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Evolution of Steroid Receptors
Evolution of Steroid Receptors

... for the ancestral CR and extant MRs are underlined; cortisol, the ligand for the tetrapod GR, is overlined. The terminal addition of aldosterone is in green. Asterisks, steps catalyzed by the cytochrome P-450 11bhydroxylase enzyme; only the tetrapod enzyme can catalyze the step marked with a green a ...
Detection of mcr-1 colistin resistance gene in
Detection of mcr-1 colistin resistance gene in

... [14]. Given the discrepancies between the international committees and the lack of colistin breakpoints for Enterobacteriaceae in CLSI, we considered it convenient to apply a screening method. Although disc diffusion is not recommended to test colistin susceptibility, it was useful for an initial sc ...
final_report_columns
final_report_columns

... eventually predict the disease potential of an identified variant (more information on: http://www.mutationtaster.org/info/documentation.html). According to: http://annovar.openbioinformatics.org/en/latest/user-guide/filter/#-mutationtaster-annotation: there are four possible predictions: "A" ("dise ...
Epigenetic chromatin states uniquely define the developmental
Epigenetic chromatin states uniquely define the developmental

... process that arises from a small pool of self-renewing hematopoietic stem cells (HSCs). Upon induction of differentiation, HSCs lose self-renewal ability and develop through a series of specialized progenitor cell types that possess restricted differentiation potential.1 Although several cell-intrin ...
03-Biological 42-3-Rosa
03-Biological 42-3-Rosa

... malabaricus (Oyakawa, 2003). Although a small family, Erythrinids are taxonomically controversial, including several species lacking a precise identification. Among these species, Hoplias malabaricus, commonly known as “traíra” ...
Microarray-based comparative genomic hybridisation (array CGH)
Microarray-based comparative genomic hybridisation (array CGH)

... (where a section of a chromosome is inverted or reversed), will not be identified using array CGH. This is because balanced chromosome rearrangements do not result in any loss or gain of chromosome material. It will also not detect some types of polyploidy (more than the usual 2 sets of chromosomes) ...
Sager JJ, Bai Q, Burton EA
Sager JJ, Bai Q, Burton EA

... development. Because developmental brain abnormalities are recognized as an important feature of childhood neurological disorders such as epilepsy and autism, we determined whether zebrafish mutants with grossly abnormal brain structure exhibit spontaneous electrical activity that resembles the long ...
Genes in conflict: the biology of selfish genetic elements
Genes in conflict: the biology of selfish genetic elements

... by a linear hierarchy of alleles at the nuclear matA locus, with the “losing” mtDNA being actively degraded soon after gamete fusion (Kawano and Kuroiwa 1989, Meland et al. 1991). And, in many plant species mtDNA is either stripped from mitochondria or severely degraded during pollen maturation, pri ...
Text S1 Snitkin and Segrè, Epistatic interaction maps relative to
Text S1 Snitkin and Segrè, Epistatic interaction maps relative to

... rely on any assumptions as to how the phenotypic effects of independent mutations should combine. We felt that such a metric would be ideal for the current multi there is no evidence that the effects of mutations should phenotype analysis, where combine in the same way for all phenotypes. We avoid ...
Concept of DNA and RNA
Concept of DNA and RNA

... composed of DNA (or RNA) inside a protein coat/shell called a capsid. It was also known that viruses replicate by taking over the host cell metabolic functions to make more virus. We are used to thinking and talking about viruses, which invade our bodies and make us sick, but there are other, differ ...
What Makes the “Blue” in Blueberries?
What Makes the “Blue” in Blueberries?

