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Lily Saadat - Tangier's Disease
Lily Saadat - Tangier's Disease

...   Caused in some families by mutation in the ABC1 gene (like Tangier!)   Additional mutations in the apolipoprotein A1 gene (maps to 11q23.3)   Concentrations of alpha-lipoproteins or high-density lipoprotein (HDL) are ...
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... people lacking the Duffy antigen on the surface of their red cells do not get malaria from P. vivax. This is because P. vivax merozoites bind to the Duffy antigen as a first step in invading the red cells; if the antigen is not there, they can't invade. There is also the well-known example of the pr ...
Good Evening Ladies and Gentlemen. Evolution is one of those
Good Evening Ladies and Gentlemen. Evolution is one of those

... Evolution is the “change over time in the proportion of individual organisms differing in one or more inherited traits”. Looking at that in more simple terms, evolution, and more specifically, Biological evolution, is simply the change in a species over time. This can be relatively small changes, su ...
Scientific researcher for the project `Metagenetic upgrading of
Scientific researcher for the project `Metagenetic upgrading of

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BIOL 433 Plant Genetics Term 1, 2005

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Hox

... Hox gene products activate genes responsible for making a particular structure. Mutations in Hox genes Mutation of Hox gene antp bx, pbx, and abx ...
SPECIES AND SPECIATION
SPECIES AND SPECIATION

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CHAPTER 1: Introduction During the past century some major
CHAPTER 1: Introduction During the past century some major

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Modified Mendelian Ratios II

... Writing assignment on ТThe Monk in the GardenУ by Robin Marantz Henig Choose one of the following th ree topic areas to write a 2-4 page, doublespaced, typed essay. This assignment is worth 75 pts (out o f a possible 1000). You will be graded on: how w ell did you answer the q uestions? (40); do you ...
Gene technology
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Chapters 11-13: Classical Genetics

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Gene Section RNF139 (translocation in renal carcinoma, chromosome 8 gene)

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... DNA, RNA (e.g. RNAi), protein (prion), & modifications (e.g. 5mC) “Horizontal” (generally between species) transduction, transformation, transgenic “Vertical” Mitosis: duplication & division (e.g. somatic) Meiosis/fusion: diploid recombination, reduction Maternal (e.g. mitochondrial) ...
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... Genes determine inherited traits by carrying the information that is passed from parents to offspring. These genes carry information that each cell of an organism needs in order to grow and perform its activities. Different versions of genes are called alleles. The specific combination of alleles is ...
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... Alleles interact to produce traits.  Phenotype – describes the actual characteristics that can be observed. (What you can see in the mirror.)  Height, eye color, size of your feet  Genotype – the genes an organism has. Your genotype isn’t always obvious by looking at your phenotype. You could ha ...
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Exam 2 (pdf - 592.95kb)
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... Use the following information to answer Questions 13 and 14. One of the human blood groups is the MN group. There are two alleles, LM and LN, at this gene locus which determine the presence of an antigen, M or N, on the surface of the red blood cells. The heterozygote LMLN has a different phenotype ...
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... 16- The human genome consists of approximately how many DNA base pairs? a- 30,000 b- 3,000,000 c- 300,000,000 d- 3,000,000,000 17- The fraction of the human genome that actually codes for proteins is about a- 2% b- 20% c- 98% d- 100% 18- Cutting DNA into small pieces that can be sequenced is accompl ...
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111-297-1-SM

... protein (Bryan et al., 2000; Jia et al., 2000).Additional evidence has been accumulated from other host and parasite systems to support the role of R genes in direct recognition of pathogen-signaling molecules in nature. Meanwhile, research in this area has also led to the development of both domina ...
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... to be used should be close to gene of interest in order to ensure that only a minor fraction of the selected individuals will be recombinants. Generally, not only a single marker but rather two markers are used in order to reduce the chances of an error due to homologous recombination. Since humans ...
Eukaryotic Gene Regulation
Eukaryotic Gene Regulation

... level 1: Regulation at the chromatin level • Histones are proteins that surround and “protect” DNA and form chromatin • While the histones conceal the DsDNA so no RNA/DNA polymerase can bind to it. • Chromatin modification can be considered to be the first step of gene regulation: – Prerequisite fo ...
The Genetic Basis of Complex Inheritance
The Genetic Basis of Complex Inheritance

... h2 = (M’ - M)/(M* - M) • In general, h2 < H2 . They are equal only when the alleles affecting the trait are additive in their effects = heterozygous phenotype is exactly intermediate between homozygous dominant and recessive ...
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Microevolution

Microevolution is the change in allele frequencies that occur over time within a population. This change is due to four different processes: mutation, selection (natural and artificial), gene flow, and genetic drift. This change happens over a relatively short (in evolutionary terms) amount of time compared to the changes termed 'macroevolution' which is where greater differences in the population occur.Population genetics is the branch of biology that provides the mathematical structure for the study of the process of microevolution. Ecological genetics concerns itself with observing microevolution in the wild. Typically, observable instances of evolution are examples of microevolution; for example, bacterial strains that have antibiotic resistance.Microevolution over time leads to speciation or the appearance of novel structure, sometimes classified as macroevolution. Macro and microevolution describe fundamentally identical processes on different scales.
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