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University of Bucharest, Faculty of Biology, Molecular Biology Center
University of Bucharest, Faculty of Biology, Molecular Biology Center

... neutrophiles across membranes to destroy invading pathogens [6; 9; 10]. The molecular basis of BLAD is a single point mutation (A-G) at position 383 in the cDNA of the CD18 gene. This mutation results in a substitution of a glycine for an aspartic acid at position 128 in the D128G protein [2; 5; 8; ...
Woods Hole – Zebrafish Genetics and Development Bioinformatics
Woods Hole – Zebrafish Genetics and Development Bioinformatics

... BLAST, batch download potential promoter sequences for each of these transcripts, search through these promoter sequences for enriched motifs, and visualize the location of the motifs on the promoters (just a bit advanced) Requirements: Terminal, Python, Matplotlib (all native on MacOSX) Protocols: ...
Foundations of Biology - Geoscience Research Institute
Foundations of Biology - Geoscience Research Institute

... The authors who reported the presence of mitochondrial genes in amitochondrial eukaryotes all reinterpreted prevailing theory in saying that mitochondria must have been present then lost after they had transferred some of their genetic information to the nucleus. The hydrogenosome, a structure invol ...
The Amazing Sperm Race - National Math and Science Initiative
The Amazing Sperm Race - National Math and Science Initiative

... homologous chromosomes and Meiosis II involves the separation of the sister chromatids. • In Meiosis I the homologous chromosomes line up on top of each other during (Metaphase I), and during Meiosis II they line up single file (Metaphase II). • Meiosis I involves crossing over, and Meiosis II doe ...
Ancient Structure in Africa Unlikely to Explain Neanderthal and Non
Ancient Structure in Africa Unlikely to Explain Neanderthal and Non

... result is also valid for the ancient structure model with no ancestral gene flow (m 5 0). Such a model is equivalent to a model with no gene flow but in which the African population is the outgroup to Neanderthals and non-Africans. Equation (3) is also valid for the ancient structure model with larg ...
The Genetic Control of Apomixis: Asexual Seed Formation
The Genetic Control of Apomixis: Asexual Seed Formation

... rapidly fix desirable genotypes in crop species could accelerate agricultural breeding strategies. The potential of apomixis as a nextgeneration breeding technology has contributed to increasing interest in the mechanisms controlling apomixis. In this review, we discuss the progress made toward under ...
The ara Operon - University of Pennsylvania
The ara Operon - University of Pennsylvania

... araI, transcription of araB, A and D ensues. CAP stands for catabolite activator protein which is also involved in arabinose regulation, the same way it did in the lac operon. This model actually proposes two operators, O1 and O2 that are also the binding sites of AraC. When AraC binds to any of the ...
Cloning and Expression of Cellulosimicrobium cellulans β
Cloning and Expression of Cellulosimicrobium cellulans β

... Endo-1,3-β-glucanases (EC 3.2.1.6 and EC 3.2.1.39) are widely distributed among bacteria and higher plants [1]. These enzymes catalyse the hydrolysis of β-1,3-glucan component found in the yeast cell wall and other β-1,3glucans such as laminarin, curdlan and pachyman [2,3]. The bacterium Cellulosimi ...
genetic disorders associated with macrocephaly
genetic disorders associated with macrocephaly

... may occasionally be associated with hydrocephalus or true megalencephaly. Noonan syndrome is caused by mutations in the PTPN11 gene (12q24.1) in 50%, KRAS gene (12p12.1) in less than 5%, SOS1 gene (2p22-p21) in 10%, and RAF1 gene (3p25) in 3-17% of cases. Cardiofaciocutaneous (CFC) syndrome is chara ...
Genetic diversity and epidemiology of infectious hematopoietic
Genetic diversity and epidemiology of infectious hematopoietic

... serum (MEM-10).Infected cultures were incubated at 15°C until the monolayer started to slough off, typically 6 or 7 d post-inoculation. Infected cells and media for each virus isolate were centrifuged and 1.0 m1 aliquots of supernatant were frozen at -7O0C. These served as the virus stock used in th ...
Saccharomycopsis fibuligera and Yarrowia lipol`ica
Saccharomycopsis fibuligera and Yarrowia lipol`ica

... Colonies of the intergeneric hybrid between A6 and Y. lipobtica 21501-4B also showed a clear halo around the colony on YPSS. On this medium, colonies of Y. lipobtica 21501-4B did not show a halo; this result was expected as Y. lipobtica is not amylolytic. Strains A6, A18 and A6/21501-4B showed a sim ...
Association between toluene diisocyanate-induced aspartic acid at position 57
Association between toluene diisocyanate-induced aspartic acid at position 57

