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Widespread ocular use oftopical chloramphenicol: is there justifiable
Widespread ocular use oftopical chloramphenicol: is there justifiable

... published, the incidence of chloramphenicol induced aplastic anaemia was reported as 1 in 24 500 to 40 800 with the incidence of chloramphenicol induced aplastic anaemia (from systemic use) being 13 times that of the idiopathic form (22 500 deaths of all causes were screened over an 18 month period ...
Asthma in children - Neonatal and Paediatric Pharmacists Group
Asthma in children - Neonatal and Paediatric Pharmacists Group

... agonist via a spacer device is as effective as nebulised • Children(and adults) with mild and moderate exacerbation of asthma should be treated by bronchodilator given from a pMDI + spacer with doses titrated according to clinical response ...
National Alliance for Drug Endangered Children Webinar Florida
National Alliance for Drug Endangered Children Webinar Florida

... present in the body for only an instant before they are degraded. In general they have a stabilizing, calming effect on the body, but there is a dark side. Cannabinoids present in the body for too long a time or in too high a concentration have deleterious effects. Effects of THC on development and ...
Guidelines on Clinical Management of Dengue Fever / Dengue
Guidelines on Clinical Management of Dengue Fever / Dengue

... extent of the country so that it has become a major public health issue. Incidence of severe forms of the disease, namely Dengue Haemorrhagic Fever and Dengue Shock Syndrome is also on the rise leading to increase in mortality. Sri Lanka experienced the largest outbreak of Dengue Fever in 2004 with ...
Seborrheic Dermatitis, Psoriasis, Recalcitrant Palmoplantar Eruptions, Pustular Dermatitis, and
Seborrheic Dermatitis, Psoriasis, Recalcitrant Palmoplantar Eruptions, Pustular Dermatitis, and

... arthritis, acute pustular psoriasis, more than 20% total body surface involvement, localized pustular psoriasis, psoriasis that affects certain areas of the body so that normal function and employment are prevented, lack of response to phototherapy, PUVA, or retinoids ...
Acute stridor in children - Oxford Academic
Acute stridor in children - Oxford Academic

... bronchoscopy or tracheostomy becomes necessary. Anaesthesia will normally be induced in the sitting position and i.v. cannulation is only attempted once the child is sufficiently obtunded. At laryngoscopy, the epiglottis will be red and swollen and the arytenoids and other supraglottic tissues infla ...
Anomalies of the Upper Urinary Tract
Anomalies of the Upper Urinary Tract

... When the mature kidney fails to reach its normal location in the “renal” fossa, the condition is known as renal ectopia. An ectopic kidney can be found in one of the following positions: pelvic, iliac, abdominal and contralateral. 50% percent of ectopic kidneys have hydronephrotic collecting system ...
Does quinine reduce leg cramps for young athletes?
Does quinine reduce leg cramps for young athletes?

... It should be noted that during the 2 weeks immediately following the treatment period, num- ...
Rota virus - WordPress.com
Rota virus - WordPress.com

... • If untreated, children can die from the resulting severe dehydration. • Depending on the severity of diarrhoea, treatment consists of oral rehydration, during which the child is given extra water to drink that contains small amounts of salt and sugar. • In 2004, the WHO and UNICEF recommended the ...
20 most frequently asked questions about colon cancer
20 most frequently asked questions about colon cancer

... 100 percent of these patients will get colorectal cancer, usually by their late 30s. The disease is inherited directly from an affected parent (autosomal dominant inheritance), which means that each child has a 50 percent or one in two chance of inheriting the abnormal gene. If the gene is inherited ...


... differentiating the cause of FUO. A rash occurs in up to 94% of children with S-JCA9 13-14 but may not be present or characteristic on initial evaluation. Typically it is erythematous, fine and mascular. It is evanescent, usually appearing at the height of the fever and it is therefore essential to ...
Management of Acetaminophen Toxicity
Management of Acetaminophen Toxicity

... may ensue. Timely administration of NAC may protect the patient from hepatic damage. Therapy should be initiated as soon as possible, but NAC is beneficial at any time. If APAP levels can not be obtained, assume a toxic dose has been ingested, ...
Epidemiology And Control of Acute Diarrheal Diseases
Epidemiology And Control of Acute Diarrheal Diseases

... Associate Professor Department of Community Medicine and Public Health ...
Function
Function

... Function: Carbohydrate metabolism, protein metabolism, the nervous system, the catalyst in the formation of gastric juice. Vitamin B1 is necessary for normal functioning of every cell in the body, especially to nerve cells. It stimulates the brain, necessary for the cardiovascular and endocrine syst ...
Antacids and cimetidine treatment for gastro
Antacids and cimetidine treatment for gastro

... respiratory-present in 18% of the patients. Pulmonary complications, considered a common finding in these children, may occur without vomiting or regurgitation and are a frequent indication for surgery in patients in whom medical treatment has failed.2 24 Sixteen patients showed a weight below the f ...
ceftriaxone associated acute gallbladder enlargement
ceftriaxone associated acute gallbladder enlargement

