Copy number variations involving the microtubule
... models and more recently in mouse models, it has also been shown that tau reduction affects axonal elongation and neuronal migration [26]. This would be consistent with the phenotypes of hypotonia and mental retardation observed in most patients. However, as tau is essentially expressed in neurons, ...
... models and more recently in mouse models, it has also been shown that tau reduction affects axonal elongation and neuronal migration [26]. This would be consistent with the phenotypes of hypotonia and mental retardation observed in most patients. However, as tau is essentially expressed in neurons, ...
Archives of Microbiology
... signiWcance. In a neighbor-joining analysis of all available deduced VnfDG sequences, those from cyanobacteria clustered next to those from Methanosarcina spp. and were clearly separated from AnfDAnfG (Fig. 2). The close similarity of the cyanobacterial vnfDG to vnfDvnfG of Methanosarcina spp. might ...
... signiWcance. In a neighbor-joining analysis of all available deduced VnfDG sequences, those from cyanobacteria clustered next to those from Methanosarcina spp. and were clearly separated from AnfDAnfG (Fig. 2). The close similarity of the cyanobacterial vnfDG to vnfDvnfG of Methanosarcina spp. might ...
Biology
... Griffith called this process transformation because one strain of bacteria (the harmless strain) had changed permanently into another (the diseasecausing strain). Griffith hypothesized that a factor must contain information that could change harmless bacteria ...
... Griffith called this process transformation because one strain of bacteria (the harmless strain) had changed permanently into another (the diseasecausing strain). Griffith hypothesized that a factor must contain information that could change harmless bacteria ...
13024_2016_132_MOESM1_ESM
... c: In situ hybridization of progranulin mRNA in the DRGs ipsi- and contralateral of a sciatic nerve injury in STOPGrnflfl and Nestin-Grn-OE mice. Scale bars: 50 µm. d: Immunofluorescence analyses of the ipsilateral sciatic nerves 1d, 3d and 7d after crush injury of the sciatic nerve in STOP-Grnflfl ...
... c: In situ hybridization of progranulin mRNA in the DRGs ipsi- and contralateral of a sciatic nerve injury in STOPGrnflfl and Nestin-Grn-OE mice. Scale bars: 50 µm. d: Immunofluorescence analyses of the ipsilateral sciatic nerves 1d, 3d and 7d after crush injury of the sciatic nerve in STOP-Grnflfl ...
Characterisation of marsupial PHLDA2 reveals eutherian specific acquisition of imprinting Open Access
... Background: Genomic imprinting causes parent-of-origin specific gene expression by differential epigenetic modifications between two parental genomes. We previously reported that there is no evidence of genomic imprinting of CDKN1C in the KCNQ1 domain in the placenta of an Australian marsupial, the ...
... Background: Genomic imprinting causes parent-of-origin specific gene expression by differential epigenetic modifications between two parental genomes. We previously reported that there is no evidence of genomic imprinting of CDKN1C in the KCNQ1 domain in the placenta of an Australian marsupial, the ...
Genome position and gene amplification | SpringerLink
... may also be distinguished by their propensity to amplify oncogenes, suggesting that the particular types of genomic instability present in a tumor are important determinants of how expression of an oncogene might be altered. Moreover, amplification is often associated with poor prognosis. Amplificat ...
... may also be distinguished by their propensity to amplify oncogenes, suggesting that the particular types of genomic instability present in a tumor are important determinants of how expression of an oncogene might be altered. Moreover, amplification is often associated with poor prognosis. Amplificat ...
We need an optimality criterion to choose a best estimate (tree
... Therefore, scientists use algorithms that explore the tree space without examining every possible tree. These methods are not guaranteed to find the best phylogenetic estimate(s) for the data, but they often do. ...
... Therefore, scientists use algorithms that explore the tree space without examining every possible tree. These methods are not guaranteed to find the best phylogenetic estimate(s) for the data, but they often do. ...
Argonaute2 Is Essential for Mammalian
... and in the epiblast cells near the primitive streak [17,18]. To determine whether a proper primitive streak is formed in the Ago2 mutants, we examined the expression of T in Ago2 null embryos by whole-mount in situ hybridization. We found that ...
... and in the epiblast cells near the primitive streak [17,18]. To determine whether a proper primitive streak is formed in the Ago2 mutants, we examined the expression of T in Ago2 null embryos by whole-mount in situ hybridization. We found that ...
