Slide 1
... DNA METHYLATION • When CpG dinucleotides are hypermethylated in a given locus, neighboring genes are usually silent • CpG hypomethylation correlates with gene expression me ...
... DNA METHYLATION • When CpG dinucleotides are hypermethylated in a given locus, neighboring genes are usually silent • CpG hypomethylation correlates with gene expression me ...
Repair of Damaged DNA
... pyrimidine dimers (distort the template strand) • Thymine dimers are repaired in all organisms ...
... pyrimidine dimers (distort the template strand) • Thymine dimers are repaired in all organisms ...
Patterns of Inheritance Chapter 12
... Polygenic inheritance occurs when multiple genes are involved in controlling the phenotype of a trait. The phenotype is an accumulation of contributions by multiple genes. These traits show continuous variation and are referred to as quantitative traits. For example – human height ...
... Polygenic inheritance occurs when multiple genes are involved in controlling the phenotype of a trait. The phenotype is an accumulation of contributions by multiple genes. These traits show continuous variation and are referred to as quantitative traits. For example – human height ...
Monohybrid cross
... Polygenic inheritance occurs when multiple genes are involved in controlling the phenotype of a trait. The phenotype is an accumulation of contributions by multiple genes. These traits show continuous variation and are referred to as quantitative traits. For example – human height ...
... Polygenic inheritance occurs when multiple genes are involved in controlling the phenotype of a trait. The phenotype is an accumulation of contributions by multiple genes. These traits show continuous variation and are referred to as quantitative traits. For example – human height ...
A Short History of DNA Technology
... • An automated DNA sequencer is developed • A screening test for Huntington’s disease is developed using restriction fragment length markers. ...
... • An automated DNA sequencer is developed • A screening test for Huntington’s disease is developed using restriction fragment length markers. ...
Chapter 12: PowerPoint
... Polygenic inheritance occurs when multiple genes are involved in controlling the phenotype of a trait. The phenotype is an accumulation of contributions by multiple genes. These traits show continuous variation and are referred to as quantitative traits. For example – human height ...
... Polygenic inheritance occurs when multiple genes are involved in controlling the phenotype of a trait. The phenotype is an accumulation of contributions by multiple genes. These traits show continuous variation and are referred to as quantitative traits. For example – human height ...
Variation, probability, and pedigree
... Variation, probability, and pedigree • Gamete production is source of variation and genetic diversity, an advantage of sex. – As a result of segregation and independent assortment, lots of combinations possible. – 2n possibilities exist for diploids where n = haploid number of chromosomes • In human ...
... Variation, probability, and pedigree • Gamete production is source of variation and genetic diversity, an advantage of sex. – As a result of segregation and independent assortment, lots of combinations possible. – 2n possibilities exist for diploids where n = haploid number of chromosomes • In human ...
Introduction to Genetics Terms
... Male____ genotype is XY Multiple alleles____ a type of gene that is determined by more than two alleles, such as in blood types Nondisjunction____ process that takes place when a chromosome pair fails to separate correctly during meiosis; this can result in a wrong number of chromosomes One-hundred_ ...
... Male____ genotype is XY Multiple alleles____ a type of gene that is determined by more than two alleles, such as in blood types Nondisjunction____ process that takes place when a chromosome pair fails to separate correctly during meiosis; this can result in a wrong number of chromosomes One-hundred_ ...
The Genetical Theory of Natural Selection (ch. 1-2)
... Charles Darwin accepted the fusion or blending theory of inheritance, just as all men accept many of the undisputed beliefs of their time, is universally admitted. That his acceptance of this theory had an important influence on his views respecting variation, ...
... Charles Darwin accepted the fusion or blending theory of inheritance, just as all men accept many of the undisputed beliefs of their time, is universally admitted. That his acceptance of this theory had an important influence on his views respecting variation, ...
