CLASS 1 Introduction to genetics Dr. Szymon Zmorzyński A) TOPICS
... II) Basic terms: genetics, nucleic acid, DNA and RNA, DNA replication, DNA polymerase, helicase, DNA ligase, gene, allele (dominant and recessive), codominant alleles, exon, intron, transcription, reverse transcription, RNA polymerase, promotor, enhancer, silencer, translation, genetic code, codon, ...
... II) Basic terms: genetics, nucleic acid, DNA and RNA, DNA replication, DNA polymerase, helicase, DNA ligase, gene, allele (dominant and recessive), codominant alleles, exon, intron, transcription, reverse transcription, RNA polymerase, promotor, enhancer, silencer, translation, genetic code, codon, ...
ASCO_2008_files/Rothenberg Discussant Tailored Tx in PC ASCo
... Addition of EGFR Inhibitors to Gemcitabine + Bevacizumab in Advanced Pancreatic Cancer What Did They Do and Why is it Important? • Tried to build upon exciting early clinical data for gemcitabine + VEGF inhibitor (bevacizumab) and gemcitabine + EGFR inhibitor (erlotinib or cetuximab) • Promising pr ...
... Addition of EGFR Inhibitors to Gemcitabine + Bevacizumab in Advanced Pancreatic Cancer What Did They Do and Why is it Important? • Tried to build upon exciting early clinical data for gemcitabine + VEGF inhibitor (bevacizumab) and gemcitabine + EGFR inhibitor (erlotinib or cetuximab) • Promising pr ...
Mitosis and Meiosis
... The Y chromosome does not carry all of the genes of an X chromosome Females have two X chromosomes, so they carry two copies of each gene found on the X chromosome. This makes a backup gene available if one becomes damaged. Males have only one copy of each gene on their one X chromosome. The gene ...
... The Y chromosome does not carry all of the genes of an X chromosome Females have two X chromosomes, so they carry two copies of each gene found on the X chromosome. This makes a backup gene available if one becomes damaged. Males have only one copy of each gene on their one X chromosome. The gene ...
Chapter 10 Test - Mendelian Genetics
... 31. Black fur is dominant to gray fur in squirrels. What letter should be used to represent the recessive allele? a. B c. G b. b d. g 32. Genetic information is passed on to offspring during sexual reproduction by combining half the ...
... 31. Black fur is dominant to gray fur in squirrels. What letter should be used to represent the recessive allele? a. B c. G b. b d. g 32. Genetic information is passed on to offspring during sexual reproduction by combining half the ...
Gregor Mendel - HCC Learning Web
... The distribution of one pair of genes does not influence the distribution of other pairs of genes So....the presence tongue rolling will not affect the presence of tongue folding ...
... The distribution of one pair of genes does not influence the distribution of other pairs of genes So....the presence tongue rolling will not affect the presence of tongue folding ...
Student Packet 18 Laws of Segregation and Independent
... Move the mutation rate slider to 1.0. 2. Count: Move the Sim. speed slider all the way to the left. Click Play. A. After the parents mate, click Pause. How many offspring are there? ____ B. Click Play. After the birds eat, click Pause. How many offspring are left? ____ In nature, as in the Gizmo, ...
... Move the mutation rate slider to 1.0. 2. Count: Move the Sim. speed slider all the way to the left. Click Play. A. After the parents mate, click Pause. How many offspring are there? ____ B. Click Play. After the birds eat, click Pause. How many offspring are left? ____ In nature, as in the Gizmo, ...
THE SELFISH GENE
... Culture distinguishes individuals from the other living beings. Cultural transmission is a phenomenon similar to genetic transmission because it can provoke a sort of evolution. For example, changes in clothing, customs and feeding represent forms of progress. Taken that genes are replicators, a new ...
... Culture distinguishes individuals from the other living beings. Cultural transmission is a phenomenon similar to genetic transmission because it can provoke a sort of evolution. For example, changes in clothing, customs and feeding represent forms of progress. Taken that genes are replicators, a new ...
Supplementary methods
... pair identity. This mRNA encodes the PSG4 (pregnancy specific beta-1-glycoprotein 4) gene that is annotated as containing two immunoglobulin C-2 type regions, thus the reduced base pair identity is most likely due to haplotype differences. The RefSeq mRNA for this locus, NM_002780, aligns at nearly ...