Variants in the 1q21 risk region are associated with a visual
... but they have sometimes been overlooked in favor of cognitive and neurophysiological endophenotypes, for which neural substrates are often unknown. Here, we report a genome-wide association study of a basic visual endophenotype associated with psychological disorder. Sensitivity to frequency-doubled ...
... but they have sometimes been overlooked in favor of cognitive and neurophysiological endophenotypes, for which neural substrates are often unknown. Here, we report a genome-wide association study of a basic visual endophenotype associated with psychological disorder. Sensitivity to frequency-doubled ...
Quantitative Inheritance - NAU jan.ucc.nau.edu web server
... • Work by Edward East (1916) on inheritance of corolla height in longflower tobacco, and theoretical work by R.A. Fisher reconciled the Mendelians and the biometricians by showing that quantitative inheritance could be explained on the assumption of Mendelian genetics, and with the additional assump ...
... • Work by Edward East (1916) on inheritance of corolla height in longflower tobacco, and theoretical work by R.A. Fisher reconciled the Mendelians and the biometricians by showing that quantitative inheritance could be explained on the assumption of Mendelian genetics, and with the additional assump ...
Ensembl Genome Browser - molecularevolution.org
... Expressed Sequence Tags (ESTs) cDNAs or mRNAs from related species Expression array probe set mapping ...
... Expressed Sequence Tags (ESTs) cDNAs or mRNAs from related species Expression array probe set mapping ...
gene (Pun1? - UC Davis Plant Sciences
... – epistatic to all other pungency-related genes – Qualitative effect on presence/absence of capsaicinoids – Is it a master regulator of the pathway? – Mapped to chromosome 2 – cDNA from SSH library co-segregated with pungency in C.chinense – CAP marker has been used in breeding programs ...
... – epistatic to all other pungency-related genes – Qualitative effect on presence/absence of capsaicinoids – Is it a master regulator of the pathway? – Mapped to chromosome 2 – cDNA from SSH library co-segregated with pungency in C.chinense – CAP marker has been used in breeding programs ...
HiPer® Bacterial Conjugation Teaching Kit
... as F+) donate their DNA and other “female types” (designated as F-) receive the DNA as shown in Figure 1. Fcells become F+ when they acquire a small amount of DNA. Hence the F factor is called as the Fertility factor. In contemporary microbiology, the donor’s F factors are known to be plasmids which ...
... as F+) donate their DNA and other “female types” (designated as F-) receive the DNA as shown in Figure 1. Fcells become F+ when they acquire a small amount of DNA. Hence the F factor is called as the Fertility factor. In contemporary microbiology, the donor’s F factors are known to be plasmids which ...
Cloning and Sequencing of a Gene from Bacillus
... The degree of homology of the DNA from different species of Bacillus has previously been studied by both interspecific transformation and DNA hybridization (Seki et al., 1975, 1979). Interspecific transformation, however, is known to be extremely inefficient (te Riele & Venema, 1982a). There is evid ...
... The degree of homology of the DNA from different species of Bacillus has previously been studied by both interspecific transformation and DNA hybridization (Seki et al., 1975, 1979). Interspecific transformation, however, is known to be extremely inefficient (te Riele & Venema, 1982a). There is evid ...
Genomic and Proteomic Analysis of Mitochondrial Carrier Proteins
... Plant mitochondria maintain metabolic communication with the cytosol through a family of carrier proteins. In Arabidopsis, a subset of 45 putative genes encoding members of this family have been identified based on generalized mitochondrial carrier features. No gene clusters are apparent and few of ...
... Plant mitochondria maintain metabolic communication with the cytosol through a family of carrier proteins. In Arabidopsis, a subset of 45 putative genes encoding members of this family have been identified based on generalized mitochondrial carrier features. No gene clusters are apparent and few of ...
array CGH - Unique The Rare Chromosome Disorder Support Group
... find out what those genes do? With an array CGH test is often possible to determine how many and which genes are missing or duplicated. At present we only understand the role of a small minority of genes and their association with particular clinical features. However, where a gene’s association wit ...
... find out what those genes do? With an array CGH test is often possible to determine how many and which genes are missing or duplicated. At present we only understand the role of a small minority of genes and their association with particular clinical features. However, where a gene’s association wit ...
Microarrays
... 0.1 ng gDNA and 104 cfu/mL in a pure culture. Even though the authors reported reliable detection from binary and ternary mixtures, data on the relative sensitivity of the microarray have not been provided. Analysis of mock spiked PIF samples revealed sensitivity in the range of 1–10 cfu/25 g sample ...
