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The agouti mouse model: an epigenetic
The agouti mouse model: an epigenetic

... epigenetic inheritance, although their exact roles remain to be elucidated. When developmental biologist Conrad Waddington first envisioned the epigenetic landscape as a metaphor for cellular determination during development, it is doubtful he could have predicted the full complexity of the field 50 y ...
Minds may be computers but.. - Cognitive Science Department
Minds may be computers but.. - Cognitive Science Department

... One of those strategies is break the job of trying to understand our minds into parts and allocate each part to different groups of people. We let one group (neurologists) focus on how the mind is implemented by the brain. We let another group (psychologists) look at the behavior that things with mi ...
Genetic consequences of directional selection in
Genetic consequences of directional selection in

... 1.1  Genetic adaptation to local conditions requires evolution by natural selection ...................................................................................... 15  1.2  Evolution by random processes and natural selection............................. 15  1.3  Genetic architecture of adapta ...
Adaptationism and the adaptive landscape - Peter Godfrey
Adaptationism and the adaptive landscape - Peter Godfrey

... evolved in a different context and for a different purpose. Critics also point to the importance of mechanistic factors. In many cases, the underlying genetic or developmental mechanisms may place inherent limitations on the degree to which an organism can adapt.1 The debates over adaptationism are ...
Neural Networks
Neural Networks

... • Proof is not constructive (does not tell how construct  MNN) • Even if constructive, would be of no use, we do not know the  desired function, our goal is to learn it through the samples • But this result gives confidence that we are on the right track  • MNN is general (expressive) enough to cons ...
Applications of Genome Rearrangements
Applications of Genome Rearrangements

... compute the minimum number of inversions, translocations, fusions or fissions necessary to transform a multichromosomal genome into another. Sketch of the approach: ...
University of Birmingham Immunolabelling of human metaphase
University of Birmingham Immunolabelling of human metaphase

... ten original spreads are shown in Additional file 1). Banding is consistent between sister chromatids, (particularly visible on chromosomes 1, 6, 9, 11 and 12), and from one homologue pair to another (Figure 2). It is noteworthy that the overall pattern of immunofluorescent bands is maintained even ...
A possible association between panic disorder
A possible association between panic disorder

Possible consequences of the overlap between the CaMV 35S
Possible consequences of the overlap between the CaMV 35S

... based on the phenotype of the transgenic plant and bioinformatic analyses. In case characteristics attributed to the expression of the P6 gene are observed it should be analyzed if the ORF is expressed. In conclusion, different P35S variants are in use to express proteins in transgenic plants. Here, ...
The Genetic Structure and Evolutionary Fate of Parthenogenetic
The Genetic Structure and Evolutionary Fate of Parthenogenetic

... Goldblatt, 1967). Finally, we assume that generations of reproduction do not overlap and that population size remains constant. Mutation: Figure 3 is a schematic representation of genetic change in the triploid populations caused by mutation alone. This model assumes that P (the probability of quadr ...
The Genetic Theory of Natural Selection
The Genetic Theory of Natural Selection

... can get lost, because the few individuals who carry it happen to not survive or reproduce. Therefore, if we want to understand the role of natural selection in real populations, we need to factor in population size. Remember that the probability of fixation for any neutrally evolving allele A is giv ...
here - Genetics
here - Genetics

... unique nucleotide sequence for the locus in question, and thus constitutes the designation of an allele. In bacterial genetics, the practice of using a plus (+) sign to indicate the wildtype allele of a locus has been borrowed from the genetic nomenclature system used for other organisms. Thus, araB ...
Regionalization in the mammalian telencephalon - Fishell Lab
Regionalization in the mammalian telencephalon - Fishell Lab

... adhesion systems have been shown to be protected from proteases when calcium is present (491). This is relevant because calcium-specific adhesion systems distinguish between the dorsal versus the ventral telencephalon early but not later in development [45”]. Together, these findings suggest that ca ...
Algorithm selection by rational metareasoning as
Algorithm selection by rational metareasoning as