Two v-erbA-related genes, named ear-2 and ear
... insert is used as poly (A) addition signal. If it is, the 5' noncoding sequence must be extremely long (about 2.5-kbp), since the ear-3 mRNA are 4.6-kb and 4.8-kb long. The free energy of a possible secondary structure at the 5' untranslated region (32) was calculated to be -207.4 kcal. Thus, this r ...
... insert is used as poly (A) addition signal. If it is, the 5' noncoding sequence must be extremely long (about 2.5-kbp), since the ear-3 mRNA are 4.6-kb and 4.8-kb long. The free energy of a possible secondary structure at the 5' untranslated region (32) was calculated to be -207.4 kcal. Thus, this r ...
Asexual vs. Sexual Reproduction
... The egg is fertilized by sperm outside the female The female lays the eggs and then the male fertilizes them. Fish and some amphibians Plants and fungi (pollen and spores) ...
... The egg is fertilized by sperm outside the female The female lays the eggs and then the male fertilizes them. Fish and some amphibians Plants and fungi (pollen and spores) ...
Finding the Fault in Nick`s Genome – sp2015
... Nicholas was born October 2004, the fifth child in the family. Before his 2nd birthday, an abscess formed near his rectum. Over the next 3 years holes appeared in his colon and large intestine, and stool leaked into his abdomen. The symptoms resembled irritable bowel disease (IBD) or Crohn's disease ...
... Nicholas was born October 2004, the fifth child in the family. Before his 2nd birthday, an abscess formed near his rectum. Over the next 3 years holes appeared in his colon and large intestine, and stool leaked into his abdomen. The symptoms resembled irritable bowel disease (IBD) or Crohn's disease ...
Recombinant Baculovirus:
... SW480 cells were transduced with baculovirus on 96-well plate. A plate reader was used to measure the fluorescein readings from time to time to determine the effect of viral incubation time on gene expression. RNA was extracted from transduced cells and Reverse Transcriptase Polymerase Chain Re ...
... SW480 cells were transduced with baculovirus on 96-well plate. A plate reader was used to measure the fluorescein readings from time to time to determine the effect of viral incubation time on gene expression. RNA was extracted from transduced cells and Reverse Transcriptase Polymerase Chain Re ...
LEARNING GOALS - CELL CYCLE, MITOSIS AND MEIOSIS
... 3. Cyclins and cyclin-dependent kinases control the cell cycle. ✘Knowledge of any one cyclin-CdK pair or growth factor is beyond the scope of the course and the AP Exam. 4. Mitosis alternates with interphase in the cell cycle. 5. When a cell specializes, it often enters into a stage where it no long ...
... 3. Cyclins and cyclin-dependent kinases control the cell cycle. ✘Knowledge of any one cyclin-CdK pair or growth factor is beyond the scope of the course and the AP Exam. 4. Mitosis alternates with interphase in the cell cycle. 5. When a cell specializes, it often enters into a stage where it no long ...
Pipe cleaner DNA
... the thymine (green) and cytosine (yellow) pieces are folded in half. Make marks on the tape every 3 cm (15 total) for 5 codons of bases. Lay a pipe cleaner piece on the first mark perpendicular to the tape, so that it overlaps exactly one half of the tape. This step is repeated with random colors un ...
... the thymine (green) and cytosine (yellow) pieces are folded in half. Make marks on the tape every 3 cm (15 total) for 5 codons of bases. Lay a pipe cleaner piece on the first mark perpendicular to the tape, so that it overlaps exactly one half of the tape. This step is repeated with random colors un ...
Human genetics
... Normal human nucleated cells contain 46 chromosomes arranged in 22 homologous pairs of autosomal chromosomes in addition to one pair of sex chromosomes that could be similar (i.e. XX) or different (i.e. XY). This arrangement into pairs, based on the position of the centromere and on the length of th ...
... Normal human nucleated cells contain 46 chromosomes arranged in 22 homologous pairs of autosomal chromosomes in addition to one pair of sex chromosomes that could be similar (i.e. XX) or different (i.e. XY). This arrangement into pairs, based on the position of the centromere and on the length of th ...