... 0.1 ng gDNA and 104 cfu/mL in a pure culture. Even though the authors reported reliable detection from binary and ternary mixtures, data on the relative sensitivity of the microarray have not been provided. Analysis of mock spiked PIF samples revealed sensitivity in the range of 1–10 cfu/25 g sample ...
MAGMA manual (version 1.03)
... annotation in the .genes.annot file. This can be useful when using one of the SNP location files on the MAGMA site, since these contain all SNPs in the corresponding dbSNP release, and will otherwise produce very large .genes.annot files. It can also be used to restrict a subsequent gene analysis to ...
... annotation in the .genes.annot file. This can be useful when using one of the SNP location files on the MAGMA site, since these contain all SNPs in the corresponding dbSNP release, and will otherwise produce very large .genes.annot files. It can also be used to restrict a subsequent gene analysis to ...
Package `TCGAbiolinks`
... query <- GDCquery(project = "TCGA-COAD", data.category = "Clinical", barcode = c("TCGA-RU-A8FL","TCGA-AA-3972")) GDCdownload(query) clinical <- GDCprepare_clinic(query,"patient") clinical.drug <- GDCprepare_clinic(query,"drug") clinical.radiation <- GDCprepare_clinic(query,"radiation") clinical.admi ...
... query <- GDCquery(project = "TCGA-COAD", data.category = "Clinical", barcode = c("TCGA-RU-A8FL","TCGA-AA-3972")) GDCdownload(query) clinical <- GDCprepare_clinic(query,"patient") clinical.drug <- GDCprepare_clinic(query,"drug") clinical.radiation <- GDCprepare_clinic(query,"radiation") clinical.admi ...
The Caenorhabditis elegans NK-2 class
... hlh-1, expressed specifically in body wall muscles and their clonal precursors (Krause et al., 1990). No hlh-1 expression is seen in pharyngeal muscle or the minor muscles, suggesting that differentiation of these muscle types may be analogous to that of vertebrate cardiac or smooth muscle. We have ...
... hlh-1, expressed specifically in body wall muscles and their clonal precursors (Krause et al., 1990). No hlh-1 expression is seen in pharyngeal muscle or the minor muscles, suggesting that differentiation of these muscle types may be analogous to that of vertebrate cardiac or smooth muscle. We have ...
Combining Microarrays and Biological Knowledge for
... candidate networks obtained in Step3. In Step2, we use the greedy hill-climbing algorithm for learning networks. The details are shown in Imoto et al. [23]. Note that the proposed prior probability of the network can be used for other types of Bayesian network models, such as discrete Bayesian netwo ...
... candidate networks obtained in Step3. In Step2, we use the greedy hill-climbing algorithm for learning networks. The details are shown in Imoto et al. [23]. Note that the proposed prior probability of the network can be used for other types of Bayesian network models, such as discrete Bayesian netwo ...
Oogenesis: Making the Mos of Meiosis
... GVBD and ovulation in early-stage (pre-MI) Clytia oocytes. These cnidarian c-mos genes are therefore capable of the same biological activities as vertebrate c-mos. Morpholino-mediated knockdown of the two CheMos genes demonstrates that, in Clytia, the roles of the two orthologues may not be identica ...
... GVBD and ovulation in early-stage (pre-MI) Clytia oocytes. These cnidarian c-mos genes are therefore capable of the same biological activities as vertebrate c-mos. Morpholino-mediated knockdown of the two CheMos genes demonstrates that, in Clytia, the roles of the two orthologues may not be identica ...
Prof. Kamakaka`s Lecture 1 Notes (PDF)
... Mendel returned to Brno and began his experiments with the hybrid cultivation of pea plants in 1856. After spending eight years carrying out experimental work in the monastery garden, he reported on the results of his observations at the meetings of the Association for Natural Research in Brno on th ...
... Mendel returned to Brno and began his experiments with the hybrid cultivation of pea plants in 1856. After spending eight years carrying out experimental work in the monastery garden, he reported on the results of his observations at the meetings of the Association for Natural Research in Brno on th ...
A Study of Gene Linkage and Mapping Using Tetrad Analysis
... separate but become part of a “pool” of meiotic products (gametes). The mating activities of the parents combine these meiotic products in a random fashion to produce the next generation. Thus, in most organisms, it is impossible to examine the assortment of alleles in an individual meiotic division ...
... separate but become part of a “pool” of meiotic products (gametes). The mating activities of the parents combine these meiotic products in a random fashion to produce the next generation. Thus, in most organisms, it is impossible to examine the assortment of alleles in an individual meiotic division ...