... pair identity. This mRNA encodes the PSG4 (pregnancy specific beta-1-glycoprotein 4) gene that is annotated as containing two immunoglobulin C-2 type regions, thus the reduced base pair identity is most likely due to haplotype differences. The RefSeq mRNA for this locus, NM_002780, aligns at nearly ...
3_platform
... Clone annotation – either locally or linked to FLEXGene E-mail or web-based complaint system with record keeping A published and accessible list of their products, services, prices, expected response times and guaranteed delivery times • A completed MTA from each customer • Feedback on aberrant clon ...
... Clone annotation – either locally or linked to FLEXGene E-mail or web-based complaint system with record keeping A published and accessible list of their products, services, prices, expected response times and guaranteed delivery times • A completed MTA from each customer • Feedback on aberrant clon ...
Promoter identification
... binding sites for transcriptional activators and repressors ensuring that the gene is only transcribed in the proper cell type(s) and at the proper time during the development. ...
... binding sites for transcriptional activators and repressors ensuring that the gene is only transcribed in the proper cell type(s) and at the proper time during the development. ...
Chromosomal theory of inheritance
... • H0: based on Mendel’s first law of equal segregation the observed progeny fits a 1:1 ratio of girls : boys. • Chi-square = 2.76, df= 1, p>0.05, rejection level is p=0.05 • Therefore we conclude that for Χ2 =2.76, df=1 we would expect a deviation from the 1:1 ratio at least this large would occur b ...
... • H0: based on Mendel’s first law of equal segregation the observed progeny fits a 1:1 ratio of girls : boys. • Chi-square = 2.76, df= 1, p>0.05, rejection level is p=0.05 • Therefore we conclude that for Χ2 =2.76, df=1 we would expect a deviation from the 1:1 ratio at least this large would occur b ...
Sex-linked single-gene inheritance patterns
... Problem: What is the probability of getting 6(Red) 6(Green) 6(Blue) when all three dice are rolled at the same time? Each dice has six sides and the probability of obtaining any one side is 1/6. So the combined probability in the present example is 1/6 x 1/6 x ...
... Problem: What is the probability of getting 6(Red) 6(Green) 6(Blue) when all three dice are rolled at the same time? Each dice has six sides and the probability of obtaining any one side is 1/6. So the combined probability in the present example is 1/6 x 1/6 x ...
The Significance of the Fossil Record
... that interbreeds freely. The sum of all the alleles of all the members of the population is its gene pool. For each gene, every individual has only two alleles, but there may be more than two alleles in the gene pool, each with its own frequency. Evolution is frequently defined genetically as a chan ...
... that interbreeds freely. The sum of all the alleles of all the members of the population is its gene pool. For each gene, every individual has only two alleles, but there may be more than two alleles in the gene pool, each with its own frequency. Evolution is frequently defined genetically as a chan ...
epigenetika III
... sexual populations have a more rapid rate of evolution than would an otherwise equivalent group of asexual organisms. Fisher's conclusion depends on the rate of mutation: • If favorable mutations are rare, each one will have been fixed in the population before the next one arises. New favorable muta ...
... sexual populations have a more rapid rate of evolution than would an otherwise equivalent group of asexual organisms. Fisher's conclusion depends on the rate of mutation: • If favorable mutations are rare, each one will have been fixed in the population before the next one arises. New favorable muta ...
PPT - Bioinformatics.ca
... Annotations are contributed by many groups More than one annotation term allowed per gene Some genomes are annotated more than others Annotation comes from manual and electronic sources GO can be simplified for certain uses (GO Slim) ...
... Annotations are contributed by many groups More than one annotation term allowed per gene Some genomes are annotated more than others Annotation comes from manual and electronic sources GO can be simplified for certain uses (GO Slim) ...
Neurulation: Making the Brain and Spinal Cord
... The A-P axis of all animals appears to be specified by the expression of Hox genes that were first discovered in Drosophila. These genes are highly conserved between animals. These genes are highly organized on chromosomes and appear to be expressed sequentially in the same order that they are arran ...
... The A-P axis of all animals appears to be specified by the expression of Hox genes that were first discovered in Drosophila. These genes are highly conserved between animals. These genes are highly organized on chromosomes and appear to be expressed sequentially in the same order that they are arran ...
PATTERNS OF INHERITANCE
... The results of a cross are due to the experiment and not due to an inherent instability. b. This characteristic allows the experimenter to decide the parents of a cross. c. The offspring of each type can easily be counted. d. This characteristic will give a large number of offspring within a short t ...
