Feng Zhang, Ph.D.
... recognized for developing another breakthrough technology called optogenetics (Zhang et al., Nature Protocols 2010) with Karl Deisseroth at Stanford University and Edward Boyden, now of MIT. Nature Methods named optogenetics its 2010 Method of the Year. Zhang demonstrated the utility of optogenetics ...
... recognized for developing another breakthrough technology called optogenetics (Zhang et al., Nature Protocols 2010) with Karl Deisseroth at Stanford University and Edward Boyden, now of MIT. Nature Methods named optogenetics its 2010 Method of the Year. Zhang demonstrated the utility of optogenetics ...
Dragons are a curious type of creature. Amazingly
... ________________________________________________________________________________ b. For which traits is the puppy homozygous? __________________________________________ ________________________________________________________________________________ ...
... ________________________________________________________________________________ b. For which traits is the puppy homozygous? __________________________________________ ________________________________________________________________________________ ...
Chapter 10
... • More than two alleles can exist for any specific gene, but only two of them will be found within any individual. • We use letters to denote alleles, since every gene has two alleles, all genes can be represented by a pair of letters. ...
... • More than two alleles can exist for any specific gene, but only two of them will be found within any individual. • We use letters to denote alleles, since every gene has two alleles, all genes can be represented by a pair of letters. ...
Project2Report
... Validation is a very important step of any such clustering algorithm. It helps rank clustering results, so that we will know the quality and reliability of the clustering results. I can even help determine the right parameters to some clustering algorithm. In this project, we chose Random Index and ...
... Validation is a very important step of any such clustering algorithm. It helps rank clustering results, so that we will know the quality and reliability of the clustering results. I can even help determine the right parameters to some clustering algorithm. In this project, we chose Random Index and ...
Sex-linked dosage-sensitive modifiers as imprinting
... (1988) have described a number of modifying genes that affect white-mottled and yellow variegation. Their extensive genetic analyses define two classes of modifiers. Those in class I are deficiency-dependent suppressors and duplication-dependent enhancers of variegation. (A suppressor of variegation ...
... (1988) have described a number of modifying genes that affect white-mottled and yellow variegation. Their extensive genetic analyses define two classes of modifiers. Those in class I are deficiency-dependent suppressors and duplication-dependent enhancers of variegation. (A suppressor of variegation ...
Cluster analysis for microaray data
... K-means clustering • Input: N objects given as data points in Rp • Specify the number k of clusters. • Initialize k cluster centers. Iterate until convergence: - Assign each object to the cluster with the closest center ...
... K-means clustering • Input: N objects given as data points in Rp • Specify the number k of clusters. • Initialize k cluster centers. Iterate until convergence: - Assign each object to the cluster with the closest center ...
Cluster analysis for microaray data
... K-means clustering • Input: N objects given as data points in Rp • Specify the number k of clusters. • Initialize k cluster centers. Iterate until convergence: - Assign each object to the cluster with the closest center ...
... K-means clustering • Input: N objects given as data points in Rp • Specify the number k of clusters. • Initialize k cluster centers. Iterate until convergence: - Assign each object to the cluster with the closest center ...
Welcome to Comp 665 - UNC Computational Genetics
... segments organized into structures called chromosomes • Chromosomes vary between different organisms. The DNA molecule may be circular or linear, and can contain from 10,000 to 1,000,000,000 nucleotides. • Simple single-cell organisms (prokaryotes, cells without nuclei such as bacteria) generally ha ...
... segments organized into structures called chromosomes • Chromosomes vary between different organisms. The DNA molecule may be circular or linear, and can contain from 10,000 to 1,000,000,000 nucleotides. • Simple single-cell organisms (prokaryotes, cells without nuclei such as bacteria) generally ha ...
Pepper Mapping & Major Genes - Department of Plant Sciences
... chromosomes indicates that the cl mutation is not caused by these genes • Although CL was mapped in pepper and the genes encoding for the catabolism enzymes were mapped in tomato, the comparative pepper-tomato map indicates that these chromosomal regions are syntenic between the 2 species • The loca ...
... chromosomes indicates that the cl mutation is not caused by these genes • Although CL was mapped in pepper and the genes encoding for the catabolism enzymes were mapped in tomato, the comparative pepper-tomato map indicates that these chromosomal regions are syntenic between the 2 species • The loca ...
Slide 1 - Faculty Web Pages
... 5.) Determine whether heterozygous parent was in cis or in trans for all three alleles on his/her non-recombinant chromosomes (the most frequent progeny class represents the non-recombinant chromosome configuration) 6.) Determine gene order based on DCOs and non-recombinant chromosome of het parent ...
