Genetic Architecture of Maize Kernel Composition in the Nested
... including opaque2 (o2) which increases lysine content (Mertz et al., 1964), amylose-free waxy1 (wx1) (Lambert, 2001), sugary1 (su1), sugary enhancer (se), and shrunken2 (sh2) which are responsible for sweet corn (Schultz and Juvik, 2004), and linoleic acid1 (ln1) with an altered fatty acid ratio (Po ...
... including opaque2 (o2) which increases lysine content (Mertz et al., 1964), amylose-free waxy1 (wx1) (Lambert, 2001), sugary1 (su1), sugary enhancer (se), and shrunken2 (sh2) which are responsible for sweet corn (Schultz and Juvik, 2004), and linoleic acid1 (ln1) with an altered fatty acid ratio (Po ...
The Evolutionary Reduction Principle for Linear Variation in Genetic
... includes gene conversion, methylation, deletions, duplications, insertions, transpositions, and other chromosomal alterations. These two processes, augmented by a third — the randomness of sampling in finite populations — provide the basis for our causal explanations of the characteristics of organ ...
... includes gene conversion, methylation, deletions, duplications, insertions, transpositions, and other chromosomal alterations. These two processes, augmented by a third — the randomness of sampling in finite populations — provide the basis for our causal explanations of the characteristics of organ ...
Two-Component System of Mycobacterium Tuberculosis
... International License, which allows users to download, copy and build upon published articles even for commercial purposes, as long as the author and publisher are properly credited. ...
... International License, which allows users to download, copy and build upon published articles even for commercial purposes, as long as the author and publisher are properly credited. ...
Direct Deletion Analysis in Two Duchenne Muscular Dystrophy
... locus STR 7A for the proband (II2), who should have been heterozygous (allels b and c) (Fig. 2a STR 7A). The hemizygosity was suspected because a similar pattern to that obtained for the father was observed in the proband. Also, a reduction in the signal was seen where the maternal allele (2bp light ...
... locus STR 7A for the proband (II2), who should have been heterozygous (allels b and c) (Fig. 2a STR 7A). The hemizygosity was suspected because a similar pattern to that obtained for the father was observed in the proband. Also, a reduction in the signal was seen where the maternal allele (2bp light ...
1 - F
... Tutorial times to be announced. PREVIOUSLY Deterministic evolution, via natural selection. TODAY Inbreeding: does not cause evolution on its own; -- affects arrangement of genes in populations; & has important fitness effects. ...
... Tutorial times to be announced. PREVIOUSLY Deterministic evolution, via natural selection. TODAY Inbreeding: does not cause evolution on its own; -- affects arrangement of genes in populations; & has important fitness effects. ...
evolution - Santa Fe Institute
... the face of mutations and environmental variation? And what are the evolutionary consequences of robustness? The amount of phenotypic diversity within or among populations can vary significantly. For example, scutellar bristle number in Drosophila melanogaster rarely deviates from the canonical four ...
... the face of mutations and environmental variation? And what are the evolutionary consequences of robustness? The amount of phenotypic diversity within or among populations can vary significantly. For example, scutellar bristle number in Drosophila melanogaster rarely deviates from the canonical four ...
Early frameshift alleles of zebrafish tbx5a that fail to
... Generation of tbx5b mutants in the tbx5aΔ5 and tbx5aΔ10 background to discriminate the possible contribution of tbx5b to the tbx5a null mutant phenotype. Further, complementation analysis with tbx5a alleles that feature bigger deletions are required to evaluate if tbx5aΔ5 and tbx5aΔ10 are null allel ...
... Generation of tbx5b mutants in the tbx5aΔ5 and tbx5aΔ10 background to discriminate the possible contribution of tbx5b to the tbx5a null mutant phenotype. Further, complementation analysis with tbx5a alleles that feature bigger deletions are required to evaluate if tbx5aΔ5 and tbx5aΔ10 are null allel ...
Application Note: Targeted sequencing and chromosomal haplotype
... using just one primer pair complementary to a short locusspecific sequence. TLA is a strategy to selectively amplify complete loci on the basis of crosslinking physically proximal sequences. Unlike other targeted sequencing methods, TLA works without prior detailed locus information, as one primer p ...
... using just one primer pair complementary to a short locusspecific sequence. TLA is a strategy to selectively amplify complete loci on the basis of crosslinking physically proximal sequences. Unlike other targeted sequencing methods, TLA works without prior detailed locus information, as one primer p ...
