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Slides
Slides

... species, leaving two copies in all descendants. ...
Welcome to the Broad Institute
Welcome to the Broad Institute

... data and analyze it in GenePattern directly • Detailed descriptions of the analyses, how to run them, and ...
A new type of heredity described in Paramecia
A new type of heredity described in Paramecia

Molecular Evolution - Faculty Web Sites at the University of Virginia
Molecular Evolution - Faculty Web Sites at the University of Virginia

... Genomes are continually evolving. Six classes of eukaryotic DNA sequences are commonly recognized, based on the number of copies of each Raven and Johnson 1999 ...
4- Random change student
4- Random change student

... The Hardy-Weinberg principle shows that if a certain set of conditions are met, the gene pool remains unchanged generation after generation. By showing what needs to happen to keep the gene pool unchanged, the principle also outlines what has to happen to change the gene pool. When the gene pool cha ...
RUNX1-RUNX1T1 pre
RUNX1-RUNX1T1 pre

... AND FLANKING INTRONS ...
Evolution of genomes
Evolution of genomes

... than what could be achieved by recombination alone. Most modifications in the course of evolution are due to copying errors in the process of DNA replication called mutations. These copying errors provide the raw material that natural selection acts on. Deleterious mutations tend to be eliminated by ...
Introduction to Genetics using Punnett Squares
Introduction to Genetics using Punnett Squares

... Punnett Squares ...
The 43 strains contain deletions that extend from the immunity
The 43 strains contain deletions that extend from the immunity

... C). (3 Points). Why were more prototrophs observed from the second culture? What is the molecular mechanism for the result? The culture that was grown at 30o C the entire time was repressed so there was little expression of int and xis to catalyze excision of the prophage which would make the cell T ...
Model Organisms pre-class activity: Huntington disease
Model Organisms pre-class activity: Huntington disease

... The number of repeats is related to the age of onset of Huntington disease. The greater the number of repeats the earlier the onset of the disease. 3. How does an excess number of repeats affect the protein created by this gene? ...
No Slide Title
No Slide Title

... Linkage occurs when two genes are near each other on the same chromosome. Their ‘linkage distance’ can be determined by seeing how frequently they segregate together. Consider two linked genes in a heterozygous individual: A ...
Chapter 10 answers
Chapter 10 answers

... SRY is the sex determining region of the Y chromosome. The SRY gene codes for a protein involved in primary sex determination – type of gamete produced and organs needed to produce them. The SRY gene must be present for testes and sperm to form. ...
Gene mutations and their effects
Gene mutations and their effects

... • Chemicals – there are hundreds of chemical mutagens, which act in different ways. Some change one base into another, e.g. nitrous acid changes cytosine into uracil. Since this pairs with adenine, the effect is to change a C–G pair into an A–T pair. Substances such as 5-bromouracil and 2-amino ...
Heredity
Heredity

...  Have the same inherited traits  Are the same sex (because they develop from identical embryos) ...
Human development and bechavior
Human development and bechavior

... Ffrom the father, whereas the female receives an X from each parent. The two little girls each had an XX combination. • Within the chromosomes are even more fundamental determiners of heredity, called genes, which contain the basic blueprint that specifically directs the development of most physical ...
Genetics and Hereditary PPT
Genetics and Hereditary PPT

... from mom, and one from dad- your body must decide which one to “express” or show.  The “stronger” of the two alleles will be the one that is expressed. This is called a dominant gene.  The allele that is not expressed, and is essentially hidden inside someone, is called the recessive gene. ...
Chapter 11: Gene Expression PPT
Chapter 11: Gene Expression PPT

... • The development of cells with specialized functions is called cell differentiation. • The development of form in an organism is called morphogenesis. • Both cell differentiation and morphogenesis are governed by gene expression. ...
9.5 Genomics and Bioinformatics
9.5 Genomics and Bioinformatics

... • Genomics is the study of genomes. – can include the sequencing of the genome – comparisons of genomes within and across species ...
9.5 Genomics and Bioinformatics KEY CONCEPT Entire genomes are sequenced, studied, and compared.
9.5 Genomics and Bioinformatics KEY CONCEPT Entire genomes are sequenced, studied, and compared.

... and entire genomes. • Genomics is the study of genomes. – can include the sequencing of the genome – comparisons of genomes within and across species ...
An Exception to Independent Assortment: Linked Genes
An Exception to Independent Assortment: Linked Genes

... 2. Morgan proposed that these unusual ratios were due to _______________ i.e. the gene for body color and wing size is located on the same chromosome. Example: In Fruit flies, grey body is dominant to black body and long wings are dominant to vestigial wings (a small, crinkled-up wing.) Cross a hete ...
Transgenic Animal Models
Transgenic Animal Models

... (5) Cells will divide in culture and some of them will incorporate the transgenic DNA strand into the chromosome (homologous recombination). After a sufficient number of cell divisions, add the antibiotic. This will preferentially kill those stem cells that have not incorporated the transgenic stra ...
Lecture#7 - Eukaryote gene structure and regulation.
Lecture#7 - Eukaryote gene structure and regulation.

... sequences Types of sequences 1) Single copy genes - includes most protein coding genes 2) Multiple copy genes - e.g. rRNA, tRNA, some protein coding genes. 3) Repeated sequences. 3a Short centromeric - tandem array - clustered 3b SINES Short INterspersed ElementS (Alu element – lab #9) 3c LINES Long ...
Sandra L. Batista  Education:     
Sandra L. Batista  Education:     

... Performed sample mapping, database management including dbGaP submission, genotyping, and imputation for a large scale  human genetics study that includes both genotype and expression data. Conducted gene co­expression network analysis on  the study data and other data sets using the Weighted Gene C ...
1-y-gender-genes
1-y-gender-genes

... differences in behaviour are biologically based – nature. However, if behaviour is found to be different across cultures, we may conclude that these behaviours are nurtured by the environment. Mead’s (1935) evidence has been used to support the idea of the environment being the main force in gender ...
Classical Genetics - Web Lesson
Classical Genetics - Web Lesson

... b) Do the problem set. Explain why it was important for Mendel to control certain factors in his experiment. ...
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Gene expression programming

In computer programming, gene expression programming (GEP) is an evolutionary algorithm that creates computer programs or models. These computer programs are complex tree structures that learn and adapt by changing their sizes, shapes, and composition, much like a living organism. And like living organisms, the computer programs of GEP are also encoded in simple linear chromosomes of fixed length. Thus, GEP is a genotype-phenotype system, benefiting from a simple genome to keep and transmit the genetic information and a complex phenotype to explore the environment and adapt to it.
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