Century. The Dutch growers developed them to be sweeter, more practical and more orange. Finally we have the French to thank for popular modern varieties, with credit to the 19th century horticulturist Louis de Vilmorin, who laid the foundations for modern p ...
... were widely grown in Europe into the 17th Century. The Dutch growers developed them to be sweeter, more practical and more orange. Finally we have the French to thank for popular modern varieties, with credit to the 19th century horticulturist Louis de Vilmorin, who laid the foundations for modern p ...
Obesity — a genetic disease of adipose tissue?
... environmental factors (mainly overeating and physical inactivity) play the most important role in the development of overweight, it is very likely that genetic factors also contribute. It appears that one major gene in combination with one or several minor genes constitute the genetic components beh ...
... environmental factors (mainly overeating and physical inactivity) play the most important role in the development of overweight, it is very likely that genetic factors also contribute. It appears that one major gene in combination with one or several minor genes constitute the genetic components beh ...
Module 8: Horizontal Gene Transfer
... show an ancestral lineage. An unrooted person's family tree would show clusters of blood relatives, but would not show who was ancestor or progeny in those clusters. The T-Coffee website that you have already used in the Sequence Based Similarity Module allows for the construction of basic cladogram ...
... show an ancestral lineage. An unrooted person's family tree would show clusters of blood relatives, but would not show who was ancestor or progeny in those clusters. The T-Coffee website that you have already used in the Sequence Based Similarity Module allows for the construction of basic cladogram ...
PDF - 1.9 MB
... Mutants that do not complement each other (progeny have mutant phenotype) are said to be in the same complementation group and therefore in the same gene. Based on noncomplementation of the recessive mutations, we can conclude that mutants 1 and 3 form one complementation group and are mutations in ...
... Mutants that do not complement each other (progeny have mutant phenotype) are said to be in the same complementation group and therefore in the same gene. Based on noncomplementation of the recessive mutations, we can conclude that mutants 1 and 3 form one complementation group and are mutations in ...
Analytical approaches to RNA profiling data for
... The mammalian brain is the most complex organ of the body, containing hundreds of intermingled cell populations. These cells can be classified into types according to their morphology, projections, functions and gene expression profiles. Currently, in vivo analysis of gene expression and translation ...
... The mammalian brain is the most complex organ of the body, containing hundreds of intermingled cell populations. These cells can be classified into types according to their morphology, projections, functions and gene expression profiles. Currently, in vivo analysis of gene expression and translation ...
-Chain Gene in Epididymis α Expression of the C4b
... normal murine epididymis at a significant level, but it decreased drastically after castration, suggesting that epididymal expression of the C4BP␣ gene is regulated by androgen. Gene analysis of guinea pig C4BP␣ indicated that liver and epididymis C4BP␣ mRNA share the coding region and 3ⴕ-untranslat ...
... normal murine epididymis at a significant level, but it decreased drastically after castration, suggesting that epididymal expression of the C4BP␣ gene is regulated by androgen. Gene analysis of guinea pig C4BP␣ indicated that liver and epididymis C4BP␣ mRNA share the coding region and 3ⴕ-untranslat ...
The Meaning of Sex: Genes and Gender Lecture Three—Sex and
... The little worm, C. elegans, has come up with its own solution. It, too, must have dosage compensation, and what it does is slightly different from the human. In the case of the nematode, once again, the two X chromosomes of the hermaphrodite and the one X chromosome of the male ultimately make the ...
... The little worm, C. elegans, has come up with its own solution. It, too, must have dosage compensation, and what it does is slightly different from the human. In the case of the nematode, once again, the two X chromosomes of the hermaphrodite and the one X chromosome of the male ultimately make the ...
Conserved syntenic clusters of protein coding genes are missing in
... putative missing genes in birds cluster into approximately 100 conserved syntenic blocks in lizard and humans. The approximately 1,000 remaining candidate missing genes occur as singletons throughout non-avian genomes, or are associated with segments that have not been included in the main avian ass ...
... putative missing genes in birds cluster into approximately 100 conserved syntenic blocks in lizard and humans. The approximately 1,000 remaining candidate missing genes occur as singletons throughout non-avian genomes, or are associated with segments that have not been included in the main avian ass ...
Mechanistic Models of Cancer in the Space of Pathways
... Each sample of a given tumor type had no more than six mutated CAN genes in common Sjoblom 2006 Mechanistic Models of Cancer Progression, Elena Edelman presenting ...
... Each sample of a given tumor type had no more than six mutated CAN genes in common Sjoblom 2006 Mechanistic Models of Cancer Progression, Elena Edelman presenting ...
ppt
... So there must be a dominant gene at both loci to produce color. Indeed, by mating two strains together, we can determine whether the mutation is the result of different alleles at the same locus, or different GENES acting on one PATHWAY. This is called a complementation test. ...
... So there must be a dominant gene at both loci to produce color. Indeed, by mating two strains together, we can determine whether the mutation is the result of different alleles at the same locus, or different GENES acting on one PATHWAY. This is called a complementation test. ...
A systematic screen for tube morphogenesis and branching genes in the Drosophila tracheal system. PLoS Genetics 7: e1002087.
... chemically-induced mutations for tracheal morphogenesis defects in embryos and larval tracheal and air sac primordium clones have been conducted [34,35,36] along with more targeted genetic and genomic screens for genes that are expressed or function downstream of some of the key early signaling path ...
... chemically-induced mutations for tracheal morphogenesis defects in embryos and larval tracheal and air sac primordium clones have been conducted [34,35,36] along with more targeted genetic and genomic screens for genes that are expressed or function downstream of some of the key early signaling path ...
A global picture of tRNA genes in plant genomes
... in plants, and is mostly correlated with genome size. The number of tRNA pseudogenes and organellar-like tRNA genes present in nuclear genomes varies greatly from one plant species to another. These pseudogenes or organellar-like genes appear to be generated or inserted randomly during evolution. In ...
... in plants, and is mostly correlated with genome size. The number of tRNA pseudogenes and organellar-like tRNA genes present in nuclear genomes varies greatly from one plant species to another. These pseudogenes or organellar-like genes appear to be generated or inserted randomly during evolution. In ...
Conserved syntenic clusters of protein coding genes are missing in birds
... putative missing genes in birds cluster into approximately 100 conserved syntenic blocks in lizard and humans. The approximately 1,000 remaining candidate missing genes occur as singletons throughout non-avian genomes, or are associated with segments that have not been included in the main avian ass ...
... putative missing genes in birds cluster into approximately 100 conserved syntenic blocks in lizard and humans. The approximately 1,000 remaining candidate missing genes occur as singletons throughout non-avian genomes, or are associated with segments that have not been included in the main avian ass ...
Targeted gene expression as a means of altering cell fates and
... 1. pUAST: we constructed a vector into which genes can be subcloned behind the GAL UAS. A fragment containing five optimized GAL4 binding sites (the ‘ScaI site’ 17-mer; Webster et al., 1988) and a synthetic TATA box (Lillie and Green, 1989) separated by a unique NotI site from the SV40 terminator wa ...
... 1. pUAST: we constructed a vector into which genes can be subcloned behind the GAL UAS. A fragment containing five optimized GAL4 binding sites (the ‘ScaI site’ 17-mer; Webster et al., 1988) and a synthetic TATA box (Lillie and Green, 1989) separated by a unique NotI site from the SV40 terminator wa ...