Chromosomal Basis of Inheritance Linked
... Chromosomal Basis of Inheritance Linked Genes Sex-linked Genes ...
... Chromosomal Basis of Inheritance Linked Genes Sex-linked Genes ...
chapter_14_human_heredity
... • It is caused by a defective version of the gene that codes for muscle protein. ...
... • It is caused by a defective version of the gene that codes for muscle protein. ...
STUDY SUGGESTIONS These are just guidelines! Anything from
... What is the difference between a baby being small-for-date versus premature? Describe the different states of arousal in a newborn and the relative amount of time spent in each. What regulates the sleep-wake cycle in the newborn period? Name some of the newborn reflexes and what the response of the ...
... What is the difference between a baby being small-for-date versus premature? Describe the different states of arousal in a newborn and the relative amount of time spent in each. What regulates the sleep-wake cycle in the newborn period? Name some of the newborn reflexes and what the response of the ...
Lecture 18
... a. RNA precedes DNA so we can consider their differences in terms of natural selection b. Diagram of structure c. Phenotypic change from RNA to DNA i. 2' OH --> 2' H ii. U --> T d. New functions i. SS --> DS independently ii. A = U is A = T iii. 2' OH bulk blocks DS iv. All of DNA is double stranded ...
... a. RNA precedes DNA so we can consider their differences in terms of natural selection b. Diagram of structure c. Phenotypic change from RNA to DNA i. 2' OH --> 2' H ii. U --> T d. New functions i. SS --> DS independently ii. A = U is A = T iii. 2' OH bulk blocks DS iv. All of DNA is double stranded ...
preimplantation genetic diagnosis
... embryo biopsy at the cleavage stage and sexing with Y-specific DNA amplification. A few years later, the introduction of fluorescent in situ hybridization (FISH), a method in which fluorescent labeled, chromosome-specific probes are hybridized to metaphase or interphase chromosomes were reported, al ...
... embryo biopsy at the cleavage stage and sexing with Y-specific DNA amplification. A few years later, the introduction of fluorescent in situ hybridization (FISH), a method in which fluorescent labeled, chromosome-specific probes are hybridized to metaphase or interphase chromosomes were reported, al ...
Gene testing - Margie Patlak
... In the late 1960s, a useful molecular tool came to the rescue of these frustrated researchers, thanks to a series of studies by Werner Arber, in Switzerland, and Hamilton Smith, at Johns Hopkins University. These investigators were studying what at first seemed to be an unrelated problem. They were ...
... In the late 1960s, a useful molecular tool came to the rescue of these frustrated researchers, thanks to a series of studies by Werner Arber, in Switzerland, and Hamilton Smith, at Johns Hopkins University. These investigators were studying what at first seemed to be an unrelated problem. They were ...
Presentation
... • Would you expect any of their children to be colorblind? • What happens when the carrier daughters grow up and marry men who have normal vision? – Do that cross at your seats….Can they have colorblind children? Colorblind daughters? Colorblind sons? ...
... • Would you expect any of their children to be colorblind? • What happens when the carrier daughters grow up and marry men who have normal vision? – Do that cross at your seats….Can they have colorblind children? Colorblind daughters? Colorblind sons? ...
Transposons - iPlant Pods
... • Subtle impact on the expression of many genes • Produces stress-inducible networks (cold, salt, others?) • Generates dominant alleles Naito et al, Nature, 2009 ...
... • Subtle impact on the expression of many genes • Produces stress-inducible networks (cold, salt, others?) • Generates dominant alleles Naito et al, Nature, 2009 ...
Plant Speciation REVIEW
... restricted outcrossing (exchange of pollen between individuals) impedes interspecific hybridization. Reproductive isolation between species may be incomplete, however, particularly in groups that have recently undergone multiple speciation events or those that have long generation times. This incomp ...
... restricted outcrossing (exchange of pollen between individuals) impedes interspecific hybridization. Reproductive isolation between species may be incomplete, however, particularly in groups that have recently undergone multiple speciation events or those that have long generation times. This incomp ...