The importance of genetic influences in asthma REVIEW H. Los* , G.H. Koppelman*
... immunoglobulin E (IgE), specific IgE directed against different allergens, skin test reactivity against common aeroallergens and eosinophilia. Other phenotypes associated with asthma are allergic rhinitis and atopic dermatitis. It is, however, questionable whether these traits have a common pathway ...
... immunoglobulin E (IgE), specific IgE directed against different allergens, skin test reactivity against common aeroallergens and eosinophilia. Other phenotypes associated with asthma are allergic rhinitis and atopic dermatitis. It is, however, questionable whether these traits have a common pathway ...
Coordination of replication and transcription along a Drosophila
... hybridized labeled poly(A)-containing mRNA from asynchronous cells to the genomic microarray, using total genomic DNA as a control. The resulting pattern of expression along the chromosome was in close agreement with the predictions of inter- and intragenic sequences from the Drosophila annotation p ...
... hybridized labeled poly(A)-containing mRNA from asynchronous cells to the genomic microarray, using total genomic DNA as a control. The resulting pattern of expression along the chromosome was in close agreement with the predictions of inter- and intragenic sequences from the Drosophila annotation p ...
Preview Sample 2
... Several advantages exist to using peas for the study of inheritance: (1) Peas have a fairly rapid generation time (at least two generations per year if grown in the field, three or four generations per year if grown in greenhouses. (2) Peas can either self-fertilize or be artificially crossed by an ...
... Several advantages exist to using peas for the study of inheritance: (1) Peas have a fairly rapid generation time (at least two generations per year if grown in the field, three or four generations per year if grown in greenhouses. (2) Peas can either self-fertilize or be artificially crossed by an ...
Inheritance of White Colour in Alpacas
... Australian alpaca herds, the results described herein are applicable to all alpacas, both huacaya and suri. Breeders will be able to use this information to increase the predictability of colour outcomes in their breeding programs. Background This project was designed to meet the growing need for kn ...
... Australian alpaca herds, the results described herein are applicable to all alpacas, both huacaya and suri. Breeders will be able to use this information to increase the predictability of colour outcomes in their breeding programs. Background This project was designed to meet the growing need for kn ...
Imposition of Crossover Interference through the
... As mentioned in the Introduction, a number of observations indicate that synapsis initiates at the sites of recombination events. But does synapsis initiate specifically at the sites of COs? To address this question, we determined whether Zip2 foci demonstrate interference, a property of COs, but no ...
... As mentioned in the Introduction, a number of observations indicate that synapsis initiates at the sites of recombination events. But does synapsis initiate specifically at the sites of COs? To address this question, we determined whether Zip2 foci demonstrate interference, a property of COs, but no ...
The evolution of mutation rate in sexual populations during
... hitchhiking, which is highly sensitive to recombination. However, under conditions of genetic similarity, typical for expanding range margins, the evolution of mutation rates in sexual populations might be possible. Using an individual-based model we show that natural selection leads to co-evolution ...
... hitchhiking, which is highly sensitive to recombination. However, under conditions of genetic similarity, typical for expanding range margins, the evolution of mutation rates in sexual populations might be possible. Using an individual-based model we show that natural selection leads to co-evolution ...
Molecular Design of Expression Systems
... upon interaction with a corresponding specific repressor protein. This interaction may be influenced by adjusting the temperature (ts regulatory mutant) or the composition (inducer or corepressor concentration) of the growth medium in order to switch from low to high promoter activity. Limitations o ...
... upon interaction with a corresponding specific repressor protein. This interaction may be influenced by adjusting the temperature (ts regulatory mutant) or the composition (inducer or corepressor concentration) of the growth medium in order to switch from low to high promoter activity. Limitations o ...
Complete genome sequence of the thermophilic Thermus sp
... isomerases), pulp and paper manufacturing (e.g. xylanases) as well as animal feed and human food production (amino acid and vitamin synthesis) [13, 14]. Here, we present a summary of classification and a set of features for Thermus sp. CCB_US3_UF1, together with the description of the complete genom ...
... isomerases), pulp and paper manufacturing (e.g. xylanases) as well as animal feed and human food production (amino acid and vitamin synthesis) [13, 14]. Here, we present a summary of classification and a set of features for Thermus sp. CCB_US3_UF1, together with the description of the complete genom ...
Interaction-based evolution: how natural selection and nonrandom
... revolutions have raised a host of critical new questions, through empirical findings that the modern synthesis fails to explain: for example, the discovery of de novo genes; the immense constructive role of transposable elements in evolution; genetic variance and biochemical activity that go far bey ...