... model-free reinforcement learning [18–20]. The REinforcement Learning among Cognitive Strategies model (RELACS [19]) and the Strategy Selection Learning model (SSL [20]) each postulate that people learn just one number for each cognitive strategy: the expected reward of applying it to an unknown pro ...
The importance of having two X chromosomes - Neuroscience
The importance of having two X chromosomes - Neuroscience

... The X chromosome is one of the most unusual chromosomes in mammals, because it is present in different numbers in males and females. There are numerous ramifications of this inherent imbalance. The inequality in genomic dose of X genes is thought to present a major problem [3], but perhaps for only ...
Molecular pathogenesis of feline leukemia virus
Molecular pathogenesis of feline leukemia virus

... adjacent genes. Moreover, some reports have also showed chromosomal aberrations in cats with hematopoietic and lymphoid malignancies (Grindem and Buoen, 1989; Gulino, 1992; Wu et al., 1995; Mayr et al., 1996; Fujino et al., 2004). The analyses of chromosomal FeLV insertions and abnormalities in feli ...
IOSR Journal of Agriculture and Veterinary Science (IOSR-JAVS)
IOSR Journal of Agriculture and Veterinary Science (IOSR-JAVS)

... plates until the pure cultures were obtained [8]. Isolates were found to be motile and flagellated, Gram negative, rod shaped positive for indole, catalase, oxidase tests, produced gas from glucose but did not hydrolyze esculin. Upon detailed bacteriological investigation, 56(77.78%) isolates were t ...
Unit 4, Lesson 10 Chromosomes and Genetics
Unit 4, Lesson 10 Chromosomes and Genetics

... Ladies and gentlemen, do our chromosomes change over time? What causes them to change? A change in the structure of the chromosome is a genetic mutation. There are three ways chromosomes are generally mutated. All result in the organism to lose the ability to function normally. An example of a mutat ...
Meiosis I
Meiosis I

... Daughter cells have half the number of chromosomes as first cell Results in four genetically different haploid cells ...
A multispecies approach for comparing sequence evolution of X
A multispecies approach for comparing sequence evolution of X

... Population genetics models show that, under certain conditions, the X chromosome is expected to be under more efficient selection than the autosomes. This could lead to ‘faster-X evolution ’, if a large proportion of mutations are fixed by positive selection, as suggested by recent studies in Drosop ...
Does RAGE protect smokers from COPD? CORRESPONDENCE
Does RAGE protect smokers from COPD? CORRESPONDENCE

OrthoMaM: a database of orthologous genomic markers for
OrthoMaM: a database of orthologous genomic markers for

... (Orthologous Mammalian Markers) database can be queried and alignments can be downloaded through a dedicated web interface http://kimura.univ-montp2.fr/orthomam. Conclusion: The importance of marker choice in phylogenetic studies has long been stressed. Our database centered on complete genome infor ...
Analysis of flower pigmentation mutants generated by random
Analysis of flower pigmentation mutants generated by random

... novel host (reviewed by Kunze et al., 1997; Osborne and Baker, 1995). We undertook the original approach and characterized the endogenous transposons of Petunia hybrida to exploit them for gene-tagging. In P. hybrida eight unstable alleles, typical for transposon insertions, had been described for s ...
Marfan syndrome
Marfan syndrome

... “Marfan database” has been developed that includes not only molecular but also clinical data. ...
Powerpoint
Powerpoint

... The queue of group comparisons still waiting for calculation. The process of calculating a single group comparison takes 20 sec to 5 minutes, depending on the number and type of arrays. ...
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Gene expression programming

In computer programming, gene expression programming (GEP) is an evolutionary algorithm that creates computer programs or models. These computer programs are complex tree structures that learn and adapt by changing their sizes, shapes, and composition, much like a living organism. And like living organisms, the computer programs of GEP are also encoded in simple linear chromosomes of fixed length. Thus, GEP is a genotype-phenotype system, benefiting from a simple genome to keep and transmit the genetic information and a complex phenotype to explore the environment and adapt to it.
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