... The results of a cross are due to the experiment and not due to an inherent instability. b. This characteristic allows the experimenter to decide the parents of a cross. c. The offspring of each type can easily be counted. d. This characteristic will give a large number of offspring within a short t ...
File - Groby Bio Page
... 3. Using a punnett square work out what the offspring of the F1 generation could be (All heterozygous Nn) 4. Look at what the phenotypes are in the F1 generation (All normal) 5. Second cross of offspring 6. Using a punnett square work out what the offspring of the F2 generation could be 7. Look at w ...
... 3. Using a punnett square work out what the offspring of the F1 generation could be (All heterozygous Nn) 4. Look at what the phenotypes are in the F1 generation (All normal) 5. Second cross of offspring 6. Using a punnett square work out what the offspring of the F2 generation could be 7. Look at w ...
Genotypes-phenotype predictions in patients diagnosed with
... Specifically, SNPs are annotated based on the genomic position, the genomic function (exonic, intronic, UTR, etc) and the effect on the exon (synonymous, nonsynonymous, stopgain, stoploss) (Table S1). Furthermore, nonsynonymous SNPs are annotated based on the effect of altering protein function. For ...
... Specifically, SNPs are annotated based on the genomic position, the genomic function (exonic, intronic, UTR, etc) and the effect on the exon (synonymous, nonsynonymous, stopgain, stoploss) (Table S1). Furthermore, nonsynonymous SNPs are annotated based on the effect of altering protein function. For ...
Creation of a Computational Pipeline to Extract Genes from
... pipeline consists of a Perl script that uses the chromosome number and start/stop locations of a specific QTL as command line arguments to extract gene information found within that particular QTL. In addition, the user can also provide a text file that contains multiple QTLs to be analyzed. Once th ...
... pipeline consists of a Perl script that uses the chromosome number and start/stop locations of a specific QTL as command line arguments to extract gene information found within that particular QTL. In addition, the user can also provide a text file that contains multiple QTLs to be analyzed. Once th ...
Gene Section MYST4 (MYST histone acetyltransferase (monocytic leukemia) 4)
... (see below) 5' MYST4 - CREBBP 3' (previously known as MORF-CBP, MORF- CREBBP, or MYST4CBP) fusion was first described in a 4-year-old girl with AML M5a without signs of erythrophagocytosis and several chromosome abnormalities. It was also described in an 84-year-old male without erythrophagocytosis ...
... (see below) 5' MYST4 - CREBBP 3' (previously known as MORF-CBP, MORF- CREBBP, or MYST4CBP) fusion was first described in a 4-year-old girl with AML M5a without signs of erythrophagocytosis and several chromosome abnormalities. It was also described in an 84-year-old male without erythrophagocytosis ...
Evolutionary deterioration of the vomeronasal pheromone
... that the genome of the higher primate ancestor had 140 functional V1R genes as in the mouse genome, we ask whether it is possible to have five V1R ORFs left in the present-day human genome simply by chance, without the presence of any functional constraints on them. By using computer simulation, we ...
... that the genome of the higher primate ancestor had 140 functional V1R genes as in the mouse genome, we ask whether it is possible to have five V1R ORFs left in the present-day human genome simply by chance, without the presence of any functional constraints on them. By using computer simulation, we ...
Organism # of Gamete # of Zygote # of Pairs of Zygote
... II. In Holstein cattle solid color is dominant over spotted coat. Ifa homoz\iygous solid colored bull is mated to a spotted cow for 12 breeding seasons, what would be the nature ofthe expected offspring, both phenotypically and genotypically? What results would be expected if both bull and cow were ...
... II. In Holstein cattle solid color is dominant over spotted coat. Ifa homoz\iygous solid colored bull is mated to a spotted cow for 12 breeding seasons, what would be the nature ofthe expected offspring, both phenotypically and genotypically? What results would be expected if both bull and cow were ...
Evolution of colour vision
... blue-yellow(B-Y): output from the S cones, comparing it to L + M cone responses red-green(R-G): output from the L cones, comparing it to M cone responses only blue-yellow system draws from S cones, S cones differ from M and L in physiology and retinal distribution B-Y more vulnerable: toxic expo ...
... blue-yellow(B-Y): output from the S cones, comparing it to L + M cone responses red-green(R-G): output from the L cones, comparing it to M cone responses only blue-yellow system draws from S cones, S cones differ from M and L in physiology and retinal distribution B-Y more vulnerable: toxic expo ...