... TDI-induced asthma exhibit the CD8+ phenotype and produce interleukin-5 (IL-5) and interferon-gamma [22]. Whatever the exact mechanism of the association DQTDI-induced asthma may be, the data are consistent with the hypothesis that at least two risk factors exist for TDIinduced asthma, exposure to t ...
PDF
PDF

... H3K27me3 mark targets both, genes and repetitive elements and is anti-correlated with transcriptional activity. We show that H3K27me3 distribution over its targets is not uniform, but can be grouped into several different clusters that correlate with different levels of repression. Furthermore, we d ...
Mary Ann Osley*, Alastair Fleming, and Cheng
Mary Ann Osley*, Alastair Fleming, and Cheng

... ubiquitin proteases (Ubps) in eukaryotic cells (16 in yeast and several hundred in vertebrates){Amerik, 2000 #1}{Hochstrasser, 1995 #38}{Wilkinson, 1997 #109}. These proteases act by hydrolyzing the linkage between ubiquitin and the target protein or between individual ubiquitin molecules in the cas ...
Evolutionary approaches to autism
Evolutionary approaches to autism

... theories to arrive at a sensible account for maintenance of a highly heritable disorder, which is characterized by low reproductive success? ...
The R2R3 MYB Transcription Factor GhMYB109 Is
The R2R3 MYB Transcription Factor GhMYB109 Is

... induces a single trichome from the epidermis of Arabidopsis seeds (Wang et al. 2004b). GhMYB25, a homolog of AmmIXTA/AmmYBML1 that controls petal conical cell and trichome differentiation in Antirrhinum majus, is predominately expressed in ovules and fiber cell initials (Wu et al. 2006). A recent wo ...
Evolving swarm intelligence for task allocation in a real time strategy
Evolving swarm intelligence for task allocation in a real time strategy

... Note that LA-DCOP and Swarm-GAP are very similar regarding the token-based protocol for coordination. The difference in both algorithms lies in the way the agents allocate tasks. In LA-DCOP, the process corresponds to solving an instance of the BKP whereas in Swarm-GAP, agents allocate tasks in a pr ...
IVRI OB 1809
IVRI OB 1809

... One proviso must be added to this definition: that conditions outside the organisms be not changed. In nature the differences between organllims depend on differences outside as well as inside them. Smaller size may be due !o bad heredity or bad food. We therefore separate these two factors as Genot ...
Doing Without Representations Which Specify What To Do
Doing Without Representations Which Specify What To Do

... The message that `what is there' actually consists of many different things—depending on how you focus—has often been difficult to digest. The common response is to ask which of the possible descriptions is the `real' or `fundamental' one. Heider once said: "The fact of multiple focus furnishes phil ...
Prof. Kamakaka`s Lecture 2 Notes
Prof. Kamakaka`s Lecture 2 Notes

... Relevance of model organisms to humans. Over 60 per cent of the human disease genes have counterparts in the fly and worm. About 1500 gene families are conserved in all animals. Genes affecting immune system etc, are less likely to have counterparts in simple animals. For these systems, we require c ...
(FISH) or Immunohistochemistry (IHC)
(FISH) or Immunohistochemistry (IHC)

... thyroid, lung, salivary gland, stomach, colon and prostate cancer, it has been reported that approximately one-third of breast cancer patients overexpress HER-2/neu. This overexpression appears to be associated with more aggressive disease and usually results from amplification (multiple extra copie ...
Efficient and Accurate Clustering for Large
Efficient and Accurate Clustering for Large

... represents one linkage group from the species whose sequence data is obtained from the mapping population. Formally, we are given m markers measured across n individuals in the mapping population and aim to find ordered, connected clusters (linkage groups) C1 , ..., Ck . The entries of a marker feat ...
Reciprocal deletion and duplication at 2q23.1 indicates a
Reciprocal deletion and duplication at 2q23.1 indicates a

... syndrome. We provide data to support MBD5 as the critical gene for both 2q23.1 deletion and duplication syndromes and demonstrate that appropriate dosage of MBD5 is critical for normal development. Refinement of the 2q23.1 duplication syndrome critical region Given the establishment of MBD5 haploins ...
A xylem-specific cellulose synthase gene from aspen (Populus
A xylem-specific cellulose synthase gene from aspen (Populus

A String-based Model for Simple Gene Assembly
A String-based Model for Simple Gene Assembly

... differently in their two types of nuclei. In micronuclei, genes are split into blocks (called MDSs), placed in a shuffled order on the chromosome, separated by noncoding blocks. Moreover, some of the MDSs are even presented in an inverted form. In macronuclei however, genes are contiguous sequences ...
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Genome (book)

Genome: The Autobiography of a Species in 23 Chapters is a 1999 popular science book by Matt Ridley, published by Fourth Estate.
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