You may have heard the terms saturated and unsaturated in rela
You may have heard the terms saturated and unsaturated in rela

... are single bonds, the lipid is a saturated fat. If one or more of these bonds is a double bond, the lipid is an unsaturated fat. Most animal fats are saturated, and most oils from plants are unsaturated. Diets high in saturated fats have been linked to heart disease. Lipids in the butter in the phot ...
week 7_lipid - UniMAP Portal
week 7_lipid - UniMAP Portal

... obtained by the ingestion of LDL by foam cells- directly correlated with high risk for coronary heart disease.  High plasma HDL- low risk for coronary artery disease.  Liver cells are the only cells that possess HDL receptors. ...
pract_cholesterol
pract_cholesterol

Cholesterol
Cholesterol

... Lipid catabolism where lipids become: ...
Lecture 3
Lecture 3

... •! Leading cause of death •! High levels of cholesterol increase the chances of developing these types of disease •! These diseases are more prevalent as people age, one reason is that the rate at which cholesterol is metabolized, decreases with age •! Females have lower levels of cholesterol ...
Mutation in the EGFP domain of LDL receptor
Mutation in the EGFP domain of LDL receptor

... Laboratory Medicine, Genetics, and Immunobiology, Yale University School of Medicine, New Haven, Conn; and Isfahan University of Medical Sciences, Isfahan, Iran. Mutation in the EGFP domain of LDL receptor-related protein 6 (LRP6R611C) is associated with hypercholesterolemia and early-onset atherosc ...

Low-density lipoprotein

Low-density lipoprotein (LDL) is one of the five major groups of lipoproteins. These groups, from least dense to most dense, are: chylomicrons , very low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), LDL, and High Density Lipoprotein (HDL), all of them, particles far smaller than human cells. In nutrition, LDL is sometimes referred to as ""the bad cholesterol.""Lipoproteins transfer fats around the body in the water outside cells, can be sampled from blood and allow fats to be taken up by the cells of the body by receptor-mediated endocytosis. Lipoproteins are complex particles composed of multiple proteins which transport all fat molecules (lipids) around the body within the water outside cells. They are typically composed of 80-100 proteins/particle (organized by a single ApoB for LDL and the larger particles) and transporting about 3,000 to 6,000 fat molecules/particle. The fats carried include cholesterol, phospholipids, and triglycerides; amounts of each vary considerably. LDL particles pose a risk for cardiovascular disease when they invade the endothelium and become oxidized, since the oxidized forms are more easily retained by the proteoglycans. A complex set of biochemical reactions regulates the oxidation of LDL particles, chiefly stimulated by presence of necrotic cell debris and free radicals in the endothelium. Increasing concentrations of LDL particles are strongly associated with increasing amounts of atherosclerosis within the walls of arteries over time, eventually resulting in sudden plaque ruptures and triggering clots within the artery opening, or a narrowing or closing of the opening, i.e. cardiovascular disease, stroke, and other vascular disease complications.LDL particles (though far different from cholesterol per se) are sometimes referred to as bad cholesterol because they can transport their content of fat molecules into artery walls, attract macrophages, and thus drive atherosclerosis. In contrast, HDL particles (though far different from cholesterol per se) are often called good cholesterol or healthy cholesterol because they can remove fat molecules from macrophages in the wall of arteries.A hereditary form of high LDL is familial hypercholesterolemia (FH). High LDL is termed hyperlipoproteinemia type II (after the dated Fredrickson classification).