... group of patients significantly more often than in those who receive it for other reasons (68.6% vs 11.5%). Because of that, Meng postulates that ceftriaxone should be avoided in patients treated for hepatitis and biliary tract infections [1]. There are many reports of studies considering ceftriaxon ...
Association between Plaque-Type Psoriasis and Perianal
Association between Plaque-Type Psoriasis and Perianal

... swabs as well as urine analysis to monitor for poststreptococcal glomerulonephritis. To the best of our knowledge, combination of psoriasis and PSD has not been previously described in the literature, and whether it is merely a chance occurrence or an actual association remains to be seen. ...
CAH
CAH

... Paired box gene 8 - PAX8 - a member of the paired box (PAX) family • This gene encoded a transcription factor protein. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. • Mutations in this gene have been associated with thyroid dysgene ...
Rabies
Rabies

... even if they appear friendly. "Love your own, leave other animals alone" is a good principle for children to learn. • Prevent bats from entering living quarters or occupied spaces in homes, churches, schools, and other similar areas, where they might come in contact with people and pets. ...
Babesia Species
Babesia Species

... Babesia is the most frequently reported transfusion-transmitted infectious agent in the US. The CDC summarized 162 US cases of transfusion-associated babesiosis diagnosed from 1979 to 2009 primarily from blood centers in the Northeast US. Among the 162 US transfusion-associated cases, 159 were attri ...
Self-Assessment Examination - American College of Radiology
Self-Assessment Examination - American College of Radiology

... Langerhans cell histiocytosis (LCH) is a rare disease of uncertain etiology, likely a disorder of the immune system. The hallmark of LCH is the presence of the Langerhans cell, a histiocyte containing Birbeck granules that are demonstrable by electron microscopy. LCH of bone often presents with pain ...
Herpes Virus Infection - treatment guide for children and adoles- cents
Herpes Virus Infection - treatment guide for children and adoles- cents

... Apply with a cotton-tipped applicator to avoid spread to other body sites. ...
Congenital Adrenal Hyperplasia
Congenital Adrenal Hyperplasia

... hypotension, hyponatremia and hyperkalemia or later in childhood with early pubic hair & phallic enlargement accompanied by accelerated linear growth and advancement of skeletal maturation. High blood pressure & hypokalemia may occur in those with 11-b-hydroxylase deficiency and 17-ahydroxylase def ...
COTM0814 - California Tumor Tissue Registry
COTM0814 - California Tumor Tissue Registry

... concretions, or it may be extensive and occupy a large portion of the neoplasm. The subset with extensive calcification occurs mainly in the lower extremity and is slowly-growing. Most synovial sarcomas show immunoreactivity for epithelial markers (CK and EMA), TLE1, CD99, BCL-2 and calponin. In add ...
PHM 456 Common Infectious Diseases of Childhood, Part II
PHM 456 Common Infectious Diseases of Childhood, Part II

...  Outcomes: bacterial cultures, serology & PCR, ADRs, compliance and symptoms  As effective, fewer ADRs & good compliance ...
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Acute lymphoblastic leukemia



Acute lymphoblastic leukemia, also known as acute lymphocytic leukemia or acute lymphoid leukemia (ALL), is an acute form of leukemia, or cancer of the white blood cells, characterized by the overproduction and accumulation of cancerous, immature white blood cells, known as lymphoblasts. In persons with ALL, lymphoblasts are overproduced in the bone marrow and continuously multiply, causing damage and death by inhibiting the production of normal cells (such as red and white blood cells and platelets) in the bone marrow and by spreading (infiltrating) to other organs. ALL is most common in childhood, with a peak incidence at 2–5 years of age and another peak in old age.The symptoms of ALL are indicative of a reduced production of functional blood cells, because leukemia wastes the resources of the bone marrow that are normally used to produce new, functioning blood cells. These symptoms can include fever, increased risk of infection (especially bacterial infections like pneumonia, due to neutropenia; symptoms of such an infection include shortness of breath, chest pain, cough, vomiting, changes in bowel or bladder habits), increased tendency to bleed (due to thrombocytopenia), and signs indicative of anemia, including pallor, tachycardia (high heart rate), fatigue, and headache.About 6,000 cases are reported in the United States every year. Internationally, ALL is more common in Caucasians than in Africa; it is more common in Hispanics and in Latin America. Cure is a realistic goal and is achieved in more than 80% of affected children, although only 20-40% of adults are cured. ""Acute"" refers to the relatively short time course of the disease, distinguishing it from chronic lymphocytic leukemia, which has a potential time course of many years.ALL was one of the first cancers for which an effective chemotherapeutic treatment was developed. Antifolates like aminopterin and methotrexate were developed in the late 1940s by Sidney Farber and Yellapragada Subbarow. At that time, a doctor did not need a patient's or parent's consent to try an experimental treatment as the Nuremberg code had not yet been signed. Farber initially tried folic acid supplementation as a treatment for ALL. This had disastrous consequences and he likely accelerated the children's deaths.
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