... 5.) Determine whether heterozygous parent was in cis or in trans for all three alleles on his/her non-recombinant chromosomes (the most frequent progeny class represents the non-recombinant chromosome configuration) 6.) Determine gene order based on DCOs and non-recombinant chromosome of het parent ...
open access - Max-Planck-Institut für Pflanzenzüchtungsforschung
... a novelty, only to be used for food there in the 17th or 18th century. Tomato cultivars were subsequently reintroduced to the Americas. Thus, cultivated tomato has undergone a series of sequential bottlenecks, resulting in extremely low intraspecific genetic diversity (15). The most obvious domestica ...
... a novelty, only to be used for food there in the 17th or 18th century. Tomato cultivars were subsequently reintroduced to the Americas. Thus, cultivated tomato has undergone a series of sequential bottlenecks, resulting in extremely low intraspecific genetic diversity (15). The most obvious domestica ...
The function of chromatin modifiers in lineage commitment and cell
... or gene expression changes upon loss of a given protein, in very few cases has this easily translated into an understanding of how the function of that protein actually influences a developmental process. Given that many chromatin modifying proteins will largely exert their influence through control ...
... or gene expression changes upon loss of a given protein, in very few cases has this easily translated into an understanding of how the function of that protein actually influences a developmental process. Given that many chromatin modifying proteins will largely exert their influence through control ...
MTHFr, Methylation and Metals
... In females methylation is used regularly to solve a problem. Men have only one X chromosome and women have two. As a result, female cells might be expected to make twice as much protein from the information on X chromosomes as males do. Instead, women's cells randomly pick one of the X chromosomes a ...
... In females methylation is used regularly to solve a problem. Men have only one X chromosome and women have two. As a result, female cells might be expected to make twice as much protein from the information on X chromosomes as males do. Instead, women's cells randomly pick one of the X chromosomes a ...
Slide 1
... next three levels - molecules, cells and organisms - is understood very poorly. However, the two upper levels - of populations and of ecosystems, are simpler again, and there are many useful partial theories of their Macroevolution. ...
... next three levels - molecules, cells and organisms - is understood very poorly. However, the two upper levels - of populations and of ecosystems, are simpler again, and there are many useful partial theories of their Macroevolution. ...
Understanding the Genetics of HHT
... DNA (deoxyrebonucleic acid) is a molecule found in almost every cell of our body. It carries the instructions (sometimes referred to as “blueprints”) for the formation of all parts of our body during development, as well as for the substances our body needs in order to work and maintain itself over ...
... DNA (deoxyrebonucleic acid) is a molecule found in almost every cell of our body. It carries the instructions (sometimes referred to as “blueprints”) for the formation of all parts of our body during development, as well as for the substances our body needs in order to work and maintain itself over ...
Expression and Characterization of PRRSV ORF5a
... important disease of swine worldwide. Recent investigations in both PRRSV and equine arteritis virus have identified a previously unknown viral protein produced from the subgenomic mRNA5, designated ORF5a protein. In PRRSV, this protein consists of 51 amino acids, and possesses a conserved RQ-rich d ...
... important disease of swine worldwide. Recent investigations in both PRRSV and equine arteritis virus have identified a previously unknown viral protein produced from the subgenomic mRNA5, designated ORF5a protein. In PRRSV, this protein consists of 51 amino acids, and possesses a conserved RQ-rich d ...
genotype–phenotype correlation difficult. As far as we know, this is
... not reveal additional genomic variation. Furthermore, mutation screening of the TRPS1 also did not reveal any alteration. Finally, expression studies of TRPS1 performed from LCLs indicate that inter-individual variation is higher than the expected gene expression changes induced by the translocation ...
... not reveal additional genomic variation. Furthermore, mutation screening of the TRPS1 also did not reveal any alteration. Finally, expression studies of TRPS1 performed from LCLs indicate that inter-individual variation is higher than the expected gene expression changes induced by the translocation ...
Document
... Mendel then crossed these second generation tall pea plants and ended up with 1 out 4 being small. x ...
... Mendel then crossed these second generation tall pea plants and ended up with 1 out 4 being small. x ...
shortridge
... 2. Will levy’s brother substitute for levy to rescue paralysis in the mutant? Construct hybrid genes and transfer back into mutant lines. 3. What are the expression profiles of levy and levy’s brother? Are they tissue-specific like in humans? RT-PCR, Northerns, epitope tags, transformants expressing ...
... 2. Will levy’s brother substitute for levy to rescue paralysis in the mutant? Construct hybrid genes and transfer back into mutant lines. 3. What are the expression profiles of levy and levy’s brother? Are they tissue-specific like in humans? RT-PCR, Northerns, epitope tags, transformants expressing ...
Molecular Classification of Cancer: Class Discovery and Class
... • The choice to use 50 informative genes in the predictor was somewhat arbitrary: well within the total number of genes strongly correlated with the class distinction; seemed large enough to be robust against noise, and small enough to be readily applied in a clinical setting. ...
... • The choice to use 50 informative genes in the predictor was somewhat arbitrary: well within the total number of genes strongly correlated with the class distinction; seemed large enough to be robust against noise, and small enough to be readily applied in a clinical setting. ...