... Laboratory Methods in Genomics Spring 2011 ...
identifying patterns - paint horse association of new zealand
identifying patterns - paint horse association of new zealand

... "Typical" markings are at least one white sock, (in the majority of cases) back socks usually end in an upward shaped point, white on bottom lip (not always) coon tail (not always) white ticking in coat, particularly in flank area. Small blaze too bald or apron faced. "Louder" examples will have whi ...
secondary school improvement programme - Sci
secondary school improvement programme - Sci

... clear understanding of the genetic terminology in order to study genetics and answer genetic problems. Mendel’s Laws are very important - understand the concepts of dominance and how this plays a role in monohybrid crosses (mono = one = one characteristic or trait). Be aware of confusing the word ‘c ...
The Spectrum and Frequency of Self
The Spectrum and Frequency of Self

... with a mutant phenotype from several Ac donor lines and found only 24 such Ac inactivation events. The system that we report on here is highly efficient for isolating these more rare events, which most likely arise from DSB repair by an error-prone DNA synthesis pathway and from aberrant transpositio ...
The sequence of a gene encoding convicilin from pea
The sequence of a gene encoding convicilin from pea

... pea seeds, in addition to legumin and vicilin [1]. It can be purified from both legumin and vicilin, and it consists solely of polypeptides of Mr approx. 71 000. It does not thus contain polypeptides found in either of the two major storage proteins [2]. On the other hand, convicilin is antigenicall ...
THE DNA OF CAENORHABDITIS ELEGANS HE small
THE DNA OF CAENORHABDITIS ELEGANS HE small

... component corresponds to 0.67 x lo8 base pairs, which leads to an estimate of 0.8 x lo8 base pairs for the haploid genome of C. elegans. This is in good agreement with the haploid DNA content measured chemically, and reinforces the conclusion that the slow component is uniquely represented in the ge ...
Consanguinity and genetic disorders
Consanguinity and genetic disorders

... when these families inquire about risks of recurrence in future children. This study shows that only autosomal recessive conditions were strongly associated with ...
The Functional Organization of the Vestigial Locus in Drosophila
The Functional Organization of the Vestigial Locus in Drosophila

... WILLIAMS, ATKIN, AND BELL, MOLECULAR AND GENERAL GENETICS 221 (1990) ...
Laboratory 4 Patterns of Inheritance (human)
Laboratory 4 Patterns of Inheritance (human)

... egg went through meiosis shuffling the genes around by independent assortment of the homologous pairs and crossing over of genetic information between non-sister chromatids, even children of the same parents will receive a different set of genes from each parent. Identical twins are an exception bec ...
Structure and functions of lampbrush chromosomes
Structure and functions of lampbrush chromosomes

... constitutes a part of the chromosome axis. It is extensible as well as contractible. The contractibility of the loop results in the contraction and dilation of the chromomere (Angelier, et al. 1984, 1990; Macgregor, 1987; Chelysheva, et al. 1990; Morgan, 2002). A diagram of LBC structure is presente ...
A Sex Chromosome Rearrangement in a Human XX
A Sex Chromosome Rearrangement in a Human XX

... in U7should be present in three copies (one each from the paternal X, the paternal Y, and a maternal X chromosome). Those pseudoautosomal loci distal to U7 would be present in only two copies (one from the paternal Y chromosome and one from a maternal X chromosome). We therefore determined the copy ...
What is genetics?
What is genetics?

... • Eye color, nose shape, and many other physical features are some of the traits that are inherited from parents. • An organism is a collection of traits, all inherited from its parents. ...
Taq DNA Polymerase
Taq DNA Polymerase

... Start the PCR program. Once the thermal cycler has reached 94°C, place the PCR tubes in the thermal cycler. In many cases, this simplified hot start improves the specificity of the PCR. Note: After amplification, samples can be stored overnight at 2–8°C, or at –20°C for longer storage. 7. PCR produc ...
Printable version - Chromosome 18 Registry and Research Society
Printable version - Chromosome 18 Registry and Research Society

... This diagram depicts the structure of a chromosome. What looks like squatty little things under a microscope are actually very long linear chemical structures that have been precisely packaged. The chemical structure called DNA is shown in red and blue. This is the DNA double helix. The pairs of blu ...
Control of the acetamidase gene of Mycobacterium smegmatis by
Control of the acetamidase gene of Mycobacterium smegmatis by

... Much interest has been focussed on this system for its potential use in mycobacterial genetic studies. The availability of an inducible promoter which functions well in mycobacteria including the important human pathogen Mycobacterium tuberculosis would be extremely useful. The acetamidase system ha ...
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Designer baby

Designer baby is a term that refers to the product of a genetically engineered baby. These babies are ""designed"" (fixed/changed) while still in the womb to achieve more desired looks, skills, or talents.
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