... revolutions have raised a host of critical new questions, through empirical findings that the modern synthesis fails to explain: for example, the discovery of de novo genes; the immense constructive role of transposable elements in evolution; genetic variance and biochemical activity that go far bey ...
Hemoglobin A2: origin, evolution, and aftermath
... P-globin gene. When the in vitro transcription of non-aglobin genes was compared, it was found that P-, E-, and y-globin genes are transcribed with equal efficiencies, but that the transcription of the 6-globin gene is far less efficient.” Humphries et a P compared the expression of a-, P-, and &glo ...
... P-globin gene. When the in vitro transcription of non-aglobin genes was compared, it was found that P-, E-, and y-globin genes are transcribed with equal efficiencies, but that the transcription of the 6-globin gene is far less efficient.” Humphries et a P compared the expression of a-, P-, and &glo ...
x-linked female-sterile loci in drosophzla melanogaster
... per locus from the two independent screens are similar (Figure 1). Using the data from these mutagenesis screens, the number of loci on the X chromosome has been estimated to be about 100 (KING and MOHLER 1975) (however, see DISCUSSION for a modification of this estimate). If this estimate reflects ...
... per locus from the two independent screens are similar (Figure 1). Using the data from these mutagenesis screens, the number of loci on the X chromosome has been estimated to be about 100 (KING and MOHLER 1975) (however, see DISCUSSION for a modification of this estimate). If this estimate reflects ...
Identity-by-descent filtering of exome sequence data for disease
... high error rates of variant calls in NGS data. In this work, we describe a procedure for efficiently filtering exome sequencing data obtained from two or more affected siblings with an autosomal recessive Mendelian disorder based upon the identification of chromosomal regions identical by descent (I ...
... high error rates of variant calls in NGS data. In this work, we describe a procedure for efficiently filtering exome sequencing data obtained from two or more affected siblings with an autosomal recessive Mendelian disorder based upon the identification of chromosomal regions identical by descent (I ...
Widespread expression of the bovine Agouti gene results from at
... 1999). We and others (Klungland et al., 1995; Rouzaud et al., 2000) have identified four Extension alleles including those with loss-of-function (Mc1re) and gain-offunction (Mc1rED) which lead to pheomelanic and eumelanic coat colour, respectively. Three of them were suggested by genetics analysis ( ...
... 1999). We and others (Klungland et al., 1995; Rouzaud et al., 2000) have identified four Extension alleles including those with loss-of-function (Mc1re) and gain-offunction (Mc1rED) which lead to pheomelanic and eumelanic coat colour, respectively. Three of them were suggested by genetics analysis ( ...
Dominant Suppressors of Yeast Actin Mutations That Are Reciprocally Suppressed.
... a Crosses were made between actl-Z tub2-201 sac segregants (derived from the diploid mutants listed) and wild-type strain DBY877, DBY2057, DBY2065, or DBY2066. ' The presence of tetrads with 0":4-, and the lack of tetrads with 3+:1-, indicates that two T s mutations are segregating. When two T s mut ...
... a Crosses were made between actl-Z tub2-201 sac segregants (derived from the diploid mutants listed) and wild-type strain DBY877, DBY2057, DBY2065, or DBY2066. ' The presence of tetrads with 0":4-, and the lack of tetrads with 3+:1-, indicates that two T s mutations are segregating. When two T s mut ...
Phenotypic plasticity in development and evolution
... not necessarily translate into phenotypic variation: this is the case of many selectively neutral genetic markers, like microsatellite DNA. Standing genetic variation that does not contribute to phenotypic variation under standard conditions, while having the potential to modify the phenotype follow ...
... not necessarily translate into phenotypic variation: this is the case of many selectively neutral genetic markers, like microsatellite DNA. Standing genetic variation that does not contribute to phenotypic variation under standard conditions, while having the potential to modify the phenotype follow ...
PCR-based Markers and Cut Flower Longevity in Carnation
... RAPD bands were not able to discriminate the two groups. This could be explained by the high genetic similarity of this material, coming from the same breeder and selected since 1950 for longevity. More effective markers should be identified for the assisted selection of vase life characters in carn ...
... RAPD bands were not able to discriminate the two groups. This could be explained by the high genetic similarity of this material, coming from the same breeder and selected since 1950 for longevity. More effective markers should be identified for the assisted selection of vase life characters in carn ...